GWAS1671957_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1671957_H (hydronephrosis QTL GWAS1671957 (human)) Homo sapiens

Symbol: GWAS1671957_H
Name: hydronephrosis QTL GWAS1671957 (human)
RGD ID: 597615097
Trait: hydronephrosis
LOD Score: Not Available
P Value: 2.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381620,348,311 - 20,348,312RGD_MAPPER_PIPELINEGRCh38
GRCh371620,359,633 - 20,359,634RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1671957_HHumanhydronephrosis  IAGPrs28544423405850206 GWAS_CATALOGPMID:39024449
Disease Annotations     Click to see Annotation Detail View
hydronephrosis  (IAGP)

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
737075UMODuromodulin162033305120356301Human

Position Markers

Peak: (rs28544423)
Human AssemblyChrPosition (strand)Source
GRCh381620,348,311 - 20,348,312RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597615097GWAS1671957_Hhydronephrosis QTL GWAS1671957 (human)2e-11hydronephrosis162034831120348312Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1820799_H GCST90565167 Kidney stone disease 4,812 European ancestry individuals, 585 Black individuals, 174 cases, 83,692 controls T 0.16 3E-9 8.523 rs28544423 1.17 nephrolithiasis (EFO:0004253)
 PMID:39156495
GWAS1671957_H GCST90480399 Hydronephrosis (PheCode 595) 1,548 African American or Afro-Caribbean cases, 118,995 African American or Afro-Caribbean controls, 7,337 European ancestry cases, 436,719 European ancestry controls, 742 Hispanic or Latin American cases, 58,297 Hispanic or Latin American controls C 0.8432 2E-11 10.699 rs28544423 0.1339 hydronephrosis (EFO:0005562)
 PMID:39024449
Database Acc Id Source(s)
GWAS Catalog GCST90480399 GWAS Catalog

RGD Curation Notes
Note Type Note Reference