Hcar5 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Hcar5 (Hepatocarcinoma resistance QTL 5) Rattus norvegicus

Symbol: Hcar5
Name: Hepatocarcinoma resistance QTL 5
RGD ID: 634340
Previously known as: Hcr5; Drh1b
Trait: liver integrity trait   (VT:0010547)    
Measurement Type: liver tumorous lesion number   (CMO:0001068)    
LOD Score: 8.0
P Value: Not Available
Variance: Not Available
Inheritance Type: recessive
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21214,537,555 - 226,660,468RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01236,763,415 - 247,065,599RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01244,066,294 - 254,305,341RGDRnor5.0
RGSC_v3.41220,639,539 - 232,579,992RGDRGSC3.4
RGSC_v3.11220,803,562 - 232,744,015RGD
Cross Type: intercross
Strains Crossed: F344/NRrrc DRH/Seac 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Cyp17a1 is a candidate Gene for Hcar5
Cyp2c11 is a candidate Gene for Hcar5

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Vertebrate Trait

Rat Strain
DRH/Seac  (IEA)
F344/NRrrc  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Resistance of DRH strain rats to chemical carcinogenesis of liver: genetic analysis of later progression stage. Yan Y, etal., Carcinogenesis 2002 Jan;23(1):189-96.
2. Genetic resistance to chemical carcinogen-induced preneoplastic hepatic lesions in DRH strain rats. Zeng ZZ, etal., Cancer Res 2000 Jun 1;60(11):2876-81.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2087Aldh1a1aldehyde dehydrogenase 1 family, member A11218000470218152962Rat
70934Klf9KLF transcription factor 91220700108220725029Rat
2118Anxa1annexin A11217861175217877205Rat
3963Vldlrvery low density lipoprotein receptor1224813539224850400Rat
619807Tjp2tight junction protein 21221709745221838383Rat
628849Ostf1osteoclast stimulating factor 11216002037216049250Rat
621716Foxd4forkhead box D41222557494222559189Rat
708495Zng1aZn regulated GTPase metalloprotein activator 1A1222568278222612937Rat
621640Dmrt1doublesex and mab-3 related transcription factor 11223142859223241333Rat
620252Aldh1a7aldehyde dehydrogenase family 1, subfamily A71218201443218241410Rat
621617Gdaguanine deaminase1218903045218982360Rat
620326Pcsk5proprotein convertase subtilisin/kexin type 51214837847215267626Rat
621370Gcnt1glucosaminyl (N-acetyl) transferase 11214718344214755735Rat
620844Apba1amyloid beta precursor protein binding family A member 11221363769221569496Rat
3696Slc1a1solute carrier family 1 member 11226549932226631925Rat
708369Ptar1protein prenyltransferase alpha subunit repeat containing 11221283306221326861Rat
1307524Entrep1endosomal transmembrane epsin interactor 11221592500221646603Rat
1304888Trpm3transient receptor potential cation channel, subfamily M, member 31219673200220557610Rat
1305129Mamdc2MAM domain containing 21220863959221016493Rat
1306043Dmrt3doublesex and mab-3 related transcription factor 31223244340223264254Rat
1302988Smarca2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 21224191125224358640Rat
1309942Trpm6transient receptor potential cation channel, subfamily M, member 61216136407216320523Rat
1307969Pgm5phosphoglucomutase 51222325638222513423Rat
1307779Rfx3regulatory factor X31225449872225709622Rat
1307492Smc5structural maintenance of chromosomes 51220769366220839138Rat
1306778RorbRAR-related orphan receptor B1216363629216544390Rat
1309271Kcnv2potassium voltage-gated channel modifier subfamily V member 21224999552225014062Rat
1308682Tmc1transmembrane channel-like 11218275262218445955Rat
1359349Tmem252transmembrane protein 2521222316982222321946Rat
1563931RGD1563931similar to basic transcription factor 31217554312217557717Rat
1311863Carnmt1carnosine N-methyltransferase 11216093720216123360Rat
1310776Zfand5zinc finger AN1-type containing 51218765735218776118Rat
1311350Prune2prune homolog 2 with BCH domain1214352586214624848Rat
1309047Dmrt2doublesex and mab-3 related transcription factor 21223317543223324131Rat
1359158C1h9orf85similar to human chromosome 9 open reading frame 851219136085219197723Rat
1310914Pip5k1bphosphatidylinositol-4-phosphate 5-kinase type 1 beta1221907220222183672Rat
1310316Pabir1PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 11222114988222116294Rat
1307714Kank1KN motif and ankyrin repeat domains 11222877962223074514Rat
1307941Cemip2cell migration inducing hyaluronidase 21219330295219407760Rat
1310039Spata6lspermatogenesis associated 6-like1226630470226682979Rat
1305246Abhd17babhydrolase domain containing 17B, depalmitoylase1219198294219232733Rat
1564753Pum3pumilio RNA-binding family member 31225074332225113995Rat
1560242Cfap95cilia and flagella associated protein 951221123786221242963Rat
1565754Fxnfrataxin1221874007221897841Rat
1563237C1h9orf40similar to human chromosome 9 open reading frame 401216128687216132896Rat
1561588Dock8dedicator of cytokinesis 81222649309222842474Rat
1562774Psmb6-ps1proteasome 20S subunit beta 6, pseudogene 11224033071224034353Rat
1549748Rfkriboflavin kinase1214799880214807440Rat
1564687Nmrk1nicotinamide riboside kinase 11216049350216076792Rat
1584793Rps11-ps3ribosomal protein S11, pseudogene 31219264217219264733Rat
1586523Ahcy-ps4adenosylhomocysteinase, pseudogene 41217020367217021658Rat
1565505Glis3GLIS family zinc finger 31225976029226395849Rat
1564433Gapdh-ps11Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 111221245734221249296Rat
1589453Ppid-ps2peptidylprolyl isomerase D, pseudogene 21225740072225741290Rat
1596834Hmgb1-ps4high-mobility group box 1, pseudogene 41222796925222798187Rat
1597038Rnps1-ps3RNA binding protein with serine rich domain 1, pseudogene 31215867429215868901Rat
2323439LOC100363201nucleophosmin 1-like1217543373217544186Rat
2323621Ran-ps1RAN, member RAS oncogene family, pseudogene 11223132286223132860Rat
2325551Mir204microRNA 2041220316931220317040Rat
2325049Eif4e-ps2eukaryotic translation initiation factor 4E, pseudogene 21225371014225371531Rat
6489406Timm23-ps3translocase of inner mitochondrial membrane 23, pseudogene 31219969156219980173Rat
6494111Aldoa-ps2aldolase, fructose-bisphosphate A, pseudogene 21217423560217425007Rat
6490675C1h9orf57similar to human chromosome 9 open reading frame 571219079683219084806Rat
6495932Rps17-ps1ribosomal protein S17, pseudogene 11224590238224590650Rat
7517961Thoc3-ps1THO complex 3, pseudogene 11225665659225666454Rat
7503291LOC102552001uncharacterized LOC1025520011220284052220295326Rat
7656472LOC102555714uncharacterized LOC1025557141224884342224938169Rat
7657219LOC102551351uncharacterized LOC1025513511218637961218681826Rat
7658951LOC102554959uncharacterized LOC1025549591216520876216525016Rat
7594231LOC102555110uncharacterized LOC1025551101223909032223923555Rat
7618157LOC102551544uncharacterized LOC1025515441218792565218797618Rat
7599954LOC102557104uncharacterized LOC1025571041224657115224660713Rat
7600426LOC102554752uncharacterized LOC1025547521222973015222980840Rat
7566943LOC102555989uncharacterized LOC1025559891225289547225334401Rat
7715694LOC102546345uncharacterized LOC1025463451226521231226549807Rat
7668904LOC102554711uncharacterized LOC1025547111216159777216162543Rat
7700759LOC102555808uncharacterized LOC1025558081225114347225140414Rat
7729455LOC102556915uncharacterized LOC1025569151222610724222638904Rat
9142228LOC103691306uncharacterized LOC1036913061218797024218823843Rat
9111077Fabp5-ps1fatty acid binding protein 5, pseudogene 11219250663219251166Rat
9160927LOC103695057uncharacterized LOC1036950571223944725223966152Rat
9327776LOC103691315uncharacterized LOC1036913151223712697223723908Rat
9453920LOC103691317uncharacterized LOC1036913171224095049224105835Rat
11474079LOC108349792glyceraldehyde-3-phosphate dehydrogenase pseudogene1216612021216613034Rat
11445681LOC108349100uncharacterized LOC1083491001220591633220623488Rat
11409422LOC108348917uncharacterized LOC1083489171224434444224436629Rat
11400155LOC108349212uncharacterized LOC1083492121223558078223568748Rat
11381164LOC108348948uncharacterized LOC1083489481219237610219250592Rat
11518304LOC108349823uncharacterized LOC1083498231220224951220261496Rat
11492063LOC108348874glyceraldehyde-3-phosphate dehydrogenase pseudogene1218714987218715999Rat
41111402LOC120100370small nucleolar RNA SNORA441218910326218910454Rat
41169281LOC120100001uncharacterized LOC1201000011219253161219254987Rat
41204295Rpl7a-ps5ribosomal protein L7a, pseudogene 51218756843218757810Rat
41205153LOC120100004uncharacterized LOC1201000041221677917221703867Rat
41277114Rnu6-525RNA, U6 small nuclear 5251226541765226541871Rat
41324627LOC120098080uncharacterized LOC1200980801214790533214793639Rat
41171153LOC120100363small nucleolar RNA SNORA241222808283222808414Rat
41278963LOC120100006uncharacterized LOC1201000061223632579223634200Rat
41142846LOC120098084uncharacterized LOC1200980841226451090226457544Rat
41207476LOC120100483small nucleolar RNA U131215255621215255715Rat
41092905Rnu6-1267RNA, U6 small nuclear 12671215294117215294226Rat
41211547LOC120100127U6 spliceosomal RNA1221643603221643709Rat
41332067LOC120100428small nucleolar RNA SNORA171219869292219869423Rat
41391465Rnu6-806RNA, U6 small nuclear 8061220856369220856475Rat
41097335LOC120100391small nucleolar RNA SNORA511225495834225495966Rat
41155325LOC120097452uncharacterized LOC1200974521220458818220461266Rat
41287817LOC120100498U4 spliceosomal RNA1221085628221085775Rat
41395459Trnap-agg60transfer RNA proline (anticodon AGG) 601223386056223386136Rat
41216261LOC120098083uncharacterized LOC1200980831224544345224550155Rat
41370285Eif4a1-ps7eukaryotic translation initiation factor 4A1, pseudogene 71219386631219389372Rat
41396975LOC120099997acyl-protein thioesterase 1-like1214772482214777313Rat
41102373LOC120100401small nucleolar RNA SNORA481221141990221142132Rat
41157562LOC120100414small nucleolar RNA SNORA171219114576219114705Rat
41219068LOC120100460small nucleolar RNA SNORA171221233213221233314Rat
41400972LOC120100007uncharacterized LOC1201000071224550777224558046Rat
41401218Rnu6-613RNA, U6 small nuclear 6131225971183225971289Rat
41377637LOC120100479U6atac minor spliceosomal RNA1225488774225488891Rat
41085563LOC120100429small nucleolar RNA SNORA171215798358215798482Rat
41166240LOC120100427small nucleolar RNA SNORA171216711164216711298Rat
41200944LOC120100005uncharacterized LOC1201000051221956410221958663Rat
40945859LOC120098082uncharacterized LOC1200980821221255188221260427Rat
40950760LOC120100009uncharacterized LOC1201000091224569800224574317Rat
40977760LOC120100011uncharacterized LOC1201000111224732926224747712Rat
40955348Rnu6-65RNA, U6 small nuclear 651221343294221343397Rat
40929454Rpl27a-ps11ribosomal protein L27a,pseudogene 111226599524226609228Rat
40930941Rps15-ps7ribosomal protein S15, pseudogene 71216059427216061856Rat
41004520LOC120100010uncharacterized LOC1201000101224677005224690946Rat
41047541LOC120100459small nucleolar RNA SNORA171219771021219771145Rat
41025384LOC120100008uncharacterized LOC1201000081224568140224570488Rat
41134905LOC120099999uncharacterized LOC1200999991216036346216042503Rat
41317889LOC120100013uncharacterized LOC1201000131226555109226567867Rat
41061241LOC120100000uncharacterized LOC1201000001218891154218910823Rat
41225190LOC12010000340S ribosomal protein S12-like1220574554220577707Rat
41303320LOC120098081uncharacterized LOC1200980811216690552216691985Rat
41065455Rpl29-ps10ribosomal protein L29, pseudogene 101215941677215978913Rat
41304355Dynlt1-ps1dynein light chain Tctex-type 1, pseudogene11222125549222133864Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
33945D1Mit181211218753689218753816Ratregion
34009D1Mit341241225126575225126682Ratregion
36219D1Rat3841651223390805223390953Ratregion
36866D1Rat731801218748008218748178Ratregion
36960D1Rat761441224569538224569684Ratregion
37162D1Rat721631219008538219008695Ratregion
37754D1Rat1231991218108584218108781Ratregion
37902D1Rat1691391224054293224054420Ratregion
37982D1Rat2232081222987545222987745Ratregion
35909D1Rat741811221264111221264292Ratregion
39560D1Rat3242021223506828223507030Ratregion
41168D1Rat2992271218972999218973225Ratregion
41392D1Rat3021591226660307226660468Ratregion
42527D1Rat3692441220461115220461370Ratregion
42528D1Rat4432051221012144221012343Ratregion
42529D1Rat4442841221701015221701306Ratregion
42530D1Rat4452251225436894225437098Ratregion
41036D1Rat2982071219932573219932796Ratregion
41048D1Rat2962461217206835217207077Ratregion
41806D1Rat3702311220165574220165798Ratregion
41882D1Rat4744321224262121224262540Ratregion
43423D1Got2281191225824951225825067Ratregion
43424D1Wox10901214537555214537671Ratregion
43426D1Got2311101225713778225713888Ratregion
43461D1Got2231481222435979222436124Ratregion
43605D1Got2221841220720366220720548Ratregion
60217D1Got2162481215510738215510986Ratregion
60219D1Got2192771218623671218623948Ratregion
60220D1Got2202291222265205222265431Ratregion
60221D1Got2212091221362223221362434Ratregion
60223D1Got2262071221665594221665801Ratregion
62489D1Uia72271217136594217136817Ratregion
66618D1Mco412901221919753221920075Ratregion
67776D1Uwm82431214737483214737720Ratregion
1629229D1Got341881219353990219354078Ratregion
1638953D1Got4372591222265486222265745Ratregion
1639509D1Wox861601219008044219008204Ratregion
1640039D1M19Mit128571214644917214644974Ratregion
1635618D1Got3773351224551772224552102Ratregion
1635712D1Got342901218038402218038492Ratregion
5039140RH1275351871219138335219138522Ratregion
5037073WI-203732221220726511220726733Ratregion
5031460AU0482502391220833136220833377Ratregion
5026524RH1325442201219195276219195496Ratregion
5029275RH1441791341220708998220709132Ratregion
5032163RH1259842301214569925214570155Ratregion
5029482D1Bda562181214838009214838227Ratregion
5029721BE0966852081225013066225013274Ratregion
5029727BE1021131621225495877225496039Ratregion
5032483D19Ertd744e2201220551196220551416Ratregion
5027157WI-187461491224845372224845521Ratregion
5032781RH1352771941225397248225397441Ratregion
5025266RH1276562061217861231217861437Ratregion
502784309.MMHAP31FLC3.seq1511224842817224842968Ratregion
5028057Results_ER_8_28_95_2_42.seq1881226018279226018467Ratregion
5030603BE1136451791219171782219171961Ratregion
5030725BE1077751521218779785218779937Ratregion
5030847BE1206671791219346780219346959Ratregion
5028316D9S19862761218775283218775559Ratregion
5051675RH945931871217861226217861413Ratregion
5057203D1Bda572081218152592218152800Ratregion
5057376AA851370991221914558221914657Ratregion
5054563RH1432961091219384105219384214Ratregion
5057788BE1015431751216468641216468816Ratregion
5058686BF3935221391221506666221506805Ratregion
5055969RH1441071711220556140220556311Ratregion
5058730BE1023961571216477175216477332Ratregion
5059656BF3941131811215994901215995082Ratregion
5057205D1Bda582541217861237217861491Ratregion
5055207RH1436681601217876465217876625Ratregion
5059112BE1028511921220488174220488366Ratregion
5053349RH1425972351220772000220773196Ratregion
5051743RH946331791218152697218152876Ratregion
5045134RH1310032201218900833218901053Ratregion
5045636RH1312911961216132603216132799Ratregion
5044202RH1304681831222253136222253319Ratregion
5048706RH1330581861222928444222928630Ratregion
5044302RH1305251841226631740226631924Ratregion
5046470RH1317711701220560535220560705Ratregion
5047690RH1324721931222638513222638706Ratregion
5047780RH1325241971221774547221774744Ratregion
5046608RH1318511911216356958216357149Ratregion
5046786RH1319541861218043367218043553Ratregion
5048052RH1326802191218765210218765429Ratregion
5047072RH1321181971224849997224850194Ratregion
5048252RH1327961881221709826221710014Ratregion
5048518RH1329492181218902533218902751Ratregion
5039994RH1280271801214807123214807303Ratregion
5042762RH1296311851217861215217861400Ratregion
5042808RH1296581801218903235218903415Ratregion
5041928RH1291401501214806001214806151Ratregion
5043816RH1302442081214569913214570121Ratregion
5041550RH1289211821221592548221592730Ratregion
5075418RH1385821401225013448225013588Ratregion
5076028RH1389371721214623605214623780Ratregion
5076296RH1390932121222558809222559021Ratregion
5076908RH1394481241219136217219136341Ratregion
5080562RH1416512061221334766221334972Ratregion
5075576RH1386731201216123153216123273Ratregion
5077546RH1398181941218777868218778062Ratregion
5077162RH1395981891223365706223365895Ratregion
5077256RH1396521991222321588222321787Ratregion
5079870RH1412512081223075751223075959Ratregion
5078900RH1406172201216745395216745615Ratregion
5078460RH1403561661219406796219406962Ratregion
5073390RH1374082051225013851225014056Ratregion
5074152RH1378511971221336475221336672Ratregion
5073162RH1372751871218152663218152850Ratregion
5071822RH1353042051219811320219811525Ratregion
5071350RH1350311811220337603220337784Ratregion
5073584RH1375201521215113055215113207Ratregion
5065090BF4057861851220121237220121422Ratregion
5066984AU0480341491214763679214763828Ratregion
5067658AU0476131361226142736226142872Ratregion
5068284AU0472391381215637854215637992Ratregion
5070193RH945261081224845310224845416Ratregion
5070534AU0153942321220849691220849923Ratregion
5069266AU0466112991214826081214826374Ratregion
5063554BE1077882041220127904220128108Ratregion
5064056BE1205731531226629825226629978Ratregion
5060314AW5313571741218778492218778666Ratregion
5062964BE1135071931221322093221322286Ratregion
5064484BE1080611831220051657220051840Ratregion
5063280BI3016341581216733943216734101Ratregion
5064842BF3998451741226551852226552026Ratregion
5066454AU0483472311218826839218827070Ratregion
5061622BF4022961181222118725222118843Ratregion
5084314AI1693111271222321660222321787Ratregion
5087317BQ1953062021221874346221874548Ratregion
5082791BF3901181501222116991222117141Ratregion
5090675AU0498942621221130116221130378Ratregion
5084034AA9434361211224232526224232647Ratregion
5084208AA893933921222782207222782299Ratregion
5084658AA8514702201216110553216110773Ratregion
5082043BF4157731311220144561220144692Ratregion
5088609AU0486712671224206540224206807Ratregion
5080990RH1419001921222659472222659664Ratregion
5082637BF4164871471220472338220472485Ratregion
5084580AA9463752451220769832220770077Ratregion
5082939BF3904511681215029096215029264Ratregion
5081376AI0716341961222842145222842341Ratregion
5085282BM3900652161221982561221982777Ratregion
5081769BE1181401501225080480225080630Ratregion
5504205BARC00732191225740516225740721Ratregion
5505309Mlf26061221563065221563671Ratregion
5505075Dmrt11501223183780223183930Ratregion
5506911G478682881223295344223295632Ratregion
5500226AU0217211171218773608218774292Ratregion
5501618REN107D226321221069301221069933Ratregion
5502070MARC_26819-26820:1034280769:31101218770762218771451Ratregion
5501894MARC_16905-16906:1020714896:34581222593734222594192Ratregion
5502985D19Dcr4471214924277214924324Ratregion
5502319RH1244631391218773564218774270Ratregion
Position Markers

Flank 1: (D1Wox10)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21214,537,555 - 214,537,671 (-)MAPPER
Rnor_6.01236,763,415 - 236,763,528NCBI
Rnor_5.01244,066,294 - 244,066,407UniSTS
RGSC_v3.41220,639,539 - 220,639,653RGD
RGSC_v3.41220,639,540 - 220,639,653UniSTS
RGSC_v3.11220,803,562 - 220,803,676RGD
Celera1211,854,688 - 211,854,801UniSTS
RH 2.0 Map11183.9RGD
Cytogenetic Map1q43UniSTS
Flank 2: (D1Rat302)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21226,660,307 - 226,660,468 (+)MAPPER
Rnor_6.01247,065,439 - 247,065,599NCBI
Rnor_5.01254,305,181 - 254,305,341UniSTS
RGSC_v3.41232,579,831 - 232,579,992RGD
RGSC_v3.41232,579,832 - 232,579,992UniSTS
RGSC_v3.11232,743,855 - 232,744,015RGD
Celera1223,813,143 - 223,813,303UniSTS
RH 3.4 Map11608.6UniSTS
RH 3.4 Map11608.6RGD
SHRSP x BN Map1126.57UniSTS
SHRSP x BN Map1126.57RGD
Cytogenetic Map1q52UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642722214537671Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169537671214537671Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1169537671214537671Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1171310381216310381Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1171629477216629477Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1171629477216629477Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1171629477216629477Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1171629477216629477Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1171629477216629477Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1172609619217609619Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1173108781218108781Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1174133260219133260Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1176550523221550523Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1176869060221869060Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
1558658Bw59Body weight QTL 593.50.0003body mass (VT:0001259)body weight (CMO:0000012)1178784622223784622Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1180359209218108781Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1181133855226133855Rat
724559Pancm1Pancreatic morphology QTL 17.1islet of Langerhans morphology trait (VT:0005215)pancreatic islet damage composite score (CMO:0001156)1181759564214537555Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1181829673224569684Rat
634312Bp143Blood pressure QTL 14330.0002arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1182623426219932796Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1183970203243914901Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1183970203243914901Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1184550676229550676Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1185145134221264292Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1185356336231689108Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1188377360224054420Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1191019702246062233Rat
10059590Kidm44Kidney mass QTL 443.420.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1191033875236033875Rat
1358191Ept10Estrogen-induced pituitary tumorigenesis QTL 103.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)1192825253243914732Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1193113876238113876Rat
634338Hcar4Hepatocarcinoma resistance QTL 44.6liver integrity trait (VT:0010547)liver tumorous lesion number to liver area ratio (CMO:0001210)1193422268214537671Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1196248093241248093Rat
1358292Cm37Cardiac mass QTL 376.20.00000081heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1196248093241248093Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1197670404242670404Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1197697768238755659Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1197814409242814409Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1197814409242814409Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
1331790Bp201Blood pressure QTL 2013.127arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1198211513225126682Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1199368955224569684Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1201554356246554356Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1201554356246554356Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1201554356246554356Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1201554356246554356Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
10059587Bw173Body weight QTL 1733.230.025body mass (VT:0001259)body weight (CMO:0000012)1202069611247069611Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1203995416244113296Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1206081677251081677Rat
61403Niddm4Non-insulin dependent diabetes mellitus QTL 4blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1206329708222745518Rat
1357399Bw45Body weight QTL 453.05body mass (VT:0001259)body mass index (BMI) (CMO:0000105)1206329708251329708Rat
1357404Bw42Body weight QTL 424.490.0001body mass (VT:0001259)body weight (CMO:0000012)1206329708251329708Rat
1300168Bp170Blood pressure QTL 1702.76arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1207702246228581766Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1210702053240947965Rat
1358890Bp259Blood pressure QTL 2593.06arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1210702053260522016Rat
2292216Bw80Body weight QTL 803.230.0019body mass (VT:0001259)body weight (CMO:0000012)1213533809243914901Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1213707201252085212Rat
734768Niddm59Non-insulin dependent diabetes mellitus QTL 59body mass (VT:0001259)body weight (CMO:0000012)1213843987258843987Rat
634340Hcar5Hepatocarcinoma resistance QTL 58liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1214537555226660468Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1214537555238757011Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1214647894259647894Rat
1549910Bw54Body weight QTL 540.05body mass (VT:0001259)body weight (CMO:0000012)1214647894259647894Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1216255568260522016Rat
5508828Leukc3Leukocyte quantity QTL 3eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)1218108584224054420Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1218748008257976495Rat
61400Niddm1Non-insulin dependent diabetes mellitus QTL 111blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1218753689245907899Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1218753816256448513Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1221264111259647894Rat
10053715Scort24Serum corticosterone level QTL 242.130.0088blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1221414816260522016Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1222363780260522016Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1224054293243747962Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1224054293243747962Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1224054293260122809Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1224054293260122809Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1224569538260122809Rat
6480786Bw97Body weight QTL 975.03body mass (VT:0001259)body weight (CMO:0000012)1225126575227604520Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1225126575260522016Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Hcar5


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-04-14 Hcar5  Hepatocarcinoma resistance QTL 5  Hcr5    Symbol updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general this peak was also observed for GST-P mRNA levels at 20 weeks of 3'-Me-DAB treatment 625382