Bp75 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Bp75 (Blood pressure QTL 75) Rattus norvegicus

Symbol: Bp75
Name: Blood pressure QTL 75
RGD ID: 631524
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: mean arterial blood pressure   (CMO:0000009)    
LOD Score: Not Available
P Value: 0.05
Variance: Not Available
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2161 - 110,831RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0161 - 778,655RGD_MAPPER_PIPELINERnor6.0
Rnor_5.016773,569 - 11,086,530RGDRnor5.0
RGSC_v3.41664,959 - 8,413,129RGDRGSC3.4
RGSC_v3.11664,959 - 8,413,127RGD
Cross Type: backcross
Strains Crossed: SS.LEW-(D16Mit2-D16Rat12)/Ayd SS.LEW-(D16Mit2-D16Chm23)/Ayd 
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations     Click to see Annotation Detail View
hypertension  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain


References - curated
# Reference Title Reference Citation
1. Combining congenic coverage with gene profiling in search of candidates for blood pressure quantitative trait loci in Dahl rats. Moujahidine M, etal., Hypertens Res 2004 Mar;27(3):203-12.
2. Congenic mapping of a blood pressure QTL on Chromosome 16 of Dahl rats. Moujahidine M, etal., Mamm Genome 2002 Mar;13(3):153-6.
Related QTLs

Related QTL Description Reference
Bp248 sub_region RGD:1300037


Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
621040Rps24ribosomal protein S24168953894267Rat
1305574Polr3aRNA polymerase III subunit A164917888178Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (D16Rat21)
Rat AssemblyChrPosition (strand)Source
Rnor_5.01611,086,530 - 11,086,707NCBI
RGSC_v3.4168,413,129 - 8,413,305RGD
RGSC_v3.1168,413,127 - 8,413,303RGD
RH 3.4 Map1681.6UniSTS
RH 3.4 Map1681.6RGD
FHH x ACI Map165.3799RGD
FHH x ACI Map165.3799UniSTS
Cytogenetic Map16 RGD
Flank 2: (D16Rat112)
Rat AssemblyChrPosition (strand)Source
mRatBN7.216110,590 - 110,831 (+)MAPPER
Rnor_6.016778,415 - 778,655NCBI
Rnor_5.016773,329 - 773,569UniSTS
RGSC_v3.41664,718 - 64,959RGD
RGSC_v3.41664,719 - 64,959UniSTS
RGSC_v3.11664,718 - 64,959RGD
Celera1697,314 - 97,554UniSTS
FHH x ACI Map160.0UniSTS
FHH x ACI Map160.0RGD

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631524Bp75Blood pressure QTL 750.05arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)161110831Rat
2325838Bp347Blood pressure QTL 3470.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1613080679Rat
1357403Slep4Serum leptin concentration QTL 43.91blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1619639137Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat

Additional Information

Database Acc Id Source(s)
NCBI Gene Bp75

RGD Curation Notes
Note Type Note Reference
qtl_cross_type backcross  
qtl_general associates with decreased blood pressures than that of the SS/Jr 70460
qtl_general the QTL was determined by the overlapped chromosomal segments of the two congenic strains 70460