Bp358 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp358 (Blood pressure QTL 358) Rattus norvegicus

Symbol: Bp358
Name: Blood pressure QTL 358
RGD ID: 7204484
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: mean arterial blood pressure   (CMO:0000009)    
LOD Score: Not Available
P Value: 0.001
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21213,008,296 - 19,212,979RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01215,085,585 - 22,283,507RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01217,102,817 - 24,300,160RGDRnor5.0
Cross Type: Not Available
Strains Crossed: SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
Albuminuria  (IAGP)
hypertension  (IAGP)
proteinuria  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Identification of hypertension susceptibility loci on rat chromosome 12. Flister MJ, etal., Hypertension. 2012 Oct;60(4):942-8. doi: 10.1161/HYPERTENSIONAHA.112.198200. Epub 2012 Aug 6.
2. Vascular dysfunction precedes hypertension associated with a blood pressure locus on rat chromosome 12. Prisco SZ, etal., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22.
3. Refined Mapping of a Hypertension Susceptibility Locus on Rat Chromosome 12. Prisco SZ, etal., Hypertension. 2014 Jul 7. pii: HYPERTENSIONAHA.114.03550.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1560686Sdk1sidekick cell adhesion molecule 1121237807413363934Rat
41240022LOC120096102U6 spliceosomal RNA121303886713038969Rat
1584808Nip7-ps9nucleolar pre-rRNA processing protein NIP7, pseudogene 9121342089613421417Rat
41079527LOC120095893uncharacterized LOC120095893121343303013460245Rat
7598302LOC102547234uncharacterized LOC102547234121354778913607490Rat
41014784LOC120095894uncharacterized LOC120095894121358920213594498Rat
2323211Card11caspase recruitment domain family, member 11121362114013758115Rat
71018Gna12G protein subunit alpha 12121380558013886255Rat
1311314Amz1archaelysin family metallopeptidase 1121388651813924275Rat
1565146Brat1BRCA1-associated ATM activator 1121392888913951760Rat
1311349IqceIQ motif containing E121394329013982708Rat
1309549Ttyh3tweety family member 3121399683114025457Rat
620587LfngLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase121403055114038996Rat
71055Grifingalectin-related inter-fiber protein121408017014082892Rat
1308214Chst12carbohydrate sulfotransferase 12121411063114129099Rat
1598146Kif19bkinesin family member 19B121414416314196259Rat
41188349LOC120095895uncharacterized LOC120095895121414908814152690Rat
41182922LOC120096093U6 spliceosomal RNA121416998914170094Rat
1309018Eif3beukaryotic translation initiation factor 3, subunit B121419640314220865Rat
11502171LOC108352425uncharacterized LOC108352425121422308014265458Rat
1305791Snx8sorting nexin 8121425182914300435Rat
621080Nudt1nudix hydrolase 1121430251414309559Rat
1305944Mrm2mitochondrial rRNA methyltransferase 2121430955614314759Rat
1596881Mad1l1mitotic arrest deficient 1 like 1121432089214630750Rat
1308787Elfn1extracellular leucine-rich repeat and fibronectin type III domain containing 1121466004914725709Rat
2319950Psmg3proteasome assembly chaperone 3121480944014812357Rat
1306702Tmem184atransmembrane protein 184A121481750814833109Rat
628633MafkMAF bZIP transcription factor K121483462814856414Rat
7519900LOC102546414uncharacterized LOC102546414121484552214848118Rat
1308908Ints1integrator complex subunit 1121486131214886048Rat
1307875Micall2MICAL-like 2121489918814927949Rat
69361UncxUNC homeobox121509277915097300Rat
11414185Npm1-ps12nucleophosmin 1, pseudogene 12121513561915136849Rat
1310991Zfand2azinc finger AN1-type containing 2A121516160115172679Rat
1566418C12h7orf50similar to human chromosome 7 open reading frame 50121518572815289042Rat
619845Gper1G protein-coupled estrogen receptor 1121521721715222679Rat
7673409C130050O18RiklRIKEN cDNA C130050O18 gene like121522974315241457Rat
1560731Gpr146G protein-coupled receptor 146121525193615267217Rat
2325466Mir339microRNA 339121527754615277641Rat
1305193Cyp2w1cytochrome P450, family 2, subfamily w, polypeptide 1121529155215296421Rat
1305631Cox19cytochrome c oxidase assembly factor COX19121530353515313014Rat
621418Adap1ArfGAP with dual PH domains 1121532391315376110Rat
1311660Get4guided entry of tail-anchored proteins factor 4121537700915394238Rat
1359142Sun1Sad1 and UNC84 domain containing 1121539637815441277Rat
7682710LOC102547493uncharacterized LOC102547493121543065715453779Rat
1566028Dnaaf5dynein, axonemal, assembly factor 5121545363615492722Rat
3392Prkar1bprotein kinase cAMP-dependent type I regulatory subunit beta121549223315624942Rat
9133748LOC103691050uncharacterized LOC103691050121563246015636507Rat
3282Pdgfaplatelet derived growth factor subunit A121564554915667056Rat
7536442LOC10254879440S ribosomal protein S27-like121577683915778793Rat
1594158Foxl3forkhead box L3121581217715814534Rat
1311980Fam20cFAM20C, golgi associated secretory pathway kinase121582686415885423Rat
41016460Ppp1r14b-ps2protein phosphatase 1, regulatory (inhibitor) subunit 14B, pseudogene121589313815975566Rat
1566386Znf846zinc finger protein 846121597931216012933Rat
1310463Zfp68zinc finger protein 68121602605816040995Rat
1562569Rps8-ps9ribosomal protein S8, pseudogene 9121604777616048497Rat
1625997Vom2r-ps98vomeronasal 2 receptor, pseudogene 98121606460616066575Rat
41315690Spn-ps4sialophorin, pseudogene 4121609028116097302Rat
6499499Spn-ps1sialophorin, pseudogene 1121610035416101498Rat
1598204Spn-ps7sialophorin, pseudogene 7121610570516106765Rat
6499303Spn-ps2sialophorin, pseudogene 2121611083816112028Rat
2319349Spn-ps6sialophorin, pseudogene 6121611083816117345Rat
1559964Spnl2sialophorin like 2121612615016131108Rat
1598202Spn-ps8sialophorin, pseudogene 8121613127516133558Rat
1359506Spnl1sialophorin like 1121613658316147719Rat
41150475Spn-ps5sialophorin, pseudogene 5121614788516150072Rat
6497070Spn-ps3sialophorin, pseudogene 3121615474016156686Rat
1591744Auts2l1autism susceptibility candidate 2 like 1121619607116233257Rat
1359435Zfp157zinc finger protein 157121624823016279459Rat
1332710Or7a43-ps1olfactory receptor family 7 subfamily A member 43, pseudogene 1121628844616289236Rat
1305017Dhrsxdehydrogenase/reductase X-linked121629976816304553Rat
708472Asmtacetylserotonin O-methyltransferase121630471916309568Rat
1564640Akap17aA-kinase anchoring protein 17A121631042716315166Rat
1306877Asmtlacetylserotonin O-methyltransferase-like121631533516318083Rat
628728Il3rainterleukin 3 receptor subunit alpha121631808116323781Rat
1560288Pum3-ps3pumilio RNA-binding family member 3, pseudogene 3121635713116359221Rat
1595919Cyp3a62cytochrome P450, family 3, subfamily a, polypeptide 62121639799816433833Rat
7641109LOC102554019uncharacterized LOC102554019121642643916479103Rat
7612525LOC102554070uncharacterized LOC102554070121656636616569183Rat
41378758Fus-ps5FUS RNA binding protein, pseudogene 5121657167116577185Rat
1593752Tubb4b-ps2tubulin, beta 4B class IVb, pseudogene 2121661134416612890Rat
1584948Cbwd1-ps2COBW domain containing 1, pseudogene 2121662616216629000Rat
1562172Spry3sprouty RTK signaling antagonist 3121666318816673124Rat
621558Vamp7vesicle-associated membrane protein 7121672848616764261Rat
708392Cyp3a9cytochrome P450, family 3, subfamily a, polypeptide 9121680622216846428Rat
1595709LOC498158hypothetical LOC498158121686689516867939Rat
2319106Rpl31l4ribosomal protein L31-like 4121689311116893551Rat
727930Gjc3gap junction protein, gamma 3121689984616912309Rat
7581366Ccdc90b-ps1coiled-coil domain containing 90B, pseudogene 1121690674816908225Rat
2187Azgp1alpha-2-glycoprotein 1, zinc-binding121693099016939333Rat
41111819Rpl34-ps3ribosomal protein L34, pseudogene 3121696413416964559Rat
1560616Zkscan1zinc finger with KRAB and SCAN domains 1121696628716987680Rat
41041701LOC120095841uncharacterized LOC120095841121697612216995839Rat
9368177Elocl1elongin C like 1121698971716991140Rat
1309981Zscan21zinc finger and SCAN domain containing 21121699849617024167Rat
9205257LOC103691091NHP2-like protein 1 pseudogene121701804017019347Rat
6489147Zfp113zinc finger protein 3121702210417033776Rat
1309919Cops6COP9 signalosome subunit 6121703897917041818Rat
1303018Mcm7minichromosome maintenance complex component 7121704220717049470Rat
2325594Mir25microRNA 25121704293217043015Rat
2325459Mir93microRNA 93121704313517043221Rat
2325388Mir106bmicroRNA 106b121704334417043425Rat
1310233Ap4m1adaptor related protein complex 4 subunit mu 1121704976617055954Rat
1311608Taf6TATA-box binding protein associated factor 6121705586417064244Rat
1307636Cnpy4canopy FGF signaling regulator 4121706464217070755Rat
1306932Mblac1metallo-beta-lactamase domain containing 1121707146517072736Rat
1588255Nxpe5neurexophilin and PC-esterase domain family, member 5121709762417119700Rat
1587058Nxpe5l2neurexophilin and PC-esterase domain family, member 5 like 2121712410417142519Rat
1587046Ptmal1prothymosin alpha like 1121715294917153791Rat
7675853LOC102551138uncharacterized LOC102551138121717846417200736Rat
1559954Nxpe5l1neurexophilin and PC-esterase domain family, member 5-like 1121718656617196784Rat
41070362LOC120095896NXPE family member 3-like121720844017225545Rat
1562319Nxpe5l3neurexophilin and PC-esterase domain family, member 5 like 3121723831117252723Rat
1309735Lamtor4late endosomal/lysosomal adaptor, MAPK and MTOR activator 4121725865617262478Rat
1305455Trappc14trafficking protein particle complex subunit 14121726274817267093Rat
1561105Gal3st4galactose-3-O-sulfotransferase 4121726796317276951Rat
621363Gpc2glypican 2121727787517284297Rat
621333Stag3STAG3 cohesin complex component121728467717314936Rat
1585866PvrigPVR related immunoglobulin domain containing121736372117365577Rat
1559588Pilrb2l1paired immunoglobin like type 2 receptor beta 2 like 1121739884417404810Rat
1562930Vom2r61vomeronasal 2 receptor, 61121743891117465634Rat
1598200Vom2r62vomeronasal 2 receptor, 62121752466217542226Rat
11466946Vmn2r116l-ps4vomeronasal 2, receptor 116 like, pseudogene 4121758263517615711Rat
1564022Vom2r63vomeronasal 2 receptor, 63121762514117652806Rat
1562525Pilrb2l1paired immunoglobin like type 2 receptor beta 2 like 1121767486017682715Rat
1566006Pilrb2l1paired immunoglobin like type 2 receptor beta 2 like 1121772021317732681Rat
41122052Rap1b-ps1RAP1B, member of RAS oncogene family, pseudogene 1121773295517734674Rat
40977068Pilrb2l1paired immunoglobin like type 2 receptor beta 2 like 1121774431517756074Rat
41102335Rap1b-ps2RAP1B, member of RAS oncogene family, pseudogene 2121775685017757928Rat
1561143Pilrb2paired immunoglobin like type 2 receptor beta 2121777304717779527Rat
6497409Pilrapaired immunoglobin-like type 2 receptor alpha121778716917798149Rat
6497217Zcwpw1l1zinc finger CW-type and PWWP domain containing 1-like 1121779865017812208Rat
7553419Pilrb1l1paired immunoglobin-like type 2 receptor beta 1 like 1121782366217828030Rat
1598199Vom2r-ps104vomeronasal 2 receptor, pseudogene 104121786250917880232Rat
41389804Vmn2r116l-ps7vomeronasal 2, receptor 116 like, pseudogene 7121790355317929309Rat
41145634Vmn2r116l-ps10vomeronasal 2, receptor 116 like, pseudogene 10121794226217956785Rat
1641975Vom2r-ps107vomeronasal 2 receptor, pseudogene 107121801328818014187Rat
41105168Vmn2r116l-ps11vomeronasal 2, receptor 116 like, pseudogene 11121803529818043422Rat
1583509Pilrb1l1paired immunoglobin-like type 2 receptor beta 1 like 1121808141018089619Rat
41031955Pilrb-ps5paired immunoglobin-like type 2 receptor beta, pseudogene 5121818675818190046Rat
1561730Pilrb2l3paired immunoglobin like type 2 receptor beta 2 like 3121821053518216471Rat
41017732Trnag-acc1transfer RNA glycine (anticodon ACC) 1121822243818222512Rat
41111820Pilrb1l1paired immunoglobin-like type 2 receptor beta 1 like 1121822248018237114Rat
1559499Pilrb-ps7paired immunoglobin-like type 2 receptor beta, pseudogene 7121825144218257788Rat
1626043Vom2r-ps103vomeronasal 2 receptor, pseudogene 103121829031018300323Rat
41201467Vmn2r116l-ps8vomeronasal 2, receptor 116 like, pseudogene 8121831329718350370Rat
1626049Vom2r-ps101vomeronasal 2 receptor, pseudogene 101121837651218387463Rat
1584665Vom2r64vomeronasal 2 receptor, 64121841940918449218Rat
1625996Vom2r-ps100vomeronasal 2 receptor, pseudogene 100121846688518480996Rat
1584675Pilrb1paired immunoglobin-like type 2 receptor beta 1121851616118525375Rat
1563400Pilrb2l2paired immunoglobin like type 2 receptor beta 2 like 2121856684118580286Rat
6496729Pilrb-ps1paired immunoglobin-like type 2 receptor beta, pseudogene 1121860115618607655Rat
1560262Pilrb-ps6paired immunoglobin-like type 2 receptor beta, pseudogene 6121860905518630916Rat
1596422Pilrb2l1paired immunoglobin like type 2 receptor beta 2 like 1121863684418651872Rat
41169192LOC120095853uncharacterized LOC120095853121865363018661701Rat
40963637Pilrb-ps4paired immunoglobin-like type 2 receptor beta, pseudogene 4121870450918710373Rat
41202788LOC120095904uncharacterized LOC120095904121872580418728687Rat
11492645Pilrb-ps2paired immunoglobin-like type 2 receptor beta, pseudogene 2121877185018777708Rat
1597726Pilrbl1paired immunoglobin-like type 2 receptor beta like 1121879284018799391Rat
40942766Pilrb-ps3paired immunoglobin-like type 2 receptor beta, pseudogene 3121880167318811757Rat
7556717Pilrb1l2paired immunoglobin-like type 2 receptor beta 1 like 2121881408518837515Rat
9261510LOC103693637ras-related protein Rap-1b pseudogene121882114618821924Rat
41314880Rap1b-ps3RAP1B, member of RAS oncogene family, pseudogene 3121883809818839898Rat
41173580Pilrb2l1paired immunoglobin like type 2 receptor beta 2 like 1121885345218861001Rat
6498401LOC100910497paired immunoglobulin-like type 2 receptor alpha-like121886630118881290Rat
1305405Zcwpw1zinc finger CW-type and PWWP domain containing 1121888062518910713Rat
1560550Mepcemethylphosphate capping enzyme121891179618916515Rat
1584367Ppp1r35protein phosphatase 1, regulatory subunit 35121891590918919253Rat
11442159Spacdrsperm acrosome developmental regulator121893060818936787Rat
1584380Tsc22d4TSC22 domain family, member 4121893915018952008Rat
1310964Nyap1neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1121895619218967624Rat
1591278Echdc2-ps1enoyl CoA hydratase domain containing 2, pseudogene 1121898935318992172Rat
1306590Agfg2ArfGAP with FG repeats 2121901222819048433Rat
69317Irs3insulin receptor substrate 3121905314819055286Rat
1562406Sap25Sin3A-associated protein 25121905576219057425Rat
1306145Lrch4leucine rich repeats and calponin homology domain containing 4121905758219072573Rat
1305095Fbxo24F-box protein 24121907266819083067Rat
11511026LOC108352432uncharacterized LOC108352432121907583919095304Rat
3270Pcolceprocollagen C-endopeptidase enhancer121908419119090508Rat
1304973Mospd3motile sperm domain containing 3121909520319100303Rat
1310152Tfr2transferrin receptor 2121910767319124622Rat
1307763Actl6bactin-like 6B121912488719141419Rat
69319Gnb2G protein subunit beta 2121915900219164021Rat
1309933Gigyf1GRB10 interacting GYF protein 1121916607019181570Rat
1306413Pop7POP7 homolog, ribonuclease P/MRP subunit121918938419190425Rat
2559Epoerythropoietin121920425819207948Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
5683878D12Hmgc3194121300829613008490Ratregion
5683880D12Hmgc4170121310437613104548Ratregion
502796544.MMHAP70FRG11.seq189121313121613131405Ratregion
5061402BF396334237121327745513277692Ratregion
5076662RH139306121121335155113351672Ratregion
44952D12Got27156121343671213436870Ratregion
5086695BE115283162121356318313563345Ratregion
44950D12Wox5116121363552313635658Ratregion
5077440RH139757198121375786613758064Ratregion
5059550BE097282181121387536513875546Ratregion
5079716RH141162186121388277713882963Ratregion
5056145RH144209101121388348313883584Ratregion
5040488RH128312186121388585113886037Ratregion
5074978RH138328140121388657013886710Ratregion
5054941RH143514267121388870213888969Ratregion
5075490RH138624150121388883413888984Ratregion
44954D12Got29279121392476113925040Ratregion
5078464RH140358187121393744713937634Ratregion
5046776RH131948184121398239313982577Ratregion
5032271AI414930135121402509714025232Ratregion
5084938AI236775145121403057014031271Ratregion
5057806BI277157205121408246714082860Ratregion
5051405AI595374154121411065214110806Ratregion
5499901UniSTS:235351167121411079914110966Ratregion
5029191RH143860165121411084014111005Ratregion
5040348RH128231197121419649614196693Ratregion
5045782RH131376209121429998614300195Ratregion
44956D12Got30158121446396714464125Ratregion
5044918RH130878153121463052714630680Ratregion
5500551RH135954170121472489314725063Ratregion
5031570AU047888216121479276414792980Ratregion
5067214AU047892255121479276414793019Ratregion
5040418RH128272208121481196614812174Ratregion
5502686Tmem184a0121482930314829966Ratregion
5072682RH136991220121483285614833076Ratregion
5501387Mafk588121483465614835244Ratregion
5058676BI284461184121483505314835238Ratregion
5504789UniSTS:2741821383121483659514837978Ratregion
5503986UniSTS:2571050121483699514837963Ratregion
5505466UniSTS:530587421121487436114874782Ratregion
5079044RH140702206121488579114885997Ratregion
5081016RH141916184121488585914886043Ratregion
5067182AU047911207121494228014942487Ratregion
33725D12Mit1259121502494215025183Ratregion
38094D12Rat47209121507055115070761Ratregion
5074172RH137863142121508424415084386Ratregion
5088139Uncx4.198121509279115092889Ratregion
7206646Uncx762121509328415094046Ratregion
5045500RH131214150121517246215172612Ratregion
5050558RH134125189121521725315217442Ratregion
5063520BE107745162121522979215229954Ratregion
5046828RH131978185121525209915252284Ratregion
5081388AI454263194121531086415311058Ratregion
5090261AU049646126121531128715311413Ratregion
5049310RH133407186121531262315312809Ratregion
62471D2Uia1271121531710015317367Ratregion
5046324RH131687211121537579615376007Ratregion
5039900RH127972197121537703715377234Ratregion
5025366RH128037199121537784015378039Ratregion
5052767RH142261173121539647415396647Ratregion
5044570RH130679182121539647415396656Ratregion
5499895UniSTS:235349192121539658615396778Ratregion
5065274BE121325159121541681815416977Ratregion
5038900RH127397183121545384115454024Ratregion
5502918Prkar1b751121562410215624853Ratregion
5047598RH132420208121562464215624850Ratregion
5050348RH134004190121564244215642632Ratregion
5060396AW525445170121564519015645360Ratregion
37272D12Rat28120121580606515806191Ratregion
5505116LOC783396150121581353015813680Ratregion
5045060RH130960182121582687915827061Ratregion
40408D12Rat91160121587265315872803Ratregion
5065714BF406262207121589157615891783Ratregion
5075028RH138357220121597935815979578Ratregion
5050418RH134045201121603969416039895Ratregion
5064902BE108699150121624945616249606Ratregion
5043508RH130065196121630434816304544Ratregion
5046526RH131804181121631043316310614Ratregion
5041142RH128686150121631792416318074Ratregion
44962D12Got36139121637919316379328Ratregion
5060020BF400282137121642471516424853Ratregion
5086535AW529990171121643362116433792Ratregion
5068848AU046888175121668258616682756Ratregion
5047648RH132448181121676227916762460Ratregion
5045860RH131420212121676377616763988Ratregion
5026390RH132022208121680627916806487Ratregion
5056215RH144250222121689725716897479Ratregion
44959D12Got34207121690215316902360Ratregion
5080834RH141809180121690761816907812Ratregion
5062218BF397585213121691167316911886Ratregion
629605D12Hmgc1181121693293516933106Ratregion
5070191RH94525173121693691216937085Ratregion
5075242RH138481168121693730316937471Ratregion
5027309C87323158121698237116982529Ratregion
5082587BF416395169121698410416984273Ratregion
5076140RH139002205121698743016987635Ratregion
5502307RH124339154121698989516990049Ratregion
5502307RH124339154121698989516990049Ratregion
5049386RH133451216121701325417013470Ratregion
5065320BE121431161121701953117019692Ratregion
5031169BE116815180121702291417023094Ratregion
5077384RH139725204121704189017042094Ratregion
5040018RH128042210121704236017042716Ratregion
5500240AI747533103121704270517043542Ratregion
5073004RH137179181121705597317056154Ratregion
5065718BF406289115121705720617057321Ratregion
5063286BI301666185121706271417062900Ratregion
44960D12Got35142121709872117098867Ratregion
44963D12Got32176121709874417098921Ratregion
5041864RH129103181121726217117262352Ratregion
5061796AW533576155121726801617268171Ratregion
37318D12Rat29150121731067817310845Ratregion
5044526RH130654157121736540517365562Ratregion
5088579AU048654176121742593117426107Ratregion
5499615MARC_2660-2661:991933047:1307121773349017733786Ratregion
5504314D12S1240E100121773411417734214Ratregion
5499615MARC_2660-2661:991933047:1307121775689317757189Ratregion
5504314D12S1240E100121775751717757617Ratregion
502792734.MMHAP64FRD10.seq167121783206317832230Ratregion
5029597BF39272691121823055218230643Ratregion
502792734.MMHAP64FRD10.seq167121826180818261975Ratregion
5683882D12Hmgc5193121837715918377352Ratregion
5047034RH132096181121862447318624655Ratregion
5029597BF39272691121866157218661663Ratregion
5499615MARC_2660-2661:991933047:1307121882122918821524Ratregion
5499615MARC_2660-2661:991933047:1307121883832518838621Ratregion
5504314D12S1240E100121883894918839049Ratregion
1639781D12Got226103121885849018858588Ratregion
5029583BE101310183121891477118914954Ratregion
5038642C7881584121891612518916209Ratregion
5036229RH125705271121891612718916398Ratregion
5052771RH142264200121891628218916482Ratregion
5035172AW535112158121891724618917404Ratregion
5045482RH131203181121891808518918266Ratregion
5072352RH136799122121893095418931076Ratregion
5052917RH142348187121893931618939503Ratregion
5049214RH133351202121893935518939557Ratregion
5054111RH143037258121894651918946777Ratregion
5058468BI290373119121904175919041878Ratregion
5077820RH139978188121904339719043585Ratregion
5073650RH137560171121904820619048377Ratregion
5504742PMC86565P2601121905335319053954Ratregion
5026248RH131481203121905506519055268Ratregion
5052035RH94802159121905508519055244Ratregion
5080384RH141548208121905818219058390Ratregion
5502066MARC_26575-26576:1033748265:10121909595319096548Ratregion
5039264RH127606214121909906119099369Ratregion
5502126MARC_5081-5082:996690120:1683121912715019127833Ratregion
5505961Gnb2390121916298219163459Ratregion
5032677RH134888187121918832419188511Ratregion
5030377AI029876207121919015919190366Ratregion
5683884D12Hmgc6121921261419212979Ratregion
5683884D12Hmgc6121921274219212979Ratregion
Position Markers

Flank 1: (D12Hmgc3)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21213,008,296 - 13,008,490 (+)MAPPER
Rnor_6.01215,085,585 - 15,085,778NCBI
Rnor_5.01217,102,817 - 17,103,010UniSTS
Celera1214,777,134 - 14,777,327UniSTS
Cytogenetic Map12q11UniSTS
Flank 2: (D12Hmgc6)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21219,212,614 - 19,212,979 (+)MAPPER
mRatBN7.21219,212,742 - 19,212,979 (+)MAPPER
Rnor_6.01222,283,271 - 22,283,507NCBI
Rnor_6.01222,283,062 - 22,283,507NCBI
Rnor_5.01224,299,924 - 24,300,160UniSTS
Rnor_5.01224,299,715 - 24,300,160UniSTS
Celera1221,017,537 - 21,017,777UniSTS
Cytogenetic Map12 RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1600391Edcs2Endometrial carcinoma susceptibility QTL23.50.01uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)12683319017870186Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12844949028302290Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)12931821632103380Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121107382524234895Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382528064557Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121300829619212979Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121363552330827399Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121363552335682913Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)121502518320794014Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121555082638478808Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)121587265332974238Rat
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general 6.1 Mb (4-19.5 Mb) segment of SS significantly elevated the blood pressure, albuminuria and proteinuria 7204442
qtl_general 12,673 SNPs and 133 genes were found in this region 7204442
qtl_general measurement method: 9 weeks old rats were fed 1% NaCl diet and mean arterial pressure was recorded for 3 days by a telemetry transmitter implantation with a catheter inserted into the abdominal aorta; then given 8% NaCl diet for 7 days and MAP recorded 7204442
qtl_general animals used: 9 weeks old male rats 7204442
qtl_general software used: ANOVA 7204442
qtl_general generation of congenic SS.BN-(D12Hmgc3-AU047911)/Mcwi which has the same phenotypes as SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi, decreased the locus to 830kb (chr12:14.36-15.19 Mb), this region has 14 genes 8693701