GWAS1126851_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL: GWAS1126851_H (tobacco smoke exposure measurement QTL GWAS1126851 (human)) Homo sapiens

Symbol: GWAS1126851_H
Name: tobacco smoke exposure measurement QTL GWAS1126851 (human)
RGD ID: 597030777
Trait: tobacco smoke exposure measurement
LOD Score: Not Available
P Value: 2.0E-16
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382063,360,481 - 63,360,482RGD_MAPPER_PIPELINEGRCh38
GRCh372061,991,833 - 61,991,834RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1126851_HHumantobacco smoke exposure measurement  IAGPrs45497800405850206 GWAS_CATALOGPMID:30679032
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
10356CHRNA4cholinergic receptor nicotinic alpha 4 subunit206334322363361349Human
16551535AL121827.1novel transcript, antisense to CHRNA4206335998863371177Human

Position Markers

Peak: (rs45497800)
Human AssemblyChrPosition (strand)Source
GRCh382063,360,481 - 63,360,482RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597187128GWAS1283202_Hsmoking cessation QTL GWAS1283202 (human)7e-41smoking cessation206336048163360482Human
2292864PRSTS43_HProstate tumor susceptibility QTL 43 (human)0.620.05Prostate tumor susceptibility204730303964444167Human
597030777GWAS1126851_Htobacco smoke exposure measurement QTL GWAS1126851 (human)2e-16tobacco smoke exposure measurement206336048163360482Human
597333287GWAS1429361_Hsmoking cessation QTL GWAS1429361 (human)1e-38smoking cessation206336048163360482Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1126851_H GCST008803 Smoking behaviour (cigarette pack-years) up to 150,993 European ancestry individuals T 0.0867 2E-16 15.699 rs45497800 0.0541 tobacco smoke exposure measurement (EFO:0009115)
PMID:30679032
GWAS1283202_H GCST90243988 Smoking cessation 1,400,535 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals T 0.0811 7E-41 40.155 rs45497800 0.0309 smoking cessation (EFO:0004319)
PMID:36477530
GWAS1429361_H GCST90243980 Smoking cessation 1,147,272 European ancestry individuals T 0.0843 1E-38 38 rs45497800 0.031 smoking cessation (EFO:0004319)
PMID:36477530
Database Acc Id Source(s)
GWAS Catalog GCST008803 GWAS Catalog

RGD Curation Notes
Note Type Note Reference