RGD Reference Report - A revised nomenclature for the human and rodent alpha-tubulin gene family. - Rat Genome Database

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A revised nomenclature for the human and rodent alpha-tubulin gene family.

Authors: Khodiyar, VK  Maltais, LJ  Sneddon, KM  Smith, JR  Shimoyama, M  Cabral, F  Dumontet, C  Dutcher, SK  Harvey, RJ  Lafanechere, L  Murray, JM  Nogales, E  Piquemal, D  Stanchi, F  Povey, S  Lovering, RC  Lovering, Ruth C 
Citation: Khodiyar VK, etal., Genomics. 2007 May 31;.
RGD ID: 1626098
Pubmed: PMID:17543498   (View Abstract at PubMed)
DOI: DOI:10.1016/j.ygeno.2007.04.008   (Journal Full-text)

An essential component of microtubules, alpha-tubulin is also a multigene family in many species. An orthology-based nomenclature for this gene family has previously been difficult to assign due to incomplete genome builds and the high degree of sequence similarity between members of this family. Using the current genome builds, sequence analysis of human, mouse, and rat alpha-tubulin genes has enabled an updated nomenclature to be generated. This revised nomenclature provides a unified language for the discussion of these genes in mammalian species; it has been approved by the gene nomenclature committees of the three species and is supported by researchers in the field.



Objects referenced in this article
Gene Tuba1a tubulin, alpha 1A Rattus norvegicus
Gene Tuba1b tubulin, alpha 1B Rattus norvegicus
Gene Tuba1c tubulin, alpha 1C Rattus norvegicus
Gene Tuba3a tubulin, alpha 3A Rattus norvegicus
Gene Tuba3b tubulin, alpha 3B Rattus norvegicus
Gene Tuba4a tubulin, alpha 4A Rattus norvegicus
Gene Tuba8 tubulin, alpha 8 Rattus norvegicus
Gene Tubal3 tubulin, alpha-like 3 Rattus norvegicus

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