Strs5 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Strs5 (Sensitivity to stroke QTL 5) Rattus norvegicus

Symbol: Strs5
Name: Sensitivity to stroke QTL 5
RGD ID: 7411719
Trait: cerebrum integrity trait   (VT:0010549)    
Measurement Type: percentage of study population developing cerebrovascular lesions during a period of time   (CMO:0000932)    
LOD Score: 9.4
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21849,999,958 - 65,845,095RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01851,609,032 - 67,502,266RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01850,804,228 - 66,665,205RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41852,290,789 - 69,013,448RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: SHR/Izm SHRSP/Izm 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
Stroke  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
SHR/Izm  (IEA)
SHRSP/Izm  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Two genomic regions of chromosomes 1 and 18 explain most of the stroke susceptibility under salt loading in stroke-prone spontaneously hypertensive rat/Izm. Gandolgor TA, etal., Hypertension. 2013 Jul;62(1):55-61. doi: 10.1161/HYPERTENSIONAHA.111.00488. Epub 2013 May 20.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1585254Vdac1-ps11voltage-dependent anion channel 1, pseudogene 11185000323150005074Rat
1308614Aldh7a1aldehyde dehydrogenase 7 family, member A1185000324250042193Rat
708448Phaxphosphorylated adaptor for RNA export185005313350069823Rat
1561039Spmip10sperm microtubule inner protein 10185007061050073942Rat
41365840LOC120098251uncharacterized LOC120098251185010415650125611Rat
620522Lmnb1lamin B1185017586150215210Rat
1359308Marchf3membrane associated ring-CH-type finger 3185023721850389343Rat
2299854C18h5orf63similar to human chromosome 5 open reading frame 63185042407950442172Rat
41221436LOC120098149uncharacterized LOC120098149185044203450458966Rat
41272761Mrpl30-ps9mitochondrial ribosomal protein L30, pseudogene 9185058067450581203Rat
11392115LOC108348736nucleophosmin pseudogene185060255250603044Rat
735084Megf10multiple EGF-like domains 10185060523150755441Rat
9186345LOC103694223uncharacterized LOC103694223185072736850744395Rat
6498213Ppp4r1-ps1protein phosphatase 4, regulatory subunit 1, pseudogene 1185079171850793723Rat
41013740LOC120098370small nucleolar RNA SNORA48185080877250808913Rat
1565632Prrc1proline-rich coiled-coil 1185081254850846273Rat
6499660LOC100910150uncharacterized LOC100910150185084779750876513Rat
2300148Ctxn3cortexin 3185093024450940642Rat
6499835LOC100910189uncharacterized LOC100910189185094267750948659Rat
7673459LOC102547870sporulation-specific protein 15-like185104189251063413Rat
41119031LOC120098446U6 spliceosomal RNA185113625651136360Rat
41375324Rpl31-ps8ribosomal protein L31, pseudogene 8185120879251209727Rat
1582966Rpl10-ps8ribosomal protein L10, pseudogene 8185120988651211644Rat
620809Slc12a2solute carrier family 12 member 2185134828251416448Rat
40974709LOC120098445U6 spliceosomal RNA185144715251447238Rat
620910Fbn2fibrillin 2185149967051703976Rat
41325821LOC120098234uncharacterized LOC120098234185172090351728238Rat
7683561LOC102548224uncharacterized LOC102548224185187889351882599Rat
41263870LOC120098199uncharacterized LOC120098199185198367251999725Rat
1311977Slc27a6solute carrier family 27 member 6185204024152099622Rat
41222912LOC120098379small nucleolar RNA SNORA17185210115752101288Rat
1307632Isoc1isochorismatase domain containing 1185215879052179206Rat
41069369LOC120098373small nucleolar RNA SNORA48185228960352289735Rat
2323524Naa50-ps1N(alpha)-acetyltransferase 50, NatE catalytic subunit, pseudogene 1185233697052337537Rat
1308359Adamts19ADAM metallopeptidase with thrombospondin type 1 motif, 19185234644852531245Rat
1312005Minar2membrane integral NOTCH2 associated receptor 2185253971452554465Rat
41282418LOC120098155uncharacterized LOC120098155185255029452553031Rat
1560819Chsy3chondroitin sulfate synthase 3185264435652901257Rat
7500552LOC102548951uncharacterized LOC102548951185343914553494664Rat
1359421Ifgga2l1interferon-gamma-inducible GTPase 2 like 1185376111853770183Rat
41389142Ifgga2l-ps2interferon-gamma-inducible GTPase 2 like, pseudogene 2185378908553794279Rat
1305184Ifgga4linterferon-gamma-inducible GTPase 4 like185383842653854858Rat
1565797Ifgga2l2interferon-gamma-inducible GTPase 2 like 2185387083853890135Rat
7748007Ifgga2l-ps1interferon-gamma-inducible GTPase 2 like, pseudogene 1185390703453909527Rat
628864Smim3small integral membrane protein 3185393001953982339Rat
71023Dctn4dynactin subunit 4185398235554009409Rat
1305770Rbm22RNA binding motif protein 22185401337454024182Rat
1594778Myoz3myozenin 3185402613354046151Rat
620668Synposynaptopodin185404829954106388Rat
41167261LOC120098275uncharacterized LOC120098275185412539654133520Rat
69303Ndst1N-deacetylase and N-sulfotransferase 1185413688754199545Rat
62025Rps14ribosomal protein S14185422785454232638Rat
2313Cd74CD74 molecule185425675754266003Rat
1309850Tcof1treacle ribosome biogenesis factor 1185426701554300324Rat
7546100LOC102550733uncharacterized LOC102550733185433675454348014Rat
1310242Arsiarylsulfatase family, member I185436416054371772Rat
2261Camk2acalcium/calmodulin-dependent protein kinase II alpha185437864254441120Rat
620928Slc6a7solute carrier family 6 member 7185444846454467319Rat
621233Cdx1caudal type homeo box 1185447258754490913Rat
3285Pdgfrbplatelet derived growth factor receptor beta185449996254538840Rat
2425Csf1rcolony stimulating factor 1 receptor185454667354590418Rat
40947909LOC120098110uncharacterized LOC120098110185454967654554826Rat
1560009Hmgxb3HMG-box containing 3185459055854638050Rat
620622Slc26a2solute carrier family 26 member 2185464827654666627Rat
1306835Pde6aphosphodiesterase 6A185467686354748640Rat
41295430LOC120098169uncharacterized LOC120098169185473616654737789Rat
727948Ppargc1bPPARG coactivator 1 beta185475889154861103Rat
4888557Mir3557microRNA 3557185485853754858649Rat
2325365Mir378microRNA 378185485855954858623Rat
41239909LOC120098447U6 spliceosomal RNA185493098054931089Rat
1560471Arhgef37Rho guanine nucleotide exchange factor 37185493525655001017Rat
71098Csnk1a1casein kinase 1, alpha 1185501704955050184Rat
2320730Rps23-ps2ribosomal protein S23, pseudogene 2185509504755095573Rat
10401674Carmncardiac mesoderm enhancer-associated non-coding RNA185509784855118769Rat
2325565Mir145microRNA 145185509964055099727Rat
2325566Mir143microRNA 143185510100655101110Rat
620614Il17binterleukin 17B185514119455145565Rat
1563290Pcyox1lprenylcysteine oxidase 1 like185515063755161334Rat
1585231Grpel2GrpE-like 2, mitochondrial185516783155180073Rat
1311580Afap1l1actin filament associated protein 1-like 1185518378655244174Rat
1565118Ablim3actin binding LIM protein family, member 3185525613555376629Rat
41372130LOC120098202uncharacterized LOC120098202185540050855401347Rat
1309038Sh3tc2SH3 domain and tetratricopeptide repeats 2185541638355477419Rat
41400088LOC120098151uncharacterized LOC120098151185549906955508163Rat
2060Adrb2adrenoceptor beta 2185564245955644501Rat
7512909LOC102556293uncharacterized LOC102556293185565595755676904Rat
2850Htr45-hydroxytryptamine receptor 4185576598155949921Rat
11371572LOC108348797uncharacterized LOC108348797185578286455807163Rat
1311505Fbxo38F-box protein 38185595695056004013Rat
41292884LOC120098287uncharacterized LOC120098287185597921556004282Rat
7509835LOC102547035serine protease inhibitor Kazal-type 9-like185601533656031021Rat
1303077Spink7serine peptidase inhibitor, Kazal type 7185604599656049761Rat
1591057Spink13serine peptidase inhibitor Kazal type 13185606483956206257Rat
2322702Psmd14-ps1proteasome 26S subunit, non-ATPase 14, pseudogene 1185608967356096216Rat
2320365Spink10serine peptidase inhibitor, Kazal type 10185610053556111771Rat
11508213LOC108348798uncharacterized LOC108348798185624247156248072Rat
41187572LOC120098441U6 spliceosomal RNA185634998356350089Rat
1589962Apcdd1APC down-regulated 1185638539856416065Rat
1310109NapgNSF attachment protein gamma185643962056459159Rat
1582973Piezo2piezo-type mechanosensitive ion channel component 2185646844956844984Rat
41170621Trnaa-ggc5transfer RNA alanine (anticodon GGC) 5185689805556898129Rat
621717Txnl1thioredoxin-like 1185712536257155167Rat
619836Wdr7WD repeat domain 7185716548257448568Rat
41138415LOC120098442U6 spliceosomal RNA185737920457379309Rat
11489235LOC108348800uncharacterized LOC108348800185746136957468508Rat
1565894Rpl31l7ribosomal protein L31 like 7185753260857533012Rat
41126198LOC120098227uncharacterized LOC120098227185754185757548461Rat
1594356Rps7-ps4ribosomal protein S7, pseudogene 4185759871757647400Rat
41332966LOC1200984125S ribosomal RNA185765745157657572Rat
1594355Prdx1-ps4peroxiredoxin 1, pseudogene 4185768022257680814Rat
3680St8sia3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3185775434957760839Rat
7609587LOC102553013uncharacterized LOC102553013185782355957827741Rat
1562699RGD1562699RGD1562699185782681557831464Rat
1564677Onecut2one cut homeobox 2185783164757890884Rat
1307556Fechferrochelatase185794512357978327Rat
1307238Nars1asparaginyl-tRNA synthetase 1185798930858005584Rat
1308488Atp8b1ATPase phospholipid transporting 8B1185801638258157213Rat
1587255Spty2d1-ps1SPT2 chromatin protein domain containing 1, pseudogene 1185816465258227747Rat
7552381LOC102553083uncharacterized LOC102553083185825709058286296Rat
41187398LOC120098341U6 spliceosomal RNA185828961858289715Rat
735047Nedd4lNEDD4 like E3 ubiquitin protein ligase185839375958726709Rat
41142472LOC120098306uncharacterized LOC120098306185868582858687512Rat
41393772LOC120098307uncharacterized LOC120098307185869770758707320Rat
4888568Mir3591microRNA 3591185875869058758798Rat
2325577Mir122microRNA 122185875870358758787Rat
41334865LOC120098375small nucleolar RNA SNORA48185876537658765506Rat
1564431Alpk2alpha-kinase 2185877560358906150Rat
41035120LOC120098336uncharacterized LOC120098336185881556058817400Rat
11403005LOC108348801uncharacterized LOC108348801185886018958897832Rat
41045620LOC120098182uncharacterized LOC120098182185893713558941989Rat
1309195Malt1MALT1 paracaspase185894228258996318Rat
40996812LOC120098195uncharacterized LOC120098195185902615459032101Rat
11411640LOC10834885640S ribosomal protein S25 pseudogene185903362859034270Rat
41395188LOC120098256uncharacterized LOC120098256185903613759041329Rat
2323345Rpl13a-ps6ribosomal protein L13A, pseudogene 6185905781659058468Rat
41017389LOC12009825260S acidic ribosomal protein P1-like185906596859068700Rat
1311719Zfp532zinc finger protein 532185908008259203672Rat
1304731OacylO-acyltransferase like185921235459263722Rat
628665Sec11cSEC11 homolog C, signal peptidase complex subunit185932093259337272Rat
621740Grpgastrin releasing peptide185938867959402061Rat
620371Raxretina and anterior neural fold homeobox185946334759467469Rat
1307643Cplx4complexin 4185948136059504716Rat
71020Lman1lectin, mannose-binding, 1185950899659530873Rat
1307670Ccbe1collagen and calcium binding EGF domains 1185957985159823977Rat
11465729LOC108348805uncharacterized LOC108348805185982392859852542Rat
6488390Txnl4a-ps9thioredoxin-like 4A, pseudogene 9185987908759925914Rat
2321524Trappc6b-ps1trafficking protein particle complex subunit 6B, pseudogene 1185994739559948031Rat
1594572Rpl18-ps7ribosomal protein L18, pseudogene 7185996343659964074Rat
1359266Pmaip1phorbol-12-myristate-13-acetate-induced protein 1185998602059992434Rat
7567679LOC102551356uncharacterized LOC102551356186002982260038450Rat
41321002LOC120098399small nucleolar RNA SNORA17186007453260074652Rat
7681870Lsm7-ps1LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated, pseudogene 1186008223760093262Rat
1566303Ptgr2-ps1prostaglandin reductase 2, pseudogene 1186009713760098997Rat
41383976LOC120098209uncharacterized LOC120098209186018363660194583Rat
41314139Gapdh-ps56Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 56186027355160273961Rat
1564795St13-ps1ST13, Hsp70 interacting protein, pseudogene 1186027657260277769Rat
2322845Cycs-ps9cytochrome c, somatic, pseudogene 9186028363560283952Rat
2322794Luc7l3-ps1LUC7-like 3 pre-mRNA splicing factor, pseudogene 1186030551760306759Rat
3057Mc4rmelanocortin 4 receptor186041983260421719Rat
41254053Gapdh-ps57Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 57186045712460458562Rat
40930674LOC120098374small nucleolar RNA SNORA48186052144960521579Rat
41315393LOC120098225NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1-like186056202260562179Rat
41204336LOC120098363small nucleolar RNA SNORA42/SNORA80 family186056304960563183Rat
2715GnalG protein subunit alpha L186062231160762599Rat
41249766Fam136a-ps3family with sequence similarity 136, member A, pseudogene 3186062292560631357Rat
41315866LOC120098241uncharacterized LOC120098241186063690560660960Rat
40940698LOC120098414U2 spliceosomal RNA186065208560652252Rat
41224917LOC120098242uncharacterized LOC120098242186070732560711524Rat
1593500Chmp1bcharged multivesicular body protein 1B186074034960742879Rat
1309184Mppe1metallophosphoesterase 1186076341860781553Rat
628692Impa2inositol monophosphatase 2186083420660867575Rat
41306054LOC120098339uncharacterized LOC120098339186083857560844484Rat
1305106Cideacell death-inducing DFFA-like effector a186089491760920485Rat
1305887Tubb6tubulin, beta 6 class V186094339460953031Rat
1305259Afg3l2AFG3 like matrix AAA peptidase subunit 2186095426860999110Rat
1582858Prelid3aPRELI domain containing 3A186099889861034821Rat
11479093LOC108353173heterogeneous nuclear ribonucleoprotein A3 pseudogene186102871661033474Rat
1305892Spire1spire-type actin nucleation factor 1186104191461171670Rat
41103344LOC120098357U1 spliceosomal RNA186104474161044905Rat
1305183Cep76centrosomal protein 76186117451461208512Rat
1304867Psmg2proteasome assembly chaperone 2186120866961227671Rat
620710Ptpn2protein tyrosine phosphatase, non-receptor type 2186122901261294662Rat
9366255Tmsb10l1thymosin, beta 10 like 1186133109661332947Rat
6490353Seh1lSEH1-like nucleoporin186134698661369987Rat
7633439LOC102552297uncharacterized LOC102552297186136366461373917Rat
1562797Cep192centrosomal protein 192186137393761458405Rat
41107086LOC120098367small nucleolar RNA SNORA33186142409361424221Rat
41187941Tuba1b-ps3tubulin, alpha 1B, pseudogene 3186148541761521355Rat
1587105Ldlrad4low density lipoprotein receptor class A domain containing 4186151925361848403Rat
1562758Gapdh-ps118Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 118186162698861628224Rat
41273283Trmt112-ps1tRNA methyltransferase activator subunit 11-2, pseudogene 1186182926261829727Rat
1359600Fam210afamily with sequence similarity 210, member A186184644761886123Rat
1309242RnmtRNA (guanine-7-) methyltransferase186188623061909775Rat
3058Mc5rmelanocortin 5 receptor186191518861920229Rat
628649Mc2rmelanocortin 2 receptor186200198062015567Rat
7616480LOC102548061uncharacterized LOC102548061186206865262155679Rat
41285070LOC120098190uncharacterized LOC120098190186247060262487267Rat
11465878LOC108348808uncharacterized LOC108348808186249611662509136Rat
11512205LOC108348809uncharacterized LOC108348809186267937362697171Rat
69271Tcf4transcription factor 4186294173963288126Rat
1561424Ccdc68coiled-coil domain containing 68186354182863584122Rat
620114Rab27bRAB27B, member RAS oncogene family186359755463794124Rat
40955792LOC120098422U4 spliceosomal RNA186379633663796423Rat
40983148LOC120098183uncharacterized LOC120098183186380773563810721Rat
1564477Ckap2-ps2cytoskeleton-associated protein 2, pseudogene 2186381875863822861Rat
7550710Dynapl1dynactin associated protein-like 1186386513663868338Rat
1596811Dynapdynactin associated protein186388516463909464Rat
1563837C18h18orf54similar to human chromosome 18 open reading frame 54186406512564090260Rat
1359639Stard6StAR-related lipid transfer domain containing 6186408961864118528Rat
1305212PoliDNA polymerase iota186411677464134373Rat
1595452Mbd2methyl-CpG binding domain protein 2186417400264240795Rat
41071324Polr2k-ps3RNA polymerase II, I and III subunit K, pseudogene 3186424932864249758Rat
1561134Rnf149l1ring finger protein 149 like 1186445159264452974Rat
2323104Hmga1-ps1high mobility group AT-hook 1, pseudogene 1186468714864687453Rat
2321355Rpl37-ps3ribosomal protein L37, pseudogene 3186480459464869547Rat
2492DccDCC netrin 1 receptor186486898765972783Rat
11402245LOC108348868uncharacterized LOC108348868186520005065209636Rat
40942548LOC120098154uncharacterized LOC120098154186563315965639597Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10108D18Mgh11344185564260755642948Ratregion
10647D18Wox12140186037761560377755Ratregion
10648D18Wox13171186037759060377753Ratregion
10667D18Mit17117186076313260763249Ratregion
33856D18Mit10239186040871960408944Ratregion
33884D18Mit8147185979647859796643Ratregion
34043D18Mit16150186169831761698465Ratregion
34182D18Mgh3171186584495065845095Ratregion
34218D18Mgh2213185971223459712417Ratregion
34256D4Mgh18124186205711662057171Ratregion
37412D18Rat40152185933040959330563Ratregion
37514D18Rat43212186357104063571267Ratregion
37548D18Rat52202185853611658536311Ratregion
37568D18Rat55100185253976352539863Ratregion
37628D18Rat41219185659458956594808Ratregion
37738D18Rat57162185229287552293055Ratregion
36638D18Rat14173186393288563933058Ratregion
34975D18Rat13149186363672163636873Ratregion
39610D18Rat91124185846525358465364Ratregion
38146D18Rat50242185146473351464973Ratregion
40670D18Rat87240186314087063141096Ratregion
40682D18Rat85205186514612965146325Ratregion
40710D18Rat89219186072228660722497Ratregion
38556D18Rat54249186543789165438136Ratregion
38850D18Rat56212185100704451007252Ratregion
39000D18Rat61245185880568758805936Ratregion
39308D18Rat73219184999995850000167Ratregion
42048D18Arb3360185564272855643097Ratregion
42050D18Arb5268186076305360763320Ratregion
42052D18Arb6197186037758460377792Ratregion
42054D18Arb7185186319560063195769Ratregion
41284D18Rat86175186548935565489518Ratregion
41404D18Rat88125186336571863365833Ratregion
40908D18Rat90234186218573862185972Ratregion
40944D18Rat92183185151482551515008Ratregion
41660D18Rat124201186490744864907655Ratregion
41770D18Rat137231185167921851679445Ratregion
43121D18Rat138231185909078459091013Ratregion
43123D18Rat126200186402116564021365Ratregion
43151DXRat132201185505409455054132Ratregion
45534D18Got63170186392072763920897Ratregion
45536D18Got62213186090670160906914Ratregion
45537D18Wox6166186113406361134215Ratregion
45540D18Got64223186040871660408939Ratregion
45541D18Wox16152185969518459695364Ratregion
45543D18Got61114185950330559503419Ratregion
45544D18Got58179185708644357086624Ratregion
45545D18Got56110185624702156247133Ratregion
45546D18Got57270185575756855757837Ratregion
45550D18Got53184185542212755422311Ratregion
45551D18Got54197185440165254401849Ratregion
45553D18Got52184185254885052549031Ratregion
60779D18Wox5223185575768955757912Ratregion
60176D18Got50156185006877250068930Ratregion
60177D18Got51129185179909551799226Ratregion
60181D18Got81181185112270351122884Ratregion
629607D18Got60220185791018257910399Ratregion
1578845D18Chm94239185838301258383251Ratregion
1630796D18Wox25152185449832954498481Ratregion
1578887D18Chm98245185782629857826543Ratregion
1578888D18Chm37174185699620956996386Ratregion
1578928D18Chm58188186518591265186096Ratregion
1578944D18Chm95240185844122358441462Ratregion
1578971D18Chm38173185900596059006133Ratregion
1578988D18Chm35198185478055854780754Ratregion
1578997D18Chm100165185794171757941882Ratregion
1579026D18Chm96218185813835658138576Ratregion
1579092D18Chm34190185409583554096025Ratregion
1579127D18Chm97218185808551258085730Ratregion
1579147D18Chm36179185601732056017501Ratregion
1579151D18Chm33194185311605153116249Ratregion
1579162D18Chm99242185755651957556757Ratregion
1628675D18Got110163185595523855955399Ratregion
1629471D18Mco91038186229986662300904Ratregion
1640801D18Got128332186402724764027578Ratregion
1633167D18Got123128186548931765489445Ratregion
1635683D18Got103153185237000252370155Ratregion
5038988RH127448205185464843254648637Ratregion
7206756ha2758634185111049951111133Ratregion
5036563AU048444185185962506259625247Ratregion
5036651AU048720142185813844658138590Ratregion
5035572MC4R478186042046060420938Ratregion
7206184Htr4121185590840455908525Ratregion
5031518AU048064184185283779552837979Ratregion
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5026816RH133642183186117925261179435Ratregion
5029525AI029740180185084893750849117Ratregion
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5035398AI228240201185788395057884151Ratregion
5035470BE108561160186319636663196526Ratregion
5027155RH65263127186095219660952323Ratregion
5029837BI27883398186358381063583908Ratregion
5034986Adrb2384185564299055643374Ratregion
5032825RH135441202185469787354698075Ratregion
5027531AI173486151185518394455184095Ratregion
5024950Mc2r116186200503362005149Ratregion
5025154AU015601228185638679656387024Ratregion
5030405BI288375171185457665954576946Ratregion
5030473BE106644179185646926956469448Ratregion
5030589AA955742136185788562157885757Ratregion
5033359RH138542124186184227861842402Ratregion
5028103X90945156185504742255047578Ratregion
5028199D18Mit140105185456374854563853Ratregion
5033571RH139312196185949029759490493Ratregion
5033775RH140076211185801806958018280Ratregion
5051921RH94735170185564258055642750Ratregion
5056033RH144144156185872414958724305Ratregion
5056201RH144242179185982527459825453Ratregion
5056283RH144289260185495781254958072Ratregion
5051593AW550622100186104237661042476Ratregion
5053851RH142887203186306546063065663Ratregion
5056729RH144546241185915740059157641Ratregion
5051873RH94707190186037758160377763Ratregion
5051923RH94736133185564558255645715Ratregion
5052039RH94805254186041983860420092Ratregion
5054271RH143128149185999218159992332Ratregion
5054399RH143202203185948145959481664Ratregion
5054521RH143272216186407339964073615Ratregion
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5055475RH143823154185405423654054390Ratregion
5055677RH143938125185914426759144392Ratregion
5057898BI283816237185457240254572639Ratregion
5057992BF386416173185902630959027255Ratregion
5055987RH144118264185789293657893200Ratregion
5056061RH144160208185504253655042744Ratregion
5055157RH143638121186118071961181005Ratregion
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5056845RH144614191186073798360738174Ratregion
5056901RH144646157185518338855183545Ratregion
5056939RH144668168185517600355176170Ratregion
5052231D18928106185950904259509148Ratregion
5052295MHAa74a6.seq150185978157559781725Ratregion
5058152BI277637192186136941361369605Ratregion
5056805RH144591153185872907158729224Ratregion
5052673RH142200181186191647961916660Ratregion
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5059000BF387306170185776483057765000Ratregion
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5058206BI277765161185495771854957879Ratregion
5058276BF386932172186102683761027009Ratregion
5058312BI277908190186411400664114196Ratregion
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5052357X80502163185776069257760855Ratregion
5059188BF387606153186102763561027788Ratregion
5050412RH134041180186095282860953009Ratregion
5050564RH134129195185877574458775939Ratregion
5050628RH134166150185402618054026330Ratregion
5050684RH134198198185956000459560202Ratregion
7193120ADRB2888185564328855644176Ratregion
5050904RH134325198185217869752178895Ratregion
5054283RH143135141185442438254424523Ratregion
5054347RH143172110185876799858768108Ratregion
5051681RH94596146185426580754265953Ratregion
5054629RH143334237186135492761356264Ratregion
5050930RH134340192185783888757839079Ratregion
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5044304RH130526197185084918850849385Ratregion
5044694RH130750181185006952750069708Ratregion
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5041102RH128664200185518254155182741Ratregion
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5045668RH131310199185459017854590377Ratregion
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5044572RH130681182185794612857946310Ratregion
5047432RH132324189186104203161042220Ratregion
5047496RH132361220185444795954448179Ratregion
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5048892RH133166219185712690657127125Ratregion
5049000RH133228180185289784952898029Ratregion
5045944RH131469220185788899157889212Ratregion
5047934RH132613182185217751952177701Ratregion
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5047018RH132087214186101814061018354Ratregion
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5047122RH132146215186486922564869440Ratregion
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5048488RH132932181185871669158716872Ratregion
5039802RH127915180185798945257989632Ratregion
5042534RH129492215186424063764240852Ratregion
5042546RH129499208186074167060741878Ratregion
5048632RH133015191185782718557827462Ratregion
5040176RH128133182186086500360865185Ratregion
5042614RH129541191186190663061906821Ratregion
5042100RH129239216186074167060741886Ratregion
5040408RH128266215185712847457128689Ratregion
5043124RH129846165186200201162002176Ratregion
5043378RH129991195185422019454220389Ratregion
5040212RH128154190185149837751498567Ratregion
5040284RH128195198186003374260033940Ratregion
5042646RH129559215186104241061042625Ratregion
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5072504RH136887199185557246255572661Ratregion
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5074384RH137986170185442428354424453Ratregion
5072320RH13678184185518400055184084Ratregion
5074820RH138237122185587119455871316Ratregion
5071802RH135293205186185385761854062Ratregion
5061678BE105826162185465731554657477Ratregion
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5061830AW533757197185646909556469291Ratregion
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5069006AU046785103185842222058422323Ratregion
5070235RH94550172186191785461918026Ratregion
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5069180AU046666226185260546552605691Ratregion
5060196BF400698145186121510561215250Ratregion
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5062516BF403348180185624759556247775Ratregion
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5060208BI279712166185564258055642746Ratregion
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5062448BI288878199186185280561853004Ratregion
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5066142BF407035116185920271259202828Ratregion
5061188BE111197178185504534755045525Ratregion
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5061364BE111683181185513815355138334Ratregion
5061372BI293856160185916645059166610Ratregion
5066500AU048320195185633350456333699Ratregion
5061650BF396987221185788605657886277Ratregion
5086989BE114822155185412800954128164Ratregion
5082271BE119093161185016663550166796Ratregion
5082303BE119145177185717631257176489Ratregion
5086215BF409925151185453983154539982Ratregion
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5089175AU049000248185118633151186579Ratregion
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5088831AU048796167186570772265707889Ratregion
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5090235AU049630148186419293564193083Ratregion
5090239AU049633183185804627958046462Ratregion
5087177AA819654197185914562759145824Ratregion
5082365BE119266151185442340554423556Ratregion
5085339BM390185210185454118654541396Ratregion
5090673AU049893216186290710462907320Ratregion
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5090757AU049945191185906066759060858Ratregion
5088377AU048533125185810420358104328Ratregion
5085314AW534258163186487143364871596Ratregion
5081320RH142092193186086721960867412Ratregion
5085447BM390389172185510271455102886Ratregion
5082483BI274883209185514528055145489Ratregion
5086082BM386044212185509450955094721Ratregion
5080884RH141838208186424281164243019Ratregion
5084620AA946478177185253086452531040Ratregion
5082893BF390349156185264314552643301Ratregion
5081336Ndst1441185414128354141724Ratregion
5083117BF390803151185899664758996798Ratregion
5081555BE117353155186406578664065941Ratregion
5083479BF391404198185196103751961235Ratregion
5086685BM385927172185643998056440152Ratregion
5086707BE107285155186418780864187962Ratregion
5081837BE118490153186541887165419024Ratregion
5085910BM384410186185511487355115059Ratregion
5503294UniSTS:237814203185084598750846190Ratregion
5503296UniSTS:237838320186328689963287219Ratregion
5503784UniSTS:471069118185564299555643113Ratregion
5503908Csf1r342185456783354568481Ratregion
5504121ADRB2sts1455185564343155643886Ratregion
5504666PMC343810P598185405523954055337Ratregion
5504608PMC314306P3270186042065460420924Ratregion
5505867Htr479185588487255884951Ratregion
5506527CSF1R_1770642185458976554590407Ratregion
5507281fb33h01.x1815185227787252278687Ratregion
5507045UniSTS:224229104185259871152598815Ratregion
5507069UniSTS:224353158185413694854137106Ratregion
5507145UniSTS:224845185185400915954009344Ratregion
5500248AW455934127185444807654448203Ratregion
5500346GDB:201899155186529627165296426Ratregion
5500891STS-Z407940186327565363275991Ratregion
5503300UniSTS:237833200186074091960741119Ratregion
5501217PMC156124P3298186095190660952204Ratregion
5504474PMC219482P283185456689254566975Ratregion
5505144Onecut277185783248857832565Ratregion
5501373STS-X524861389185884672658848115Ratregion
5501778MARC_12115-12116:1004707389:1117185458905554589477Ratregion
5506777G452980185811316258113709Ratregion
5506777G452980185811342158113709Ratregion
5507209UniSTS:225275155185444049954440654Ratregion
Position Markers

Flank 1: (D18Rat73)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21849,999,958 - 50,000,167 (+)MAPPER
Rnor_6.01851,609,032 - 51,609,240NCBI
Rnor_5.01850,804,228 - 50,804,436UniSTS
RGSC_v3.41852,290,789 - 52,291,194RGD
RGSC_v3.41852,290,924 - 52,291,132UniSTS
RGSC_v3.11852,336,284 - 52,336,689RGD
Celera1848,145,282 - 48,145,490UniSTS
SHRSP x BN Map1819.1999RGD
SHRSP x BN Map1819.1999UniSTS
Peak: (D18Rat41)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21856,594,589 - 56,594,808 (+)MAPPER
Rnor_6.01858,476,128 - 58,476,346NCBI
Rnor_5.01857,699,045 - 57,699,263UniSTS
RGSC_v3.41859,279,067 - 59,279,285UniSTS
RGSC_v3.41859,279,066 - 59,279,285RGD
RGSC_v3.11859,352,268 - 59,352,486RGD
Celera1854,738,316 - 54,738,534UniSTS
RH 3.4 Map18558.8RGD
RH 3.4 Map18558.8UniSTS
RH 2.0 Map18343.2RGD
SHRSP x BN Map1825.0199RGD
FHH x ACI Map1839.06RGD
Cytogenetic Map18q12.1UniSTS
Flank 2: (D18Mgh3)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21865,844,950 - 65,845,095 (+)MAPPER
Rnor_6.01867,502,122 - 67,502,266NCBI
Rnor_5.01866,665,061 - 66,665,205UniSTS
RGSC_v3.41869,013,303 - 69,013,448RGD
RGSC_v3.41869,013,304 - 69,013,448UniSTS
RGSC_v3.11869,086,504 - 69,086,649RGD
Celera1863,873,881 - 63,874,025UniSTS
RH 3.4 Map18685.3UniSTS
RH 3.4 Map18685.3RGD
RH 2.0 Map18224.7RGD
SHRSP x BN Map1838.7499RGD
FHH x ACI Map1848.5199RGD
Cytogenetic Map18q12.2UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
1331730Scl27Serum cholesterol level QTL 273.826blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)185229287559796643Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)185470976983828827Rat
1331736Bp227Blood pressure QTL 2272.791arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)184671876359796643Rat
1300125Rf26Renal function QTL 263.2urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)185253986365844950Rat
631834Sach3Saccharin preference QTL 33.90.01consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)185880568763636873Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184334502283828827Rat
1331727Bp237Blood pressure QTL 2373.053arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940861698465Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184664067583828827Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184664067583828827Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)185971241776477814Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)182979296574792965Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1331770Bp234Blood pressure QTL 2343.807arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185979647871893566Rat
61360EaeyExperimental allergic encephalomyelitis QTL y3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)184698893960377753Rat
2300177Bmd65Bone mineral density QTL 6519.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
2301969Bp324Blood pressure QTL 3244.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)185971241776477814Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183135940883218561Rat
12880368Bw187Body weight QTL 1870.045body mass (VT:0001259)body weight (CMO:0000012)185253976376104388Rat
724542Kidm2Kidney mass QTL 22.6kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)185917211583828827Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183819245583192455Rat
2293658Bmd23Bone mineral density QTL 237.30.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)185146473363636873Rat
1359020Ppulsi2Prepulse inhibition QTL 22.71prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)185229287573997283Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18420794160377792Rat
2312600Bp341Blood pressure QTL 3410.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)185933040970263868Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)182979296574792965Rat
1331752Bw27Body weight QTL 272.963body mass (VT:0001259)body weight (CMO:0000012)185229287565845095Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194429952293055Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182979296574792965Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)185253976376104388Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)185253976376104388Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)184852004483828827Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)185253976376104388Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183127168160377755Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)185253976376104388Rat
61384Bp48Blood pressure QTL 4819.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186062231177209844Rat
1331806Bp229Blood pressure QTL 2294.36484arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184671876357867167Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185253976376104388Rat
12904073Kidm71Kidney mass QTL 710.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)185253976376104388Rat
1331780Bp238Blood pressure QTL 2383.269arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184671876359796643Rat
6903353Bp353Blood pressure QTL 3532.8arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)185979647883828827Rat
738008Hcar14Hepatocarcinoma resistance QTL 144.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion number (CMO:0001462)185146473383218561Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183135940859796643Rat
6903356Bp354Blood pressure QTL 3544.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185979647883828827Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183587072380870723Rat
6903345Bp349Blood pressure QTL 3493.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184671893559796478Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat
6903347Bp350Blood pressure QTL 3504.4arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135953059796478Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184664067583828827Rat
6903349Bp351Blood pressure QTL 3513.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184671893559796478Rat
631509Sald2Serum aldosterone level QTL 22.9blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)185253976369140759Rat
2300157Bmd66Bone mineral density QTL 6613.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
738005Anxrr11Anxiety related response QTL 113.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)183003981375039813Rat
6903351Bp352Blood pressure QTL 3523.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184671893559796478Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183139332077209694Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
2293704Bss35Bone structure and strength QTL 354.590.0002femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)182896485373964853Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)182979296574792965Rat
1600375Mcs22Mammary carcinoma susceptibility QTL 223.3mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)185253976363933058Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)184852004483828827Rat
1598826Anxrr20Anxiety related response QTL 203.04body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)184143297183828827Rat
631675Iddm15Insulin dependent diabetes mellitus QTL 15urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)186062231177209844Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183135940870263868Rat
7411719Strs5Sensitivity to stroke QTL 59.4cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)184999995865845095Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general number of animals used: 140 males and 155 females F2 animals 7411685
qtl_general measurement method: baseline blood pressure was taken at 12 weeks of age by tail-cuff method then 1% salt was given in drinking water and blood pressure measured after 2 weeks and animals checked for signs of cerebral stroke like paralysis, twitch, akinesia and hyper-irritability) and stroke latency were analyzed 7411685
qtl_general software used: MapManager QTX version 20 7411685
qtl_general no overlapping QTLs for blood pressure were observed in this region 7411685
qtl_general multiple blocks of different haplotypes were found in this region in SHRSP/Izm and SHR/Izm 7411685