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References
References - curated
Region Genes in Region
RGD ID | Symbol | Name | Chr | Start | Stop | Species | 1606741 | HYKK | hydroxylysine kinase | 15 | 78507577 | 78537373 | Human | |
Position Markers
Peak: (rs8034191) |
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QTLs in Region (GRCh38)
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Additional Information
GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog | ![]() |
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The highlighted row represents the current QTL |
QTL | GWAS Catalog Study | Disease Trait | Study Size | Risk Allele | Risk Allele Frequency | P Value | P Value MLOG | Peak Marker | Reported Odds Ratio or Beta-coefficient | Ontology Accession | PubMed |
GWAS1116532_H | GCST003266 | Pre bronchodilator FEV1 | 6,659 European ancestry current and former smoker individuals | ? | NR | 3E-9 | 8.523 | rs8034191 | 0.07893 | forced expiratory volume (EFO:0004314) |
PMID:26634245 |
GWAS1116542_H | GCST003267 | Pre bronchodilator FEV1/FVC ratio | 6,659 European ancestry current and former smoker individuals | ? | NR | 2E-10 | 9.699 | rs8034191 | 0.01688 | FEV/FVC ratio (EFO:0004713) |
PMID:26634245 |
GWAS1116891_H | GCST003265 | Post bronchodilator FEV1/FVC ratio in COPD | 5,439 European ancestry current and former smoker cases, 821 African American current and former smoker cases | T | 0.403 | 3E-7 | 6.523 | rs8034191 | 0.013 | FEV/FVC ratio (EFO:0004713) response to bronchodilator (GO:0097366) |
PMID:26634245 |
GWAS1126794_H | GCST008809 | Smoking behaviour (cigarettes smoked per day) | up to 153,918 European ancestry individuals | C | 0.341 | 1E-139 | 139 | rs8034191 | 0.0956 | cigarettes per day measurement (EFO:0006525) |
PMID:30679032 |
GWAS1126805_H | GCST008803 | Smoking behaviour (cigarette pack-years) | up to 150,993 European ancestry individuals | C | 0.338 | 6E-118 | 117.222 | rs8034191 | 0.0819 | tobacco smoke exposure measurement (EFO:0009115) |
PMID:30679032 |
GWAS613956_H | GCST003262 | Post bronchodilator FEV1 | 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals | T | 0.335 | 1E-13 | 13 | rs8034191 | 0.07 | forced expiratory volume (EFO:0004314) response to bronchodilator (GO:0097366) |
PMID:26634245 |
GWAS668710_H | GCST000459 | Lung cancer | 1,952 European ancestry cases, 1,438 European ancestry controls | ? | NR | 3E-26 | 25.523 | rs8034191 | 1.29 | lung carcinoma (EFO:0001071) |
PMID:19654303 |
GWAS669258_H | GCST000170 | Lung cancer | 1,926 European ance other ancestry cases, 2,522 European and other ancestry controls | C | 0.34 | 5E-20 | 19.302 | rs8034191 | 1.3 | lung carcinoma (EFO:0001071) |
PMID:18385738 |
GWAS669263_H | GCST000172 | Lung cancer | 1,154 European ancestry cases, 1,137 European ancestry controls | G | NR | 3E-18 | 17.523 | rs8034191 | 1.3 | lung carcinoma (EFO:0001071) |
PMID:18385676 |
GWAS670100_H | GCST000359 | Chronic obstructive pulmonary disease | 823 cases, 810 controls | C | 0.33 | 1E-10 | 10 | rs8034191 | 1.4 | chronic obstructive pulmonary disease (EFO:0000341) |
PMID:19300482 |
GWAS690404_H | GCST000233 | Lung cancer | 194 European ancestry cases, 219 European ancestry controls | G | NR | 1E-8 | 8 | rs8034191 | 1.38 | lung carcinoma (EFO:0001071) |
PMID:18780872 |
GWAS1225232_H | GCST012716 | ICD10 Z72.0: Tobacco use | 7,432 individuals | ? | NR | 6E-7 | 6.222 | rs8034191 | N/A | cigarettes per day measurement (EFO:0006525) |
PMID:29758381 |
GWAS809701_H | GCST003264 | Post bronchodilator FEV1/FVC ratio | 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals | T | 0.331 | 6E-14 | 13.222 | rs8034191 | 0.014 | FEV/FVC ratio (EFO:0004713) response to bronchodilator (GO:0097366) |
PMID:26634245 |
GWAS1300565_H | GCST011021 | Intracranial aneurysm | 7,495 European ancestry cases, 3,259 East Asian ancestry cases, 71,934 European ancestry controls, 234,948 East Asian ancestry controls | T | 0.676 | 3E-8 | 7.523 | rs8034191 | 0.117 | brain aneurysm (EFO:0003870) |
PMID:33199917 |
GWAS1314179_H | GCST011754 | Nicotine dependence | 46,213 European ancestry individuals, 11,787 African American individuals | T | NR | 1E-70 | 70 | rs8034191 | 0.06 | nicotine dependence (EFO:0003768) |
PMID:33144568 |
RGD Curation Notes
Note Type | Note | Reference |
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