GWAS1126800_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1126800_H (tobacco smoke exposure measurement QTL GWAS1126800 (human)) Homo sapiens

Symbol: GWAS1126800_H
Name: tobacco smoke exposure measurement QTL GWAS1126800 (human)
RGD ID: 597030726
Trait: tobacco smoke exposure measurement
LOD Score: Not Available
P Value: 2.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382105,352,905 - 105,352,906RGD_MAPPER_PIPELINEGRCh38
GRCh372105,969,362 - 105,969,363RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1126800_HHumantobacco smoke exposure measurement  IAGPrs62155873405850206 GWAS_CATALOGPMID:30679032
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1604297C2orf49chromosome 2 open reading frame 492105337540105385899Human

Position Markers

Peak: (rs62155873)
Human AssemblyChrPosition (strand)Source
GRCh382105,352,905 - 105,352,906RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597179225GWAS1275299_Hsmoking initiation QTL GWAS1275299 (human)4e-21smoking initiation2105352905105352906Human
1298432OSTEAR10_HOsteoarthritis QTL 10 (human)2.340.0001Joint/bone inflammationdistal interphalangeal joint osteoarthritis297592766106657498Human
597030726GWAS1126800_Htobacco smoke exposure measurement QTL GWAS1126800 (human)2e-09tobacco smoke exposure measurement2105352905105352906Human
597051890GWAS1147964_Hsmoking status measurement QTL GWAS1147964 (human)5e-10smoking status measurement2105352905105352906Human
597228576GWAS1324650_Hself reported educational attainment QTL GWAS1324650 (human)2e-12self reported educational attainment2105352905105352906Human
597124862GWAS1220936_Hattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement QTL GWAS1220936 (human)3e-08attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement2105352905105352906Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1126800_H GCST008803 Smoking behaviour (cigarette pack-years) up to 150,993 European ancestry individuals T 0.127 2E-9 8.699 rs62155873 0.0334 tobacco smoke exposure measurement (EFO:0009115)
 PMID:30679032
GWAS1147964_H GCST007085 Smoking status approximately 458,000 European ancestry individuals ? NR 5E-10 9.302 rs62155873 N/A smoking status measurement (EFO:0006527)
 PMID:30595370
GWAS1220936_H GCST90061435 Externalizing behaviour (multivariate analysis) up to 53,293 European ancestry Attention-deficit/hyperactivity disorder individuals, up to 164,684 European ancestry problematic alcohol use individuals, up to 186,875 European ancestry lifetime cannabis use individuals, up to 357,187 European ancestry individuals measuring reverse-coded age at first sexual intercourse, up to 336,121 European ancestry individuals measuring number of sexual partners, up to 426,379 European ancestry individuals measuring general risk tolerance, up to 1,251,809 European ancestry individuals measuring lifetime smoking initiation C 0.877 3E-8 7.523 rs62155873 0.01 attention deficit hyperactivity disorder (EFO:0003888)
obsolete_antisocial behaviour measurement (EFO:0007052)
 PMID:34446935
GWAS1275299_H GCST90243985 Smoking initiation 3,382,012 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals T 0.109 4E-21 20.398 rs62155873 0.0118 smoking initiation (EFO:0005670)
 PMID:36477530
GWAS1324650_H GCST006442 Educational attainment (years of education) up to 1,131,881 European ancestry individuals T 0.1221 2E-12 11.699 rs62155873 0.0151 self reported educational attainment (EFO:0004784)
 PMID:30038396
Database Acc Id Source(s)
GWAS Catalog GCST008803 GWAS Catalog

RGD Curation Notes
Note Type Note Reference