Niddm55 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Niddm55 (Non-insulin dependent diabetes mellitus QTL 55) Rattus norvegicus

Symbol: Niddm55
Name: Non-insulin dependent diabetes mellitus QTL 55
RGD ID: 724548
Previously known as: Nidd18/of
Trait: blood glucose amount   (VT:0000188)    
Measurement Type: blood glucose level area under curve (AUC)   (CMO:0000350)    
LOD Score: Not Available
P Value: 0.02
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21568,327,360 - 73,699,069RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01575,761,216 - 81,263,843RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01579,317,715 - 84,802,815RGDRnor5.0
RGSC_v3.41574,779,895 - 80,370,512RGDRGSC3.4
RGSC_v3.11574,795,675 - 80,386,293RGD
Cross Type: intercross
Strains Crossed: F344/DuCrlCrlj OLETF/Got 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Identification of epistatic interactions involved in non-insulin-dependent diabetes mellitus in the Otsuka Long-Evans Tokushima Fatty rat. Yamada T, etal., Exp Anim 2001 Apr;50(2):115-23.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
41023740LOC120097057uncharacterized LOC120097057156848083468606048Rat
41287184LOC120097257small nucleolar RNA SNORA17156867010768670234Rat
41204718LOC120097281U2 spliceosomal RNA156877186068772017Rat
1306348Pcdh9protocadherin 9156934010870237531Rat
41027949LOC120097302U1 spliceosomal RNA156946362569463786Rat
41051620LOC120097140uncharacterized LOC120097140156950797869538198Rat
40957543LOC120097141uncharacterized LOC120097141156968199469719442Rat
41257981LOC120097142uncharacterized LOC120097142156999016870006898Rat
1595676Vdac1-ps13voltage-dependent anion channel 1, pseudogene 13157047334670479101Rat
41023963Snrk-ps1SNF related kinase, pseudogene 1157078688370789325Rat
41251075LOC120097271small nucleolar RNA SNORA17157083639770836536Rat
11410099LOC108353042uncharacterized LOC108353042157086763970872983Rat
1592146Ngrn-ps3neugrin, neurite outgrowth associated, pseudogene 3157145020371453611Rat
41054013LOC120097265small nucleolar RNA SNORA17157166663371666721Rat
41176091LOC120097266small nucleolar RNA SNORA17157169596971696057Rat
41121265LOC120097225small nucleolar RNA SNORA2/SNORA34 family157176224671762373Rat
1592145Sinhcaf-ps1SIN3-HDAC complex associated factor, pseudogene 1157231631972318425Rat
9417610LOC103693758uncharacterized LOC103693758157231848772385670Rat
1306441Spertlspermatid associated like157246415772468708Rat
7607858Afg3l1-ps1AFG3 (ATPase family gene 3)-like 1, pseudogene 1157251057272511658Rat
2321672Akip1-ps1A-kinase interacting protein 1, pseudogene 1157257613772579688Rat
1307452Klhl1kelch-like family member 1157269818873142707Rat
41261712LOC120097292U6 spliceosomal RNA157300867373008779Rat
2321527LOC100360731SNRPN upstream reading frame protein-like157319322273193407Rat
1592111LOC290428similar to small nuclear ribonucleoparticle-associated protein157319364773194285Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
34222D15Mgh8139157369051873690657Ratregion
35230D15Rat22164157369906973699215Ratregion
36663D15Rat21159156832716568327360Ratregion
39524D15Rat98146157369906973699205Ratregion
41332D15Rat94171156962579369625966Ratregion
40882D15Rat97224157147706771477291Ratregion
45595D18Got3281157126847471270091Ratregion
1631898D15Got228144157237680472376943Ratregion
1635632D15Got21177156954542869545505Ratregion
1634050D15Got213116157196046571960581Ratregion
5038878RH127385200157145368971453882Ratregion
7206534UniSTS:546922999156934024769341246Ratregion
5037005AU049892298156862226168622559Ratregion
5035649RH45841138156934041069340548Ratregion
5029729BE102165149156989884869898997Ratregion
5058976BE102662172156970588969706061Ratregion
5074298RH137936146157021274870212894Ratregion
5089143AU048980150157338924573389395Ratregion
5088447AU048574199156876430068764499Ratregion
5090511AU049794215157261218272612397Ratregion
5089027AU048911125157237684172376966Ratregion
5083019BF390670197156991371269913909Ratregion
5500873D8S18071641157324127173242912Ratregion
Position Markers

Flank 1: (D15Rat22)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21573,699,069 - 73,699,215 (+)MAPPER
Rnor_6.01581,263,843 - 81,263,988NCBI
Rnor_5.01584,802,815 - 84,802,960UniSTS
RGSC_v3.41580,370,512 - 80,370,658RGD
RGSC_v3.41580,370,513 - 80,370,658UniSTS
RGSC_v3.11580,386,293 - 80,386,438RGD
Celera1572,968,417 - 72,968,562UniSTS
RH 3.4 Map15521.0UniSTS
RH 3.4 Map15521.0RGD
RH 2.0 Map15385.2RGD
SHRSP x BN Map1543.6598RGD
Cytogenetic Map15 RGD
Flank 2: (D15Rat21)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21568,327,165 - 68,327,360 (+)MAPPER
Rnor_6.01575,761,024 - 75,761,216NCBI
Rnor_5.01579,317,523 - 79,317,715UniSTS
RGSC_v3.41574,779,702 - 74,779,895RGD
RGSC_v3.41574,779,703 - 74,779,895UniSTS
RGSC_v3.11574,795,482 - 74,795,675RGD
Celera1567,733,051 - 67,733,242UniSTS
RH 2.0 Map4619.2RGD
SHRSP x BN Map1541.3898RGD
FHH x ACI Map1557.06RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat
724545Niddm54Non-insulin dependent diabetes mellitus QTL 540.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)155079449473699215Rat
2317050Aia24Adjuvant induced arthritis QTL 242.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)155284790873690657Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)155380615298806152Rat
61477Aia4Adjuvant induced arthritis QTL 43joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)155559608991365858Rat
631516Gluco31Glucose level QTL 317blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)155559608995018120Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1558156477101769107Rat
2313080Bss65Bone structure and strength QTL 653.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)156099046873690657Rat
731177Uae26Urinary albumin excretion QTL 262.40.025urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1567588667101769107Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1568327165100062518Rat
724548Niddm55Non-insulin dependent diabetes mellitus QTL 550.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)156832736073699069Rat
1331724Bp223Blood pressure QTL 2233.53715arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)157369051895018228Rat
1641889Colcr6Colorectal carcinoma resistance QTL 62.90.0126intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)157369051899794247Rat
70182BpQTLcluster12Blood pressure QTL cluster 123.53arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)157369065795018120Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Niddm55

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general markers are 18.6 cM apart; involved in epistatic interaction with Niddm 53 619670