GWAS1126850_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

QTL: GWAS1126850_H (tobacco smoke exposure measurement QTL GWAS1126850 (human)) Homo sapiens

Symbol: GWAS1126850_H
Name: tobacco smoke exposure measurement QTL GWAS1126850 (human)
RGD ID: 597030776
Trait: tobacco smoke exposure measurement
LOD Score: Not Available
P Value: 6.0E-25
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381940,847,202 - 40,847,203RGD_MAPPER_PIPELINEGRCh38
GRCh371941,353,107 - 41,353,108RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1126850_HHumantobacco smoke exposure measurement  IAGPrs56113850405850206 GWAS_CATALOGPMID:30679032
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1343424CYP2A6cytochrome P450 family 2 subfamily A member 6194084354140850447Human

Position Markers

Peak: (rs56113850)
Human AssemblyChrPosition (strand)Source
GRCh381940,847,202 - 40,847,203RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597267354GWAS1363428_Hlow density lipoprotein cholesterol measurement QTL GWAS1363428 (human)3e-17low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)194084720240847203Human
597188511GWAS1284585_Htheobromine measurement QTL GWAS1284585 (human)1e-11theobromine measurement194084720240847203Human
597231507GWAS1327581_Hcigarettes per day measurement QTL GWAS1327581 (human)5e-58cigarettes per day measurement194084720240847203Human
597596821GWAS1653681_Hglomerular filtration rate QTL GWAS1653681 (human)3e-17glomerular filtration rateblood low density lipoprotein cholesterol level (CMO:0000053)194084720240847203Human
597259669GWAS1355743_Hvery low density lipoprotein cholesterol measurement QTL GWAS1355743 (human)7e-09very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)194084720240847203Human
407159369GWAS808345_Hemphysema pattern measurement QTL GWAS808345 (human)1e-09taste liking measurement194084720240847203Human
597332629GWAS1428703_Hcigarettes per day measurement QTL GWAS1428703 (human)6e-207cigarettes per day measurement194084720240847203Human
597591179GWAS1648039_Hrespiratory system cancer QTL GWAS1648039 (human)1e-24respiratory system cancer194084720240847203Human
597187213GWAS1283287_HX-21286 measurement QTL GWAS1283287 (human)2e-19paraxanthine measurement194084720240847203Human
597034380GWAS1130454_Hlow density lipoprotein cholesterol measurement QTL GWAS1130454 (human)2e-10chronotype measurementblood low density lipoprotein cholesterol level (CMO:0000053)194084720240847203Human
597279619GWAS1375693_H3-methylxanthine measurement QTL GWAS1375693 (human)9e-183-methylxanthine measurement194084720240847203Human
597122443GWAS1218517_Hlung cancer QTL GWAS1218517 (human)1e-43lung cancer194084720240847203Human
597254020GWAS1350094_Hserum alanine aminotransferase measurement QTL GWAS1350094 (human)1e-15serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)194084720240847203Human
597321093GWAS1417167_HX-12216 measurement QTL GWAS1417167 (human)7e-35X-12216 measurement194084720240847203Human
597587390GWAS1644250_Hasphyxia, hypoxemia QTL GWAS1644250 (human)5e-13asphyxia, hypoxemia194084720240847203Human
597586879GWAS1643739_Hcreatinine measurement QTL GWAS1643739 (human)2e-12creatinine measurementblood creatinine measurement (CMO:0000767)194084720240847203Human
597188285GWAS1284359_HX-12216 measurement QTL GWAS1284359 (human)7e-18X-12216 measurement194084720240847203Human
597114047GWAS1210121_Hbitter beverage consumption measurement QTL GWAS1210121 (human)8e-11X-18935 measurementdrink intake measurement (CMO:0000771)194084720240847203Human
597321907GWAS1417981_H1,7-dimethylurate measurement QTL GWAS1417981 (human)3e-241,7-dimethylurate measurement194084720240847203Human
597048765GWAS1144839_Hnon-small cell lung carcinoma QTL GWAS1144839 (human)3e-09non-small cell lung carcinoma194084720240847203Human
597595825GWAS1652685_Hcreatinine measurement QTL GWAS1652685 (human)5e-17creatinine measurementblood creatinine measurement (CMO:0000767)194084720240847203Human
597590961GWAS1647821_Hasphyxia, hypoxemia QTL GWAS1647821 (human)3e-14asphyxia, hypoxemia194084720240847203Human
597176247GWAS1272321_Hcigarettes per day measurement QTL GWAS1272321 (human)3e-214cigarettes per day measurement194084720240847203Human
597614510GWAS1671370_Hsmoking behaviour measurement QTL GWAS1671370 (human)1e-26paraxanthine measurement194084720240847203Human
597316523GWAS1412597_HX-21286 measurement QTL GWAS1412597 (human)7e-38X-21286 measurement194084720240847203Human
597323944GWAS1420018_Hparaxanthine measurement QTL GWAS1420018 (human)1e-26paraxanthine measurement194084720240847203Human
597614507GWAS1671367_Hsmoking status measurement QTL GWAS1671367 (human)7e-15indolin-2-one measurement194084720240847203Human
597319087GWAS1415161_Hindolin-2-one measurement QTL GWAS1415161 (human)1e-30indolin-2-one measurement194084720240847203Human
597167278GWAS1263352_Halkaline phosphatase measurement QTL GWAS1263352 (human)1e-89alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)194084720240847203Human
407121273GWAS770249_Hforced expiratory volume, response to bronchodilator QTL GWAS770249 (human)2e-08free cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)194084720240847203Human
597607645GWAS1664505_Hsmoking behaviour measurement QTL GWAS1664505 (human)1e-27smoking behaviour measurement194084720240847203Human
597171419GWAS1267493_Hcigarettes per day measurement QTL GWAS1267493 (human)2e-78cigarettes per day measurement194084720240847203Human
597189083GWAS1285157_H6-hydroxyindole sulfate measurement QTL GWAS1285157 (human)6e-136-hydroxyindole sulfate measurement194084720240847203Human
597607642GWAS1664502_Hsmoking status measurement QTL GWAS1664502 (human)6e-19smoking status measurement194084720240847203Human
597162448GWAS1258522_Hlinoleic acid measurement QTL GWAS1258522 (human)6e-09linoleic acid measurementblood free fatty acids level (CMO:0000117)194084720240847203Human
1559110SCL22_HSerum cholesterol level QTL 22 (human)3.590.000241Lipid levelLDL cholesterol193190759457907594Human
597152705GWAS1248779_Hlow density lipoprotein cholesterol measurement QTL GWAS1248779 (human)1e-08very low density lipoprotein cholesterol measurement, phospholipid measurementblood very low density lipoprotein cholesterol level (CMO:0000648)194084720240847203Human
597141704GWAS1237778_HX-12216 measurement QTL GWAS1237778 (human)4e-20X-12216 measurement194084720240847203Human
407120678GWAS769654_HFEV/FVC ratio, response to bronchodilator QTL GWAS769654 (human)5e-09FEV/FVC ratio, response to bronchodilatorforced expiratory volume to forced vital capacity ratio (CMO:0000241)194084720240847203Human
597333752GWAS1429826_Hsmoking cessation QTL GWAS1429826 (human)5e-114smoking cessation194084720240847203Human
597259258GWAS1355332_Hlow density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS1355332 (human)4e-09low density lipoprotein cholesterol measurement, phospholipid measurementblood low density lipoprotein cholesterol level (CMO:0000053)194084720240847203Human
407089959GWAS738935_Hapolipoprotein B measurement QTL GWAS738935 (human)6e-11apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)194084720240847203Human
597123315GWAS1219389_Hsquamous cell lung carcinoma QTL GWAS1219389 (human)6e-21squamous cell lung carcinoma194084720240847203Human
406900517GWAS549493_Hcaffeine metabolite measurement QTL GWAS549493 (human)9e-22caffeine metabolite measurement194084720240847203Human
597267967GWAS1364041_Hsquamous cell lung carcinoma QTL GWAS1364041 (human)3e-11squamous cell lung carcinoma194084720240847203Human
597159921GWAS1255995_Hglycine measurement QTL GWAS1255995 (human)3e-08apolipoprotein A 1 measurement, apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)194084720240847203Human
406900520GWAS549496_Hcaffeine metabolite measurement QTL GWAS549496 (human)6e-08caffeine metabolite measurement194084720240847203Human
406900521GWAS549497_Hcaffeine metabolite measurement QTL GWAS549497 (human)0.000004caffeine metabolite measurement194084720240847203Human
597136381GWAS1232455_H3-methylxanthine measurement QTL GWAS1232455 (human)2e-24indolin-2-one measurement194084720240847203Human
597312246GWAS1408320_HX-21831 measurement QTL GWAS1408320 (human)8e-31X-21831 measurement194084720240847203Human
597313014GWAS1409088_HX-12126 measurement QTL GWAS1409088 (human)3e-14X-12126 measurement194084720240847203Human
597281015GWAS1377089_HX-12216 measurement QTL GWAS1377089 (human)3e-15X-12216 measurement194084720240847203Human
597247976GWAS1344050_Hnicotine metabolite ratio QTL GWAS1344050 (human)1e-37response to nicotine trait (VT:0010721)194084720240847203Human
596958688GWAS1078207_Hcoffee consumption measurement QTL GWAS1078207 (human)5e-19coffee consumption measurement194084720240847203Human
597159650GWAS1255724_Hapolipoprotein B measurement QTL GWAS1255724 (human)9e-09apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)194084720240847203Human
597590502GWAS1647362_Hinvasive mechanical ventilation QTL GWAS1647362 (human)1e-11invasive mechanical ventilation194084720240847203Human
597258720GWAS1354794_Hvery low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS1354794 (human)4e-08very low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)194084720240847203Human
597043944GWAS1140018_Hsmoking cessation QTL GWAS1140018 (human)7e-33smoking cessation194084720240847203Human
597247975GWAS1344049_Hnicotine metabolite ratio QTL GWAS1344049 (human)7e-22response to nicotine trait (VT:0010721)194084720240847203Human
597318372GWAS1414446_HX-12126 measurement QTL GWAS1414446 (human)6e-26X-12126 measurement194084720240847203Human
597278492GWAS1374566_H6-hydroxyindole sulfate measurement QTL GWAS1374566 (human)2e-116-hydroxyindole sulfate measurement194084720240847203Human
597587224GWAS1644084_Hbronchus cancer QTL GWAS1644084 (human)3e-21bronchus cancer194084720240847203Human
597140253GWAS1236327_HX-21286 measurement QTL GWAS1236327 (human)8e-12X-12216 measurement194084720240847203Human
597278487GWAS1374561_Hindolin-2-one measurement QTL GWAS1374561 (human)7e-15indolin-2-one measurement194084720240847203Human
407266516GWAS915492_Hcoffee consumption measurement, tea consumption measurement QTL GWAS915492 (human)2e-29coffee consumption measurement, tea consumption measurementdrink intake measurement (CMO:0000771)194084720240847203Human
597275146GWAS1371220_Hcoffee consumption measurement QTL GWAS1371220 (human)8e-19coffee consumption measurement194084720240847203Human
597587213GWAS1644073_Hrespiratory system cancer QTL GWAS1644073 (human)7e-21respiratory system cancer194084720240847203Human
597323522GWAS1419596_H3-methylxanthine measurement QTL GWAS1419596 (human)3e-443-methylxanthine measurement194084720240847203Human
597321472GWAS1417546_Htheobromine measurement QTL GWAS1417546 (human)8e-20theobromine measurement194084720240847203Human
597208067GWAS1304141_Hresponse to aromatase inhibitor QTL GWAS1304141 (human)2e-13response to aromatase inhibitorblood non-high density lipoprotein cholesterol level (CMO:0003967)194084720240847203Human
597218106GWAS1314180_Hnicotine dependence QTL GWAS1314180 (human)4e-16nicotine dependence194084720240847203Human
597226557GWAS1322631_Hcigarettes per day measurement QTL GWAS1322631 (human)4e-99cigarettes per day measurement194084720240847203Human
597323327GWAS1419401_Hnon-high density lipoprotein cholesterol measurement QTL GWAS1419401 (human)2e-14non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)194084720240847203Human
597595704GWAS1652564_Hchloride measurement QTL GWAS1652564 (human)4e-11chloride measurementblood chloride level (CMO:0000497)194084720240847203Human
597048638GWAS1144712_Hlung adenocarcinoma QTL GWAS1144712 (human)0.000008lung adenocarcinoma194084720240847203Human
597122623GWAS1218697_Hlung adenocarcinoma QTL GWAS1218697 (human)3e-21lung adenocarcinoma194084720240847203Human
597061951GWAS1158025_Hsquamous cell lung carcinoma QTL GWAS1158025 (human)7e-11upper aerodigestive tract neoplasmdrink intake measurement (CMO:0000771)194084720240847203Human
597043772GWAS1139846_Hcotinine measurement, cigarettes per day measurement QTL GWAS1139846 (human)3e-13cotinine measurement, cigarettes per day measurement194084720240847203Human
597187123GWAS1283197_Hsmoking cessation QTL GWAS1283197 (human)1e-120smoking cessation194084720240847203Human
597595954GWAS1652814_Hglomerular filtration rate QTL GWAS1652814 (human)2e-18glomerular filtration rateglomerular filtration rate (CMO:0000490)194084720240847203Human
597587759GWAS1644619_Hglomerular filtration rate QTL GWAS1644619 (human)5e-12glomerular filtration rateglomerular filtration rate (CMO:0000490)194084720240847203Human
597183785GWAS1279859_Hparaxanthine measurement QTL GWAS1279859 (human)3e-12theobromine measurementserum alanine aminotransferase activity level (CMO:0000575)194084720240847203Human
597043753GWAS1139827_Hnicotine metabolite ratio QTL GWAS1139827 (human)6e-261response to nicotine trait (VT:0010721)194084720240847203Human
597179730GWAS1275804_Hglycine measurement QTL GWAS1275804 (human)7e-10glycine measurementblood amino acid measurement (CMO:0003730)194084720240847203Human
597596243GWAS1653103_Hcreatinine measurement QTL GWAS1653103 (human)2e-20creatinine measurementblood creatinine measurement (CMO:0000767)194084720240847203Human
597269577GWAS1365651_Hlung carcinoma QTL GWAS1365651 (human)8e-27lung carcinoma194084720240847203Human
597069383GWAS1165457_Hlung carcinoma QTL GWAS1165457 (human)4e-13lung carcinoma194084720240847203Human
597307465GWAS1403539_Hglomerular filtration rate QTL GWAS1403539 (human)9e-13glomerular filtration rateglomerular filtration rate (CMO:0000490)194084720240847203Human
597226572GWAS1322646_Hsmoking cessation QTL GWAS1322646 (human)2e-48smoking cessation194084720240847203Human
407085204GWAS734180_Hnon-small cell lung carcinoma QTL GWAS734180 (human)3e-09non-small cell lung carcinoma194084720240847203Human
597030722GWAS1126796_Hcigarettes per day measurement QTL GWAS1126796 (human)3e-68cigarettes per day measurement194084720240847203Human
597608009GWAS1664869_Hsmoking behaviour measurement QTL GWAS1664869 (human)2e-16low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)194084720240847203Human
407121820GWAS770796_Hnicotine metabolite ratio QTL GWAS770796 (human)1e-50response to nicotine trait (VT:0010721)194084720240847203Human
597329730GWAS1425804_Hhydroxycotinine measurement QTL GWAS1425804 (human)2e-12hydroxycotinine measurement194084720240847203Human
597313094GWAS1409168_HX-18935 measurement QTL GWAS1409168 (human)1e-29X-18935 measurement194084720240847203Human
1331657COPD9_HChronic obstructive pulmonary disease QTL 9 (human)1.94Chronic airflow obstructionpost-bronchodilator FEV1193102176057021760Human
597225541GWAS1321615_Hsmoking cessation QTL GWAS1321615 (human)6e-10smoking cessation194084720240847203Human
597114441GWAS1210515_Hcoffee consumption measurement QTL GWAS1210515 (human)8e-16C-reactive protein measurementblood C-reactive protein level (CMO:0003160)194084720240847203Human
597141108GWAS1237182_H6-hydroxyindole sulfate measurement QTL GWAS1237182 (human)2e-206-hydroxyindole sulfate measurement194084720240847203Human
597165182GWAS1261256_Htotal cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS1261256 (human)8e-09blood lipid amount (VT:0003949)blood low density lipoprotein cholesterol level (CMO:0000053)194084720240847203Human
597063807GWAS1159881_Hlung adenocarcinoma QTL GWAS1159881 (human)9e-10lung adenocarcinoma194084720240847203Human
597591156GWAS1648016_Hbronchus cancer QTL GWAS1648016 (human)3e-24bronchus cancer194084720240847203Human
407002281GWAS651257_Hnicotine metabolite ratio QTL GWAS651257 (human)6e-86response to nicotine trait (VT:0010721)194084720240847203Human
597341041GWAS1437115_Hserum alanine aminotransferase measurement QTL GWAS1437115 (human)6e-18serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)194084720240847203Human
597324401GWAS1420475_Hlow density lipoprotein cholesterol measurement QTL GWAS1420475 (human)2e-16low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)194084720240847203Human
597030776GWAS1126850_Htobacco smoke exposure measurement QTL GWAS1126850 (human)6e-25tobacco smoke exposure measurement194084720240847203Human
597612143GWAS1669003_Hinvasive mechanical ventilation QTL GWAS1669003 (human)3e-12invasive mechanical ventilationserum alanine aminotransferase activity level (CMO:0000575)194084720240847203Human
407157687GWAS806663_Hemphysema pattern measurement QTL GWAS806663 (human)0.000001emphysema pattern measurement194084720240847203Human
597063779GWAS1159853_Hlung carcinoma QTL GWAS1159853 (human)5e-19coffee consumption measurement194084720240847203Human
596956521GWAS1076040_Hbitter non-alcoholic beverage consumption measurement QTL GWAS1076040 (human)7e-11upper aerodigestive tract neoplasmdrink intake measurement (CMO:0000771)194084720240847203Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS549493_H GCST003851 Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) 5,323 European ancestry individuals T 0.43 9E-22 21.046 rs56113850 9.59 caffeine metabolite measurement (EFO:0007872)
PMID:27702941
GWAS549496_H GCST003847 Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) 5,353 European ancestry individuals T 0.43 6E-8 7.222 rs56113850 5.43 caffeine metabolite measurement (EFO:0007872)
PMID:27702941
GWAS549497_H GCST003849 Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) 8,911 European ancestry individuals T 0.43 0.000004 5.398 rs56113850 4.59 caffeine metabolite measurement (EFO:0007872)
PMID:27702941
GWAS1643739_H GCST90479563 creatinine (minimum, inv-norm transformed) 117,108 African American or Afro-Caribbean individuals, 57,292 Hispanic or Latin American individuals, 6,305 East Asian ancestry individuals, 421,910 European ancestry individuals T 0.4861 2E-12 11.699 rs56113850 0.01969 obsolete_creatinine measurement (EFO:0004518)
PMID:39024449
GWAS1644073_H GCST90475571 Cancer within the respiratory system (PheCode 165) 14,001 European ancestry cases, 433,059 European ancestry controls T 0.4573 7E-21 20.155 rs56113850 0.1269 PMID:39024449
GWAS1644084_H GCST90475573 Cancer of bronchus; lung (PheCode 165.1) 13,065 European ancestry cases, 434,597 European ancestry controls T 0.4573 3E-21 20.523 rs56113850 0.1325 PMID:39024449
GWAS1644250_H GCST90475559 Asphyxia and hypoxemia (PheCode 1013) 14,950 European ancestry cases, 420,369 European ancestry controls T 0.4575 5E-13 12.302 rs56113850 0.09533 asphyxia (EFO:0009446)
hypoxemia (EFO:0009447)
PMID:39024449
GWAS1126796_H GCST008809 Smoking behaviour (cigarettes smoked per day) up to 153,918 European ancestry individuals C 0.575 3E-68 67.523 rs56113850 0.0719 cigarettes per day measurement (EFO:0006525)
PMID:30679032
GWAS1126850_H GCST008803 Smoking behaviour (cigarette pack-years) up to 150,993 European ancestry individuals C 0.572 6E-25 24.222 rs56113850 0.0385 tobacco smoke exposure measurement (EFO:0009115)
PMID:30679032
GWAS1644619_H GCST90479598 estimated glomerular filtration rate (eGFR, maximum, inv-norm transformed) 110,850 African American or Afro-Caribbean individuals, 55,242 Hispanic or Latin American individuals, 6,249 East Asian ancestry individuals, 398,886 European ancestry individuals T 0.486 5E-12 11.302 rs56113850 0.01983 obsolete_glomerular filtration rate (EFO:0005208)
PMID:39024449
GWAS1130454_H GCST010245 LDL cholesterol levels 440,546 European ancestry individuals T 0.422594 2E-10 9.699 rs56113850 0.013364 low density lipoprotein cholesterol measurement (EFO:0004611)
PMID:32203549
GWAS1647362_H GCST90476037 Dependence on respirator [Ventilator] or supplemental oxygen (PheCode 509.8) 9,729 European ancestry cases, 432,527 European ancestry controls T 0.4575 1E-11 11 rs56113850 0.1109 invasive mechanical ventilation (EFO:0010720)
PMID:39024449
GWAS1647821_H GCST90479761 Asphyxia and hypoxemia (PheCode 1013) 1,922 African American or Afro-Caribbean cases, 117,066 African American or Afro-Caribbean controls, 14,950 European ancestry cases, 420,369 European ancestry controls, 1,220 Hispanic or Latin American cases, 57,306 Hispanic or Latin American controls T 0.485 3E-14 13.523 rs56113850 0.09771 asphyxia (EFO:0009446)
hypoxemia (EFO:0009447)
PMID:39024449
GWAS1648016_H GCST90479789 Cancer of bronchus; lung (PheCode 165.1) 2,647 African American or Afro-Caribbean cases, 118,437 African American or Afro-Caribbean controls, 13,065 European ancestry cases, 434,597 European ancestry controls, 624 Hispanic or Latin American cases, 59,042 Hispanic or Latin American controls T 0.4846 3E-24 23.523 rs56113850 0.1383 PMID:39024449
GWAS1648039_H GCST90479790 Cancer within the respiratory system (PheCode 165) 2,859 African American or Afro-Caribbean cases, 118,073 African American or Afro-Caribbean controls, 14,001 European ancestry cases, 433,059 European ancestry controls, 697 Hispanic or Latin American cases, 58,918 Hispanic or Latin American controls T 0.4846 1E-24 24 rs56113850 0.1344 PMID:39024449
GWAS1139827_H GCST009971 Nicotine metabolite ratio in current smokers 5,185 European ancestry individuals T 0.447 6E-261 260.222 rs56113850 0.682 nicotine metabolite ratio (EFO:0007794)
PMID:32157176
GWAS1139846_H GCST009966 Smoking intensity (cotinine levels/cigarettes per day) 4,772 European ancestry individuals T 0.447 3E-13 12.523 rs56113850 0.155 cotinine measurement (EFO:0007813)
cigarettes per day measurement (EFO:0006525)
PMID:32157176
GWAS1140018_H GCST011702 Smoking cessation 450,129 European ancestry individuals C NR 7E-33 32.155 rs56113850 0.946 smoking cessation (EFO:0004319)
PMID:33082346
GWAS1144712_H GCST012201 Lung adenocarcinoma 15,581 Chinese or European ancestry cases, 27,355 Chinese or European ancestry controls C NR 0.000008 5.097 rs56113850 0.93 lung adenocarcinoma (EFO:0000571)
PMID:32889700
GWAS1144839_H GCST012199 Non-small cell lung cancer 27,120 Chinese or European ancestry cases, 27,355 Chinese or European ancestry controls C NR 3E-9 8.523 rs56113850 0.92 non-small cell lung carcinoma (EFO:0003060)
PMID:32889700
GWAS1652564_H GCST90475197 chloride (minimum, inv-norm transformed) 412,365 European ancestry individuals T 0.4572 4E-11 10.398 rs56113850 0.0191 chloride measurement (EFO:0009284)
PMID:39024449
GWAS1158025_H GCST004750 Squamous cell lung carcinoma 7,426 European ancestry cases, 55,627 European ancestry controls C 0.55529151 7E-11 10.155 rs56113850 1.1555213 squamous cell lung carcinoma (EFO:0000708)
PMID:28604730
GWAS1652685_H GCST90475229 creatinine (mean, inv-norm transformed) 421,411 European ancestry individuals T 0.4572 5E-17 16.302 rs56113850 0.02341 obsolete_creatinine measurement (EFO:0004518)
PMID:39024449
GWAS1652814_H GCST90475280 estimated glomerular filtration rate (eGFR, maximum, inv-norm transformed) 398,886 European ancestry individuals T 0.4571 2E-18 17.699 rs56113850 0.02443 obsolete_glomerular filtration rate (EFO:0005208)
PMID:39024449
GWAS1653103_H GCST90475232 creatinine (minimum, inv-norm transformed) 421,910 European ancestry individuals T 0.4572 2E-20 19.699 rs56113850 0.02611 obsolete_creatinine measurement (EFO:0004518)
PMID:39024449
GWAS1159853_H GCST004748 Lung cancer 29,266 European ancestry cases, 56,450 European ancestry controls C 0.559578448 5E-19 18.302 rs56113850 1.1306498 lung carcinoma (EFO:0001071)
PMID:28604730
GWAS1159881_H GCST004744 Lung adenocarcinoma 11,273 European ancestry cases, 55,483 European ancestry controls C 0.555412481999999 9E-10 9.046 rs56113850 1.121034 lung adenocarcinoma (EFO:0000571)
PMID:28604730
GWAS1653681_H GCST90475282 estimated glomerular filtration rate (eGFR, mean, inv-norm transformed) 398,886 European ancestry individuals T 0.4571 3E-17 16.523 rs56113850 0.02324 obsolete_glomerular filtration rate (EFO:0005208)
PMID:39024449
GWAS1165457_H GCST004749 Lung cancer in ever smokers 23,223 European ancestry cases, 16,964 European ancestry controls C 0.564992436 4E-13 12.398 rs56113850 1.1372905 lung carcinoma (EFO:0001071)
PMID:28604730
GWAS651257_H GCST009922 Nicotine metabolite ratio in current smokers 1,518 Finnish ancestry individuals ? NR 6E-86 85.222 rs56113850 0.653 nicotine metabolite ratio (EFO:0007794)
PMID:26407342
GWAS1664502_H GCST90476388 Do you currently smoke cigarettes? 30,711 European ancestry cases, 135,595 European ancestry controls T 0.4549 6E-19 18.222 rs56113850 0.09176 smoking status measurement (EFO:0006527)
PMID:39024449
GWAS1664505_H GCST90476389 Do you smoke now? 53,560 European ancestry cases, 178,094 European ancestry controls T 0.4561 1E-27 27 rs56113850 0.08818 obsolete_smoking behaviour measurement (EFO:0005671)
PMID:39024449
GWAS1664869_H GCST90476390 How many years have you or did you smoke cigarettes? (inv-normal transformed) 154,894 European ancestry individuals T 0.4551 2E-16 15.699 rs56113850 0.03562 obsolete_smoking behaviour measurement (EFO:0005671)
PMID:39024449
GWAS1669003_H GCST90480265 Dependence on respirator [Ventilator] or supplemental oxygen (PheCode 509.8) 1,765 African American or Afro-Caribbean cases, 118,240 African American or Afro-Caribbean controls, 9,729 European ancestry cases, 432,527 European ancestry controls, 781 Hispanic or Latin American cases, 58,258 Hispanic or Latin American controls T 0.4848 3E-12 11.523 rs56113850 0.108 invasive mechanical ventilation (EFO:0010720)
PMID:39024449
None Available GCST007576 Chronotype 449,734 European ancestry individuals C 0.5769 2E-10 9.699 rs56113850 1.0231643 chronotype measurement (EFO:0008328)
PMID:30696823
None Available GCST008524 Bitter non-alcoholic beverage consumption 85,852 European ancestry individuals C 0.5766 7E-11 10.155 rs56113850 0.0107 bitter non-alcoholic beverage consumption measurement (EFO:0010093)
PMID:31046077
GWAS1210121_H GCST008521 Bitter beverage consumption 85,852 European ancestry individuals C 0.5766 8E-11 10.097 rs56113850 0.0107 bitter beverage consumption measurement (EFO:0010089)
PMID:31046077
GWAS1210515_H GCST008526 Coffee consumption 335,909 European ancestry individuals C 0.5776 8E-16 15.097 rs56113850 0.0121 coffee consumption measurement (EFO:0006781)
PMID:31046077
GWAS734180_H GCST008834 Non-small cell lung cancer 13,327 Chinese ancestry cases, 13,793 European ancestry cases, 13,328 Chinese ancestry controls, 14,027 European ancestry controls C 0.487 3E-9 8.523 rs56113850 1.09 non-small cell lung carcinoma (EFO:0003060)
PMID:31326317
GWAS738935_H GCST010243 Apolipoprotein B levels 439,214 European ancestry individuals T 0.42254 6E-11 10.222 rs56113850 0.0135934 apolipoprotein B measurement (EFO:0004615)
PMID:32203549
GWAS1671367_H GCST90480698 Do you currently smoke cigarettes? 7,968 African American or Afro-Caribbean cases, 14,162 African American or Afro-Caribbean controls, 2,697 Hispanic or Latin American cases, 9,680 Hispanic or Latin American controls, 205 East Asian ancestry cases, 1,052 East Asian ancestry controls, 30,711 European ancestry cases, 135,595 European ancestry controls T 0.4719 7E-15 14.155 rs56113850 0.07402 smoking status measurement (EFO:0006527)
PMID:39024449
GWAS1671370_H GCST90480700 Do you smoke now? 14,691 African American or Afro-Caribbean cases, 23,218 African American or Afro-Caribbean controls, 5,112 Hispanic or Latin American cases, 14,027 Hispanic or Latin American controls, 417 East Asian ancestry cases, 1,539 East Asian ancestry controls, 53,560 European ancestry cases, 178,094 European ancestry controls T 0.4763 1E-26 26 rs56113850 0.08033 obsolete_smoking behaviour measurement (EFO:0005671)
PMID:39024449
GWAS1218517_H GCST90455518 Lung cancer 39,664 European ancestry cases, 119,158 European ancestry controls, 2,438 African ancestry cases, 62,112 African ancestry controls T 0.449 1E-43 43 rs56113850 0.889 PMID:39366959
GWAS1218697_H GCST90455519 Lung adenocarcinoma (conditioned on cigarettes per day) 13,292 European ancestry cases, 67,596 European ancestry controls, 595 African ancestry cases, 62,112 African ancestry controls T 0.452 3E-21 20.523 rs56113850 0.887 lung adenocarcinoma (EFO:0000571)
PMID:39366959
GWAS1219389_H GCST90455520 Squamous cell lung carcinoma (conditioned on cigarettes per day) 8,901 European ancestry cases, 64,477 European ancestry controls, 300 African ancestry cases, 62,112 African ancestry controls T 0.451 6E-21 20.222 rs56113850 0.866 squamous cell lung carcinoma (EFO:0000708)
PMID:39366959
GWAS1232455_H GCST90102815 3-methylxanthine levels 8,809 European ancestry individuals T NR 2E-24 23.699 rs56113850 0.155 3-methylxanthine measurement (EFO:0021175)
PMID:35050183
GWAS1236327_H GCST90103295 X-21286 levels 8,809 European ancestry individuals T NR 8E-12 11.097 rs56113850 0.104 X-21286 measurement (EFO:0800804)
PMID:35050183
GWAS1237182_H GCST90245090 6-hydroxyindole sulfate levels 14,296 European ancestry individuals T 0.4287 2E-20 19.699 rs56113850 0.09685272 6-hydroxyindole sulfate measurement (EFO:0801004)
PMID:36357675
GWAS1237778_H GCST90103258 X-12216 levels 8,809 European ancestry individuals T NR 4E-20 19.398 rs56113850 0.139 X-12216 measurement (EFO:0021294)
PMID:35050183
GWAS769654_H GCST003264 Post bronchodilator FEV1/FVC ratio 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals T 0.462 5E-9 8.302 rs56113850 0.014 FEV/FVC ratio (EFO:0004713)
response to bronchodilator (GO:0097366)
PMID:26634245
GWAS770249_H GCST003262 Post bronchodilator FEV1 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals T 0.458 2E-8 7.699 rs56113850 0.067 forced expiratory volume (EFO:0004314)
response to bronchodilator (GO:0097366)
PMID:26634245
GWAS770796_H GCST003629 Nicotine metabolite ratio in current smokers 437 European ancestry individuals, 364 African American individuals, 453 Latino individuals, 674 Japanese American individuals, 311 Native Hawaiian ancestry individuals T NR 1E-50 50 rs56113850 0.3644 nicotine metabolite ratio (EFO:0007794)
PMID:27488534
None Available GCST90092866 Triglyceride levels in large LDL 115,082 European ancestry individuals T 0.420796 2E-8 7.699 rs56113850 0.0230106 triglyceride measurement (EFO:0004530)
low density lipoprotein cholesterol measurement (EFO:0004611)
PMID:35213538
GWAS1248779_H GCST90092863 Concentration of large LDL particles 115,082 European ancestry individuals T 0.420796 1E-8 8 rs56113850 0.0237825 low density lipoprotein cholesterol measurement (EFO:0004611)
PMID:35213538
None Available GCST90092887 Concentration of LDL particles 115,082 European ancestry individuals T 0.420796 1E-8 8 rs56113850 0.0237631 low density lipoprotein cholesterol measurement (EFO:0004611)
PMID:35213538
GWAS1255724_H GCST90092809 Apolipoprotein B levels 115,082 European ancestry individuals T 0.420796 9E-9 8.046 rs56113850 0.0239612 apolipoprotein B measurement (EFO:0004615)
PMID:35213538
GWAS1255995_H GCST90092820 Glycine levels 114,978 European ancestry individuals T 0.420828 3E-8 7.523 rs56113850 0.0218076 glycine measurement (EFO:0009767)
PMID:35213538
GWAS806663_H GCST002525 Local histogram emphysema pattern 3,732 European ancestry smoker individuals, 2,724 European ancestry chronic obstructive pulmonary disease smoker cases, 2,372 African American smoker individuals, 786 African American chronic obstructive pulmonary disease smoker cases T 0.4 0.000001 6 rs56113850 0.02 emphysema pattern measurement (EFO:0005850)
PMID:25006744
GWAS808345_H GCST002525 Local histogram emphysema pattern 3,732 European ancestry smoker individuals, 2,724 European ancestry chronic obstructive pulmonary disease smoker cases, 2,372 African American smoker individuals, 786 African American chronic obstructive pulmonary disease smoker cases T 0.40 1E-9 9 rs56113850 0.02 emphysema pattern measurement (EFO:0005850)
PMID:25006744
GWAS1258522_H GCST90092880 Linoleic acid levels 115,006 European ancestry individuals T 0.420788 6E-9 8.222 rs56113850 0.0239432 linoleic acid measurement (EFO:0006807)
PMID:35213538
GWAS1261256_H GCST90092968 Cholesterol levels in small VLDL 115,082 European ancestry individuals T 0.420796 8E-9 8.097 rs56113850 0.0240384 total cholesterol measurement (EFO:0004574)
obsolete_vldl cholesterol measurement (EFO:0008317)
PMID:35213538
None Available GCST90092976 Phospholipid levels in small VLDL 115,082 European ancestry individuals T 0.420796 3E-8 7.523 rs56113850 0.0231974 obsolete_vldl cholesterol measurement (EFO:0008317)
phospholipid measurement (EFO:0004639)
PMID:35213538
None Available GCST90092963 Concentration of small LDL particles 115,082 European ancestry individuals T 0.420796 8E-9 8.097 rs56113850 0.0241421 low density lipoprotein cholesterol measurement (EFO:0004611)
PMID:35213538
None Available GCST90092972 Free cholesterol levels in small VLDL 115,082 European ancestry individuals T 0.420796 2E-8 7.699 rs56113850 0.0235212 free cholesterol measurement (EFO:0008591)
obsolete_vldl cholesterol measurement (EFO:0008317)
PMID:35213538
None Available GCST90092962 Total lipid levels in small LDL 115,082 European ancestry individuals T 0.420796 1E-8 8 rs56113850 0.0237331 low density lipoprotein cholesterol measurement (EFO:0004611)
lipid measurement (EFO:0004529)
PMID:35213538
GWAS1263352_H GCST90018942 Serum alkaline phosphatase levels 344,292 European ancestry individuals, 118,886 East Asian ancestry individuals C NR 1E-89 89 rs56113850 0.0472 alkaline phosphatase measurement (EFO:0004533)
PMID:34594039
GWAS1267493_H GCST90179151 Cigarettes smoked per day (MTAG) 337,334 European ancestry individuals T NR 2E-78 77.699 rs56113850 0.04714 cigarettes per day measurement (EFO:0006525)
PMID:36376304
GWAS1272321_H GCST90243987 Cigarettes smoked per day 783,784 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals C 0.55 3E-214 213.523 rs56113850 0.0534 cigarettes per day measurement (EFO:0006525)
PMID:36477530
GWAS1275804_H GCST90269559 Glycine levels (UKB data field 23462) 88,258 European ancestry individuals T 0.420048 7E-10 9.155 rs56113850 0.0279433 glycine measurement (EFO:0009767)
PMID:36764567
GWAS1279859_H GCST90199654 Paraxanthine levels 7,840 European ancestry individuals C 0.573947 3E-12 11.523 rs56113850 0.111197 paraxanthine measurement (EFO:0021178)
PMID:36635386
None Available GCST90199944 Indolin-2-one levels 7,027 European ancestry individuals C 0.570252 2E-24 23.699 rs56113850 0.167321 indolin-2-one measurement (EFO:0800981)
PMID:36635386
GWAS1283197_H GCST90243988 Smoking cessation 1,400,535 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals C 0.563 1E-120 120 rs56113850 0.0303 smoking cessation (EFO:0004319)
PMID:36477530
GWAS1283287_H GCST90200562 X-21286 levels 8,231 European ancestry individuals C 0.576068 2E-19 18.699 rs56113850 0.136846 X-21286 measurement (EFO:0800804)
PMID:36635386
None Available GCST90200573 X-18935 levels 4,952 European ancestry individuals C 0.606272 8E-11 10.097 rs56113850 0.131701 X-18935 measurement (EFO:0800798)
PMID:36635386
GWAS1284359_H GCST90200483 X-12216 levels 8,181 European ancestry individuals C 0.577382 7E-18 17.155 rs56113850 0.129952 X-12216 measurement (EFO:0021294)
PMID:36635386
GWAS1284585_H GCST90199644 Theobromine levels 8,137 European ancestry individuals C 0.576193 1E-11 11 rs56113850 0.105914 theobromine measurement (EFO:0021179)
PMID:36635386
GWAS1285157_H GCST90200002 6-hydroxyindole sulfate levels 8,229 European ancestry individuals C 0.57613 6E-13 12.222 rs56113850 0.109573 6-hydroxyindole sulfate measurement (EFO:0801004)
PMID:36635386
GWAS1304141_H GCST90044900 Plasma letrozole concentrations in letrozole treated hormone-receptor-positive breast cancer 228 European ancestry individuals T 0.46 2E-13 12.699 rs56113850 4693.72 response to aromatase inhibitor (GO:0061477)
PMID:34096894
None Available GCST012213 Aerodigestive squamous cell cancer (pleiotropy) 7,426 European ancestry lung squamous cell carcinoma cases, 5,452 European ancestry oral and oropharynx squamous cell carcinoma cases, 693 European ancestry laryngeal squamous cell carcinoma cases, 316 European ancestry esophageal squamous cell carcinoma cases, 61,961 European ancestry controls T 0.41 7E-11 10.155 rs56113850 0.9 upper aerodigestive tract neoplasm (EFO:0004284)
PMID:33667223
GWAS1314180_H GCST011754 Nicotine dependence 46,213 European ancestry individuals, 11,787 African American individuals T NR 4E-16 15.398 rs56113850 0.031 nicotine dependence (EFO:0003768)
PMID:33144568
GWAS1321615_H GCST007464 Smoking cessation (MTAG) up to 820,192 European ancestry individuals C 0.567 6E-10 9.222 rs56113850 0.00974331 smoking cessation (EFO:0004319)
PMID:30643251
GWAS1322631_H GCST007459 Smoking behaviour (cigarettes smoked per day) up to 377,334 European ancestry individuals C 0.555 4E-99 98.398 rs56113850 0.0523096 cigarettes per day measurement (EFO:0006525)
PMID:30643251
GWAS1322646_H GCST007460 Smoking cessation up to 547,219 European ancestry individuals C 0.567 2E-48 47.699 rs56113850 0.05760633 smoking cessation (EFO:0004319)
PMID:30643251
GWAS1327581_H GCST007463 Cigarettes smoked per day (MTAG) up to 403,928 European ancestry individuals C 0.555 5E-58 57.302 rs56113850 0.0361686 cigarettes per day measurement (EFO:0006525)
PMID:30643251
GWAS1078207_H GCST011125 Caffeine consumption from coffee 373,522 European ancestry individuals T 0.421821 5E-19 18.302 rs56113850 0.02071 coffee consumption measurement (EFO:0006781)
PMID:33287642
GWAS915492_H GCST011126 Caffeine consumption from coffee or tea 362,316 European ancestry individuals T 0.421755 2E-29 28.699 rs56113850 0.02649 coffee consumption measurement (EFO:0006781)
tea consumption measurement (EFO:0010091)
PMID:33287642
GWAS1344049_H GCST90061018 Nicotine metabolite ratio in current smokers 389 European ancestry individuals C NR 7E-22 21.155 rs56113850 0.671 nicotine metabolite ratio (EFO:0007794)
PMID:34599228
GWAS1344050_H GCST90061019 Nicotine metabolite ratio in current smokers 541 European ancestry individuals C NR 1E-37 37 rs56113850 0.748 nicotine metabolite ratio (EFO:0007794)
PMID:34599228
None Available GCST90019492 Alanine aminotransferase levels 342,387 European ancestry individuals, 6,017 African ancestry individuals, 7,325 South Asian ancestry individuals C NR 3E-12 11.523 rs56113850 0.0167 serum alanine aminotransferase measurement (EFO:0004735)
PMID:33462484
GWAS1350094_H GCST90013405 Liver enzyme levels (alanine transaminase) 437,267 European ancestry individuals T 0.422385 1E-15 15 rs56113850 0.00312488 serum alanine aminotransferase measurement (EFO:0004735)
PMID:33972514
None Available GCST90092970 Cholesteryl ester levels in small VLDL 115,082 European ancestry individuals T 0.420796 8E-9 8.097 rs56113850 0.0240607 cholesteryl ester measurement (EFO:0010351)
obsolete_vldl cholesterol measurement (EFO:0008317)
PMID:35213538
GWAS1354794_H GCST90093034 Total lipid levels in very small VLDL 115,082 European ancestry individuals T 0.420796 4E-8 7.398 rs56113850 0.0224965 obsolete_vldl cholesterol measurement (EFO:0008317)
lipid measurement (EFO:0004529)
PMID:35213538
None Available GCST90239670 Non-HDL cholesterol levels 1,320,016 European ancestry individuals C 0.562613 2E-13 12.699 rs56113850 0.014895 non-high density lipoprotein cholesterol measurement (EFO:0005689)
PMID:34887591
None Available GCST90093036 Phospholipid levels in very small VLDL 115,082 European ancestry individuals T 0.420796 1E-8 8 rs56113850 0.0234529 obsolete_vldl cholesterol measurement (EFO:0008317)
phospholipid measurement (EFO:0004639)
PMID:35213538
GWAS1355332_H GCST90092964 Phospholipid levels in small LDL 115,082 European ancestry individuals T 0.420796 4E-9 8.398 rs56113850 0.0243826 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipid measurement (EFO:0004639)
PMID:35213538
GWAS1355743_H GCST90093035 Concentration of very small VLDL particles 115,082 European ancestry individuals T 0.420796 7E-9 8.155 rs56113850 0.0238214 obsolete_vldl cholesterol measurement (EFO:0008317)
PMID:35213538
None Available GCST90093032 Free cholesterol levels in very small VLDL 115,082 European ancestry individuals T 0.420796 2E-8 7.699 rs56113850 0.0231331 free cholesterol measurement (EFO:0008591)
obsolete_vldl cholesterol measurement (EFO:0008317)
PMID:35213538
None Available GCST90094735 F-chocolate/coffee liking (derived food-liking factor) 158,905 European ancestry individuals C 0.5774 1E-9 9 rs56113850 0.090892 taste liking measurement (EFO:0010155)
PMID:35585065
GWAS1363428_H GCST90239655 Low density lipoprotein cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 3E-17 16.523 rs56113850 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
PMID:34887591
None Available GCST90134662 Lung adenocarcinoma 9,791 European ancestry cases, 23,173 European ancestry controls, 4,630 East Asian ancestry cases, 5,372 East Asian ancestry controls, 844 African American cases, 3,774 African American controls ? NR 8E-11 10.097 rs56113850 0.07 lung adenocarcinoma (EFO:0000571)
PMID:35915169
GWAS1364041_H GCST90134663 Squamous cell lung carcinoma 6,107 European ancestry cases, 23,173 European ancestry controls, 1,292 East Asian ancestry cases, 5,372 East Asian ancestry controls, 451 African American cases, 3,774 African American controls ? NR 3E-11 10.523 rs56113850 0.09 squamous cell lung carcinoma (EFO:0000708)
PMID:35915169
GWAS1365651_H GCST90134661 Lung cancer 26,683 European ancestry cases, 25,278 European ancestry controls, 7,062 East Asian ancestry cases, 5,372 East Asian ancestry controls, 1,987 African American cases, 3,774 African American controls ? NR 8E-27 26.097 rs56113850 0.08 lung carcinoma (EFO:0001071)
PMID:35915169
GWAS1371220_H GCST90132984 Coffee consumption (cups per day) 448,204 European ancestry individuals T 0.422202 8E-19 18.097 rs56113850 0.0186901 coffee consumption measurement (EFO:0006781)
PMID:32193382
GWAS1374561_H GCST90140773 Indolin-2-one levels 6,136 Finnish ancestry individuals C NR 7E-15 14.155 rs56113850 0.17 indolin-2-one measurement (EFO:0800981)
PMID:35347128
GWAS1374566_H GCST90140807 6-hydroxyindole sulfate levels 6,136 Finnish ancestry individuals C NR 2E-11 10.699 rs56113850 0.12 6-hydroxyindole sulfate measurement (EFO:0801004)
PMID:35347128
None Available GCST90140661 Theobromine levels 6,136 Finnish ancestry individuals C NR 3E-12 11.523 rs56113850 0.13 theobromine measurement (EFO:0021179)
PMID:35347128
None Available GCST90140662 Paraxanthine levels 6,136 Finnish ancestry individuals C NR 2E-19 18.699 rs56113850 0.17 paraxanthine measurement (EFO:0021178)
PMID:35347128
GWAS1375693_H GCST90140675 3-methylxanthine levels 6,136 Finnish ancestry individuals C NR 9E-18 17.046 rs56113850 0.16 3-methylxanthine measurement (EFO:0021175)
PMID:35347128
GWAS1377089_H GCST90140391 X-12216 levels 6,136 Finnish ancestry individuals C NR 3E-15 14.523 rs56113850 0.15 X-12216 measurement (EFO:0021294)
PMID:35347128
None Available GCST90092810 Ratio of apolipoprotein B to apolipoprotein A1 levels 115,082 European ancestry individuals T 0.420796 3E-8 7.523 rs56113850 0.0227187 apolipoprotein A 1 measurement (EFO:0004614)
apolipoprotein B measurement (EFO:0004615)
PMID:35213538
GWAS1403539_H GCST90100220 Estimated glomerular filtration rate (creatinine) 1,205,871 European ancestry individuals, 168,300 East Asian ancestry individuals, 63,553 African ancestry individuals, 23,509 Hispanic or Latin American individuals, 22,103 African American individuals, 21,791 Central Asian or South Asian ancestry individuals, 1,502 Middle Eastern ancestry individuals, 939 other admixed ancestry individuals, 602 Native American ancestry individuals, 150 Asian ancestry individuals, 339 individuals C 0.5599 9E-13 12.046 rs56113850 7.151 obsolete_glomerular filtration rate (EFO:0005208)
PMID:35710981
GWAS1408320_H GCST90266536 Urine X-21831 levels in chronic kidney disease 4,599 European ancestry individuals C 0.59 8E-31 30.097 rs56113850 0.469 X-21831 measurement (EFO:0800832)
PMID:37277652
GWAS1409088_H GCST90266210 Urine X-12126 levels in chronic kidney disease 4,891 European ancestry individuals C 0.58 3E-14 13.523 rs56113850 0.189 X-12126 measurement (EFO:0800708)
PMID:37277652
None Available GCST90266218 Plasma X-12216 levels in chronic kidney disease 4,797 European ancestry individuals C 0.59 8E-12 11.097 rs56113850 0.173 X-12216 measurement (EFO:0021294)
PMID:37277652
GWAS1409168_H GCST90266467 Urine X-18935 levels in chronic kidney disease 4,893 European ancestry individuals C 0.58 1E-29 29 rs56113850 0.294 X-18935 measurement (EFO:0800798)
PMID:37277652
GWAS1412597_H GCST90245663 X-21286 levels 14,296 European ancestry individuals T 0.4289 7E-38 37.155 rs56113850 0.13240077 X-21286 measurement (EFO:0800804)
PMID:36357675
None Available GCST90245023 3-hydroxycotinine glucuronide levels 14,296 European ancestry individuals T 0.4184 3E-15 14.523 rs56113850 0.26954755 3-hydroxycotinine glucuronide measurement (EFO:0800984)
PMID:36357675
GWAS1414446_H GCST90245527 X-12126 levels 14,296 European ancestry individuals T 0.4165 6E-26 25.222 rs56113850 0.1277143 X-12126 measurement (EFO:0800708)
PMID:36357675
GWAS1415161_H GCST90245264 Indolin-2-one levels 14,296 European ancestry individuals T 0.4373 1E-30 30 rs56113850 0.1445022 indolin-2-one measurement (EFO:0800981)
PMID:36357675
GWAS1417167_H GCST90245533 X-12216 levels 14,296 European ancestry individuals T 0.4278 7E-35 34.155 rs56113850 0.1274714 X-12216 measurement (EFO:0021294)
PMID:36357675
GWAS1417546_H GCST90245453 Theobromine levels 14,296 European ancestry individuals T 0.4286 8E-20 19.097 rs56113850 0.09372097 theobromine measurement (EFO:0021179)
PMID:36357675
GWAS1417981_H GCST90244877 1,7-dimethylurate levels 14,296 European ancestry individuals T 0.4287 3E-24 23.523 rs56113850 0.10510567 1,7-dimethylurate measurement (EFO:0021512)
PMID:36357675
GWAS1419401_H GCST90239667 Non-HDL cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 2E-14 13.699 rs56113850 N/A non-high density lipoprotein cholesterol measurement (EFO:0005689)
PMID:34887591
GWAS1419596_H GCST90245043 3-methylxanthine levels 14,296 European ancestry individuals T 0.4288 3E-44 43.523 rs56113850 0.14389715 3-methylxanthine measurement (EFO:0021175)
PMID:36357675
GWAS1420018_H GCST90245365 Paraxanthine levels 14,296 European ancestry individuals T 0.4292 1E-26 26 rs56113850 0.11057526 paraxanthine measurement (EFO:0021178)
PMID:36357675
GWAS1420475_H GCST90239658 Low density lipoprotein cholesterol levels 1,320,016 European ancestry individuals C 0.567435 2E-16 15.699 rs56113850 0.0142152 low density lipoprotein cholesterol measurement (EFO:0004611)
PMID:34887591
GWAS1425804_H GCST90300043 Metabolite levels (hydroxycotinine) 2,414 European, Hispanic or African American individuals C 0.5489 2E-12 11.699 rs56113850 0.2 hydroxycotinine measurement (EFO:0800964)
PMID:37253714
GWAS1428703_H GCST90243976 Cigarettes smoked per day 618,489 European ancestry individuals C 0.565 6E-207 206.222 rs56113850 0.0557 cigarettes per day measurement (EFO:0006525)
PMID:36477530
GWAS1429826_H GCST90243980 Smoking cessation 1,147,272 European ancestry individuals C 0.572 5E-114 113.302 rs56113850 0.0303 smoking cessation (EFO:0004319)
PMID:36477530
None Available GCST90179146 C-reactive protein levels (MTAG) 575,531 European ancestry individuals T NR 8E-16 15.097 rs56113850 0.01645 C-reactive protein measurement (EFO:0004458)
PMID:36376304
GWAS1437115_H GCST90428729 Alanine aminotransferase levels 1,010,710 European ancestry individuals T NR 6E-18 17.222 rs56113850 0.0034 serum alanine aminotransferase measurement (EFO:0004735)
PMID:38632349
Database Acc Id Source(s)
GWAS Catalog GCST008803 GWAS Catalog

RGD Curation Notes
Note Type Note Reference