Vie3 QTL Report (Rattus norvegicus) - Rat Genome Database

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Pathways

QTL: Vie3 (Viral induced encephalitis QTL 3) Rattus norvegicus

Symbol: Vie3
Name: Viral induced encephalitis QTL 3
RGD ID: 8552796
Previously known as: Hse4
Trait: brain integrity trait   (VT:0010579)    
Measurement Type: encephalitis incidence/prevalence measurement   (CMO:0002361)    
LOD Score: 2.6
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2696,833,997 - 140,994,061RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.06101,207,574 - 147,991,367RGD_MAPPER_PIPELINERnor_6.0
Rnor_5.06110,589,216 - 156,897,508RGD_MAPPER_PIPELINERnor_5.0
RGSC_v3.46100,709,370 - 147,636,619RGD_MAPPER_PIPELINERGSC_v3.4
Cross Type: intercross
Strains Crossed: DA/ZtmKini PVG.1AV1/Kini 



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Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. The calcitonin receptor gene is a candidate for regulation of susceptibility to herpes simplex type 1 neuronal infection leading to encephalitis in rat. Abdelmagid N, etal., PLoS Pathog. 2012;8(6):e1002753. doi: 10.1371/journal.ppat.1002753. Epub 2012 Jun 28.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (D6Rat100)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2696,833,997 - 96,834,179 (+)MAPPER
Rnor_6.06101,207,574 - 101,207,755NCBI
Rnor_5.06110,589,216 - 110,589,397UniSTS
RGSC_v3.46100,709,370 - 100,709,706RGD
RGSC_v3.46100,709,526 - 100,709,707UniSTS
Celera695,243,138 - 95,243,319UniSTS
RGSC_v3.16100,712,826 - 100,713,162RGD
RH 3.4 Map6677.0RGD
RH 3.4 Map6677.0UniSTS
SHRSP x BN Map657.2998RGD
SHRSP x BN Map657.2998UniSTS
FHH x ACI Map668.02RGD
Peak: (D6Rat152)
Rat AssemblyChrPosition (strand)Source
mRatBN7.26136,137,889 - 136,138,031 (+)MAPPER
Rnor_6.06142,945,176 - 142,945,317NCBI
Rnor_5.06151,903,878 - 151,904,019UniSTS
RGSC_v3.46142,449,309 - 142,449,451RGD
RGSC_v3.46142,449,310 - 142,449,451UniSTS
Celera6133,815,948 - 133,816,092UniSTS
RGSC_v3.16142,455,497 - 142,455,638RGD
RH 3.4 Map6946.81RGD
RH 3.4 Map6946.81UniSTS
RH 2.0 Map61204.4RGD
FHH x ACI Map6102.91RGD


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general software used: R/qtl package 7240516
qtl_general measurement method: 45 days old rats were infected in the whiskers area with 2X106 PFU of HSV-1, incidence of Herpes simplex encephalitis (HSE) phenotypes such as difficulties in balance and coordination, paralysis, weight loss and death were observed for 10 days 7240516
qtl_general number of animals used: 120 F2 female rats 7240516
qtl_general inducing agent: neurovirulent Herpes simplex type 1 virus (HSV-1 strain I-2762) 7240516
qtl_general confidence interval 147.9 Mb till the end 7240516