Bmd84 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bmd84 (Bone mineral density QTL 84) Rattus norvegicus

Symbol: Bmd84
Name: Bone mineral density QTL 84
RGD ID: 5684993
Trait: tibia mineral mass   (VT:1000283)    
Measurement Type: bone mineral content   (CMO:0001554)    
LOD Score: 4.1
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2842,692,684 - 50,095,447RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0846,588,437 - 54,065,241RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0845,061,464 - 52,686,094RGDRnor5.0
RGSC_v3.4845,291,674 - 53,049,477RGDRGSC3.4
Cross Type: Not Available
Strains Crossed: GK/KyoSwe F344/DuCrlSwe 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
bone mineral content  IDA 5684953update to tibia specific termRGD 

Experimental Condition
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
control condition  IDA 5684953 RGD 

Measurement Method
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
dual-energy x-ray absorptiometry  IDA 5684953 RGD 

Rat Strain
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
F344/DuCrlSwe  IEA 5684953 RGD 
GK/KyoSwe  IEA 5684953 RGD 

Vertebrate Trait
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
tibia mineral mass  IDA 5684953 RGD 

Disease Annotations     Click to see Annotation Detail View
osteoporosis  (IAGP)

Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
F344/DuCrlSwe  (IEA)
GK/KyoSwe  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Identification of candidate gene regions in the rat by co-localization of QTLs for bone density, size, structure and strength. Lagerholm S, etal., PLoS One. 2011;6(7):e22462. Epub 2011 Jul 27.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
41090425LOC120094489small nucleolar RNA SNORA1784269549242695620Rat
1309824Tectatectorin alpha84270796242779726Rat
1308880Tbceltubulin folding cofactor E-like84279564842854552Rat
7503878LOC102549755uncharacterized LOC10254975584287104742877228Rat
41398114LOC120094129uncharacterized LOC12009412984289401742900855Rat
2734Grik4glutamate ionotropic receptor kainate type subunit 484290304343331990Rat
41372312Rpl10-ps5ribosomal protein L10, pseudogene 584313522443135987Rat
1305111Arhgef12Rho guanine nucleotide exchange factor 1284335007043475404Rat
1565079Tlcd5TLC domain containing 584348138843486288Rat
621691Pou2f3POU class 2 homeobox 384349540843577795Rat
1305890Oafout at first homolog84359436243612334Rat
1307858Trim29tripartite motif-containing 2984368222143706992Rat
41272318LOC120094130uncharacterized LOC12009413084378126843800378Rat
7617270LOC102555063uncharacterized LOC10255506384382301643830274Rat
11511573LOC108351687uncharacterized LOC10835168784383129143835286Rat
41073558LOC120094131uncharacterized LOC12009413184396438143966974Rat
620791Nectin1nectin cell adhesion molecule 184410177644164863Rat
41291834LOC120094415U6 spliceosomal RNA84425965444259757Rat
11384736LOC108351689uncharacterized LOC10835168984431212444316357Rat
3860Thy1Thy-1 cell surface antigen84438949544394688Rat
621073Usp2ubiquitin specific peptidase 284441145744439668Rat
1307477Mfrpmembrane frizzled-related protein84444563644450859Rat
1308802C1qtnf5C1q and TNF related 584445093444453075Rat
1305953Rnf26ring finger protein 2684445455144456745Rat
41046946LOC120094132uncharacterized LOC12009413284446930544475593Rat
620463Mcammelanoma cell adhesion molecule84447939144487575Rat
1561386CblCbl proto-oncogene84448782444571620Rat
1305351Ccdc153coiled-coil domain containing 15384457652844584345Rat
1559807Nherf4NHERF family PDZ scaffold protein 484458439044588838Rat
1311293Nlrx1NLR family member X184458847644606678Rat
1305840Abcg4ATP binding cassette subfamily G member 484461118744629818Rat
1311492Hinfphistone H4 transcription factor84463433344644288Rat
1310281C2cd2lC2CD2-like84464807444658856Rat
735124Dpagt1dolichyl-phosphate N-acetylglucosaminephosphotransferase 184466405544671102Rat
1566119H2axH2A.X variant histone84467192744673257Rat
2801Hmbshydroxymethylbilane synthase84467355444680950Rat
1308038Vps11VPS11 core subunit of CORVET and HOPS complexes84468376844698572Rat
621146Hyou1hypoxia up-regulated 184470607344718189Rat
62066Slc37a4solute carrier family 37 member 484472321644729301Rat
1302991Trappc4trafficking protein particle complex subunit 484472945844733285Rat
621043Rps25ribosomal protein s2584473362344735999Rat
1597440Cenataccentrosomal AT-AC splicing factor84473596844742859Rat
1591087Mettl9-ps1methyltransferase like 9, pseudogene 184474565544746391Rat
1309739Foxr1forkhead box R184476058744768696Rat
1597393Upk2uroplakin 284477919844781190Rat
41204644LOC120094346WW domain-binding protein 11-like84480920044815162Rat
1309096Bcl9lBCL9 like84481197744840611Rat
62010Cxcr5C-X-C motif chemokine receptor 584484209844858425Rat
41365399LOC120094133uncharacterized LOC12009413384488317244886607Rat
1564560Ddx6DEAD-box helicase 684493112744967773Rat
61831Trehtrehalase84499018245003881Rat
11482331LOC10835169160S ribosomal protein L35a pseudogene84499214544992574Rat
620878Phldb1pleckstrin homology-like domain, family B, member 184500353845051541Rat
41329639LOC120094134uncharacterized LOC12009413484500826045008955Rat
1359110Arcn1archain 184505761745082224Rat
1307682Ift46intraflagellar transport 4684508159345104052Rat
1596132Tmem25transmembrane protein 2584510711645112657Rat
1359544Ttc36tetratricopeptide repeat domain 3684511273745116345Rat
1586165Kmt2alysine methyltransferase 2A84511677145193320Rat
40971005LOC120094493U2 spliceosomal RNA84516929845169488Rat
41216140LOC120094525U6atac minor spliceosomal RNA84520816045208283Rat
40984864Trnas-aga38transfer RNA serine (anticodon AGA) 3884521065545210729Rat
1303259Atp5mgATP synthase membrane subunit g84522675045233582Rat
1303173Ube4aubiquitination factor E4A84523602245278129Rat
41346119Piga-ps1phosphatidylinositol glycan anchor biosynthesis, class A, pseudogene 184526742445268174Rat
1307718Cd3gCD3 gamma subunit of T-cell receptor complex84528079745287271Rat
2304Cd3dCD3 delta subunit of T-cell receptor complex84528780345293342Rat
1309222Cd3eCD3 epsilon subunit of T-cell receptor complex84530384845315297Rat
1307196Mpzl2myelin protein zero-like 284534828545359298Rat
1310980Mpzl3myelin protein zero-like 384536047545380662Rat
41230475LOC120094459small nucleolar RNA SNORA4184537514745375278Rat
1562572Jamljunction adhesion molecule like84538483645415459Rat
41000181LOC1200945105S ribosomal RNA84540918945409294Rat
3633Scn2bsodium voltage-gated channel beta subunit 284542562945437765Rat
631404Scn4bsodium voltage-gated channel beta subunit 484544658045462294Rat
1305033Tmprss4transmembrane serine protease 484547581945508409Rat
41395099LOC120094136uncharacterized LOC12009413684553156745539351Rat
7587328Smim35small integral membrane protein 3584554971045558135Rat
620138Il10rainterleukin 10 receptor subunit alpha84556300945578041Rat
1559602Gstp1-ps4glutathione S-transferase pi 1, pseudogene 484560982745610741Rat
1310872Tmprss13transmembrane serine protease 1384562575945653943Rat
41127481LOC120094137uncharacterized LOC12009413784566652745670587Rat
69315Fxyd6FXYD domain-containing ion transport regulator 684567905445705958Rat
2173Fxyd2FXYD domain-containing ion transport regulator 284571288745720032Rat
1304887Dscaml1DS cell adhesion molecule-like 184574029846057322Rat
1561243Cep164centrosomal protein 16484607090146134511Rat
2191Bace1beta-secretase 184614206046166268Rat
1307500Rnf214ring finger protein 21484616626946202048Rat
3275Pcsk7proprotein convertase subtilisin/kexin type 784620207946224699Rat
3723Taglntransgelin84622493946230413Rat
1308311Sidt2SID1 transmembrane family, member 284623237946248913Rat
41323129LOC120094332uncharacterized LOC12009433284624639946259868Rat
620332Pafah1b2platelet-activating factor acetylhydrolase 1b, catalytic subunit 284626006946312073Rat
41024980Rps26-ps6ribosomal protein S26, pseudogene 684628687546288369Rat
1593938Sik3SIK family kinase 384631225346522444Rat
40954807LOC120094333uncharacterized LOC12009433384633539646337233Rat
41023870Pou5f1-ps1POU class 5 homeobox 1, pseudogene 184644880646457521Rat
2130Apoa1apolipoprotein A184652725146529035Rat
2136Apoc3apolipoprotein C384653147846533658Rat
2132Apoa4apolipoprotein A484653908346541464Rat
70903Apoa5apolipoprotein A584656118046563818Rat
1562173Zpr1ZPR1 zinc finger84656489846574719Rat
1308076Bud13BUD13 homolog84657512446590964Rat
1561633LOC500990similar to RIKEN cDNA 4931429L1584659524946610558Rat
41348957LOC120094520small nucleolar RNA SNORA1784687192046872035Rat
7680811LOC102549886uncharacterized LOC10254988684692025646924107Rat
41252071Rps29-ps2ribosomal protein S29, pseudogene 284693760146937865Rat
41192037LOC120094138uncharacterized LOC12009413884703821847043573Rat
11443679LOC108351693uncharacterized LOC10835169384705985747061895Rat
7655349LOC102550073uncharacterized LOC10255007384708587347088770Rat
41018096LOC120094369uncharacterized LOC12009436984719339647199371Rat
41130355LOC120094139uncharacterized LOC12009413984725160147256876Rat
41389139LOC120094559U6 spliceosomal RNA84734545847345564Rat
41338585LOC120094483small nucleolar RNA SNORA4884771752047717649Rat
7621914LOC102551354uncharacterized LOC10255135484784442847847847Rat
1310999Cadm1cell adhesion molecule 184784783648178703Rat
7627355LOC102550632uncharacterized LOC10255063284791529847953291Rat
40969508LOC120094335uncharacterized LOC12009433584808010448106686Rat
7531008LOC102550769uncharacterized LOC10255076984821884048226958Rat
41400266LOC120094370uncharacterized LOC12009437084832711148329606Rat
1560781Nxpe4neurexophilin and PC-esterase domain family member 484850269748744101Rat
41403974LOC120094142uncharacterized LOC12009414284851642348530457Rat
2323193Nxpe2neurexophilin and PC-esterase domain family, member 284866170848695555Rat
41160523LOC120094141uncharacterized LOC12009414184869727848697867Rat
41152571LOC120094140uncharacterized LOC12009414084872258448730793Rat
1566243Nxpe1neurexophilin and PC-esterase domain family, member 184874925048773762Rat
1304874Rexo2RNA exonuclease 284881190048823622Rat
1308017Rbm7RNA binding motif protein 784883189448838399Rat
1563941C8h11orf71similar to human chromosome 11 open reading frame 7184883855648838970Rat
1309606Nnmtnicotinamide N-methyltransferase84892866348947734Rat
41362515LOC120094143uncharacterized LOC12009414384893598248941209Rat
727921Zbtb16zinc finger and BTB domain containing 1684898937649177011Rat
41199271LOC120094144uncharacterized LOC12009414484909029449092983Rat
61818Htr3a5-hydroxytryptamine receptor 3A84924201849254475Rat
40961893LOC120094145uncharacterized LOC12009414584924565249247685Rat
61820Htr3b5-hydroxytryptamine receptor 3B84927929149308444Rat
1311555Usp28ubiquitin specific peptidase 2884932576649386229Rat
40966354Pclaf-ps4PCNA clamp associated factor, pseudogene 484935425549354590Rat
2322263Cldn25claudin 2584939197549392664Rat
1309197Zw10zw10 kinetochore protein84939654149424743Rat
628625Tmprss5transmembrane serine protease 584943732149461395Rat
41387742LOC120094541U4 spliceosomal RNA84957462049574709Rat
2520Drd2dopamine receptor D284970890349772888Rat
1305538Ankk1ankyrin repeat and kinase domain containing 184977986249788024Rat
1303264Ttc12tetratricopeptide repeat domain 1284979991649847940Rat
7643606LOC102555969uncharacterized LOC10255596984984690849849158Rat
7668475LOC102556026uncharacterized LOC10255602684985101049858172Rat
41168094LOC120094371uncharacterized LOC12009437184985945649862516Rat
67378Ncam1neural cell adhesion molecule 184986562950165687Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10177D8Mit721384653163946531840Ratregion
10178D8Wox413084653172246531840Ratregion
33887D8Mit315084269268442692818Ratregion
33973D8Mit219485009524950095447Ratregion
34116D8Mgh1213684600883646008974Ratregion
11322D8Hmgc112184622932246229437Ratregion
36309D8Rat4115584762723547627390Ratregion
35184D8Rat19713784574208945742223Ratregion
36872D8Rat4311284863013148630243Ratregion
37038D8Rat4015984671094046711092Ratregion
36739D8Rat4212184843265248432767Ratregion
35098D8Rat3917684635847846358654Ratregion
38072D8Rat8512384653171846531839Ratregion
40708D8Rat15822284781361647813826Ratregion
38920D8Rat6310784787206947872172Ratregion
39108D8Rat9410384955855049558653Ratregion
41922D8Rat4517484426012244260298Ratregion
42238D8Arb2728584652799946528287Ratregion
42246D8Arb717084653173346531902Ratregion
42248D8Arb823684439230744392577Ratregion
42852D8Rat18716984677001446770168Ratregion
42853D8Rat21520485008859850088795Ratregion
42351D8Rat23323884287899542879227Ratregion
42352D8Rat23222684291394142914164Ratregion
42467D1Rat40523884903006949030308Ratregion
40830D8Rat16021184396996243970185Ratregion
40860D8Rat16113284360449843604640Ratregion
44400D8Got6119484334552543345719Ratregion
44401D8Got6222484453143044531654Ratregion
44402D8Got7013084762725547627385Ratregion
44403D8Got7117984627297046273149Ratregion
44404D8Got6923884621468946214929Ratregion
44406D8Got6622684583605445836280Ratregion
44407D8Got6427784709498947095266Ratregion
44408D8Got6522984701018447010413Ratregion
44409D8Got6713184744643547446562Ratregion
44411D8Got7217784914781249147989Ratregion
44412D8Got7423584962554049625775Ratregion
44413D8Got7324184968514849685391Ratregion
60639D8Got6318884450980644509994Ratregion
44856D11Got6829184862107248621363Ratregion
1303358D8Got30224484553930945539553Ratregion
67240D8Arb1031584986865249868967Ratregion
67248D8Arb2330784986865249868959Ratregion
67777D8Uwm114984587409345874250Ratregion
1627847D8Got35916784770687447707043Ratregion
1629797D8Got32429884709498147095279Ratregion
1638505D8Got35517184879556248795733Ratregion
1632801D8Wox3484439232144392645Ratregion
1635389D8Got33315284916636449166511Ratregion
1636609D8Got34415484656406146564213Ratregion
2301434D8Chm1145784329616943296654Ratregion
7205840Apoa121884652751246528429Ratregion
7192154Drd219884977252749772725Ratregion
7206428Hinfp21884463635144636569Ratregion
5035803PMC193673P121284623051746230729Ratregion
5035847PMC22863P164984439285644393505Ratregion
5035919PMC308923P186084467667844677538Ratregion
7206404mMaCIR130157784908896749090544Ratregion
5036263Drd2108384977175449772836Ratregion
5039186RH12756121584472898244729197Ratregion
5036446Pafah1b212484626231446262438Ratregion
5035671WI-1239412684505763245057758Ratregion
5025980RH13044021884530392045304138Ratregion
5028881RH14268112984866181848661947Ratregion
5028901RH14275514284449409644494238Ratregion
5034315Treh31684499820744998523Ratregion
5029151RH14370910184616702046167121Ratregion
5029209RH14393110484348147743481581Ratregion
5031864AU04689712584680683346806958Ratregion
5034534BE11919217284650296246503134Ratregion
5034644BF39066815784601599446016151Ratregion
5029287RH14422718184556072945560910Ratregion
5034726BI28261620584535897745359182Ratregion
5032219AI74745113084626230446262434Ratregion
5026974RH13424319284987861649878808Ratregion
5029731BE10218415784616841146168568Ratregion
5032513RH12699922384810931148109534Ratregion
5027105STS-Z408366184468417544684236Ratregion
5029767BF38713416784477919944779366Ratregion
5032635RH13473418584445059644450781Ratregion
5029955BF40013817285006211150062283Ratregion
5030041AW53111618584335319343353378Ratregion
5035306AW52968516184815958248159743Ratregion
5025052AW5498179784484183044841927Ratregion
5030339BF40266623484815809248158326Ratregion
5025248RH12758519784359444143594638Ratregion
5033311RH13836915184581183445811985Ratregion
5025314RH12784219284448803944488231Ratregion
5025694RH12930018184467089044671071Ratregion
5030889BF41118011684870872148708837Ratregion
5025802RH12973219284607104446071236Ratregion
5052099RH9483910384467372344673827Ratregion
5052103RH9484121384439388644394099Ratregion
5055149RH14363412784522678745226914Ratregion
5055925RH14408218684972643049726616Ratregion
5056087RH14417513584465100744651142Ratregion
5056099RH14418227684346745343467729Ratregion
5053897RH14291410184898977048989871Ratregion
5053945RH14294117384523853945238712Ratregion
5054273RH14313022985006962250069851Ratregion
5057249AA92606519584510374645103941Ratregion
5055375RH14376524384627523146275474Ratregion
5057818BF38620318484465367644653860Ratregion
5058606BE10218215684657017246570328Ratregion
5058820BI28466318184466275444662935Ratregion
5056589RH14446515784784680947846966Ratregion
5052486AU04101616484500364145003805Ratregion
5058890BI27815420084500372545003925Ratregion
5059024BF38738717784703825047038427Ratregion
5055729RH14396811384290528142905394Ratregion
5058418AI05890811284541564745415759Ratregion
5053283RH14255918784769801447698201Ratregion
5059348AI05915318184651851346519408Ratregion
5053699RH14280013484559848045598614Ratregion
5049838RH13371118384927861849278801Ratregion
5049988RH13379721784766364347663860Ratregion
7193108DRD29184976434249765360Ratregion
7193129DRD220884976430649765441Ratregion
5052589RH12573324984870623948706488Ratregion
5050958RH13435620784653161946532796Ratregion
5051002RH13438122084624674746246967Ratregion
5050598RH13414919084744544447445634Ratregion
5050852RH13429520784977261949772826Ratregion
5040700RH12843318084445467544454855Ratregion
5040846RH12851720684626011046260316Ratregion
5043644RH13014418084622441546224595Ratregion
5045374RH13114118484473602744736284Ratregion
5041684RH12899916384523609545236258Ratregion
5041884RH12911415084473004544730195Ratregion
5046344RH13169818184883939548839576Ratregion
5045340RH13112121684708595747086173Ratregion
5045344RH13112421684858658648586802Ratregion
5045880RH13143222084467090144671121Ratregion
5047858RH13256919384991527149915464Ratregion
5046634RH13186618584616567646165861Ratregion
5046668RH13188618784546193745462124Ratregion
5046704RH13190719684779777447797970Ratregion
5046818RH13197218084522568445225864Ratregion
5042120RH12925119684359444043594636Ratregion
5047352RH132278084416453544164749Ratregion
5048390RH13287618884877347348773661Ratregion
5039906RH12797621384468416444684377Ratregion
5048510RH13294518184883264148832822Ratregion
5040166RH12812720284570552145705723Ratregion
5042224RH12931118284445284044453022Ratregion
5040362RH12823920884467291944673127Ratregion
5040510RH12832518884654125446541442Ratregion
5043078RH12981818384459007844590261Ratregion
5043122RH12984418984607096246071151Ratregion
5042476RH12945720584472883644729041Ratregion
5042610RH12953820084467059644670796Ratregion
5041004RH12860821484467367844673892Ratregion
5043658RH13015219484881204748812241Ratregion
5043892RH13028919784652219446522385Ratregion
5043068RH12981318384616063946160822Ratregion
5075128RH13841420284541530745415509Ratregion
5073936RH13772420884872850448728712Ratregion
5075264RH13849416384463174544631909Ratregion
5075480RH13861820384620808746208290Ratregion
5075702RH13874718284409590444096086Ratregion
5075778RH13879123784899193748992175Ratregion
5075830RH13882112584616264346162768Ratregion
5072520RH13689718584458409144584276Ratregion
5074388RH13798821184495939644959607Ratregion
5076048RH13894916684987692449877090Ratregion
5076334RH13911512784870736848707495Ratregion
5072632RH13696216684623239646232562Ratregion
5076612RH13927716784846626248466429Ratregion
5074878RH13827024984984739449848783Ratregion
5076192RH13903215584449538044495535Ratregion
5077576RH13983519884657326946573467Ratregion
5079544RH14105921584622503446225249Ratregion
5076354RH13912712784656317546563302Ratregion
5079762RH14118821284571947845719950Ratregion
5078018RH14009420084986733749867537Ratregion
5078800RH140559084500857345008882Ratregion
5080148RH14141319884626155346261751Ratregion
5079168RH14077517184335266543352836Ratregion
5073246RH13732518284443968044439862Ratregion
5073978RH13774813784856084148560978Ratregion
5067208AU04789617584503561045035780Ratregion
5067230AU04788324884503561945035865Ratregion
5070079RH9446017784654100846541185Ratregion
5070081RH9446118684652899446529180Ratregion
5070370AI8462548884652232646522414Ratregion
5060174BI27962219184465100744651198Ratregion
5060192BI27969420384370651043706713Ratregion
5061844AW53386215384345545943455611Ratregion
5062096BF39743214084516820545168345Ratregion
5062276BE10646718884444822544448413Ratregion
5064176BE12072017284818730348187475Ratregion
5065732BF40631315984893907448939233Ratregion
5065280BE12137220684415518244155389Ratregion
5062354BE10659115384502386745024020Ratregion
5065636BE10950915284448896444489116Ratregion
5060752BF38908320784855988648560093Ratregion
5066076BF4133169484938172249381816Ratregion
5061014BF38970216084652110146521261Ratregion
5063230BI28954021284538022345380435Ratregion
5066458AU04834523684781373447813972Ratregion
5061564BF40204514684988183849881984Ratregion
5086861AI00765516484335513143355296Ratregion
5086875AI41273316084815685348157013Ratregion
5082029BF40911422284946378049464002Ratregion
5086319BQ19210020184942442749424628Ratregion
5086359BM38495416784977992149780088Ratregion
5087090BE10699918584910192049102105Ratregion
5087325BQ19390319684892893148929127Ratregion
5087396AI71714122084616625546166475Ratregion
5082593BE11981217884543348445433662Ratregion
5089913AU04943813384868248348682616Ratregion
5089925AU04944518684894185548942041Ratregion
5083201BF39097716884279675642796924Ratregion
5083749AA80068817484347936343479537Ratregion
5088823AU04879221684644704946447265Ratregion
5081775BE11816316884447627344476441Ratregion
5082049BF40920014184875604148756182Ratregion
5082123BF4097729484285256542852659Ratregion
5082157BI28007617584370669143706866Ratregion
5082227BI27429921884415491744155135Ratregion
5088491AU04860127184694593846946209Ratregion
5085163BE09637116884439378644393954Ratregion
5090315AU04967819184397975443979947Ratregion
5085471BM38312119984484211244842311Ratregion
5082661BE11995215684725665947256815Ratregion
5085810BF38814916784988413649884303Ratregion
5085908AA87500418484659068246590866Ratregion
5080922RH14186019984850408648504285Ratregion
5086301AW52974117284415769144157863Ratregion
5086353BM38567718084547587545476055Ratregion
5084804AI10285418184336312643363307Ratregion
5086483BM38576617084926385649264026Ratregion
5083391BF39103817684544238745442563Ratregion
5086821BE11467115584982622149826376Ratregion
5503410D1S285441684989811849898532Ratregion
5507701UNH19182884589910945899937Ratregion
5505120Tagln27584622635146226728Ratregion
5505347Upk287984478024444781123Ratregion
5505528RH67992101884716686247167880Ratregion
5505480REN7341925484663037946630633Ratregion
5505482REN7377622684672354046723766Ratregion
5506648ECD0116187884661050846611386Ratregion
5506783G4530018084484943544849615Ratregion
5499679MARC_7597-7598:992008547:116784622544346226299Ratregion
5500009UniSTS:2361188184854094548541026Ratregion
5499647MARC_6495-6496:992007247:1084650621246506714Ratregion
5501155PMC150745P218084622585546226403Ratregion
5502601RH12550315884359497443595132Ratregion
5500681RH13663218984817587348176062Ratregion
5501383Lep130884647960146480909Ratregion
5501395Mll180784515454745155354Ratregion
5501814MARC_13871-13872:1007494510:1112784976671049767837Ratregion
5502050MARC_26154-26155:1030452349:1115184468967644690827Ratregion
5507247BB2395408384605711946057202Ratregion
5502323RH12447018284474621944746512Ratregion
Position Markers

Flank 1: (D8Mit3)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2842,692,684 - 42,692,818 (+)MAPPER
Rnor_6.0846,588,437 - 46,588,570NCBI
Rnor_5.0845,061,464 - 45,061,597UniSTS
RGSC_v3.4845,291,674 - 45,291,808RGD
RGSC_v3.4845,291,675 - 45,291,808UniSTS
RGSC_v3.1845,300,440 - 45,300,574RGD
Celera842,285,573 - 42,285,706UniSTS
RH 3.4 Map8410.8UniSTS
RH 3.4 Map8410.8RGD
Cytogenetic Map8 RGD
Peak: (D8Mit2)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2850,095,249 - 50,095,447 (+)MAPPER
Rnor_6.0854,065,044 - 54,065,241NCBI
Rnor_5.0852,685,897 - 52,686,094UniSTS
RGSC_v3.4853,049,279 - 53,049,477RGD
RGSC_v3.4853,049,280 - 53,049,477UniSTS
RGSC_v3.1853,068,254 - 53,068,551RGD
Celera849,646,904 - 49,647,101UniSTS
RH 3.4 Map8537.5UniSTS
RH 3.4 Map8537.5RGD
RH 2.0 Map8403.3RGD
Cytogenetic Map8q23UniSTS
Flank 2: (D8Mit2)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2850,095,249 - 50,095,447 (+)MAPPER
Rnor_6.0854,065,044 - 54,065,241NCBI
Rnor_5.0852,685,897 - 52,686,094UniSTS
RGSC_v3.4853,049,279 - 53,049,477RGD
RGSC_v3.4853,049,280 - 53,049,477UniSTS
RGSC_v3.1853,068,254 - 53,068,551RGD
Celera849,646,904 - 49,647,101UniSTS
RH 3.4 Map8537.5UniSTS
RH 3.4 Map8537.5RGD
RH 2.0 Map8403.3RGD
Cytogenetic Map8q23UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8470581049705810Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)8768895552688955Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)8873663553736635Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82266233067662330Rat
2303564Gluco43Glucose level QTL 433blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82613018771130187Rat
2303572Insul13Insulin level QTL 132blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)82613018771130187Rat
1359021Bp271Blood pressure QTL 2711.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82664491246711092Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)82720571554998217Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)82824291253961020Rat
1300146Rf17Renal function QTL 172.9renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)82824291273242912Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
2302278Gluco36Glucose level QTL 364.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82950266550095447Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)82950266570386295Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
61337Bp22Blood pressure QTL 225.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815442692818Rat
1331744Bp217Blood pressure QTL 2173.398arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815458482492Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83084815482460899Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83084815482460899Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83084815482460899Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83084815482460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83555193880551938Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84071306682925667Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84071306693965294Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)84186687675097878Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
631216Stl9Serum triglyceride level QTL 94.710.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)84186701070386132Rat
5684993Bmd84Bone mineral density QTL 844.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)84269268450095447Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088624Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)84653172299083736Rat
1582229Stl20Serum triglyceride level QTL 203.20.0033blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)84863013149147989Rat
2303570Gluco48Glucose level QTL 482blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)84980583194805831Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85009524982460899Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85009524982460899Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general number of animals used: 19 parental GK, 20 parental F344, 37 F1 and 206 F2 rats 5684953
qtl_general lineage: F1 animals from both the reciprocal crosses were used; 2 seperate F2 intercrosses were generated, one from grandmaternal GK and grandpaternal F344, the other from grandmaternal F344 and grandpaternal GK 5684953
qtl_general measurement method: at 215 days (mean age) rats kept under controlled conditions were sacrificed and left tibia was subjected to two-dimensional dual energy X-ray absorptiometry using a PIXImusTM densitometer (GE Lunar, Madison, WI) 5684953
qtl_general software used: bone mineral content measured using GE Lunar software 5684953
qtl_general this region (35-58 cM) is determined in grandmaternal F344/grandpaternal GK and grandmaternal GK/grandpaternal F344 F2 male rats 5684953