Niddm54 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Niddm54 (Non-insulin dependent diabetes mellitus QTL 54) Rattus norvegicus

Symbol: Niddm54
Name: Non-insulin dependent diabetes mellitus QTL 54
RGD ID: 724545
Previously known as: Nidd17/of
Trait: blood glucose amount   (VT:0000188)    
Measurement Type: blood glucose level area under curve (AUC)   (CMO:0000350)    
LOD Score: Not Available
P Value: 0.02
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81557,203,895 - 80,107,161RGD_MAPPER_PIPELINE
mRatBN7.21550,794,494 - 73,699,215RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01557,528,970 - 81,263,988RGD_MAPPER_PIPELINERnor_6.0
Rnor_5.01561,238,603 - 84,802,960RGDRnor_5.0
RGSC_v3.41556,346,569 - 80,370,658RGDRGSC_v3.4
RGSC_v3.11556,362,349 - 80,386,438RGD
Cross Type: intercross
Strains Crossed: F344/DuCrlCrlj OLETF/Got 



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Identification of epistatic interactions involved in non-insulin-dependent diabetes mellitus in the Otsuka Long-Evans Tokushima Fatty rat. Yamada T, etal., Exp Anim 2001 Apr;50(2):115-23.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1592168Siah3siah E3 ubiquitin protein ligase family member 3155718024557247608Rat
41398796LOC120097040uncharacterized LOC120097040155723084257258766Rat
1561044Cby2chibby family member 2155731882057413687Rat
6491099Erich6bglutamate-rich 6B155738450957423543Rat
1304555Cog3component of oligomeric golgi complex 3155738999457480454Rat
1592167Gabarapl2-ps2GABA type A receptor associated protein like 2, pseudogene 2155739490357395921Rat
1359702Slc25a30solute carrier family 25, member 30155748634657508981Rat
7699265LOC102552389uncharacterized LOC102552389155755284857558036Rat
621623Tpt1tumor protein, translationally-controlled 1155756221757568968Rat
41070333Snora31small nucleolar RNA, H/ACA box 31155756856457568693Rat
7695025LOC102549099uncharacterized LOC102549099155758544657602118Rat
40992298LOC12009704340S ribosomal protein S29-like155760806357642143Rat
620772Gtf2f2general transcription factor IIF subunit 2155761536157736477Rat
1594637Kctd4potassium channel tetramerization domain containing 4155767502457686816Rat
40942556LOC120097218small nucleolar RNA SNORA5155769339557693534Rat
402433757LOC134482153uncharacterized LOC134482153155775761757759116Rat
40964313LOC120097044uncharacterized LOC120097044155775985857773667Rat
9082307LOC103690313uncharacterized LOC103690313155776940157771226Rat
1307254Gpalpp1GPALPP motifs containing 1155781849057838723Rat
41169285Ran-ps6RAN, member RAS oncogene family, pseudogene 6155782507357825903Rat
1359440Nufip1nuclear FMR1 interacting protein 1155783886457869597Rat
9173655Hmga1-ps3high mobility group AT-hook 1, pseudogene 3155786975057871415Rat
402390731LOC134482154uncharacterized LOC134482154155788149457887527Rat
402424156LOC134482155uncharacterized LOC134482155155788149458056713Rat
11450795Trnae-uuc7transfer RNA glutamic acid (anticodon UUC) 7155789467357894744Rat
41109740LOC120097047uncharacterized LOC120097047155790779757922172Rat
402162172LOC134481992uncharacterized LOC134481992155794495657946028Rat
11484738LOC108352943uncharacterized LOC108352943155794604257969446Rat
402122455LOC134481991uncharacterized LOC134481991155795182457954875Rat
41059337LOC120097108uncharacterized LOC120097108155795516157976080Rat
41148120LOC120097109uncharacterized LOC120097109155797648457980448Rat
41309137Rps29-ps6ribosomal protein S29, pseudogene 6155808550958089333Rat
3850Tsc22d1TSC22 domain family, member 1155815961258260244Rat
41059573LOC120097112uncharacterized LOC120097112155823040358231831Rat
1566076Serp2stress-associated endoplasmic reticulum protein family member 2155828914858313224Rat
41348002LOC120097114uncharacterized LOC120097114155831345058314029Rat
7631267LOC102556319uncharacterized LOC102556319155832650858338622Rat
9094045LOC103693719uncharacterized LOC103693719155842731558436831Rat
402182025LOC134482156uncharacterized LOC134482156155843898158446452Rat
7700048LOC102546462uncharacterized LOC102546462155846965858679227Rat
402259111LOC134482157uncharacterized LOC134482157155849595058547941Rat
11507603LOC108352946uncharacterized LOC108352946155851720158523338Rat
1310185Lacc1laccase domain containing 1155879947758816840Rat
2321506Ccdc122coiled-coil domain containing 122155881692758899200Rat
41029888LOC120097048uncharacterized LOC120097048155890168158913189Rat
1306118Enox1ecto-NOX disulfide-thiol exchanger 1155892451959488919Rat
41087576Rps15-ps5ribosomal protein S15, pseudogene 5155903382259034349Rat
40986166Trnap-ugg7transfer RNA proline (anticodon UGG) 7155913839059138470Rat
41101550LOC120097117uncharacterized LOC120097117155936828359369967Rat
1307154Dnajc15DnaJ heat shock protein family (Hsp40) member C15155959431459658862Rat
1563207Epsti1epithelial stromal interaction 1155969271259791376Rat
1560137Fam216bfamily with sequence similarity 216, member B155987866559905887Rat
620784Tnfsf11TNF superfamily member 11156008300860114479Rat
7661800LOC102549816uncharacterized LOC102549816156026722560285697Rat
2079Akap11A-kinase anchoring protein 11156032083960365480Rat
41164845LOC120097049uncharacterized LOC120097049156036535760369998Rat
1561955Dgkhdiacylglycerol kinase, eta156039027960559777Rat
11447237LOC108353040uncharacterized LOC108353040156064125860644985Rat
1308772Vwa8von Willebrand factor A domain containing 8156066176460985971Rat
41277989LOC120097120uncharacterized LOC120097120156066317860678672Rat
41000723LOC120097121uncharacterized LOC120097121156069454160705783Rat
41003131Hars1-ps1histidyl-tRNA synthetase 1, pseudogene 1156081571860826062Rat
402413577LOC134482158uncharacterized LOC134482158156097057060972330Rat
619721Rgccregulator of cell cycle156107157461084408Rat
6501536Glul-ps1glutamate-ammonia ligase, pseudogene 1156111149761113937Rat
1584324Naa16N(alpha)-acetyltransferase 16, NatA auxiliary subunit156112070461179979Rat
41033512LOC120097256U2 spliceosomal RNA156117910261179264Rat
1584329Mtrf1mitochondrial translation release factor 1156118595861213783Rat
6501695Kbtbd7kelch repeat and BTB domain containing 7156121595761220536Rat
1584320Rps24-ps14ribosomal protein S24, pseudogene 14156122526561225750Rat
6501416Rpl15-ps1ribosomal protein L15, pseudogene 1156123232661232944Rat
1305086Kbtbd6kelch repeat and BTB domain containing 6156125736061259117Rat
620033Wbp4WW domain binding protein 4156127177461299740Rat
402170861LOC134481995uncharacterized LOC134481995156127918561298193Rat
11379973Trnae-uuc8transfer RNA glutamic acid (anticodon UUC) 8156129988161299952Rat
402229851LOC134481993microfibrillar-associated protein 1-like156134139161374630Rat
620697Elf1E74 like ETS transcription factor 1156135402661395762Rat
1307550Sugt1SGT1 homolog, MIS12 kinetochore complex assembly cochaperone156140047861441303Rat
620176Cnmdchondromodulin156145061761475382Rat
2325470Mir759microRNA 759156155107361551169Rat
69350Pcdh8protocadherin 8156160752161612090Rat
11434381LOC108352947uncharacterized LOC108352947156165863661695608Rat
1311708Olfm4olfactomedin 4156179088961838773Rat
1564564Rpl14l1ribosomal protein L14 like 1156192940461940951Rat
9685073Mir1297microRNA 1297156325743163257504Rat
1592156Sord-ps6sorbitol dehydrogenase, pseudogene 6156353716163538214Rat
2320681LOC10036118040S ribosomal protein S17-like156358589463587992Rat
11436659LOC108353006ATP synthase subunit d, mitochondrial pseudogene156361952763620779Rat
7672387LOC102554138uncharacterized LOC102554138156447541564493365Rat
1597679Calm2-ps2calmodulin 2, pseudogene 2156451953764520655Rat
9466192Uqcrbl2ubiquinol-cytochrome c reductase binding protein like 2156516828565168608Rat
41086981LOC120097308U6 spliceosomal RNA156524895865249060Rat
40958512LOC120097052uncharacterized LOC120097052156530348465370221Rat
402433984LOC134481996protein kish-A-like156535570865356457Rat
402439121LOC134481997uncharacterized LOC134481997156541932465424197Rat
41262856LOC120097242small nucleolar RNA SNORA17156547652465476655Rat
40975150LOC120097286small nucleolar RNA U3156595673065956922Rat
1304753Pcdh17protocadherin 17156663154966725007Rat
11379167LOC108352949uncharacterized LOC108352949156664613366664498Rat
41315464LOC120097053uncharacterized LOC120097053156778929067802993Rat
40989554LOC120097194U6 spliceosomal RNA156860071268600801Rat
1593287Diaph3diaphanous-related formin 3156895199269421623Rat
402300370LOC134481998uncharacterized LOC134481998156906530169158676Rat
41002785Trnav-aac40transfer RNA valine (anticodon AAC) 40156911613669116217Rat
402213913LOC134481999uncharacterized LOC134481999156927982269285797Rat
41189376LOC120097230small nucleolar RNA SNORA48156945903869459178Rat
41127910Atp5mj-ps2ATP synthase membrane subunit j, pseudogene 2156961064869611065Rat
2320163Mfap1a-ps2microfibrillar-associated protein 1A, pseudogene 2156968431869684914Rat
1310126Tdrd3tudor domain containing 3156974875469911605Rat
402251051LOC134482000uncharacterized LOC134482000156994704769983609Rat
41326155LOC120097228small nucleolar RNA SNORA48157007727570077418Rat
41026458LOC120097310U6 spliceosomal RNA157015354770153653Rat
41096054LOC120093128uncharacterized LOC120093128157034527870349807Rat
6496491Rpsa-ps1ribosomal protein SA, pseudogene 1157035742170358408Rat
41381972Tubal-ps1tubulin, alpha like, pseudogene 1157047974270480957Rat
1592113Pkm-ps18pyruvate kinase M1/2, pseudogene 18157072846270730064Rat
1306297Pcdh20protocadherin 20157083404270840298Rat
2320118Mtfr2-ps1mitochondrial fission regulator 2, pseudogene 1157183538571836380Rat
41365783LOC120097247small nucleolar RNA SNORA17157215937772159508Rat
1592151Phgdh-ps4phosphoglycerate dehydrogenase, pseudogene 4157221428972215821Rat
40959529LOC120097187uncharacterized LOC120097187157290747172928978Rat
41226654LOC120097232small nucleolar RNA SNORA17157291941272919543Rat
41325790LOC120097252small nucleolar RNA SNORA17157296024472960374Rat
7552264LOC102547864uncharacterized LOC102547864157296070972998346Rat
40983884LOC120097054uncharacterized LOC120097054157306017173076041Rat
7554821Envl-ps1MLV-related proviral Env polyprotein-like, pseudogene 1157314560473166249Rat
7651565LOC102546653uncharacterized LOC102546653157327282173285191Rat
41079966LOC120097254small nucleolar RNA SNORA17157369719973697328Rat
2319690Cdk4-ps1cyclin-dependent kinase 4, pseudogene 1157377946473780021Rat
1595677Nono-ps9non-POU domain containing, octamer-binding, pseudogene 9157379605573844224Rat
41018907LOC120097188uncharacterized LOC120097188157388600173900207Rat
1590791Rplp2l2ribosomal protein lateral stalk subunit P2 like 2157404677274047261Rat
40995928LOC120097056uncharacterized LOC120097056157427125974362669Rat
41023740LOC120097057uncharacterized LOC120097057157488922575013903Rat
41287184LOC120097257small nucleolar RNA SNORA17157507849075078617Rat
41204718LOC120097281U2 spliceosomal RNA157518024175180398Rat
1306348Pcdh9protocadherin 9157574847276646644Rat
41027949LOC120097302U1 spliceosomal RNA157587198375872144Rat
41051620LOC120097140uncharacterized LOC120097140157591633575959590Rat
1306348Pcdh9protocadherin 9157607802476127778Rat
1595676Vdac1-ps13voltage-dependent anion channel 1, pseudogene 13157688162876887383Rat
41023963Snrk-ps1SNF related kinase, pseudogene 1157719527577197322Rat
41251075LOC120097271small nucleolar RNA SNORA17157724467277244811Rat
11410099LOC108353042uncharacterized LOC108353042157727591277281256Rat
1592146Ngrn-ps3neugrin, neurite outgrowth associated, pseudogene 3157785845777861865Rat
41054013LOC120097265small nucleolar RNA SNORA17157807487678074964Rat
41121265LOC120097225small nucleolar RNA SNORA2/SNORA34 family157817031778170444Rat
1592145Sinhcaf-ps1SIN3-HDAC complex associated factor, pseudogene 1157872436978725935Rat
9417610LOC103693758uncharacterized LOC103693758157872652278793711Rat
1306441Golga6l9golgin A6 family like 9157887217778876741Rat
7607858Afg3l1-ps1AFG3 (ATPase family gene 3)-like 1, pseudogene 1157891860578919691Rat
2321672Akip1-ps1A-kinase interacting protein 1, pseudogene 1157898412678984766Rat
1307452Klhl1kelch-like family member 1157910616479550684Rat
41261712LOC120097292U6 spliceosomal RNA157941663979416745Rat
1559682Ppial4gpeptidylprolyl isomerase A like 4G157960112880424184Rat
2321527LOC100360731SNRPN upstream reading frame protein-like157960119379601417Rat
1592111Snrpnl2small nuclear ribonucleoprotein polypeptide N like 2157960159179602281Rat
402017540LOC134481994uncharacterized LOC134481994156142184061430762Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
33868D15Mit7225155847086058471085Ratregion
37276D15Rat68140156289343462893574Ratregion
35230D15Rat22146158010701580107161Ratregion
35362D15Rat19156155720389557204051Ratregion
37620D15Rat74181155901798859018169Ratregion
37696D15Rat59224156437353264373756Ratregion
37794D15Rat48206156171095161711157Ratregion
37918D15Rat39242156172479561725037Ratregion
36528D15Rat36173156029724160297414Ratregion
36576D15Rat18146155819776158197907Ratregion
36663D15Rat21193157473556474735757Ratregion
40554D15Rat93171156296306762963238Ratregion
39192D15Rat47208157285156572851773Ratregion
39524D15Rat98136158010701580107151Ratregion
42006D15Arb2230156739913767399367Ratregion
43051D15Rat146202155722915157229353Ratregion
43052D15Rat14899155763874957638848Ratregion
43054D15Rat150211156899091468991125Ratregion
42407D15Rat151227157487904574879272Ratregion
41010D15Rat96173157161424571614418Ratregion
41636D15Rat123137155925708759257224Ratregion
41804D15Rat121106155862611758626223Ratregion
45274D15Got72209156600405866004267Ratregion
45275D15Got60194155721341457213608Ratregion
60115D15Got68280156157579961576079Ratregion
66545D15Mco15166156297326262973428Ratregion
1631898D15Got228139157878484378784982Ratregion
1629889D15Got22291157050740070507491Ratregion
1640782D15Got243139156891922768919366Ratregion
1638310D15Got207137156288822462888361Ratregion
5038840RH127363689156112185961122548Ratregion
5031670AU047541214157261368472613898Ratregion
5029707BE096152170155881554158815711Ratregion
5032627RH134704272156098564860985920Ratregion
5051146RH134466179155781866557818844Ratregion
5059692BE097649349155843642958436778Ratregion
5067952AU047438129156633750966337638Ratregion
5069356AU046551268155738982957390097Ratregion
5065504BE109148207156039633560396542Ratregion
5502774LOC144997108156672283366722941Ratregion
152025251rs81501320156032105160321051Ratregion
Position Markers

Flank 1: (D15Rat19)
Rat AssemblyChrPosition (strand)Source
GRCr81557,203,895 - 57,204,051 (+)Marker Load Pipeline
mRatBN7.21550,794,494 - 50,794,652 (+)MAPPER
Rnor_6.01557,528,970 - 57,529,125NCBI
Rnor_5.01561,238,603 - 61,238,758UniSTS
RGSC_v3.41556,346,569 - 56,346,725RGD
RGSC_v3.41556,346,570 - 56,346,725UniSTS
Celera1550,425,266 - 50,425,421UniSTS
RGSC_v3.11556,362,349 - 56,362,505RGD
SHRSP x BN Map1534.6299UniSTS
SHRSP x BN Map1534.6299RGD
FHH x ACI Map1547.47RGD
Cytogenetic Map15q11UniSTS
Flank 2: (D15Rat22)
Rat AssemblyChrPosition (strand)Source
GRCr81580,107,015 - 80,107,161 (+)Marker Load Pipeline
mRatBN7.21573,699,069 - 73,699,215 (+)MAPPER
Rnor_6.01581,263,843 - 81,263,988NCBI
Rnor_5.01584,802,815 - 84,802,960UniSTS
RGSC_v3.41580,370,512 - 80,370,658RGD
RGSC_v3.41580,370,513 - 80,370,658UniSTS
Celera1572,968,417 - 72,968,562UniSTS
RGSC_v3.11580,386,293 - 80,386,438RGD
RH 3.4 Map15521.0UniSTS
RH 3.4 Map15521.0RGD
RH 2.0 Map15385.2RGD
SHRSP x BN Map1543.6598RGD
Cytogenetic Map15 RGD


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1574735564106469153Rat
724545Niddm54Non-insulin dependent diabetes mellitus QTL 540.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)155720389580107161Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)154367724488677244Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
724548Niddm55Non-insulin dependent diabetes mellitus QTL 550.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)157473575780107015Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631516Gluco31Glucose level QTL 317blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1572716871101425383Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)1561710951106710951Rat
1331724Bp223Blood pressure QTL 2233.53715arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1575928947101425383Rat
2317050Aia24Adjuvant induced arthritis QTL 242.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1559257087104257087Rat
2313080Bss65Bone structure and strength QTL 653.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)1567399137108192169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)154367724488677244Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1544806773104695021Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)1560213984105213984Rat
61477Aia4Adjuvant induced arthritis QTL 43joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)156244089297773284Rat
70182BpQTLcluster12Blood pressure QTL cluster 123.53arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)1572716871101425383Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1564571127108192169Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)154046315285463152Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)154367724488677244Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Niddm54

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general markers are 17.1 cM apart; have epistatic interaction with Niddm 52 619670