Scl33 QTL Report (Rattus norvegicus)

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QTL Registration

General

QTL: Scl33 (Serum cholesterol QTL 33) Rattus norvegicus

Symbol:

Scl33

Name:

Serum cholesterol QTL 33

RGD ID:

6903300

Trait:

blood cholesterol amount (VT:0000180)

Measurement Type:

plasma total cholesterol level (CMO:0000585)

LOD Score:

2.0

P Value:

0.0125

Variance:

Not Available

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_5.0	8	92,612,869 - 132,457,389	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	8	89,742,772 - 129,041,809	RGD	RGSC3.4

Cross Type:

Not Available

Strains Crossed:

LEW HTG

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Hypercholesterolemia (IAGP)

Metabolic Syndrome (IAGP)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

increased circulating cholesterol level (IDA)

Experimental Data Annotations Click to see Annotation Detail View

Clinical Measurement

plasma total cholesterol level (IDA)

Experimental Condition

control condition (IDA)

Measurement Method

plasma total cholesterol measurement test (IDA)

Vertebrate Trait

blood cholesterol amount (IDA)

Rat Strain

HTG (IEA)

LEW (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat model of familial combined hyperlipidemia as a result of comparative mapping.	Ueno T, etal., Physiol Genomics 2004 Mar 12;17(1):38-47. Epub 2004 Jan 6.

Region

Markers in Region

The following Markers overlap with this region.

RGD ID

Symbol

Expected Size

Chr

Start

Stop

Species

Match

Position Markers

Peak: (D8Rat59)

Rat Assembly	Chr	Position (strand)	Source
Rnor_5.0	8	115,112,735 - 115,113,003	NCBI
RGSC_v3.4	8	112,242,639 - 112,242,906	RGD
RGSC_v3.1	8	112,262,094 - 112,262,361	RGD
RH 3.4 Map	8	1127.5	UniSTS
RH 3.4 Map	8	1127.5	RGD
RH 2.0 Map	8	872.8	RGD
SHRSP x BN Map	8	71.0	RGD
FHH x ACI Map	8	79.01	RGD

Additional Information

RGD Curation Notes

Note Type	Note	Reference
qtl_general	number of animals used: 5-6 months old 266 F₂ rats	1299960
qtl_general	measurement method: polyethylene catheters were inserted in the carotid artery and blood was drawn	1299960
qtl_general	software used: one-way analysis of variance (ANOVA)	1299960

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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QTL: Scl33 (Serum cholesterol QTL 33) Rattus norvegicus