Pur1 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Pur1 (Proteinuria QTL 1) Rattus norvegicus

Symbol: Pur1
Name: Proteinuria QTL 1
RGD ID: 61453
Trait: urine total protein amount   (VT:0000032)    
Measurement Type: urine protein level   (CMO:0000591)    
LOD Score: 18.06
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21334,535,218 - 37,415,726RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01339,372,927 - 42,310,885RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01344,494,434 - 47,416,214RGDRnor5.0
RGSC_v3.41335,472,372 - 38,489,943RGDRGSC3.4
RGSC_v3.1130 - 38,503,986RGD
Cross Type: (BUF/Mna x WKY/NCrj) x BUF/Mna backcross
Strains Crossed: BUF/Mna WKY/NCrlCrlj 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
proteinuria  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Vertebrate Trait

Rat Strain
BUF/Mna  (IEA)
WKY/NCrlCrlj  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Actin -related protein 3 (Arp3) is mutated in proteinuric BUF/Mna rats. Akiyama K, et al., Mamm Genome. 2008 Jan;19(1):41-50. Epub 2007 Dec 7.
2. A genetic locus susceptible to the overt proteinuria in BUF/Mna rat. Murayama S, etal., Mamm Genome 1998 Nov;9(11):886-8.
Related QTLs

Related QTL Description Reference
Pur16 sub_region RGD:2292230


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1306427Dpp10dipeptidyl peptidase like 10133458442036269292Rat
41154132LOC120096396small nucleolar RNA SNORA17133466251334662643Rat
41054534LOC120096424U2 spliceosomal RNA133485878534858948Rat
41334534Rpl23a-ps18ribosomal protein L23a, pseudogene 18133557156735572037Rat
11432035LOC108352624uncharacterized LOC108352624133594992936144808Rat
41288161LOC120096236uncharacterized LOC120096236133641760236440116Rat
7713048LOC102554127uncharacterized LOC102554127133646666736468943Rat
71024Actr3actin related protein 3133680073936843837Rat
7577736LOC102554198uncharacterized LOC102554198133684413936862825Rat
41047751LOC120096237uncharacterized LOC120096237133686292036867620Rat
1308125Slc35f5solute carrier family 35, member F5133699211837028549Rat
1306745Gpr39G protein-coupled receptor 39133711525837327312Rat
1549754Lypd1Ly6/Plaur domain containing 1133732645937368515Rat
1564507Nckap5NCK-associated protein 5133736994838283257Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
34351D13Mgh4150133741558437415726Ratregion
34371D13Mgh3142133453521834535351Ratregion
36747D13Rat20138133726209237262232Ratregion
38530D13Rat94216133626080636261020Ratregion
41222D13Rat114145133735094937351078Ratregion
41338D13Rat115138133477861934778759Ratregion
42989D13Rat199149133663126636631415Ratregion
42990D13Rat148149133534432535344477Ratregion
40776D13Rat117212133653047236530684Ratregion
45024D13Got109127133463477934634906Ratregion
45025D13Got8111133615572336155834Ratregion
45026D13Got6180133738636237386542Ratregion
45035D13Got1219133613919136139409Ratregion
45036D13Got3290133643083936431129Ratregion
45037D13Got5252133647052336470772Ratregion
45039D13Got4169133714003737140206Ratregion
45040D13Got7149133689930736899456Ratregion
1581962D13Hmgc86325133540799035408317Ratregion
1582020D13Hmgc89207133636039436360601Ratregion
1633101D13Got236183133539109835391279Ratregion
1637510D13Got260255133492690834927163Ratregion
2324937D13Hmgc93173133740646737406640Ratregion
7191227D13MGH3142133453521734535351Ratregion
5032052AU046910135133699109036991227Ratregion
5032335AI853408118133732675837326876Ratregion
5033201RH137955147133732807337328220Ratregion
5030645BI301555173133685319036853363Ratregion
5056019RH144136105133563776035637865Ratregion
5056745RH144555170133459433134594501Ratregion
5047192RH132186182133541483235415014Ratregion
5066596AU048264136133738366937383805Ratregion
5066722AU048189170133672664736726812Ratregion
5066890AU048090215133559552735595742Ratregion
5067520AU047695164133540039235400556Ratregion
5068446AU047140128133741422137414349Ratregion
5068884AU046866236133726317937263410Ratregion
5088515AU048615186133539799535398176Ratregion
5089595AU049248172133461219734612367Ratregion
5081683BF41457692133731880737318899Ratregion
5088425AU048561138133645167436451812Ratregion
5088425AU048561138133645170436451812Ratregion
5089095AU048951141133667175336671894Ratregion
5506795G45485299133707800937078308Ratregion
Position Markers

Flank 1: (D13Mgh3)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21334,535,218 - 34,535,351 (+)MAPPER
Rnor_6.01339,372,927 - 39,373,058NCBI
Rnor_5.01344,494,434 - 44,494,565UniSTS
RGSC_v3.41335,472,372 - 35,472,503UniSTS
Celera1334,363,454 - 34,363,585UniSTS
RH 3.4 Map130.0RGD
RH 3.4 Map130.0UniSTS
RH 2.0 Map13168.5RGD
Cytogenetic Map13 RGD
Flank 2: (D13Mgh4)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21337,415,584 - 37,415,726 (+)MAPPER
Rnor_6.01342,310,744 - 42,310,885NCBI
Rnor_5.01347,416,073 - 47,416,214UniSTS
RGSC_v3.41338,489,801 - 38,489,943RGD
RGSC_v3.41338,489,802 - 38,489,943UniSTS
RGSC_v3.11338,503,844 - 38,503,986RGD
Celera1337,210,510 - 37,210,651UniSTS
RH 2.0 Map13248.6RGD
SHRSP x BN Map137.9399RGD
FHH x ACI Map139.21RGD
Cytogenetic Map13q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13142356786Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
631672Iddm12Insulin dependent diabetes mellitus QTL 122.20.0032blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)13599466834535351Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13599466844807491Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)13931346554313465Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131192944945417941Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131192944946193066Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131515872260158722Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131769443653050594Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132369296968692969Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132369296968692969Rat
2303030Bp327Blood pressure QTL 327arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133039535141184251Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133124133158363171Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
61453Pur1Proteinuria QTL 118.06urine total protein amount (VT:0000032)urine protein level (CMO:0000591)133453521837415726Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
2292232Pur16Proteinuria QTL 1617.2urine total protein amount (VT:0000032)urine protein level (CMO:0000591)133615572341961389Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Pur1

RGD Curation Notes
Note Type Note Reference
qtl_cross_type (BUF/Mna x WKY/NCrj) x BUF/Mna backcross