Insul18 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Insul18 (Insulin level QTL 18) Rattus norvegicus

Symbol: Insul18
Name: Insulin level QTL 18
RGD ID: 6480780
Previously known as: Fasting Insulin
Trait: blood insulin amount   (VT:0001560)    
Measurement Type: plasma insulin level   (CMO:0000342)    
LOD Score: 4.11
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21189,607,473 - 200,611,765RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01206,950,905 - 218,614,387RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01218,337,839 - 225,482,294RGDRnor5.0
RGSC_v3.41198,853,034 - 205,897,680RGDRGSC3.4
Cross Type: Not Available
Strains Crossed: NMcwi:HS 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Tpcn2 is a candidate Gene for Insul18

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition
fasting  (IDA)

Measurement Method

Vertebrate Trait

Rat Strain
NMcwi:HS  (IEA)

References

References - curated
# Reference Title Reference Citation
1. QTLs registered by Dr. Solberg Woods Personal communication between Dr. Leah Solberg Woods and the RGD curators.
2. Fine-mapping diabetes-related traits, including insulin resistance, in heterogeneous stock rats. Solberg Woods LC, etal., Physiol Genomics. 2012 Sep 4.
3. Identification of a novel gene for diabetic traits in rats, mice, and humans. Tsaih SW, etal., Genetics. 2014 Sep;198(1):17-29. doi: 10.1534/genetics.114.162982.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
3643Sctsecretin1196382857196383668Rat
2775H19H19 imprinted maternally expressed transcript1197730698197733374Rat
69332Ifitm2interferon induced transmembrane protein 21196051539196052719Rat
69414Glrx3glutaredoxin 31192241707192272012Rat
71015Ap2a2adaptor related protein complex 2 subunit alpha 21196652315196725609Rat
2870Igf2insulin-like growth factor 21197814409197831802Rat
69330Echs1enoyl-CoA hydratase, short chain 11194895036194903863Rat
2827HrasHRas proto-oncogene, GTPase1196290127196299823Rat
3087MgmtO-6-methylguanine-DNA methyltransferase1191710980191937760Rat
61876Prap1proline-rich acidic protein 11194883078194886874Rat
3123Muc2mucin 2, oligomeric mucus/gel-forming1196799494196831740Rat
2386Cox8bcytochrome c oxidase, subunit VIIIb1195977183195978643Rat
2396Cpt1acarnitine palmitoyltransferase 1A1200564634200627059Rat
2315Cd81Cd81 molecule1198235861198251660Rat
71051Bet1lBet1 golgi vesicular membrane trafficking protein-like1195931407195935072Rat
3853Thtyrosine hydroxylase1198071500198078832Rat
628826Muc6mucin 6, oligomeric mucus/gel-forming1196726678196764842Rat
628800Smim38small integral membrane protein 381200366561200371976Rat
727837Or6f2olfactory receptor family 6 subfamily F member 21194976929194977864Rat
621503Kcnq1potassium voltage-gated channel subfamily Q member 11198291711198624683Rat
621739Foxi2forkhead box I21190222857190226657Rat
68343Mrpl23mitochondrial ribosomal protein L231197687452197695222Rat
2522Drd4dopamine receptor D41196396366196400824Rat
620932Msx3msh homeobox 31194839041194842209Rat
621398Rnh1ribonuclease/angiogenin inhibitor 11196269293196281763Rat
628772Shank2SH3 and multiple ankyrin repeat domains 21199146210199590962Rat
628700FaddFas associated via death domain1199743200199745746Rat
62001Muc5acmucin 5AC, oligomeric mucus/gel-forming1196864336196896475Rat
68325Ighmbp2immunoglobulin mu DNA binding protein 21200506641200529293Rat
708478MrgprfMAS related GPR family member F1200464100200473588Rat
621511Ctsdcathepsin D1197527467197539343Rat
621719Calycalcyon neuron-specific vesicular protein1194862671194873861Rat
2916Ins2insulin 21197843277197992522Rat
68399Syt8synaptotagmin 81197588126197593598Rat
619839Cttncortactin1199599710199635254Rat
620771Ptpreprotein tyrosine phosphatase, receptor type, E1190344331190494815Rat
708549Nlrp6NLR family, pyrin domain containing 61196004854196011615Rat
620671Deaf1DEAF1 transcription factor1196401857196435541Rat
68384Ccnd1cyclin D11200089002200098524Rat
621769Dhcr77-dehydrocholesterol reductase1199015081199031055Rat
727892Cdkn1ccyclin-dependent kinase inhibitor 1C1198655394198658097Rat
62050Tnni2troponin I2, fast skeletal type1197595012197597554Rat
1304836Gatd1glutamine amidotransferase class 1 domain containing 11196504533196512561Rat
620126Fgf3fibroblast growth factor 31200001162200005539Rat
3883Tnnt3troponin T3, fast skeletal type1197652535197669736Rat
1304956Ebf3EBF transcription factor 31191996726192114593Rat
621290Cd151CD151 molecule (Raph blood group)1196564744196568753Rat
620800Bnip3BCL2 interacting protein 31193708164193725348Rat
621775Rplp2ribosomal protein lateral stalk subunit P21196546086196548636Rat
620674Taldo1transaldolase 11196493634196503965Rat
2475Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 11195840330195850728Rat
2193Bc1brain cytoplasmic RNA 11200073610200073763Rat
727801Nadsyn1NAD synthetase 11198981559199009853Rat
620504Cdhr5cadherin-related family member 51196373110196381609Rat
1304637Lto1LTO1 maturation factor of ABCE11200074247200080951Rat
1306015Pgghgprotein-glucosylgalactosylhydroxylysine glucosidase1196038276196044561Rat
1306133Lsp1lymphocyte-specific protein 11197614677197648414Rat
1304718Ifitm6interferon induced transmembrane protein 61196117043196118315Rat
1305864Stk32cserine/threonine kinase 32C1193900718193981723Rat
1305043Clrn3clarin 31190319025190334648Rat
1306425Dusp8dual specificity phosphatase 81197167392197184285Rat
1307601Ifitm1interferon induced transmembrane protein 11196067163196069169Rat
1305810Tspan4tetraspanin 41196571307196593842Rat
1304755Phlda2pleckstrin homology-like domain, family A, member 21198696897198699292Rat
1306732Sigirrsingle Ig and TIR domain containing1196195363196208692Rat
2159Ascl2achaete-scute family bHLH transcription factor 21198148999198151406Rat
738040MrgprdMAS related GPR family member D1200479204200487902Rat
738044MrgprgMAS related GPR family member G1198947648198951556Rat
738045MrgpreMAS related GPR family member E1198963786198969862Rat
1307378Scart1scavenger receptor family member expressed on T-cells 11195020750195031807Rat
620127Fgf4fibroblast growth factor 41200023937200027793Rat
1310028Cimap1aciliary microtubule associated protein 1A1195926034195929250Rat
1305391Nap1l4nucleosome assembly protein 1-like 41198709697198746093Rat
1307043Tssc4tumor suppressing subtransferable candidate 41198251986198254810Rat
1307439Lmntd2lamin tail domain containing 21196315112196320880Rat
620166Fgf19fibroblast growth factor 191200056526200060980Rat
708360Phrf1PHD and ring finger domains 11196333663196366901Rat
2409Dpysl4dihydropyrimidinase-like 41193883039193898916Rat
1304676Tolliptoll interacting protein1196961585196984252Rat
1333372Or13a23olfactory receptor family 13 subfamily A member 231195517786195518718Rat
1333828Or13a19colfactory receptor family 13 subfamily A member 19C1195334233195335162Rat
1310203Mrpl21mitochondrial ribosomal protein L211200529416200542568Rat
1309133Pkp3plakophilin 31196187914196198843Rat
1308399Tmem80transmembrane protein 801196435999196444368Rat
1307280Nkx6-2NK6 homeobox 21194380149194383533Rat
1560565Ano9anoctamin 91196208863196230381Rat
1333923Or12j4olfactory receptor family 12 subfamily J member 41195362981195363904Rat
1333513Or13a27dolfactory receptor family 13 subfamily A member 27D1195652234195653166Rat
1308402Osbpl5oxysterol binding protein-like 51198862071198916469Rat
1333199Or12j3olfactory receptor family 12 subfamily J member 31195264681195265604Rat
1333205Or13a25olfactory receptor family 13 subfamily A member 251195730853195731788Rat
1333083Or13o2-ps1olfactory receptor family 13 subfamily O member 2, pseudogene 11195188443195188890Rat
1332644Or13a27bolfactory receptor family 13 subfamily A member 27B1195393485195394417Rat
1333185Or12j2olfactory receptor family 12 subfamily J member 21195209804195210721Rat
1309693Tnfrsf26tumor necrosis factor receptor superfamily, member 261198802968198823032Rat
1334051Or12j2bolfactory receptor family 12 subfamily J member 2B1195315038195315949Rat
1333358Or6b13olfactory receptor family 6 subfamily B member 131195003659195004615Rat
1311779Tpcn2two pore segment channel 21200416538200446252Rat
1310786Ano1anoctamin 11199751439199900099Rat
1333221Or6ae1olfactory receptor family 6 subfamily A member E11194957151194958089Rat
1310747Cars1cysteinyl-tRNA synthetase 11198753689198796016Rat
1309044Pnpla2patatin-like phospholipase domain containing 21196552723196557805Rat
1333614Olr301-psolfactory receptor pseudogene 3011195366554195367209Rat
1332754Or13a26colfactory receptor family 13 subfamily A member 26C1195702019195702951Rat
1308374Sirt3sirtuin 31195942066195964472Rat
1310912Eps8l2EPS8-like 21196446260196471544Rat
1309009Ppfia1PTPRF interacting protein alpha 11199641277199718371Rat
1307914Ptdss2phosphatidylserine synthase 21196241439196267632Rat
1333353Or13a26olfactory receptor family 13 subfamily A member 261195779448195780380Rat
1311654Lrrc56leucine rich repeat containing 561196299843196315170Rat
1306168Inpp5ainositol polyphosphate-5-phosphatase A1194190086194380429Rat
1305236Psmd13proteasome 26S subunit, non-ATPase 131195964617195976895Rat
1310620Trpm5transient receptor potential cation channel, subfamily M, member 51198254956198277824Rat
1308721Tspan32tetraspanin 321198190128198204447Rat
1309401Cend1cell cycle exit and neuronal differentiation 11196525153196528152Rat
1306244Rassf7Ras association domain family member 71196319600196323787Rat
1307826Slc25a22solute carrier family 25 member 221196528471196536398Rat
1307828Irf7interferon regulatory factor 71196367380196370943Rat
1308241Adgra1adhesion G protein-coupled receptor A11194629744194673254Rat
708356Ppp2r2dprotein phosphatase 2, regulatory subunit B, delta1193665918193700277Rat
1307177Jakmip3janus kinase and microtubule interacting protein 31193753134193881105Rat
1307108Pwwp2bPWWP domain containing 2B1194040395194059979Rat
1309350Urahurate (5-hydroxyiso-) hydrolase1195905763195909159Rat
1333124Or13a18olfactory receptor family 13 subfamily A member 181195492445195493377Rat
1305476Mki67marker of proliferation Ki-671190496319190522983Rat
1333429Olr294-psolfactory receptor pseudogene 2941195229270195230031Rat
1308955Chid1chitinase domain containing 11196594357196629700Rat
1307900Ifitm5interferon induced transmembrane protein 51196045836196052554Rat
1308585Zfp511zinc finger protein 5111194817697194822102Rat
1309597Tubgcp2tubulin gamma complex component 21194791113194817807Rat
1310052B4galnt4beta-1,4-N-acetyl-galactosaminyl transferase 41196171394196182294Rat
1333577Or13a27olfactory receptor family 13 subfamily A member 271195235583195236515Rat
1561432Scgb1c1secretoglobin, family 1C, member 11195922660195925022Rat
1563319Ifitm10interferon induced transmembrane protein 101197507501197524180Rat
1562011Mrgprgl1MAS related GPR family member G like 11198937757198938662Rat
1561983Muc5bmucin 5B, oligomeric mucus/gel-forming1196916861196948830Rat
1560911Cracr2bcalcium release activated channel regulator 2B1196558407196563961Rat
1561125Paoxpolyamine oxidase1194919655194928498Rat
1561845Sprnshadow of prion protein1194944602194948448Rat
1562983Mob2MOB kinase activator 21197092991197149978Rat
1334251Or13a27eolfactory receptor family 13 subfamily A member 27E1195639216195640148Rat
1333730Or12j5olfactory receptor family 12 subfamily J member 51195417480195418403Rat
1333778Olr293-psolfactory receptor pseudogene 2931195220868195221101Rat
727957Ric8aRIC8 guanine nucleotide exchange factor A1195935162195941469Rat
1559853Syce1synaptonemal complex central element protein 11195852171195863174Rat
1334140Olr296-psolfactory receptor pseudogene 2961195260637195260964Rat
1334099Or13a26bolfactory receptor family 13 subfamily A member 26B1195754003195754938Rat
1559981Lrrc27leucine rich repeat containing 271194004967194035087Rat
1311186Fuomfucose mutarotase1194888535194893046Rat
1334329Olr314-psolfactory receptor pseudogene 3141195766783195767129Rat
1334216Or13a18bolfactory receptor family 13 subfamily A member 18B1195581371195582303Rat
1333032Or13a18colfactory receptor family 13 subfamily A member 18C1195610776195611708Rat
1332957Or13a27colfactory receptor family 13 subfamily A member 27C1195454589195455521Rat
1311792Pidd1p53-induced death domain protein 11196536815196542808Rat
1303323Slc22a18solute carrier family 22, member 181198670626198694977Rat
1333302Or13a19bolfactory receptor family 13 subfamily A member 19B1195160617195161546Rat
1559985Cfap46cilia and flagella associated protein 461194403212194482790Rat
1566256Brsk2BR serine/threonine kinase 21197035505197088624Rat
1565431Mapk1ip1mitogen-activated protein kinase 1 interacting protein 11193655319193665817Rat
1566394Adam8ADAM metallopeptidase domain 81194776559194789330Rat
1586688Tnfrsf22tumor necrosis factor receptor superfamily, member 221198840452198860713Rat
1562437Tcerg1ltranscription elongation regulator 1-like1193012937193201860Rat
1559948Sec61g-ps3Sec61 translocon subunit gamma, pseudogene 31195892846195913494Rat
1566209Polr2lRNA polymerase II, I and III subunit L1196570051196572060Rat
1565261Kndc1kinase non-catalytic C-lobe domain containing 11194689962194738353Rat
1566072Dock1dedicator of cyto-kinesis 11189467143189983777Rat
1588225Nt5c3a-ps15'-nucleotidase, cytosolic IIIA, pseudogene 11194832479194833350Rat
1598059Vmp1-ps1vacuole membrane protein 1, pseudogene 11195863294195875733Rat
1592604Krtap5-8keratin associated protein 5-81197446125197446817Rat
1589375Utf1undifferentiated embryonic cell transcription factor 11194740339194741465Rat
1592568Prr33proline rich 331197644903197650774Rat
1595844Ifitm3interferon induced transmembrane protein 31196111026196112135Rat
2302685Insyn2ainhibitory synaptic factor 2A1189697856189753194Rat
2314879Mir483microRNA 4831197818396197818468Rat
2314883Mir675microRNA 6751197732275197732358Rat
2314887Mir210microRNA 2101196326343196326452Rat
2318344C1h10orf143similar to human chromosome 10 open reading frame 1431192184440192222676Rat
2320863Kctd18-ps1potassium channel tetramerization domain containing 18, pseudogene 11197301146197302301Rat
2321900Or13a19olfactory receptor family 13 subfamily A member 191195196027195196956Rat
2322689Ncl-ps6nucleolin, pseudogene 61192181207192182026Rat
4888587Mir3574microRNA 35741196326337196326454Rat
2325486Mir202microRNA 2021194754730194754801Rat
2324597Npsneuropeptide S1190077040190080821Rat
6501977LOC100909737uncharacterized LOC1009097371197828893197830951Rat
6497155Mtg1mitochondrial ribosome-associated GTPase 11194931543194944278Rat
7506405LOC102552318actin-like1199035831199062916Rat
7498653LOC102552864uncharacterized LOC1025528641192580494192600465Rat
7536919LOC102552565uncharacterized LOC1025525651191966309191986518Rat
7646072LOC102553731uncharacterized LOC1025537311194746246194748946Rat
7556971LOC102552971uncharacterized LOC1025529711196232907196236176Rat
7553817LOC102553541uncharacterized LOC1025535411193731097193739373Rat
7694619LOC102552157uncharacterized LOC1025521571191017034191039381Rat
7684888LOC102551319uncharacterized LOC1025513191194845214194857999Rat
7725240LOC102551963uncharacterized LOC1025519631190441582190458258Rat
7669488LOC102548505uncharacterized LOC1025485051197705332197782594Rat
7670186LOC102553043uncharacterized LOC1025530431196325398196329434Rat
7744082LOC102551753uncharacterized LOC1025517531190139001190144141Rat
7711326LOC102548568vegetative cell wall protein gp1-like1197830951197834453Rat
9271178LOC103691261sperm flagellar protein 1-like1194769043194776455Rat
9278179Krtap5-1keratin associated protein 5-11197278886197279893Rat
9254028Krtap5-2-ps1keratin associated protein 5-2, pseudogene 11197288058197296467Rat
9257184Mrpl42-ps1mitochondrial ribosomal protein L42, pseudogene 11195068326195071518Rat
9439981LOC103691254ubiquitin-conjugating enzyme E2 L3 pseudogene1189951742189954254Rat
9453410LOC10369126360S ribosomal protein L9 pseudogene1195891303195891917Rat
11446129LOC108349660uncharacterized LOC1083496601190980953191004779Rat
11455008LOC108349678uncharacterized LOC1083496781200007802200018418Rat
11406967LOC108349665uncharacterized LOC1083496651193747619193751382Rat
11418059LOC108349679uncharacterized LOC1083496791200210221200234295Rat
11423318LOC108349659uncharacterized LOC1083496591191039559191041522Rat
11378084LOC108349673uncharacterized LOC1083496731197950020197994765Rat
11391312LOC108349862serine/arginine-rich splicing factor 3 pseudogene1195375344195375899Rat
11497536LOC10834967660S ribosomal protein L7a pseudogene1199684456199685258Rat
11497852LOC108348748small EDRK-rich factor 2 pseudogene1196162790196162970Rat
11491806Krtap5-5l1keratin associated protein 5-5 like 11197240382197241310Rat
41115869LOC120100190U6 spliceosomal RNA1196288031196288126Rat
41286380LOC120099968uncharacterized LOC1200999681200250061200268329Rat
41387290LOC120099954uncharacterized LOC1200999541194005130194006623Rat
41260372Krtap5-2keratin associated protein 5-21197266811197267905Rat
41187783LOC120099963uncharacterized LOC1200999631198355931198361600Rat
41331186Ncl-ps4nucleolin, pseudogene 41192178482192179369Rat
41150368LOC120093064scavenger receptor cysteine-rich domain-containing protein SCART1-like1195080285195136263Rat
41343059LOC120100426small nucleolar RNA SNORA171189941598189941726Rat
41194153Rnu6-81RNA, U6 small nuclear 811197577435197577542Rat
41370837LOC120097360uncharacterized LOC1200973601196090054196095217Rat
41127609LOC120098072uncharacterized LOC1200980721193366019193373317Rat
41196423Trnav-aac16transfer RNA valine (anticodon AAC) 161198797943198798023Rat
41220009LOC120098066uncharacterized LOC1200980661192488566192490563Rat
41348681LOC120099955uncharacterized LOC1200999551194433583194434401Rat
41399316LOC120099949uncharacterized LOC1200999491191146405191161742Rat
41399942Rps10-ps18ribosomal protein S10, pseudogene 181200084281200084735Rat
41071816LOC120099969uncharacterized LOC1200999691200344504200353691Rat
41349421Krtap5-5l2keratin associated protein 5-5 like 21197306627197307614Rat
41081613Snora54small nucleolar RNA, H/ACA box 541198727462198727588Rat
41230723LOC120099950uncharacterized LOC1200999501192233692192242528Rat
41165200LOC120099962uncharacterized LOC1200999621198493894198507093Rat
41015854LOC120099951uncharacterized LOC1200999511192977453192980548Rat
40974632LOC120099966uncharacterized LOC1200999661200101019200131295Rat
40975851LOC120097361uncharacterized LOC1200973611196153056196157337Rat
41341459LOC120099959uncharacterized LOC1200999591198077644198123085Rat
40983107Rnu6-1205RNA, U6 small nuclear 12051196216573196216678Rat
40988177LOC12009995760S ribosomal protein L36-like1194805628194806244Rat
41074861LOC120099952uncharacterized LOC1200999521192968015192975350Rat
41242081LOC120099961uncharacterized LOC1200999611198441954198492524Rat
41246513LOC120097362uncharacterized LOC1200973621196635648196645020Rat
41029299LOC120099956uncharacterized LOC1200999561194753901194762856Rat
41079295LOC12009996460S ribosomal protein L21-like1199147655199158744Rat
41319684LOC120098076uncharacterized LOC1200980761194539061194544413Rat
41029618LOC120097363uncharacterized LOC1200973631196704589196707241Rat
41136023LOC120099953uncharacterized LOC1200999531193711614193714736Rat
41338033LOC120097365uncharacterized LOC1200973651197546933197550986Rat
41257465LOC120098479scavenger receptor cysteine-rich domain-containing protein SCART1-like1195039124195041676Rat
41223125LOC120099958uncharacterized LOC1200999581195841002195844138Rat
41303933Snora52small nucleolar RNA, H/ACA box 521196547488196547621Rat
41066460LOC120100392small nucleolar RNA SNORA511195788436195788564Rat
41238308LOC120099967uncharacterized LOC1200999671200189261200203943Rat
41069559Rnu6-317RNA, U6 small nuclear 3171196649599196649705Rat
41044945LOC120099960uncharacterized LOC1200999601198173459198179646Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10450D1Smu42401195841852195842092Ratregion
10768D1Wox221301197816378197816499Ratregion
10769D1Arb242591197816307197816572Ratregion
33878D1Mit271951198211513198211706Ratregion
34021D1Mit282121193422268193422481Ratregion
34244D1Mgh101381199050459199050587Ratregion
34326D1Mgh211501192485903192486075Ratregion
34703D1Mgh311341196302015196302141Ratregion
11413D1Smu31011198081083198081184Ratregion
11435D1Arb233001197655883197656196Ratregion
33753D1Mit51651197697768197697933Ratregion
36239D1Rat1111521197260913197261052Ratregion
37294D1Rat1331621192825098192825253Ratregion
35204D1Rat3671601197898742197898893Ratregion
35204D1Rat3671601197933504197933671Ratregion
37120D1Rat1281121193133375193133485Ratregion
37732D1Rat2082171191019702191019931Ratregion
36460D1Rat691621194129394194129561Ratregion
35615D1Rat701521199773958199774075Ratregion
38086D1Rat1441161193630368193630488Ratregion
38222D1Rat2181711196051950196052123Ratregion
40534D1Rat2911671195109528195109710Ratregion
40700D1Rat2902061190292090190292292Ratregion
38570D1Rat2402411193113876193114096Ratregion
38638D1Rat1522271194979407194979626Ratregion
38650D1Rat1652131192731695192731896Ratregion
38738D5Rat1122001192144133192144333Ratregion
38854D1Rat1682091199368955199369166Ratregion
38940D1Rat1592001193810285193810478Ratregion
38954D1Rat1812161197670404197670618Ratregion
39152D1Rat1472111190409744190409955Ratregion
39462D1Rat2892051191277928191278129Ratregion
42069D1Arb221781193207204193207417Ratregion
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5502655AI1182251211194926911194928192Ratregion
5503029MARC_54883-54884:1155673702:101198657463198658048Ratregion
5503476UniSTS:4626872541197843339197844092Ratregion
5503625UniSTS:4653962971198472540198472837Ratregion
5507537REN1159132601197592163197592423Ratregion
5507606Ccnd11671200091848200093446Ratregion
5507608Cdkn1c01198656296198657287Ratregion
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5504744PMC86690P14211196298701196299122Ratregion
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5505071Cdkn1c1931198657094198657287Ratregion
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5506513UniSTS:276141851197819139197819224Ratregion
5507141UniSTS:2248221691191937768191937937Ratregion
5500989PMC112649P21971196298157196298354Ratregion
5500995PMC114617P210221196368918196369940Ratregion
5501730UniSTS:2670032181197843338197844055Ratregion
550015702.MMHAP94FRA8.seq6631200389913200390576Ratregion
5499959UniSTS:2358063691194945478194945847Ratregion
5499963UniSTS:2357992821193655928193656210Ratregion
5499965UniSTS:2358162001198149023198149223Ratregion
5499897UniSTS:23534001198866212198867552Ratregion
5500479Osbp2-pending9991198880142198881141Ratregion
5500501RH1265962101199599777199599987Ratregion
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5501339ECD217422331197821931197822164Ratregion
5501389Ascl22371198150162198150399Ratregion
5501453Th11301198075568198076698Ratregion
5501644UniSTS:2654591631197730830197730993Ratregion
5503896Osbpl59941198880142198881136Ratregion
5504584PMC309645P22561197832788197833044Ratregion
5505020Igf21341197817882197819233Ratregion
5501650UniSTS:2654866051198656918198657523Ratregion
5501652UniSTS:2654912511197731147197731509Ratregion
5501654UniSTS:2654926071197730743197731461Ratregion
5501657PMC24644P61881197843343197844030Ratregion
5501716Dusp815771197169887197171464Ratregion
5506191UniSTS:4987568791197527747197529055Ratregion
5502226Fgf411781200024265200025443Ratregion
5506759G452222291194938242194938471Ratregion
5502301RH1243431961196362884196363080Ratregion
Position Markers

Flank 1: (D1Rat129)
Rat AssemblyChrPosition (strand)Source
Rnor_5.01218,337,839 - 218,338,087NCBI
RGSC_v3.41198,853,034 - 198,853,281RGD
RGSC_v3.11199,003,017 - 199,003,326RGD
RH 3.4 Map11437.9UniSTS
RH 3.4 Map11437.9RGD
SHRSP x BN Map1101.4699RGD
SHRSP x BN Map1101.4699UniSTS
Peak: (D1Rat291)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21195,109,528 - 195,109,710 (+)MAPPER
Rnor_6.01212,782,556 - 212,782,737NCBI
Rnor_5.01219,697,659 - 219,697,840UniSTS
RGSC_v3.41200,166,700 - 200,166,881UniSTS
RGSC_v3.41200,166,700 - 200,166,881RGD
RGSC_v3.11200,316,692 - 200,316,873RGD
SHRSP x BN Map1101.4699UniSTS
SHRSP x BN Map1101.4699RGD
FHH x ACI Map195.53RGD
Cytogenetic Map1q41UniSTS
Flank 2: (D1Got189)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21200,611,501 - 200,611,765 (+)MAPPER
Rnor_6.01218,614,124 - 218,614,387NCBI
Rnor_5.01225,482,031 - 225,482,294UniSTS
RGSC_v3.41205,897,416 - 205,897,680RGD
RGSC_v3.41205,897,417 - 205,897,680UniSTS
RGSC_v3.11206,050,870 - 206,051,133RGD
Celera1198,166,955 - 198,167,218UniSTS
RH 3.4 Map11560.5UniSTS
RH 3.4 Map11560.5RGD
RH 2.0 Map11113.7RGD
Cytogenetic Map1q43UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144017057197814409Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1151162512201278233Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512201278233Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1151162512201278233Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1151646613196646613Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1154561505199561505Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1155866514200866514Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1156677124201278233Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1158633083203633083Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393213533942Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164747424209747424Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1164747424209747424Rat
2312558Glom17Glomerulus QTL 173.90.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1166532971191278129Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169112897197261052Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1169112897197261052Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169537671214537671Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1169537671214537671Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1171310381216310381Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1171629477216629477Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1171629477216629477Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1171629477216629477Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1171629477216629477Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1171629477216629477Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1172609619217609619Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1173108781218108781Rat
631670Iddm10Insulin dependent diabetes mellitus QTL 101.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1174133260196383668Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1174133260219133260Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1176550523221550523Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1176869060221869060Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
1558658Bw59Body weight QTL 593.50.0003body mass (VT:0001259)body weight (CMO:0000012)1178784622223784622Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1302787Stl25Serum triglyceride level QTL 252.70.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1180359209210702199Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1180359209218108781Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1181133855226133855Rat
61378Bp43Blood pressure QTL 4322.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1181746937196383668Rat
724559Pancm1Pancreatic morphology QTL 17.1islet of Langerhans morphology trait (VT:0005215)pancreatic islet damage composite score (CMO:0001156)1181759564214537555Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1181829673224569684Rat
634312Bp143Blood pressure QTL 14330.0002arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1182623426219932796Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1183970203243914901Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1183970203243914901Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1184550676229550676Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1185145134221264292Rat
1359018Hrtrt20Heart rate QTL 203.08heart pumping trait (VT:2000009)heart rate (CMO:0000002)1185356336202902618Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1185356336231689108Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1188377360224054420Rat
6480780Insul18Insulin level QTL 184.11blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1189607473200611765Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1191019702246062233Rat
10059590Kidm44Kidney mass QTL 443.420.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1191033875236033875Rat
631260Tcas2Tongue tumor susceptibility QTL 24.93tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)1192485903199050587Rat
1358191Ept10Estrogen-induced pituitary tumorigenesis QTL 103.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)1192825253243914732Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1193113876238113876Rat
634338Hcar4Hepatocarcinoma resistance QTL 44.6liver integrity trait (VT:0010547)liver tumorous lesion number to liver area ratio (CMO:0001210)1193422268214537671Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1196248093241248093Rat
1358292Cm37Cardiac mass QTL 376.20.00000081heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1196248093241248093Rat
6480777Insul17Insulin level QTL 173.86blood insulin amount (VT:0001560)blood insulin level area under curve (AUC) (CMO:0000351)1197260913198211706Rat
6480783Insul19Insulin level QTL 194.33blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1197489281200611765Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1197670404242670404Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1197697768238755659Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1197814409242814409Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1197814409242814409Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
1331790Bp201Blood pressure QTL 2013.127arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1198211513225126682Rat
6480773Gluco64Glucose level QTL 645.09blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459200611765Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1199368955224569684Rat
2314011Gluco56Glucose level QTL 56blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1199773958202166723Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general measurement method:at 16 weeks of age animals were fasted overnight, blood samples were collected from the tail at 15, 30, 60, and 90 min after 1 g/kg body wt glucose injection; plasma insulin level was measured by the ELISA kit 6893578
qtl_general number of animals used: 10-21 male rats from the founders and 782 male NMcwi:HS rats 6893578
qtl_general software used:ANOVA 6893578
qtl_general sharp peak for expression of Tpcn2 was observed, there was a nonsynonymous amino acid change in F344, this negatively correlates to fasting glucose 9587420
qtl_map 200.17–201.13 Mb 6893578