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General

QTL: Bp16 (Blood pressure QTL 16) Rattus norvegicus

Symbol:

Bp16

Name:

Blood pressure QTL 16

RGD ID:

61469

Trait:

arterial blood pressure trait (VT:2000000)

Measurement Type:

blood pressure measurement (CMO:0000003)

LOD Score:

5.64

P Value:

Not Available

Variance:

Not Available

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	169,745,596 - 214,745,596	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	2	184,730,446 - 229,730,446	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	2	204,149,709 - 249,149,709	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	2	177,484,675 - 222,484,675	RGD_MAPPER_PIPELINE	RGSC3.4
RGSC_v3.1	2	177,447,430 - 222,447,430	RGD

Cross Type:

Strains Crossed:

SHR WKY

Annotation Click to see Annotation Detail View

Candidate Gene Status

Atp1a1 is a candidate Gene for Bp16

Disease Annotations Click to see Annotation Detail View

hypertension (IDA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

increased systemic arterial blood pressure (QTM)

Experimental Data Annotations Click to see Annotation Detail View

Clinical Measurement

blood pressure measurement (IDA)

Experimental Condition

control condition (IDA)

Measurement Method

tail cuff plethysmography (IDA)

Vertebrate Trait

arterial blood pressure trait (IDA)

Rat Strain

SHR (IEA)

WKY (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Chromosome 2 reciprocal congenic strains to evaluate the effect of the genetic background on blood pressure.	Carr FJ, etal., Scott Med J 2002 Feb;47(1):7-9.
2.	Detection and positional cloning of blood pressure quantitative trait loci: is it possible? Identifying the genes for genetic hypertension.	Rapp JP and Deng AY, Hypertension 1995 Jun;25(6):1121-8.
3.	Analysis of quantitative trait loci for blood pressure on rat chromosomes 2 and 13. Age-related differences in effect.	Samani NJ, etal., Hypertension 1996 Dec;28(6):1118-22
4.	A biometrical genome search in rats reveals the multigenic basis of blood pressure variation.	Schork NJ, etal., Genome Res 1995 Sep;5(2):164-72

Related QTLs

Related QTL	Description	Reference
Bp19	interacts with	RGD:61045
Bp10	maps to same region	RGD:619639
Bp14	interacts with	RGD:728179

Region

Markers in Region

The following Markers overlap with this region.

RGD ID

Symbol

Expected Size

Chr

Start

Stop

Species

Match

Position Markers

Peak: (D2Wox7)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	192,245,536 - 192,245,657 (+)	MAPPER
Rnor_6.0	2	207,230,387 - 207,230,505	NCBI
Rnor_5.0	2	226,649,650 - 226,649,768	UniSTS
RGSC_v3.4	2	199,984,617 - 199,984,735	UniSTS
RGSC_v3.4	2	199,984,616 - 199,984,735	RGD
Celera	2	184,712,392 - 184,712,510	UniSTS
RGSC_v3.1	2	199,947,371 - 199,947,489	RGD
RH 3.4 Map	2	1346.5	UniSTS
RH 3.4 Map	2	1346.5	RGD

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	Bp16

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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QTL: Bp16 (Blood pressure QTL 16) Rattus norvegicus

Mammalian Phenotype