Insglur4 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Insglur4 (Insulin/glucose ratio QTL 4) Rattus norvegicus

Symbol: Insglur4
Name: Insulin/glucose ratio QTL 4
RGD ID: 9590080
Previously known as: insulin resistance
Trait: blood insulin amount   (VT:0001560)    
Measurement Type: calculated plasma insulin level   (CMO:0002170)    
LOD Score: 28.7
P Value: 0.001
Variance: 23.2
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.023,686,308 - 48,686,308RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0222,817,824 - 67,817,824RGD_MAPPER_PIPELINERnor5.0
Cross Type: intercross
Strains Crossed: F344/IcoCrlf LOU/NimrOlaHsd 



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Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Quantitative Trait Loci Influencing Abdominal Fat Deposition and Functional Variability of the HPA Axis in the Rat. Marissal-Arvy N, etal., Horm Metab Res. 2014 Jul 8.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Peak: (D2Rat124)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2226,917,817 - 26,918,153 (+)MAPPER
mRatBN7.28116,760,064 - 116,760,124 (-)MAPPER
mRatBN7.2226,917,948 - 26,918,153 (+)MAPPER
Rnor_6.0226,186,318 - 26,186,520NCBI
Rnor_6.0226,186,097 - 26,186,520NCBI
Rnor_5.0245,317,834 - 45,318,036UniSTS
Rnor_5.0245,317,613 - 45,318,036UniSTS
Celera222,980,838 - 22,981,040UniSTS
RH 3.4 Map213.3RGD
RH 3.4 Map213.3UniSTS
RH 2.0 Map278.1RGD
SHRSP x BN Map27.2098RGD
FHH x ACI Map212.9999RGD


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general confidence interval 23.0-24.7 Mb 8694157
qtl_general number of animals used: 93 F2 males and 94 F2 females 8694157
qtl_general measurement method: at the end of the HPA axis function experiment, animals were fasted overnight, blood samples collected (T0), 2 min later rats were injected with 4IU/kg insulin and blood samples taken T0+30 min; insulin resistance estimated as the percentage of decrease in glycemia 8694157
qtl_general software package used: MultiQTL software 8694157
qtl_general an additional peak at D2Mit11 with confidence interval 170.9-188.8 Mb was observed 8694157