Bw122 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bw122 (Body weight QTL 122) Rattus norvegicus

Symbol: Bw122
Name: Body weight QTL 122
RGD ID: 737975
Previously known as: Niddm60; Non-insulin dependent diabetes mellitus QTL 60
Trait: body mass   (VT:0001259)    
Measurement Type: body weight   (CMO:0000012)    
LOD Score: 9.11
P Value: 0.005
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21258,843,780 - 260,122,809RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01280,850,604 - 282,365,384RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01288,207,586 - 289,700,417RGDRnor5.0
RGSC_v3.41266,234,605 - 267,593,558RGDRGSC3.4
RGSC_v3.11266,445,650 - 267,804,643RGD
Cross Type: Not Available
Strains Crossed: OLETF.BN-(D1Rat461-D1Rat459)/Got 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
obesity  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement
body weight  (IDA)

Experimental Condition

Measurement Method

Vertebrate Trait
body mass  (IDA)

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. A < 1.7 cM interval is responsible for Dmo1 obesity phenotypes in OLETF rats. Watanabe TK, etal., Clin Exp Pharmacol Physiol 2004 Jan;31(1-2):110-112.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1308538Rab11fip2RAB11 family interacting protein 21258950535259094555Rat
7609551LOC102556108uncharacterized LOC1025561081259283831259291744Rat
41054981Ndufab1-ps1NADH:ubiquinone oxidoreductase subunit AB1, pseudogene 11259294672259295761Rat
1305500Fam204afamily with sequence similarity 204, member A1259328551259366726Rat
41250872Trnap-agg88transfer RNA proline (anticodon AGG) 881259501726259501804Rat
71037Prlhrprolactin releasing hormone receptor1259606704259608391Rat
1308127Cacul1CDK2-associated, cullin domain 11259666335259726249Rat
2323620Snu13-ps5small nuclear ribonucleoprotein 13, pseudogene 51259716056259716928Rat
11433684LOC108349715uncharacterized LOC1083497151259740912259748207Rat
1308194Nanos1nanos C2HC-type zinc finger 11259897663259901561Rat
1307269Eif3aeukaryotic translation initiation factor 3, subunit A1259902767259932976Rat
41358313LOC120093054small nucleolar RNA SNORA191259917206259917337Rat
1308326Dennd10DENN domain containing 101259950955259974459Rat
1306088Sfxn4sideroflexin 41259976480259998778Rat
620040Prdx3peroxiredoxin 31260001642260014064Rat
61985Grk5G protein-coupled receptor kinase 51260028269260223699Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
35457D1Rat901481259647732259647894Ratregion
42550D1Rat4592081260122597260122809Ratregion
42553D1Rat4612371258843780258843987Ratregion
43455D1Got2712731259183872259184144Ratregion
43458D1Got2581501259385459259385609Ratregion
67792D1Uwm102081259900306259900476Ratregion
1639829D1Got3531731259472312259472485Ratregion
5038896RH1273951891260001900260002089Ratregion
5026236RH1314372041259976525259976729Ratregion
5034948AI2295091851259290332259290517Ratregion
5033397RH1386861361259974256259974392Ratregion
5031103BE1096821961259973238259973434Ratregion
5051607AW558126851259054309259054394Ratregion
5052361X846511991259908603259908802Ratregion
5057219D1Bda661391259606801259606940Ratregion
5057802BE1015771661259812363259812529Ratregion
5054769RH1434141011259338687259339269Ratregion
5040768RH1284721951259668623259668818Ratregion
5046312RH1316802101259603842259604052Ratregion
5074350RH1379661661259902256259902427Ratregion
5080596RH1416711821259339048259339230Ratregion
5075834RH1388241311259969638259970922Ratregion
5080002RH1413262191259903029259903248Ratregion
5079294RH1408982061259666491259666697Ratregion
5074602RH1381111201259010367259010487Ratregion
5067540AU0476831821259517985259518162Ratregion
5068018AU0473982261259449234259449264Ratregion
5068638AU0470242211260122572260122795Ratregion
5065974BE1163681531259665465259665618Ratregion
5088701AU0487252581259501469259501729Ratregion
5090465AU0497662311259098689259098920Ratregion
5503316UniSTS:2379881321259903266259903398Ratregion
5503939D19Mgc54641259054366259054830Ratregion
5504895ha310315911259714867259716458Ratregion
Position Markers

Flank 1: (D1Rat461)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21258,843,780 - 258,843,987 (+)MAPPER
Rnor_6.01280,850,604 - 280,850,810NCBI
Rnor_5.01288,207,586 - 288,207,792UniSTS
RGSC_v3.41266,234,606 - 266,234,812UniSTS
RGSC_v3.41266,234,605 - 266,234,810RGD
RGSC_v3.11266,445,650 - 266,445,855RGD
Celera1254,492,059 - 254,492,265UniSTS
RH 3.4 Map11697.9UniSTS
RH 3.4 Map11697.9RGD
RH 2.0 Map11322.8999RGD
SHRSP x BN Map1149.25RGD
Peak: (D1Rat90)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21259,647,732 - 259,647,894 (+)MAPPER
Rnor_6.01281,795,624 - 281,795,785NCBI
Rnor_5.01289,137,107 - 289,137,268UniSTS
RGSC_v3.41267,110,926 - 267,111,087UniSTS
RGSC_v3.41267,110,921 - 267,111,153RGD
RGSC_v3.11267,322,011 - 267,322,172RGD
Celera1255,291,309 - 255,291,470UniSTS
RH 3.4 Map11708.8RGD
RH 3.4 Map11708.8UniSTS
RH 2.0 Map11313.1999RGD
SHRSP x BN Map1148.15RGD
Flank 2: (D1Rat459)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21260,122,597 - 260,122,809 (+)MAPPER
Rnor_6.01282,365,175 - 282,365,384NCBI
Rnor_5.01289,700,208 - 289,700,417UniSTS
RGSC_v3.41267,593,348 - 267,593,558RGD
RGSC_v3.41267,593,349 - 267,593,558UniSTS
RGSC_v3.11267,804,434 - 267,804,643RGD
Celera1255,762,929 - 255,763,138UniSTS
RH 3.4 Map11704.5RGD
RH 3.4 Map11704.5UniSTS
RH 2.0 Map11311.7999RGD
SHRSP x BN Map1148.19RGD
Cytogenetic Map1q55UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
1549910Bw54Body weight QTL 540.05body mass (VT:0001259)body weight (CMO:0000012)1214647894259647894Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1214647894259647894Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1222363780260522016Rat
631690Scl5Serum cholesterol level QTL 52.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1236125214260522016Rat
71112Bw115Body weight QTL 11560.0001body mass (VT:0001259)body weight (CMO:0000012)1259647732260522016Rat
10053715Scort24Serum corticosterone level QTL 242.130.0088blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1221414816260522016Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
631837Niddm35Non-insulin dependent diabetes mellitus QTL 350.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1238699859259647894Rat
631836Stl31Serum triglyceride level QTL 314.645e-06blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1237147813260522016Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
1300108Rf8Renal function QTL 83.75renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1228581588259647894Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1224054293260122809Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1225126575260522016Rat
7387289Uae45Urinary albumin excretion QTL 452.860.0021urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1223262787260522016Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1224054293260122809Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1221264111259647894Rat
1581544Rf52Renal function QTL 520.05urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)1232156370259647894Rat
631536Lnnr2Liver neoplastic nodule remodeling QTL 22.90.0005liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)1233948574260522016Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1224569538260122809Rat
734768Niddm59Non-insulin dependent diabetes mellitus QTL 59body mass (VT:0001259)body weight (CMO:0000012)1213843987258843987Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1216255568260522016Rat
737975Bw122Body weight QTL 1229.110.005body mass (VT:0001259)body weight (CMO:0000012)1258843780260122809Rat
1358890Bp259Blood pressure QTL 2593.06arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1210702053260522016Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Niddm60


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-03-21 Bw122  Body weight QTL 122  Niddm60  Non-insulin dependent diabetes mellitus QTL 60  Name updated 68913 APPROVED
2013-03-21 Bw122  Body weight QTL 122  Niddm60  Non-insulin dependent diabetes mellitus QTL 60  Symbol updated 68687 APPROVED

RGD Curation Notes
Note Type Note Reference
qtl_gene length of QTL region was 1.7 cM 737696