Xhs2 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Xhs2 (X-ray hypersensitivity QTL 2) Rattus norvegicus

Symbol: Xhs2
Name: X-ray hypersensitivity QTL 2
RGD ID: 70179
Trait: intestine integrity trait   (VT:0010554)    
Measurement Type: post-insult time to onset of moribundity   (CMO:0001896)    
LOD Score: 3.2
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,321,100 - 19,121,980RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0116,033,078 - 20,130,904RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0117,574,243 - 21,618,253RGDRnor5.0
RGSC_v3.4115,833,442 - 19,577,925RGDRGSC3.4
RGSC_v3.1115,833,505 - 19,577,987RGD
Cross Type: Not Available
Strains Crossed: LEC BN/Sea 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
BN/Sea  (IEA)
LEC  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Genetic linkage analysis of X-ray hypersensitivity in the LEC mutant rat. Agui T, etal., Mamm Genome 2000 Oct;11(10):862-5.
2. QTL Data Transfer QTL data import from the RatMap database

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
619706Ptprkprotein tyrosine phosphatase, receptor type, K11673889617236687Rat
621016Pde7bphosphodiesterase 7B11517400115493267Rat
1305053Arhgap18Rho GTPase activating protein 1811840353118637306Rat
1308509Hbs1lHBS1-like translational GTPase11609252916170082Rat
1305474L3mbtl3L3MBTL histone methyl-lysine binding protein 311898876319089247Rat
1308889Lama2laminin subunit alpha 211767267518320641Rat
1303040Ahi1Abelson helper integration site 111576804715886744Rat
1560020MybMYB proto-oncogene, transcription factor11593977115973367Rat
1560849Themisthymocyte selection associated11643390616623889Rat
1590218Aldh8a1aldehyde dehydrogenase 8 family, member A111618394016203385Rat
1589061Rplp0-ps4ribosomal protein lateral stalk subunit P0, pseudogene 411735763717358522Rat
1587834Samd3sterile alpha motif domain containing 311910303619147832Rat
1586110Ruvbl1-ps2RuvB-like AAA ATPase 1, pseudogene 211751953517521754Rat
1598314LOC361456similar to ribosomal protein S1011894812418948790Rat
2321467LOC100360791tumor protein, translationally-controlled 111910738919108208Rat
7744936Amn1-ps1antagonist of mitotic exit network 1, pseudogene 111653730916537787Rat
9075724LOC103690928U6 snRNA-associated Sm-like protein LSm5 pseudogene11846343218469878Rat
11363865LOC10834900860S ribosomal protein L7a pseudogene11653594916536761Rat
11439716LOC108349499uncharacterized LOC10834949911557391515579154Rat
41357357LOC120098805uncharacterized LOC12009880511688652316887639Rat
41325772LOC120100129U6 spliceosomal RNA11776047217760578Rat
41331278LOC120100369small nucleolar RNA SNORA4111567916915679309Rat
41150335LOC120098803uncharacterized LOC12009880311566331615668122Rat
41177791LOC120098806uncharacterized LOC12009880611679110416795556Rat
41071539LOC120100143U6 spliceosomal RNA11832812518328231Rat
41104967LOC120097699cytochrome b-c1 complex subunit 10-like11875161218751912Rat
41228825Atg4b-ps1autophagy related 4B, cysteine peptidase, pseudogene 111655334516558705Rat
41198301LOC120098802uncharacterized LOC12009880211556374615573829Rat
41312082LOC120100169U6 spliceosomal RNA11624352816243631Rat
41024257Rpl23a-ps3ribosomal protein L23a, pseudogene 311615578316163479Rat
41314157LOC120098807uncharacterized LOC12009880711824565718317592Rat
41078939LOC120098804uncharacterized LOC12009880411672294416736191Rat
41248032Npm1-ps5nucleophosmin 1, pseudogene 511800684618007514Rat
41257596LOC120097350translation initiation factor IF-2-like11898864418992023Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
37296D1Rat14821111576058215760793Ratregion
35467D1Rat717311543162115431794Ratregion
37198D1Rat18622511532110015321325Ratregion
42448D1Rat39220011912178019121980Ratregion
43191D1Got2318011821206118212241Ratregion
43192D1Got2416511863955918639724Ratregion
43193D1Got1115011653480616534956Ratregion
43194D1Got2517311878235418782525Ratregion
43195D1Got1918611727253717272723Ratregion
43196D1Got2220411851322218513426Ratregion
625791D1Got2021911534181115342030Ratregion
1635563D1Got3019111860661118606702Ratregion
5029335RH14440519211852949618529688Ratregion
5030471BF39788015111534037815340529Ratregion
5025418RH12824020711616967716169884Ratregion
5056413RH14436420711679337816793585Ratregion
5059732BI29183921611850732718507543Ratregion
5054317RH14315514411589089215891036Ratregion
5043784RH13022518011613351116133691Ratregion
5041714RH12901618011832043618320616Ratregion
5046724RH13191820411589183315892037Ratregion
5042482RH12946020811673758916737797Ratregion
5040950RH12857718111673762116737802Ratregion
5077496RH13978918711643165616431843Ratregion
5071964RH13538618411532949915329683Ratregion
5074468RH13803421111791035917910570Ratregion
5073492RH13746718411588269915882883Ratregion
5069776AU02881210411716668417166783Ratregion
5060288AW53112917611584260415842780Ratregion
5065246BE12127920411587901315879217Ratregion
5063074BF41028219111899173118991922Ratregion
5066298PMC140821P116911610473916104908Ratregion
5087398EST-CFZ9775635211771811217718464Ratregion
5083145BF39087216011610502816105188Ratregion
5085094BQ20957716811600277216002940Ratregion
5090033AU04951028911787099917871286Ratregion
5089023AU04890919511567294415673139Ratregion
5507133UniSTS:22476416011595900715959167Ratregion
5499607MARC_2026-2027:991932441:135311910750919107862Ratregion
5501123PMC140821P213211616881016168942Ratregion
Position Markers

Flank 1: (D1Rat186)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2115,321,100 - 15,321,325 (+)MAPPER
Rnor_6.0116,033,078 - 16,033,302NCBI
Rnor_5.0117,574,243 - 17,574,467UniSTS
RGSC_v3.4115,833,442 - 15,833,667RGD
RGSC_v3.4115,833,443 - 15,833,667UniSTS
RGSC_v3.1115,833,505 - 15,833,729RGD
Celera113,748,791 - 13,749,015UniSTS
RH 3.4 Map1166.11RGD
RH 3.4 Map1166.11UniSTS
RH 2.0 Map183.1RGD
SHRSP x BN Map111.45RGD
Cytogenetic Map1p12UniSTS
Peak: (D1Rat391)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2119,646,188 - 19,646,425 (+)MAPPER
Rnor_6.0120,665,311 - 20,665,547NCBI
Rnor_5.0122,147,803 - 22,148,039UniSTS
RGSC_v3.4120,110,663 - 20,110,899UniSTS
RGSC_v3.4120,110,662 - 20,110,899RGD
RGSC_v3.1120,110,725 - 20,110,961RGD
Celera118,527,033 - 18,527,257UniSTS
RH 3.4 Map1180.4RGD
RH 3.4 Map1180.4UniSTS
RH 2.0 Map1118.7RGD
SHRSP x BN Map113.75RGD
Flank 2: (D1Rat392)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2119,121,780 - 19,121,980 (+)MAPPER
Rnor_6.0120,130,705 - 20,130,904NCBI
Rnor_5.0121,618,054 - 21,618,253UniSTS
RGSC_v3.4119,577,725 - 19,577,925RGD
RGSC_v3.4119,577,726 - 19,577,925UniSTS
RGSC_v3.1119,577,787 - 19,577,987RGD
Celera117,513,733 - 17,513,932UniSTS
SHRSP x BN Map112.98RGD
SHRSP x BN Map112.98UniSTS
Cytogenetic Map1p12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1124744506Rat
2298546Neuinf4Neuroinflammation QTL 45.1nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1128736750Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1132356093Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1132356093Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1132356093Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)150910843284926Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1224439043433040Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1592587724697545Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)11148148232355910Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)11532110019121980Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11543162149361612Rat
5684999Bss102Bone structure and strength QTL 1025.50.00000072tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11543162149361612Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11620621049268520Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Xhs2

RGD Curation Notes
Note Type Note Reference