GWAS1594053_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1594053_H (lean body mass QTL GWAS1594053 (human)) Homo sapiens

Symbol: GWAS1594053_H
Name: lean body mass QTL GWAS1594053 (human)
RGD ID: 597497979
Trait: body lean mass   (VT:0010483)    
Measurement Type: total body lean mass   (CMO:0003950)    
LOD Score: Not Available
P Value: 1.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381589,384,958 - 89,384,959RGD_MAPPER_PIPELINEGRCh38
GRCh371589,928,189 - 89,928,190RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1594053_HHumantotal body lean mass  IAGPrs150353405850206 GWAS_CATALOGPMID:38538606

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1594053_HHumanbody lean mass  IAGPrs150353405850206 GWAS_CATALOGPMID:38538606

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1594053_HHumanlean body mass  IAGPrs150353405850206 GWAS_CATALOGPMID:38538606
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait
body lean mass  (IAGP)

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
7244794MIR9-3HGMIR9-3 host gene158936157989398488Human

Position Markers

Peak: (rs150353)
Human AssemblyChrPosition (strand)Source
GRCh381589,384,958 - 89,384,959RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597515384GWAS1611458_Hbody mass index QTL GWAS1611458 (human)9e-13body mass indexbody mass index (BMI) (CMO:0000105)158938495889384959Human
597497979GWAS1594053_Hlean body mass QTL GWAS1594053 (human)1e-11body lean mass (VT:0010483)total body lean mass (CMO:0003950)158938495889384959Human
597399340GWAS1495414_Hschizophrenia QTL GWAS1495414 (human)0.0000001schizophrenia158938495889384959Human
597464756GWAS1560830_Htobacco smoke exposure measurement QTL GWAS1560830 (human)3e-08tobacco smoke exposure measurement158938495889384959Human
597408245GWAS1504319_Hbody mass index QTL GWAS1504319 (human)6e-10body mass indexbody mass index (BMI) (CMO:0000105)158938495889384959Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1495414_H GCST90128471 Schizophrenia 53,386 European ancestry cases, 77,258 European ancestry controls, 14,004 East Asian ancestry cases, 16,757 East Asian ancestry controls, 6,152 African American cases, 3,918 African American controls, 1,234 Latino cases, 3,090 Latino controls T 0.574 1E-7 7 rs150353 0.96156 PMID:35396580
GWAS1504319_H GCST90018947 Body mass index 359,983 European ancestry individuals, 163,835 East Asian ancestry individuals G NR 6E-10 9.222 rs150353 0.0117 body mass index (EFO:0004340)
 PMID:34594039
GWAS1560830_H GCST008803 Smoking behaviour (cigarette pack-years) up to 150,993 European ancestry individuals G 0.448 3E-8 7.523 rs150353 0.0205 tobacco smoke exposure measurement (EFO:0009115)
 PMID:30679032
GWAS1594053_H GCST90428120 Whole body fat free mass (UKB data field 23101) 337,739 European ancestry individuals G NR 1E-11 11 rs150353 0.00898635 lean body mass (EFO:0004995)
 PMID:38538606
GWAS1611458_H GCST90255621 Body mass index 1,122,049 European ancestry individuals G NR 9E-13 12.046 rs150353 0.011 body mass index (EFO:0004340)
 PMID:36581621
Database Acc Id Source(s)
GWAS Catalog GCST90428120 GWAS Catalog

RGD Curation Notes
Note Type Note Reference