Emca11 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Emca11 (Estrogen-induced mammary cancer QTL 11) Rattus norvegicus

Symbol: Emca11
Name: Estrogen-induced mammary cancer QTL 11
RGD ID: 7394708
Previously known as: Emca8.1
Trait: mammary gland integrity trait   (VT:0010552)    
Measurement Type: mammary tumor number   (CMO:0000343)    
LOD Score: Not Available
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2599,753,548 - 113,061,097RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.05103,580,245 - 117,037,276RGD_MAPPER_PIPELINERnor6.0
Rnor_5.05107,580,080 - 120,980,183RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.45104,231,741 - 118,805,723RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: ACI.BN-(D5Rat60-D5Rat115)/Shul 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Cdkn2a is a candidate Gene for Emca11
Cdkn2b is a candidate Gene for Emca11

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Mapping of three genetic determinants of susceptibility to estrogen-induced mammary cancer within the Emca8 locus on rat chromosome 5. Schaffer BS, etal., Cancer Prev Res (Phila). 2013 Jan;6(1):59-69. doi: 10.1158/1940-6207.CAPR-12-0346-T. Epub 2012 Nov 14.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
620276Sh3gl2SH3 domain containing GRB2 like 2, endophilin A159965318999827500Rat
1306439Adamtsl1ADAMTS-like 1599964406100919786Rat
1583685Saxo1stabilizer of axonemal microtubules 15100937134101093308Rat
619804RragaRas-related GTP binding A5101113341101114936Rat
15203474Haus6family with sequence similarity 29, member A5101116532101156396Rat
41394140LOC120103266small Cajal body-specific RNA 85101124125101124255Rat
728889Plin2perilipin 25101156643101211738Rat
7660377LOC102547623uncharacterized LOC1025476235101226928101245243Rat
1308489Dennd4cDENN domain containing 4C5101272298101369529Rat
3602Rps6ribosomal protein S65101371716101374576Rat
1304629Acer2alkaline ceramidase 25101391830101442615Rat
11473324LOC10835110240S ribosomal protein S20 pseudogene5101460139101460978Rat
628650Slc24a2solute carrier family 24 member 25101499536101739337Rat
41055101LOC120102905uncharacterized LOC1201029055101831467101846644Rat
11459931LOC108350995uncharacterized LOC1083509955102119628102128446Rat
41183840LOC120102906uncharacterized LOC1201029065102229484102238875Rat
620940Mllt3MLLT3, super elongation complex subunit5102259075102515447Rat
41316176LOC120103312small nucleolar RNA SNORA175102483194102483318Rat
1311849Focadfocadhesin5102564560102886587Rat
1310339Hacd43-hydroxyacyl-CoA dehydratase 45102887597102915376Rat
2865Ifnb1interferon beta 15103020969103021523Rat
1306334Ifna4interferon, alpha 45103069483103070052Rat
1306135Ifna1interferon, alpha 15103095767103098260Rat
1589875Ifna7l-ps1interferon, alpha 7 like, pseudogene 15103104672103105585Rat
41171666LOC120103203U6 spliceosomal RNA5103109366103109474Rat
1561246RGD1561246similar to put. precursor MuIFN-alpha 55103144519103145654Rat
1359312Ifna5interferon, alpha 55103187852103188430Rat
1561827RGD1561827similar to Interferon alpha-1 precursor5103196737103197803Rat
1565225Ifna16l1interferon, alpha 16-like 15103216368103216984Rat
6487214LOC100912356interferon alpha-1-like5103227820103230500Rat
1311425Ifna2interferon alpha 25103258617103259195Rat
6502836LOC100909643interferon alpha-1-like5103273737103275988Rat
6487699LOC100912314interferon alpha-1-like5103285510103288640Rat
1559679RGD1559679similar to Interferon alpha-1 precursor5103300554103306107Rat
1583724Ifna1-ps1interferon, alpha 1, pseudogene 15103320390103322719Rat
41029367Rpl27a-ps12ribosomal protein L27a,pseudogene 125103328721103329166Rat
1304814Klhl9kelch-like family member 95103333747103337931Rat
1591738Rps24-ps10ribosomal protein S24, pseudogene 105103343786103344309Rat
41279671LOC120103158interferon alpha-12-like5103378576103379147Rat
41164037LOC120103159interferon alpha-12-like5103407135103407884Rat
41162071LOC120103160interferon alpha-12-like5103426092103427016Rat
41097131LOC120103161interferon alpha-12-like5103441204103442180Rat
40975974LOC120103162interferon alpha-1-like5103455380103455934Rat
1560539RGD1560539similar to interferon alpha 8/6 precursor; IFNa8/6 (B6)5103476362103477211Rat
41024711LOC120103163interferon alpha-12-like5103494442103495077Rat
41140167LOC120103164interferon alpha-12-like5103509610103510260Rat
6492384LOC100911527interferon alpha-12-like5103524733103525302Rat
41074433LOC120103372U4 spliceosomal RNA5103532146103532302Rat
1565065Ifneinterferon, epsilon5103538001103627561Rat
4888605Mir3554microRNA 35545103599032103599149Rat
2325391Mir31microRNA 315103599038103599143Rat
1583723Nmt1-ps1N-myristoyltransferase 1, pseudogene 15103658873103662295Rat
11413299LOC108350998uncharacterized LOC1083509985103757997103779881Rat
2318341LOC100362345hypothetical protein LOC1003623455103767094103767986Rat
1310114Mtapmethylthioadenosine phosphorylase5103873020103939406Rat
41097146LOC120102907uncharacterized LOC1201029075103901281103925151Rat
41229778LOC120103317small nucleolar RNA SNORA175103919376103919499Rat
41034517Gskip-ps1GSK3B interacting protein, pseudogene 15103941903103943310Rat
2323Cdkn2acyclin-dependent kinase inhibitor 2A5103984949103992143Rat
40993322LOC120102909uncharacterized LOC1201029095104003107104016993Rat
2324Cdkn2bcyclin-dependent kinase inhibitor 2B5104009839104019082Rat
7697358LOC102552523uncharacterized LOC1025525235104019105104127037Rat
1588220Hspd1-ps14heat shock protein family D (Hsp60) member 1, pseudogene 145104129384104131678Rat
41260363LOC120102910uncharacterized LOC1201029105104171383104185974Rat
9404082LOC103692411uncharacterized LOC1036924115104410856104415793Rat
1309796Dmrta1DMRT-like family A15104415893104422433Rat
1584925Lmntd1-ps1lamin tail domain containing 1, pseudogene 15104595779104597302Rat
1560729RGD1560729similar to ribosomal protein S245104729321104730083Rat
1563227Zfp352zinc finger protein 3525104946243104948087Rat
1310095Zfp353zinc finger protein 3535105075038105077359Rat
1583722Eef1g-ps13eukaryotic translation elongation factor 1 gamma, pseudogene 135105085925105111382Rat
1585888Vdac1-ps2voltage-dependent anion channel 1, pseudogene 25105313273105321698Rat
41388855Rnu6-698RNA, U6 small nuclear 6985105346075105346181Rat
6498356Ktn1-ps1kinectin 1, pseudogene 15105565480105575498Rat
41255483Ppia-ps8peptidylprolyl isomerase A, pseudogene 85105600882105603060Rat
41097241LOC120103318small nucleolar RNA SNORA175105738478105738609Rat
1584923Rps7-ps19ribosomal protein S7, pseudogene 195105902114105902692Rat
628611Elavl2ELAV like RNA binding protein 25105960872106086539Rat
41069231LOC120103166uncharacterized LOC1201031665106108110106109796Rat
41143086LOC120103387U6 spliceosomal RNA5106129987106130093Rat
7697001Hmgb1-ps10high-mobility group box 1, pseudogene 105106228556106229116Rat
7592700LOC102554351uncharacterized LOC1025543515106358753106371776Rat
6498231Hspd1-ps33heat shock protein family D (Hsp60) member 1, pseudogene 335106398781106403426Rat
40944816LOC120102913uncharacterized LOC1201029135106613937106645065Rat
2324467Izumo3IZUMO family member 35106874321106876978Rat
11416818LOC108351001uncharacterized LOC1083510015106877052106903186Rat
1560983Hnrnpa1-ps24heterogeneous nuclear ribonucleoprotein A1, pseudogene 245106906066106907230Rat
2323226Spcs2-ps1signal peptidase complex subunit 2, pseudogene 15106913633106915036Rat
11418076LOC108351000uncharacterized LOC1083510005106922423106936905Rat
1583529Cks1lCDC28 protein kinase regulatory subunit 1-like5106982447106983199Rat
1561150RGD1561150similar to CPN10-like protein5107131587107131895Rat
41136247Rpl5-ps11ribosomal protein L5, pseudogene 115107212048107217257Rat
41394794LOC120103236U6 spliceosomal RNA5107652473107652571Rat
1592090Snu13-ps4small nuclear ribonucleoprotein 13, pseudogene 45107912017107912407Rat
41074883Tusc1tumor suppressor candidate 15108089952108091636Rat
7543605LOC102546952uncharacterized LOC1025469525108270998108359486Rat
41358010Rpl19-ps7ribosomal protein L19, pseudogene 75108333257108335787Rat
9284656LOC103692415uncharacterized LOC1036924155108723428108734153Rat
41215040LOC120102919uncharacterized LOC1201029195108831467108907138Rat
41235371Rpl8-ps5ribosomal protein L8, pseudogene 55109207408109230540Rat
1560251Caap1caspase activity and apoptosis inhibitor 15109313253109414323Rat
40937684LOC120102920uncharacterized LOC1201029205109330329109338769Rat
621245Plaaphospholipase A2, activating protein5109428600109460373Rat
1359704Ift74intraflagellar transport 745109460372109563839Rat
1591722Lrrc19leucine rich repeat containing 195109497503109502488Rat
2325363Mir872microRNA 8725109539086109539166Rat
620980TekTEK receptor tyrosine kinase5109607077109733805Rat
1563332Eqtnequatorin5109734495109762048Rat
1311787Mysm1myb-like, SWIRM and MPN domains 15109761345109826652Rat
40989424LOC120103252small nucleolar RNA SNORA705109807447109807582Rat
11418089LOC108351004uncharacterized LOC1083510045109851042109866282Rat
11383635LOC108351136uncharacterized LOC1083511365109866403109876222Rat
41394229LOC120102921uncharacterized LOC1201029215109883550109887133Rat
2943JunJun proto-oncogene, AP-1 transcription factor subunit5109894175109897268Rat
6494360LOC100911221uncharacterized LOC1009112215109897523109949196Rat
41358446LOC120102922uncharacterized LOC1201029225109999528110003332Rat
7593337LOC102550339uncharacterized LOC1025503395110107244110110709Rat
40929618LOC120102923uncharacterized LOC1201029235110179996110186201Rat
41402458LOC120102924uncharacterized LOC1201029245110208856110225659Rat
41145702LOC120103235U1 spliceosomal RNA5110355813110355974Rat
1359429FggyFGGY carbohydrate kinase domain containing5110398866110786019Rat
41167909LOC120102926uncharacterized LOC1201029265110586644110592691Rat
9417869LOC103692418uncharacterized LOC1036924185110605125110712729Rat
41141437LOC120102927uncharacterized LOC1201029275110790119110818856Rat
41241770LOC120102925uncharacterized LOC1201029255110819794110824522Rat
1309987Hook1hook microtubule-tethering protein 15110824501110887791Rat
6486125LOC100912642cytochrome P450 2J3-like5110908195110930402Rat
1563215Cyp2j10cytochrome P450, family 2, subfamily j, polypeptide 105110960319110995220Rat
40982088Cyp2j16-ps1cytochrome P450, family 2, subfamily j, polypeptide 16, pseudogene 15111007780111057797Rat
1561242Cyp2j16cytochrome P450, family 2, subfamily j, polypeptide 165111089438111138918Rat
620007Cyp2j4cytochrome P450, family 2, subfamily j, polypeptide 45111179981111207490Rat
631442Cyp2j3cytochrome P450, family 2, subfamily j, polypeptide 35111219921111244987Rat
11381498LOC108351103ferritin light chain 1 pseudogene5111247525111248020Rat
1560146C5h1orf87similar to human chromosome 1 open reading frame 875111342381111411576Rat
41012570LOC120103241U7 small nuclear RNA5111397995111398057Rat
41316576LOC120103249U7 small nuclear RNA5111531651111531712Rat
41245849LOC120103242U7 small nuclear RNA5111531726111531787Rat
1597743Gid8-ps1GID complex subunit 8 homolog, pseudogene 15111562436111563265Rat
1592089Tbc1d5-ps1TBC1 domain family, member 5, pseudogene 15111564652111573058Rat
40966355LOC120103290small nucleolar RNA SNORA485111718328111718474Rat
7502785LOC102553524uncharacterized LOC1025535245112230510112246625Rat
41175373LOC120103115uncharacterized LOC1201031155112244680112248682Rat
41107926LOC120103114uncharacterized LOC1201031145112416267112442856Rat
3170Nfianuclear factor I/A5112436655112781878Rat
41023677LOC120103113uncharacterized LOC1201031135112492479112512005Rat
11413852LOC108351005uncharacterized LOC1083510055112797944112805529Rat
41046330LOC120103278small nucleolar RNA SNORA95112966475112966607Rat
2318487LOC100362298ribosomal protein S18-like5112997100112997655Rat
1305442Tm2d1TM2 domain containing 15113020760113062370Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10321D5Lev171235103991975103992098Ratregion
10826D5Mgh231225109897808109897936Ratregion
10827D5Lev152925109894810109895102Ratregion
34041D5Mit51445104250862104251008Ratregion
37644D5Rat1152035112419535112419733Ratregion
37772DXRat532795103857355103857402Ratregion
36687D5Rat251745113060909113061097Ratregion
35074D5Rat232055102084761102084960Ratregion
35785D5Rat242965101278414101278701Ratregion
40548D5Rat1551545110589458110589608Ratregion
38508D5Rat602465101467719101467963Ratregion
39066D5Rat712155109967940109968152Ratregion
42750D5Rat23123759988536199885595Ratregion
41192D5Rat1522205102816790102817014Ratregion
41424D5Rat1561755110265888110266058Ratregion
42319D5Rat2562405108938288108938528Ratregion
41560D5Rat1531635103689353103689768Ratregion
41560D5Rat1531635103689674103690167Ratregion
41560D5Rat1531635103689997103690167Ratregion
41576D5Rat15115959975354899753708Ratregion
41678D5Rat1971815112426055112426208Ratregion
44552D9Wox211365109552936109552993Ratregion
43934D5Got301335100749175100749308Ratregion
43935D5Got281395101660429101660568Ratregion
43936D5Got1311535101112265101112414Ratregion
43940D5Got271705104607788104607958Ratregion
43942D5Got331385110075805110075940Ratregion
43943D5Got361265109141749109141875Ratregion
43944D5Wox182735112450727112450995Ratregion
43945D5Got391875112936348112936533Ratregion
43948D5Got381475112393083112393230Ratregion
60480D5Got251255106732222106732345Ratregion
60481D5Got312325101703657101703889Ratregion
60483D5Got342775111548415111548692Ratregion
60484D5Got351605111564698111564858Ratregion
60808D5Wox251585109050865109051012Ratregion
69515D5Uwm231865101607489101607673Ratregion
69519D5Uwm251865101387969101388153Ratregion
69521D5Uwm261335101847538101847681Ratregion
69523D5Uwm271455103005080103005247Ratregion
69525D5Uwm281445105629979105630117Ratregion
69527D5Uwm291635109719127109719390Ratregion
62484D5Uia21335105221933105222066Ratregion
66444D5Uia123925107521767107522145Ratregion
629614D5Hmgc11675101374078101374246Ratregion
67361D5Arb172445109897663109897907Ratregion
1627770D5Wox415101502201101502377Ratregion
1635541D5Got2421325111179889111180021Ratregion
1635885D5Got2431275107474818107474945Ratregion
1634628D5Got2411955100113215100113410Ratregion
2315222D16Nkg703195108885691108885972Ratregion
7794818D5Mco472185112175328112175546Ratregion
7192368Elavl2665105963428105963494Ratregion
7206270Mysm16175109793011109793628Ratregion
5035971PMC337033P12255105962737105962962Ratregion
5035971PMC337033P12255105962737105963351Ratregion
5035971PMC337033P12255105962787105962962Ratregion
5036097UniSTS:1412181755102623667102623851Ratregion
5036380Jun4265109896604109897030Ratregion
5039140RH1275351875103766729103766916Ratregion
5036653AU0487272315111945494111945729Ratregion
5031294PMC129043P12915109897364109897655Ratregion
5033877RH1404521655101169318101169483Ratregion
5028681RH80440895112513923112514012Ratregion
5031478AU0481911105100713273100713383Ratregion
5028927RH1428512445113046670113046914Ratregion
5031720AU0473711035101621882101621985Ratregion
5029379RH1445711595112416310112416469Ratregion
5032109RH94433975103020870103020967Ratregion
5032361AI12049013159982813699828474Ratregion
5032361AI12049013159982834399828474Ratregion
5027073D1S34192605112776883112777140Ratregion
5029705BI2902611225110218661110219469Ratregion
5035338BM3864221555102106356102106511Ratregion
5035410AI0076031925101505317101505509Ratregion
502786315.MMHAP53FRE9.seq2095101174343101174552Ratregion
5025424RH1282621915102623675102623875Ratregion
502793135.MMHAP28FLD5.seq1815109001682109001863Ratregion
5028029MHAa43g3.seq1055109077085109077190Ratregion
5030775AW5351851535104009899104010052Ratregion
5033567RH1392971715102402584102402755Ratregion
5028241D4Mit1541445111410443111410587Ratregion
5028243D4Mit1651825105829143105829325Ratregion
5033769RH1400532195101169322101169541Ratregion
5056839RH1446102065102284069102284275Ratregion
5057098D5Lev121055109721675109721780Ratregion
5057404AA9631301995112781625112781824Ratregion
5055315RH1437301525112570624112570776Ratregion
5058958BE1026141775112428800112428977Ratregion
505217916.MHAa96b4.seq1545105677047105677201Ratregion
5059062BI2783692145103917355103917568Ratregion
5053447RH1426542545101125772101126026Ratregion
5050786RH1342571955112337803112337996Ratregion
5052915RH1423471885109894384109894576Ratregion
5047482RH1323532135102224612102224827Ratregion
5047538RH1323851895111220079111220268Ratregion
5045572RH1312552035101375192101375395Ratregion
5047704RH1324801975102886291102886488Ratregion
5048222RH1327782175102889671102889888Ratregion
5047142RH1321571875113020904113021091Ratregion
5048372RH1328652125110960568110960780Ratregion
5042318RH1293652165101442257101442473Ratregion
5042444RH1294372085109913907109914116Ratregion
5042388RH1294052045101498022101498226Ratregion
5041180RH1287081995109563602109563801Ratregion
5075302RH1385162185109732963109733181Ratregion
5075366RH1385531205109666343109666463Ratregion
5076520RH1392232415102501070102501311Ratregion
5075550RH1386581965101369075101369271Ratregion
5076478RH1391981605102262097102262257Ratregion
5079796RH1412082095109783368109783577Ratregion
5078068RH1401252005103920046103920246Ratregion
5072876RH1371052015101442267101442468Ratregion
5072908RH1371231805109733610109733790Ratregion
5079352RH1409441815101114607101114788Ratregion
5071340RH1350261835110867751110867934Ratregion
5067534AU04768722459992333099923552Ratregion
5067706AU04758419659980089399801089Ratregion
5067706AU04758419659980093299801089Ratregion
5068230AU0472711755106940736106940911Ratregion
5068238AU0472662325111864527111864759Ratregion
5068536AU0470872665110570676110570941Ratregion
5060104AI0723721835109346692109346875Ratregion
5062258BE1064082015108230788108230989Ratregion
5063654BE1079192105100937532100937742Ratregion
5063724BF4047741805102581935102582115Ratregion
5062412BF3978971355104422245104422380Ratregion
5060756BF3890911615104410894104411055Ratregion
5062546BI2889681895112466595112466784Ratregion
5062790AW5344381645101118667101118831Ratregion
5061050AI1459521855111222023111222208Ratregion
5063096BE1071211545112781235112781389Ratregion
5066330PMC152658P33485109894800109895148Ratregion
5061504BE1119052085102326902102327110Ratregion
5063176BE1138492115101543131101543342Ratregion
5086991BE1068091635103627756103627919Ratregion
5082077BF4159481925101704072101704264Ratregion
5087516PMC26775P15865103021015103021601Ratregion
5087953Elavl41595105962376105962535Ratregion
5089617AU0492611405106205635106205775Ratregion
5090119AU0495612185104876010104876230Ratregion
5085012AI0095531155112230744112230859Ratregion
5082357BE1192431825103893165103893330Ratregion
5088597AU0486641995107732054107732259Ratregion
5090323AU0496832035101194455101194502Ratregion
5081246RH1420501875109787740109788718Ratregion
5081284RH1420722095101439761101439970Ratregion
5085916BM3851611545109948870109949024Ratregion
5085922BM3851741565112414467112414623Ratregion
5084616AA8507361905109428866109429056Ratregion
5084018AI2324231105109497180109497290Ratregion
5084024AI4075721155109894371109894486Ratregion
5503958UniSTS:2569462675109895884109896151Ratregion
5503680ELAVL2__75779485105962550105963498Ratregion
5503845Nmt12795103658564103658845Ratregion
5504010px-21e121355106315971106316106Ratregion
5504626PMC316663P32395104015134104015373Ratregion
5504336D11S27838205107370493107371313Ratregion
5506873G4707122259981947399819695Ratregion
5501179PMC152255P11485103991982103992130Ratregion
5501205PMC153970P11565109895405109895561Ratregion
5504698PMC55707P110055109895405109896410Ratregion
5505275Elavl24705105962786105963428Ratregion
5505275Elavl24705105962958105963428Ratregion
5502311RH1243872305101369255101369485Ratregion
Position Markers

Flank 1: (D5Rat151)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2599,753,548 - 99,753,708 (+)MAPPER
Rnor_6.05103,580,245 - 103,580,403NCBI
Rnor_5.05107,580,081 - 107,580,201NCBI
Rnor_5.05107,580,080 - 107,580,201NCBI
RGSC_v3.45104,231,741 - 104,231,900RGD
RGSC_v3.45104,231,742 - 104,231,900UniSTS
RGSC_v3.15104,236,968 - 104,237,126RGD
Celera598,259,651 - 98,259,809UniSTS
RH 3.4 Map5742.7UniSTS
RH 3.4 Map5742.7RGD
RH 2.0 Map5653.0RGD
Cytogenetic Map5q31UniSTS
Flank 2: (D5Rat25)
Rat AssemblyChrPosition (strand)Source
mRatBN7.25113,060,909 - 113,061,097 (+)MAPPER
Rnor_6.05117,037,089 - 117,037,276NCBI
Rnor_5.05120,979,996 - 120,980,183UniSTS
RGSC_v3.45118,805,535 - 118,805,723RGD
RGSC_v3.45118,805,536 - 118,805,723UniSTS
RGSC_v3.15118,810,762 - 118,810,949RGD
Celera5111,631,991 - 111,632,178UniSTS
RH 3.4 Map5789.6UniSTS
RH 3.4 Map5789.6RGD
SHRSP x BN Map561.5499UniSTS
SHRSP x BN Map561.5499RGD
Cytogenetic Map5q33UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)559793528113558156Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)564719390109719390Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)568984307104251008Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)568984307104251008Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)568984307104251008Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)579584860124584860Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)579584860124584860Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584132602129132602Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)590067849128034027Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)590067849128034027Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)597570330136479578Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)599016066119085810Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1600362Mcs19Mammary carcinoma susceptibility QTL 192.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)599485997103690167Rat
7394708Emca11Estrogen-induced mammary cancer QTL 11mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)599753548113061097Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
7794743Bp373Blood pressure QTL 3730.0058arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5112175546116047089Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general orthologous to 9p21 breast cancer locus in humans that was identified in the genome-wide studies 7364727
qtl_general measurement method: animals were examined for palpable mammary tumors 7 weeks after the E2 treatment, size and location was recorded; animals were killed when the tumors were ~2 cm 7364727
qtl_general inducing agent: 17beta-estradiol (E2) for 196 days 7364727