Alc26 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Alc26 (Alcohol consumption QTL 26) Rattus norvegicus

Symbol: Alc26
Name: Alcohol consumption QTL 26
RGD ID: 8693622
Trait: drinking behavior trait   (VT:0001422)    
Measurement Type: calculated ethanol drink intake rate   (CMO:0001615)    
LOD Score: 2.4
P Value: 0.667
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.02237,712,398 - 257,579,826RGD_MAPPER_PIPELINERnor6.0
Rnor_5.02256,252,917 - 276,257,792RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.42230,127,295 - 250,896,811RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: BXH/Ipcv HXB/Ipcv 



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Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Measurement Method
scale  (IDA)

Vertebrate Trait

Rat Strain
BXH/Ipcv  (IEA)
HXB/Ipcv  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Is the Alcohol Deprivation Effect Genetically Mediated? Studies with HXB/BXH Recombinant Inbred Rat Strains. Vanderlinden LA, etal., Alcohol Clin Exp Res. 2014 Jun 24. doi: 10.1111/acer.12471.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (rs105495306)
Rat AssemblyChrPosition (strand)Source
Rnor_6.02237,712,398 - 237,712,398RGD
Rnor_5.02256,252,917 - 256,252,917RGD
RGSC_v3.42230,127,295 - 230,127,295RGD
Celera2213,372,588 - 213,372,588RGD
Peak: (rs63999739)
Rat AssemblyChrPosition (strand)Source
Rnor_6.02247,881,962 - 247,881,962RGD
Rnor_5.02266,412,984 - 266,412,984RGD
RGSC_v3.42240,243,053 - 240,243,053RGD
Celera2223,073,568 - 223,073,568RGD
Flank 2: (rs13448492)
Rat AssemblyChrPosition (strand)Source
Rnor_6.02257,579,826 - 257,579,826RGD
Rnor_5.02276,257,792 - 276,257,792RGD
RGSC_v3.42250,896,811 - 250,896,811RGD
Celera2233,238,119 - 233,238,119RGD


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general measurement method: rats were given 10% EtOH for 1 week, then for 7 weeks they were given 2-bottle choice of water and EtOH followed by 2 week period of only water (alcohol deprivation); then 2 weeks of 2-bottle choice of water and EtOH followed by second 2 weeks of alcohol deprivation then 2 weeks of 2-bottle choice of water and EtOH followed by third 2 weeks of alcohol deprivation and 1 week of 2-bottle choice of water and EtOH 8663441
qtl_general water and alcohol consumption were measured by weight 8663441
qtl_general alcohol deprivation effect (ADE) was calculated as the amount of alcohol consumed (g/kg) during 24 hrs after deprivation minus average daily amount consumed in the week before deprivation period 8663441
qtl_general this QTL correlates to week 2 pre-ADE alcohol consumption 8663441
qtl_general software used: ANOVA 8663441
qtl_general number of animals used: 70-100 days old males from HXB/BXH RI strains and the parental BN-Lx/CubPrin, SHR/OlaIpcvPrin 8663441
qtl_general spans 256.4-276.4 Mb 8663441