Eae1 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Eae1 (Experimental allergic encephalomyelitis QTL 1) Rattus norvegicus

Symbol: Eae1
Name: Experimental allergic encephalomyelitis QTL 1
RGD ID: 61474
Trait: nervous system integrity trait   (VT:0010566)    
Measurement Type: experimental autoimmune encephalomyelitis severity score   (CMO:0001419)    
LOD Score: 3.0
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2204,606,607 - 6,691,706RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0204,039,113 - 5,875,448RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0206,118,659 - 7,910,747RGDRnor5.0
RGSC_v3.4204,740,609 - 6,880,472RGDRGSC3.4
RGSC_v3.1204,740,837 - 6,880,698RGD
Cross Type: F2
Strains Crossed: DA E3 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
paresis  (QTM)
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
DA  (IEA)
E3  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Evidence for common autoimmune disease genes controlling onset, severity, and chronicity based on experimental models for multiple sclerosis and rheumatoid arthritis. Bergsteinsdottir K, etal., J Immunol 2000 Feb 1;164(3):1564-8
Related QTLs

Related QTL Description Reference
Pia1 maps to same region RGD:61031


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2209Wdr46WD repeat domain 462049378454945796Rat
2745Grm4glutamate metabotropic receptor 42054841725572821Rat
3618Vps52VPS52 subunit of GARP complex2049207154931685Rat
3370Ppardperoxisome proliferator-activated receptor delta2062987856363970Rat
2934Itpr3inositol 1,4,5-trisphosphate receptor, type 32051369685202339Rat
2373Col11a2collagen type XI alpha 2 chain2047869324816598Rat
3595Rps18ribosomal protein S182049314274935538Rat
3611Rxrbretinoid X receptor beta2048168134823267Rat
3817Tap1transporter 1, ATP binding cassette subfamily B member2046562624666634Rat
621024Rps10ribosomal protein S102056943135698922Rat
621227Daxxdeath-domain associated protein2049700904976145Rat
3819TapbpTAP binding protein2049569374966191Rat
2363Clpscolipase2066205296622709Rat
621090Syngap1synaptic Ras GTPase activating protein 12050263665056659Rat
3427Psmb9proteasome 20S subunit beta 92046670444672512Rat
620497Rpl10aribosomal protein L10A2063888006391358Rat
1303205Phf1PHD finger protein 12050177655022872Rat
628699Hmga1high mobility group AT-hook 12056110885618755Rat
1303158Hsd17b8hydroxysteroid (17-beta) dehydrogenase 82048267254828742Rat
3818Tap2transporter 2, ATP binding cassette subfamily B member2046363474650387Rat
1303050Zbtb9zinc finger and BTB domain containing 92050574335060459Rat
620328B3galt4Beta-1,3-galactosyltransferase 42049360894937664Rat
1303006Pfdn6prefoldin subunit 62049459594947433Rat
3426Psmb8proteasome 20S subunit beta 82046521594655122Rat
1303306CutacutA divalent cation tolerance homolog2050229565024580Rat
3247Pacsin1protein kinase C and casein kinase substrate in neurons 12057181345768064Rat
735096RT1-DMbRT1 class II, locus DMb2046931024700340Rat
3576Ring1ring finger protein 12048301204833623Rat
3477RT1-DOaRT1 class II, locus DOa2047535874756590Rat
1306008Armc12armadillo repeat containing 122065878596598355Rat
1306917Uqcc2ubiquinol-cytochrome c reductase complex assembly factor 22052028375214541Rat
1302985Ralgdsl2ral guanine nucleotide dissociation stimulator like 22049484954956774Rat
1304880Scube3signal peptide, CUB domain and EGF like domain containing 32061991826231100Rat
735053RT1-DMaRT1 class II, locus DMa2047070284710432Rat
1305341Lemd2LEM domain nuclear envelope protein 22052823975296621Rat
1305626Taf11TATA-box binding protein associated factor 112059557745963593Rat
1359370Lhfpl5LHFPL tetraspan subfamily member 52066323246642534Rat
1309155Fkbp5FKBP prolyl isomerase 52064572076575404Rat
1359387Tcp11t-complex 112061262676138408Rat
621635Bak1BCL2-antagonist/killer 12051004805109669Rat
1311583Tead3TEA domain transcription factor 32063920536411446Rat
1310183Nudt3nudix hydrolase 32056343455686950Rat
1308898Slc26a8solute carrier family 26 member 82066862066749478Rat
1306239Zfp523zinc finger protein 5232062348846266512Rat
1306065Snrpcsmall nuclear ribonucleoprotein polypeptide C2058884535906638Rat
1308272Srpk1SRSF protein kinase 12066458096682448Rat
1307945Def6DEF6 guanine nucleotide exchange factor2062685796290030Rat
1309183Anks1aankyrin repeat and sterile alpha motif domain containing 1A2059636586117139Rat
1307264Bltp3abridge-like lipid transfer protein family member 3A2059102615954641Rat
1303072AA926063AA926063gene2049764624988984Rat
1359627Zbtb22zinc finger and BTB domain containing 222049663314969853Rat
1359729Ggnbp1gametogenetin binding protein 12051098495116185Rat
1564450Smim29small integral membrane protein 292056188455620856Rat
1561045FanceFA complementation group E2063694166386631Rat
1359118Kifc1kinesin family member C12049988325017107Rat
1359610RT1-A3RT1 class I, locus A32048475184851344Rat
1311062Tulp1TUB like protein 12064121706424103Rat
1303324Brd2bromodomain containing 22047270784735389Rat
1559829Ilruninflammation and lipid regulator with UBA-like and NBR1-like domains2058099315876197Rat
1584104Ip6k3inositol hexakisphosphate kinase 32052238635245443Rat
1595921RT1-HaRT1 class II, locus Ha2047606314770662Rat
1595923RT1-A2RT1 class Ia, locus A22048709394910183Rat
1595924RT1-A1RT1 class Ia, locus A12049053094914593Rat
1594398Sacm2l-ps2Sacm2l-ps2 pseudogene2048602074861343Rat
1594399Sacm2l-ps1Sacm2l-ps1 pseudogene2048614394861499Rat
1594400LOC224733l-2LOC224733l-2 pseudogene2048669864867269Rat
1594401LOC224733l-1LOC224733l-1 pseudogene2048937044901482Rat
1594842SpdefSAM pointed domain containing ets transcription factor2057714405785893Rat
1593280Slc39a7solute carrier family 39 member 72048231664826538Rat
1592336Clpsl2colipase-like 22066081286610951Rat
1591984Cdk2ap1-ps1Cdk2ap1-pseudogene 12048778724878222Rat
1591985Sec61-psSec61 pseudogene2049909544991292Rat
1591986Rps25-ps1ribosomal protein S25, pseudogene 12049971124997779Rat
1595814RT1-DObRT1 class II, locus DOb2046194184625627Rat
1595866RT1-Hb-ps1RT1 class II, locus Hb, pseudogene 12047755984779590Rat
1642907Mlnmotilin2053042495308948Rat
2325545Mir219a1microRNA 219a-12048296874829796Rat
7662094LOC102552617uncharacterized LOC1025526172061361166142709Rat
7558298LOC102551791uncharacterized LOC1025517912053365675342262Rat
7574070LOC102551729uncharacterized LOC1025517292053270865330154Rat
11396817LOC108353257uncharacterized LOC1083532572052713225274062Rat
11481265LOC108349039uncharacterized LOC1083490392061717066177179Rat
11496771Smim40small integral membrane protein 402049786584989050Rat
41249976LOC120098971uncharacterized LOC1200989712066810606711596Rat
41359868Brd2lbromodomain containing 2 like2047150494726873Rat
41363335Trnaa-agc96transfer RNA alanine (anticodon AGC) 962049960874996159Rat
41213255LOC120098965uncharacterized LOC1200989652052967725304377Rat
41154967LOC120098963uncharacterized LOC1200989632051928055201154Rat
41370127LOC120098856uncharacterized LOC1200988562054243755429086Rat
41127036Trnap-agg65transfer RNA proline (anticodon AGG) 652063706596370739Rat
41106045LOC120099050U6 spliceosomal RNA2049281454928241Rat
41201546LOC120098818uncharacterized LOC1200988182053704375382107Rat
40927733LOC120098860uncharacterized LOC1200988602061608136170387Rat
40958994Trnaa-agc33transfer RNA alanine (anticodon AGC) 332065623546562428Rat
41315732LOC120098961uncharacterized LOC1200989612063593766367170Rat
41315246LOC120098897uncharacterized LOC1200988972048430814847572Rat
41016453LOC120098811uncharacterized LOC1200988112050991415106643Rat
41017433LOC120099029small nucleolar RNA SNORA262059164825916607Rat
41018858LOC120098906uncharacterized LOC1200989062053516275352349Rat
41239998LOC120098859uncharacterized LOC1200988592055870005602500Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
34280D20Mgh41062066915966691706Ratregion
37594D20Rat411952046066074606812Ratregion
38324D20Rat321602048391514839323Ratregion
41466D20Rat451252053045755304690Ratregion
43141D20Rat662022046754394675614Ratregion
66472D20Uia21692062321726232338Ratregion
1576369D20Ztm21592051064685106627Ratregion
1631989D20Wox131662065149776515143Ratregion
1626730D20Rhw111862046093814609567Ratregion
1626768D20Rhw131522052205125220664Ratregion
1626778D20Rhw101662046066464606812Ratregion
1628583D20Cebr12062822406282558Ratregion
1628583D20Cebr12062822406283195Ratregion
1638634D20Got1281792065911346591313Ratregion
1634943D20Cebr21232058029485803071Ratregion
1635374D20Got1192382064620366462274Ratregion
1637010D20Got1031442055879725588116Ratregion
2303209D20Yum761052047090294709134Ratregion
2303209D20Yum761052047090294709134Ratregion
2303227D20Yum781522047678524768004Ratregion
2303227D20Yum781522047678524768004Ratregion
2303243D20Yum821512049295044929655Ratregion
2303291D20Yum791582047956504795808Ratregion
2303297D20Yum751832046262034626386Ratregion
7206734MARC_5897-5898:997299407:12592048180114818559Ratregion
7206776RH6471111072050874405087471Ratregion
5036051Zfp2974542049672254967679Ratregion
5036334H2-D11562049085014908657Ratregion
5033919RH1406161842053299575330141Ratregion
7205922UniSTS:4634054202047875704788444Ratregion
5028753RH1421991832046667174666900Ratregion
5034566BE1196331622063277176327879Ratregion
5030027BI2798591062056098335609939Ratregion
5027517AW1257601512063921686392319Ratregion
5032973RH1371622322049207674921002Ratregion
5033451RH1388811272057651085765235Ratregion
5033661RH1396421882049372464937434Ratregion
5052057RH948151562063625286362684Ratregion
5051168RH1344781832063636816363864Ratregion
5057247AA9260632152049764974976712Ratregion
5057476AA8588701372057675305767669Ratregion
5054593RH1433131522062306466230798Ratregion
5058656BE1022691692051094135109582Ratregion
5056053RH1441561082062044756204583Ratregion
5059598BI2915202182065640996564317Ratregion
5058954BF3938581402048307114830851Ratregion
5058200BI2777091972049824174982614Ratregion
5059226BI2786881712059560095956180Ratregion
5057558BE0955671532057678735768026Ratregion
5057844BF3862482032052737815273984Ratregion
7193040Rxrb02048206574821131Ratregion
5051040RH1344032062061168416117047Ratregion
5053983RH1429631152056353235635438Ratregion
5050382RH1340241802051004935100673Ratregion
5051671Rxrb2882048188814820582Ratregion
5041670RH1289912102046722414672451Ratregion
5040910RH1285541802050601945060374Ratregion
5043532RH1300791942056188765619070Ratregion
5044600RH1306972172049665244966741Ratregion
5041560RH1289272042059543495954553Ratregion
5041594RH1289472052050226445022847Ratregion
5041598RH1289491802049786694978849Ratregion
5047544RH1323881832046931924693375Ratregion
5047544RH1323881832046931924693375Ratregion
5049182RH1333331942048284584828652Ratregion
5048212RH1327731532046522064653401Ratregion
5048212RH1327731532046522064653401Ratregion
5048462RH1329172152062662746266489Ratregion
5040032RH1280501942056184545618649Ratregion
5042648RH1295601892052020735202262Ratregion
5042660RH1295672122052019995202211Ratregion
5040482RH1283091832066476276647816Ratregion
5039930RH1279892142066460146646228Ratregion
5042260RH1293321872048263274826514Ratregion
5042402RH1294132052049569494957154Ratregion
5043582RH13010802049207224920922Ratregion
5040050RH1280611802064121766412356Ratregion
5040402RH1282631962062307986230993Ratregion
5072730RH1370201892066423026642491Ratregion
5072084RH1366422152048941464894361Ratregion
5074022RH1377741552049786924978847Ratregion
5072552RH1369152162047070454707261Ratregion
5072552RH1369152162047070454707261Ratregion
5076652RH1393001602052825785282738Ratregion
5074808RH1382301212054873255487446Ratregion
5077478RH1397791982061265586127390Ratregion
5077632RH1398681912046563654656556Ratregion
5076822RH1393982272046563174656544Ratregion
5075694RH1387421372049575204957657Ratregion
5077596RH1398472112060589326059143Ratregion
5078218RH1402122162056346275634843Ratregion
5079980RH1413132062049219834922189Ratregion
5078896RH1406141912049485254948716Ratregion
5078716RH1405092222049372124937434Ratregion
5066704AU0482001262046161384616264Ratregion
5070135RH94492952046723604672455Ratregion
5070211RH94536892047539554754044Ratregion
5070402AV0416581022065980016598103Ratregion
5060654BE1041851042049381004938204Ratregion
5062480BE1067281572049584824958639Ratregion
5063988BE1203831532066557036655856Ratregion
5062800AW5345051512051008355100986Ratregion
5064018BI2960251602052320725232232Ratregion
5065842AI0455032142066205746621167Ratregion
5062728AW5341061762052273405227516Ratregion
5064504BF411261962062395146239610Ratregion
5064726BE1084001762059054525905628Ratregion
5063170BE1138371692057714895771658Ratregion
5086913BM3868771742058901925890366Ratregion
5087785D17Dgm5752046701594670234Ratregion
5087914H2-Q63612049057184906260Ratregion
5082835BF3902031652049645194964684Ratregion
5087530PMC275467P44792052011935201672Ratregion
5083787AI5995271982051291445129342Ratregion
5088853AU0488091972046094154609612Ratregion
5084500AI2352232242048521044852328Ratregion
5084720AI0082581242050565025056626Ratregion
5080934RH1418682082049225914922798Ratregion
5086048AW5294181672060756186075785Ratregion
5086553BM3858171882048243484824536Ratregion
5085645BI2767031572063863916386548Ratregion
5085772BF4167341212056322905632411Ratregion
5084022AI2324781342049214324921566Ratregion
5503258UniSTS:2376241832049663694966552Ratregion
5503262UniSTS:2376262382048168724817110Ratregion
5503354CGCb741762047316994731873Ratregion
5503354CGCb741762047316994731873Ratregion
5503520H2-Ke610272048273294828356Ratregion
5503522UniSTS:46341511942050098835011077Ratregion
5503524Slc39a712342048251084826342Ratregion
5503528UniSTS:46343714872049247334926220Ratregion
5503827MARC_45796-45797:1102976080:113122063583066359618Ratregion
5503833MARC_45800-45801:1102973340:202063608796361416Ratregion
5505913UniSTS:49603314182063595076360925Ratregion
5506310Tap214532046374924638945Ratregion
5506310Tap214532046374924638945Ratregion
5500011UniSTS:2361251432050112135011477Ratregion
5501107PMC137182P91052063607786360883Ratregion
5502150MARC_6301-6302:997299518:102048177794818347Ratregion
Position Markers

Flank 1: (D20Rat41)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2204,606,607 - 4,606,812 (-)MAPPER
Rnor_6.0204,039,113 - 4,039,317NCBI
Rnor_5.0206,118,659 - 6,118,863UniSTS
RGSC_v3.4204,740,609 - 4,740,814RGD
RGSC_v3.4204,740,610 - 4,740,814UniSTS
RGSC_v3.1204,740,837 - 4,741,041RGD
Celera206,207,604 - 6,207,808UniSTS
RH 3.4 Map2067.2UniSTS
RH 3.4 Map2067.2RGD
RH 2.0 Map2074.2RGD
SHRSP x BN Map200.0RGD
FHH x ACI Map200.0RGD
Flank 2: (D20Mgh4)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2206,691,596 - 6,691,706 (+)MAPPER
Rnor_6.0205,875,339 - 5,875,448NCBI
Rnor_5.0207,910,638 - 7,910,747UniSTS
RGSC_v3.4206,880,363 - 6,880,472UniSTS
RGSC_v3.4206,880,362 - 6,880,471RGD
RGSC_v3.1206,880,589 - 6,880,698RGD
Celera208,247,548 - 8,247,657UniSTS
RH 3.4 Map2077.5UniSTS
RH 3.4 Map2077.5RGD
RH 2.0 Map2097.1RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20460660717617956Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20669170617489458Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7175096Tcs1T cell selection QTL 1T cell selectionexpression2047270785024580Rat
7175099Tcs2T cell selection QTL 2T cell selectionexpression2045040024693102Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
61474Eae1Experimental allergic encephalomyelitis QTL 13nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)2046066076691706Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20460660717617956Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362164910078919Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036216499243559Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
737973Pia21Pristane induced arthritis QTL 214.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2036216564606812Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Eae1

RGD Curation Notes
Note Type Note Reference