Scl8 QTL Report (Rattus norvegicus)

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QTL Registration

General

QTL: Scl8 (Serum cholesterol level QTL8) Rattus norvegicus

Symbol:

Scl8

Name:

Serum cholesterol level QTL8

RGD ID:

631514

Trait:

blood cholesterol amount (VT:0000180)

Measurement Type:

serum total cholesterol level (CMO:0000363)

LOD Score:

4.4

P Value:

Not Available

Variance:

Not Available

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	2	231,621,666 - 266,435,125	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	2	250,313,889 - 285,068,071	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	2	224,795,742 - 258,207,540	RGD	RGSC3.4
RGSC_v3.1	2	224,810,349 - 258,222,147	RGD

Cross Type:

Not Available

Strains Crossed:

BC/CpbU LEW/OlaHsd

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

arteriosclerosis (IDA)

Hypercholesterolemia (IDA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

increased circulating cholesterol level (QTM)

Experimental Data Annotations Click to see Annotation Detail View

Clinical Measurement

serum total cholesterol level (IDA)

Experimental Condition

controlled cholesterol content diet (IDA)

controlled olive oil content diet (IDA)

fasting (IDA)

Measurement Method

enzymatic cholesterol assay (IDA)

Vertebrate Trait

blood cholesterol amount (IDA)

Rat Strain

BC/CpbU (IEA)

LEW/OlaHsd (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Quantitative trait loci influencing blood and liver cholesterol concentration in rats.	Bonne AC, etal., Arterioscler Thromb Vasc Biol 2002 Dec 1;22(12):2072-9.

Region

Markers in Region

The following Markers overlap with this region.

RGD ID

Symbol

Expected Size

Chr

Start

Stop

Species

Match

Position Markers

Peak: (D2Rat69)

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	254,121,593 - 254,121,739	NCBI
Rnor_5.0	2	272,813,816 - 272,813,962	UniSTS
RGSC_v3.4	2	247,295,669 - 247,295,816	RGD
RGSC_v3.4	2	247,295,670 - 247,295,816	UniSTS
RGSC_v3.1	2	247,310,276 - 247,310,423	RGD
Celera	2	229,879,373 - 229,879,519	UniSTS
RH 2.0 Map	2	1076.7	RGD
SHRSP x BN Map	2	106.7499	RGD
Cytogenetic Map	2	q45	UniSTS

Additional Information

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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QTL: Scl8 (Serum cholesterol level QTL8) Rattus norvegicus

Mammalian Phenotype