Bss99 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Bss99 (Bone structure and strength QTL 99) Rattus norvegicus

Symbol: Bss99
Name: Bone structure and strength QTL 99
RGD ID: 5684963
Trait: tibia area   (VT:1000281)    
Measurement Type: tibia area measurement   (CMO:0001382)    
LOD Score: 3.1
P Value: Not Available
Variance: Not Available
Position No map positions available.
Cross Type: Not Available
Strains Crossed: GK/KyoSwe F344/DuCrlSwe 

Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
tibia area measurement  IDA 5684953 RGD 

Experimental Condition
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
control condition  IDA 5684953 RGD 

Measurement Method
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
dual-energy x-ray absorptiometry  IDA 5684953 RGD 

Rat Strain
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
F344/DuCrlSwe  IEA 5684953 RGD 
GK/KyoSwe  IEA 5684953 RGD 

Vertebrate Trait
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
tibia area  IDA 5684953 RGD 

Disease Annotations     Click to see Annotation Detail View
osteopetrosis  (IAGP)

Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait
tibia area  (IDA)

Rat Strain
F344/DuCrlSwe  (IEA)
GK/KyoSwe  (IEA)


References - curated
# Reference Title Reference Citation
1. Identification of candidate gene regions in the rat by co-localization of QTLs for bone density, size, structure and strength. Lagerholm S, etal., PLoS One. 2011;6(7):e22462. Epub 2011 Jul 27.


Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (D6Mgh11)
Rat AssemblyChrPosition (strand)Source
RH 3.4 Map6288.5UniSTS
RH 3.4 Map6288.5RGD
RH 2.0 Map6454.4RGD
Cytogenetic Map6 RGD
Flank 2: (D3Mit19)
Rat AssemblyChrPosition (strand)Source
RGSC_v3.1698,838,518 - 98,838,852RGD

Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general number of animals used: 19 parental GK, 20 parental F344, 37 F1 and 206 F2 rats 5684953
qtl_general lineage: F1 animals from both the reciprocal crosses were used; 2 seperate F2 intercrosses were generated, one from grandmaternal GK and grandpaternal F344, the other from grandmaternal F344 and grandpaternal GK 5684953
qtl_general measurement method: at 215 days (mean age) rats kept under controlled conditions were sacrificed and left tibia was subjected to two-dimensional dual energy X-ray absorptiometry using a PIXImusTM densitometer (GE Lunar, Madison, WI) 5684953
qtl_general software used: user-defined region of bone area measured using GE Lunar software 5684953
qtl_general this region (30-60 cM) is determined in grand-maternal F344 and grand-paternal GK F2 male rats 5684953