Bp65 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp65 (Blood pressure QTL 65) Rattus norvegicus

Symbol: Bp65
Name: Blood pressure QTL 65
RGD ID: 70166
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: 5.8
P Value: Not Available
Variance: 7.5
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X1,447,972 - 11,374,346RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0X1,662,453 - 12,370,298RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0X2,456,432 - 13,162,713RGDRnor5.0
RGSC_v3.4X994,805 - 45,994,805RGDRGSC3.4
RGSC_v3.1X1,048,124 - 46,048,124RGD
Cross Type: F2
Strains Crossed: SBH/Ygl SBN/Ygl 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
hypertension  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
SBH/Ygl  (IEA)
SBN/Ygl  (IEA)

References

References - curated
# Reference Title Reference Citation
1. QTL Data Transfer QTL data import from the RatMap database
2. Role of chromosome X in the Sabra rat model of salt-sensitive hypertension. Yagil C, etal., Hypertension 1999 Jan;33(1 Pt 2):261-5.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1303052Usp11ubiquitin specific peptidase 11X14733491489520Rat
620584Cdk16cyclin-dependent kinase 16X14928141504309Rat
1359327Uba1ubiquitin-like modifier activating enzyme 1X15087001530677Rat
631366Rbm10RNA binding motif protein 10X15403991572571Rat
1563698Ndufb11NADH:ubiquinone oxidoreductase subunit B11X15728051575063Rat
41084699LOC120099502U2 spliceosomal RNAX15765731576750Rat
41340321Foxn3-ps1forkhead box N3, pseudogene 1X15905401593962Rat
1584906Rps2-ps19ribosomal protein S2, pseudogene 19X16002771604262Rat
3560RgnregucalcinX16190301634456Rat
41177495LOC120099297uncharacterized LOC120099297X16316771719845Rat
1564855Ruvbl1-ps1RuvB-like AAA ATPase 1, pseudogene 1X16401381641886Rat
1563945Jade3jade family PHD finger 3X16688731848781Rat
1565124Rp2RP2 activator of ARL3 GTPaseX18725811916704Rat
1565634Rpl7-ps28ribosomal protein L7, pseudogene 28X19754051976133Rat
1582764Slc25a39-ps2solute carrier family 25 member 39, pseudogene 2X19821191983242Rat
2325118Egln1-ps1egl-9 family hypoxia-inducible factor 1, pseudogene 1X21921432195194Rat
1561385Slc9a7solute carrier family 9 member A7X22140642395052Rat
41388570Actb-ps7actin, beta, pseudogene 7X22811102282237Rat
1303028Chst7carbohydrate sulfotransferase 7X23962602432828Rat
1582752Actb-ps8actin, beta, pseudogene 8X24804892481616Rat
7576093Rcc1-ps1regulator of chromosome condensation 1, pseudogene 1X24860512499797Rat
40998145LOC120099483small nucleolar RNA SNORA48X26886362688779Rat
1582737Ssu72-ps2Ssu72 RNA polymerase II CTD phosphatase, pseudogene 2X31306443131229Rat
2323472Morf4l1-ps2mortality factor 4 like 1, pseudogene 2X31548763157791Rat
41224812LOC120099430U6 spliceosomal RNAX31813523181455Rat
1561575Pgam1-ps12phosphoglycerate mutase 1, pseudogene 12X33319183332681Rat
41021103LOC120099382uncharacterized LOC120099382X33488133430507Rat
40930304LOC120099383uncharacterized LOC120099383X33606983373943Rat
41195614LOC120099384uncharacterized LOC120099384X34147533450707Rat
2325544Mir222microRNA 222X34289043429006Rat
2325451Mir221microRNA 221X34294653429573Rat
41323899Fam156a-ps2family with sequence similarity 156, member A, pseudogene 2X35239163525690Rat
6504298Nsa2-ps19NSA2 ribosome biogenesis factor, pseudogene 19X37317033755404Rat
2323267LOC100359876multifunctional protein ADE2-likeX40328274034310Rat
1559731Dipk2bdivergent protein kinase domain 2BX42054864274939Rat
11511896LOC108349162uncharacterized LOC108349162X42788024280122Rat
9275041Kdm6alysine demethylase 6AX43374664477100Rat
41137236LOC120099295uncharacterized LOC120099295X44876304527042Rat
1560427Dusp21dual specificity phosphatase 21X44880214488877Rat
41246330LOC120099547U4 spliceosomal RNAX45414924541636Rat
41355427LOC120099406U6 spliceosomal RNAX47302574730359Rat
1564748RGD1564748similar to Mortality factor 4-like protein 2 (MORF-related gene X protein)X47537444762480Rat
41357493Hmgb1-ps7high-mobility group box 1, pseudogene 7X47908354791553Rat
1597252Arl2-ps3ADP-ribosylation factor-like 2, pseudogene 3X48283304828818Rat
1563372Fundc1FUN14 domain containing 1X50836355100293Rat
11412301LOC108349111ferritin light chain 1 pseudogeneX52604755263586Rat
41000091LOC120099197uncharacterized LOC120099197X53230925360904Rat
1597239Psma2-ps2proteasome 20S subunit alpha 2, pseudogene 2X53309325331653Rat
1563388Efhc2EF-hand domain containing 2X53604995564004Rat
40979039LOC120099196putative deoxyribonuclease TATDN2X54178715420297Rat
1563968Ndpnorrin cystine knot growth factor NDPX57964875820934Rat
1597220Blzf1-ps1basic leucine zipper nuclear factor 1, pseudogene 1X58258645834539Rat
3041Maobmonoamine oxidase BX59073276010996Rat
61898Maoamonoamine oxidase AX60321726098308Rat
7559672Aebp2-ps1AE binding protein 2, pseudogene 1X61822646190189Rat
1597208Qprt-ps2quinolinate phosphoribosyltransferase, pseudogene 2X62970436298025Rat
1562289RGD1562289similar to RIKEN cDNA C330016H24X63812186383349Rat
2322703Rae1-ps1ribonucleic acid export 1, pseudogene 1X70602007082473Rat
1596007Ppia-ps14peptidylprolyl isomerase A, pseudogene 14X74825367483024Rat
9130933LOC103690789uncharacterized LOC103690789X76030667697170Rat
1562126Ppp1r2-ps1protein phosphatase 1, regulatory (inhibitor) subunit 2, pseudogene 1X77120937712969Rat
41265165LOC120099316uncharacterized LOC120099316X77513237784196Rat
7521242LOC102552945ribosomal L1 domain-containing protein 1-likeX77866697787598Rat
1565965RGD1565965hypothetical gene supported by NM_021262; AF171072X78715747872173Rat
9170641LOC103690799cytochrome b-c1 complex subunit 7 pseudogeneX80320658034430Rat
41213711Snw1-ps6SNW domain containing 1, pseudogene 6X85983988599036Rat
11465968Trnaq-uug5transfer RNA glutamine (anticodon UUG) 5X88880578888128Rat
62004Caskcalcium/calmodulin dependent serine protein kinaseX88995009243014Rat
2318147Gpr82G protein-coupled receptor 82X90796539081259Rat
1563681Gpr34G protein-coupled receptor 34X91048299113796Rat
40967234LOC120099226uncharacterized LOC120099226X91249679148825Rat
11500710Trnad-guc13transfer RNA aspartic acid (anticodon GUC) 13X91811919181262Rat
1561300NyxnyctalopinX92808649301900Rat
41213739LOC120099244uncharacterized LOC120099244X94238049431464Rat
41395655Gapdh-ps81Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 81X94463829448695Rat
1564771Ddx3xDEAD-box helicase 3, X-linkedX94795329493455Rat
7642326LOC102547042uncharacterized LOC102547042X95287309537665Rat
1560056Usp9xubiquitin specific peptidase 9, X-linkedX95888259726993Rat
40974845Rps19-ps3ribosomal protein S19, pseudogene 3X96771759677812Rat
40929117Trnat-agu31transfer RNA threonine (anticodon AGU) 31X97067739706845Rat
6492000Ppia-ps1peptidylprolyl isomerase A, pseudogene 1X98327539833488Rat
1563226Ube2q2lubiquitin-conjugating enzyme E2Q family member 2-likeX98391829840703Rat
1595957Tma7-ps1translation machinery associated 7 homolog, pseudogene 1X98638259864377Rat
1564613RGD1564613similar to MGC40405 proteinX1000390310005865Rat
1560170Med14mediator complex subunit 14X1003674910127910Rat
1565685RGD1565685similar to RIKEN cDNA 1810030O07X1012807010150904Rat
1563528Mpc1lmitochondrial pyruvate carrier 1-likeX1014627410147145Rat
1561269Atp6ap2ATPase H+ transporting accessory protein 2X1018398310210948Rat
41396065LOC120099278uncharacterized LOC120099278X1021960210233127Rat
7531977LOC102549122uncharacterized LOC102549122X1033398010345524Rat
2321917Trmt112-ps3tRNA methyltransferase activator subunit 11-2, pseudogene 3X1044287710443229Rat
1562735BcorBCL6 co-repressorX1060975610729613Rat
11360277LOC108353263WAS/WASL-interacting protein family member 2-likeX1067895810687491Rat
1559951RGD1559951similar to 60S ribosomal protein L37aX1078844510788843Rat
41102188LOC120099560U6 spliceosomal RNAX1079675010796856Rat
41023824LOC120099399U6 spliceosomal RNAX1092822310928326Rat
40971929LOC120099268uncharacterized LOC120099268X1096291410972337Rat
41191886LOC120099262uncharacterized LOC120099262X1104065911043082Rat
11367266LOC108349205uncharacterized LOC108349205X1127857711279975Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
11236DXWox11136X16237151623851Ratregion
33567DXMit1140X1115443711154575Ratregion
36079DXRat3129X1051890610519043Ratregion
37348DXRat44223X1131080611311041Ratregion
37482DXRat120143X29821862982331Ratregion
37536DXRat49249X1054429210544536Ratregion
36474DXRat4190X1137418311374346Ratregion
35030DXRat2160X14479721448129Ratregion
39736DXRat80184X95497979549959Ratregion
38490DXRat48149X91742249174361Ratregion
40354DXRat74145X49871984987335Ratregion
39156DXRat39239X1124853411248769Ratregion
39482DXRat76207X1042802410428229Ratregion
41398DXRat77155X1108628911086440Ratregion
40804DXRat78203X87744028774589Ratregion
45710DXGot1232X99991379999371Ratregion
45711DXGot3274X1021626110216535Ratregion
45712DXGot5124X1061841310618539Ratregion
60683DXGot4213X90249629025175Ratregion
1631499DXGot144295X21672022167497Ratregion
1631643DXGot129143X1047679910476939Ratregion
1639943DXGot107137X14565261456663Ratregion
1640586DXGot196202X60912606091463Ratregion
1637943DXGot149247X57887695789018Ratregion
7205870PMC85795P4500X22815892282085Ratregion
7205870PMC85795P4500X24806402481136Ratregion
7192490Cask98X91459899146087Ratregion
5035879PMC275467P1254X22815922281843Ratregion
5035879PMC275467P1254X24808822481133Ratregion
5039178RH1275570X95890029589202Ratregion
5039028RH127471203X1012756510127768Ratregion
5037205RH91894131X1068525410685385Ratregion
5035581DBX87X94798489479935Ratregion
5035667RH78345124X94805809480704Ratregion
5035689DXS7582114X1012335110123465Ratregion
5031370PMC152551P1267X22815922281856Ratregion
5031370PMC152551P1267X24808692481133Ratregion
5034123RH141451210X15381871538397Ratregion
5026386RH132006197X50999975100194Ratregion
5029037RH143274158X16409041641062Ratregion
5029243RH144057152X58206195820771Ratregion
5027075SAG111X1058858210588693Ratregion
5032519SHGC-33274125X94805799480704Ratregion
5032587RH134557192X1015046210150653Ratregion
5034978Ddx3273X94816449481917Ratregion
5027997L25126106X94819139482019Ratregion
5055905RH144070148X90836609083808Ratregion
5056091RH144177195X48276244827823Ratregion
5056375RH144342171X14921941492365Ratregion
5059688BE097638194X92805469280740Ratregion
5052337U42386151X94803899480540Ratregion
5058300BF386985181X23883332388514Ratregion
5059174BE102970179X1018578710185966Ratregion
5050640RH134173214X97076079707821Ratregion
5052579RH125670232X95928149593046Ratregion
5054179RH143076299X1014765010147949Ratregion
5052765RH142260154X95918019591955Ratregion
5052817RH142290158X16206291621248Ratregion
5052881RH142328187X19821301982317Ratregion
5053039RH142419201X60106846010885Ratregion
5041782RH129056182X60107706010952Ratregion
5044286RH130515181X34301723430353Ratregion
5043770RH130217219X23947612394980Ratregion
5039630RH127816190X60309036031093Ratregion
5039694RH127853186X94796469479832Ratregion
5042822RH129666190X15087221508912Ratregion
5074926RH138299123X23328552332978Ratregion
5080652RH141703203X95915489591751Ratregion
5077490RH139786219X60155156015734Ratregion
5078318RH140271195X14733581473553Ratregion
5071054RH134860195X14932761493471Ratregion
5071088RH134879218X52034315203873Ratregion
5073600RH137530208X1000485410005062Ratregion
5066672AU048219113X62070676207180Ratregion
5066736AU048181136X1097369010973826Ratregion
5067084AU047974262X1063577110636028Ratregion
5068102AU047346106X55138855513991Ratregion
5068828AU046901232X57887695789003Ratregion
5070486AA989744100X15088321508932Ratregion
5062300BE106498150X1000531810005468Ratregion
5063708BF404609247X89264008926647Ratregion
5062578BF403440192X97117409711932Ratregion
5061406BF396338148X96409279641075Ratregion
5086115BM383929168X1014400210144170Ratregion
5088137Ube1x72X15128211512893Ratregion
5083555BI276143218X1018342910183647Ratregion
5090647AU049878229X27580042758235Ratregion
5090251AU049640234X52488855249123Ratregion
5090267AU049649211X90249609025171Ratregion
5084540AI235339104X95368229537131Ratregion
5503372px-25g4101X75134157513516Ratregion
5503318UniSTS:238005261X98401849840445Ratregion
5503960Cask977X92379029238879Ratregion
5503915UniSTS:256410325X15089281509874Ratregion
5503962UniSTS:25696580X91375549137634Ratregion
5504095px-12d6113X95891849589297Ratregion
5505063Actb0X22812882281798Ratregion
5505063Actb0X24809272481437Ratregion
5507275fa94e111010X28991632900173Ratregion
5499621MARC_3162-3163:991936817:10X19825821982849Ratregion
5500290D20S998119X95927899592908Ratregion
5502555RH125324179X95905279590706Ratregion
5500869G3497694X43778314377925Ratregion
5506421UniSTS:4792191180X15407111541891Ratregion
5502861Ddx3x912X94810409481952Ratregion
Position Markers

Flank 1: (DXRat2)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X1,447,972 - 1,448,129 (+)MAPPER
Rnor_6.0X1,662,453 - 1,662,609NCBI
Rnor_5.0X2,456,432 - 2,456,588UniSTS
SHRSP x BN MapX0.0RGD
SHRSP x BN MapX0.0UniSTS
Peak: (DXRat4)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X11,374,183 - 11,374,346 (+)MAPPER
Rnor_6.0X12,370,136 - 12,370,298NCBI
Rnor_5.0X13,162,551 - 13,162,713UniSTS
RGSC_v3.4X23,494,724 - 23,494,887RGD
RGSC_v3.4X23,494,725 - 23,494,887UniSTS
RGSC_v3.1X23,548,043 - 23,548,205RGD
CeleraX11,993,032 - 11,993,194UniSTS
RH 3.4 MapX74.4UniSTS
RH 3.4 MapX74.4RGD
RH 2.0 Map2150.4RGD
SHRSP x BN MapX0.08RGD
FHH x ACI MapX0.0RGD
Cytogenetic MapX RGD
Flank 2: (DXRat4)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X11,374,183 - 11,374,346 (+)MAPPER
Rnor_6.0X12,370,136 - 12,370,298NCBI
Rnor_5.0X13,162,551 - 13,162,713UniSTS
RGSC_v3.4X23,494,724 - 23,494,887RGD
RGSC_v3.4X23,494,725 - 23,494,887UniSTS
RGSC_v3.1X23,548,043 - 23,548,205RGD
CeleraX11,993,032 - 11,993,194UniSTS
RH 3.4 MapX74.4UniSTS
RH 3.4 MapX74.4RGD
RH 2.0 Map2150.4RGD
SHRSP x BN MapX0.08RGD
FHH x ACI MapX0.0RGD
Cytogenetic MapX RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
70166Bp65Blood pressure QTL 655.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144797211374346Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X144797220991088Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
631204Gluco15Glucose level QTL 150.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X162371522646544Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Bp65

RGD Curation Notes
Note Type Note Reference
qtl_general QTL identifies a region containing a gene or genes that contribute to salt susceptibility in females but not in males 69713
qtl_general number of animals used: 707 F2 animals 69713
qtl_general software used: MAPMAKER/QTL 69713
qtl_general measurement method: basal blood pressure was measured at 6 weeks then 1%NaCl was given in drinking water; after 4 weeks systolic blood pressure was measured 69713