Scl67 QTL Report (Rattus norvegicus) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

QTL: Scl67 (Serum cholesterol level QTL 67) Rattus norvegicus

Symbol: Scl67
Name: Serum cholesterol level QTL 67
RGD ID: 631835
Previously known as: Dmo1; Niddm33; Non-insulin dependent diabetes mellitus QTL 33
Trait: blood cholesterol amount   (VT:0000180)    
Measurement Type: plasma total cholesterol level   (CMO:0000585)    
LOD Score: 4.27
P Value: 1.16E-5
Variance: 16.1
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01246,467,792 - 290,094,216RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41226,083,572 - 267,910,886RGDRGSC3.4
RGSC_v3.11226,343,481 - 268,121,971RGD
Cross Type: backcross
Strains Crossed: BN/SsNHsd OLETF/Got 



Candidate Gene Status
Ins1 is a candidate Gene for Scl67

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition
fasting  (IDA)

Measurement Method

Vertebrate Trait

Rat Strain
BN/SsNHsd  (IEA)
OLETF/Got  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Quantitative trait loci for lipid metabolism in the study of OLETF x (OLETF x Fischer 344) backcross rats. Yamasaki Y, etal., Clin Exp Pharmacol Physiol 2000 Nov;27(11):881-6.
Related QTLs

Related QTL Description Reference
Niddm45 interacts with RGD:619669
Bw115 interacts with RGD:619669
Bw116 maps to same region RGD:619669


Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Peak: (D1Rat306)
Rat AssemblyChrPosition (strand)Source
Rnor_5.01268,967,725 - 268,967,859NCBI
RGSC_v3.41248,583,506 - 248,583,639RGD
RGSC_v3.11248,843,278 - 248,843,684RGD
SHRSP x BN Map1135.6499RGD
SHRSP x BN Map1135.6499UniSTS


Additional Information

Database Acc Id Source(s)
NCBI Gene Niddm33


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-03-21 Scl67  Serum cholesterol level QTL 67  Niddm33  Non-insulin dependent diabetes mellitus QTL 33  Name updated 68913 APPROVED
2013-03-21 Scl67  Serum cholesterol level QTL 67  Niddm33  Non-insulin dependent diabetes mellitus QTL 33  Symbol updated 68687 APPROVED

RGD Curation Notes
Note Type Note Reference
qtl_cross_type backcross  
qtl_general syntenic to mouse chr 19 and human chr 10 619669
qtl_general LOD score of 3.8 is observed for plasma triglycerides and 2.39 for plasma non-esterified fatty acids 619669
qtl_general 95% confidence interval for plasma total cholesterol was 14.5 cM on either side of the peak marker 619669