GWAS1676409_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1676409_H (paralytic strabismus QTL GWAS1676409 (human)) Homo sapiens

Symbol: GWAS1676409_H
Name: paralytic strabismus QTL GWAS1676409 (human)
RGD ID: 597619549
Trait: paralytic strabismus
LOD Score: Not Available
P Value: 2.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38611,377,969 - 11,377,970RGD_MAPPER_PIPELINEGRCh38
GRCh37611,378,202 - 11,378,203RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1314803NEDD9neural precursor cell expressed, developmentally down-regulated 961118329811382348Human

Position Markers

Peak: (rs181930706)
Human AssemblyChrPosition (strand)Source
GRCh38611,377,969 - 11,377,970RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289408BW324_HBody weight QTL 324 (human)3.150.0001Body fat amount6120803913Human
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
597619549GWAS1676409_Hparalytic strabismus QTL GWAS1676409 (human)2e-12paralytic strabismus61137796911377970Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
2289435BMD4_HBone mineral density QTL 4 (human)3.150.0001Bone mineral density6120803913Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
2292824PRSTS5_HProstate tumor susceptibility QTL 5 (human)Prostate tumor susceptibility6119232373Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human
1643495BW291_HBody Weight QTL 291 (human)2.13Body weightBMI6119321359Human
1643399BMD5_HBone mineral density QTL 5 (human)2.320.0005Bone mineral density6691196032911960Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1676409_H GCST90480097 Paralytic strabismus (PheCode 378.5) 506 African American or Afro-Caribbean cases, 121,121 African American or Afro-Caribbean controls, 2,392 European ancestry cases, 447,453 European ancestry controls, 443 Hispanic or Latin American cases, 59,298 Hispanic or Latin American controls G 0.9992 2E-12 11.699 rs181930706 2.131 paralytic strabismus (EFO:0009678)
 PMID:39024449
Database Acc Id Source(s)
GWAS Catalog GCST90480097 GWAS Catalog

RGD Curation Notes
Note Type Note Reference