Bss92 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Bss92 (Bone structure and strength QTL 92) Rattus norvegicus

Symbol: Bss92
Name: Bone structure and strength QTL 92
RGD ID: 4889951
Trait: tibia area   (VT:1000281)    
Measurement Type: tibia-fibula cortical bone total cross-sectional area   (CMO:0001721)    
LOD Score: 3.9
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21482,057,471 - 95,876,975RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01487,458,772 - 106,641,756RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01481,093,112 - 106,705,037RGDRnor5.0
RGSC_v3.41487,960,277 - 102,509,397RGDRGSC3.4
Cross Type: Not Available
Strains Crossed: GK/KyoSwe F344/DuCrlSwe 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
osteoporosis  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Measurement Method

Vertebrate Trait
tibia area  (IDA)

Rat Strain
F344/DuCrlSwe  (IEA)
GK/KyoSwe  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Genetic loci for bone architecture determined by three-dimensional CT in crosses with the diabetic GK rat. Lagerholm S, etal., Bone. 2010 Dec;47(6):1039-47. Epub 2010 Aug 10.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2494Ddcdopa decarboxylase148637868586469189Rat
2874Igfbp3insulin-like growth factor binding protein 3148205634782064083Rat
619736Rab1aRAB1A, member RAS oncogene family149442221994448799Rat
3072Mdh1malate dehydrogenase 1149563062595645920Rat
69230Ppp3r1protein phosphatase 3, regulatory subunit B, alpha149155674391606391Rat
2543Egfrepidermal growth factor receptor149117697991349722Rat
1305566Upp1uridine phosphorylase 1148380949583829299Rat
1307414Lgalslgalectin-like149499699195004499Rat
727882Pno1partner of NOB1 homolog149160971191618280Rat
735146Slc1a4solute carrier family 1 member 4149453080194560190Rat
1305895Abca13ATP binding cassette subfamily A member 13148387339784376138Rat
1310210Ugp2UDP-glucose pyrophosphorylase 2149545633095497483Rat
1311199Peli1pellino E3 ubiquitin protein ligase 1149525427495309168Rat
1310826Actr2actin related protein 2149429644394333735Rat
1312002Coblcordon-bleu WH2 repeat protein148682813787060682Rat
1308373Cnrip1cannabinoid receptor interacting protein 1149146287791492739Rat
1309304Spred2sprouty-related, EVH1 domain containing 2149414921094250787Rat
1309101Cep68centrosomal protein 68149444797394470533Rat
1307112Fignl1fidgetin-like 1148636867086381728Rat
1308269Plekpleckstrin149139701591429693Rat
1309870Spmip7sperm microtubule inner protein 7148603042786085644Rat
1309501WdpcpWD repeat containing planar cell polarity effector149564595595977120Rat
628718Vps54VPS54 subunit of GARP complex149537882195455871Rat
1563985Zpbpzona pellucida binding protein148583097186030778Rat
1564049Sertad2SERTA domain containing 2149473363794838200Rat
1311920Aftphaftiphilin149487142994925625Rat
1563863Dnaaf10dynein axonemal assembly factor 10149161864991639828Rat
1564174Tns3tensin 3148317364983405671Rat
1309073Fbxo48F-box protein 48149138085791382314Rat
1566234Grb10growth factor receptor bound protein 10148649505186602800Rat
1587626C14h7orf57similar to human chromosome 7 open reading frame 57148374847883768293Rat
1586609Mospd1l1motile sperm domain containing 1 like 1148228693982289413Rat
1564724Pkd1l1polycystin 1 like 1, transient receptor potential channel interacting148355296483670062Rat
1562979Ikzf1IKAROS family zinc finger 1148625506586340839Rat
1560957Etaa1ETAA1 activator of ATR kinase149229846192314044Rat
1560600C1dC1D nuclear receptor corepressor149166095191673177Rat
1563894Morf4l1-ps5mortality factor 4 like 1, pseudogene 5148495712984958164Rat
1582940Srbd1-ps1S1 RNA binding domain 1, pseudogene 1148786397287874151Rat
1561286Gapdh-ps102Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 102148800930188010396Rat
1589624Vwc2von Willebrand factor C domain containing 2148568367085825068Rat
1591358Tmem161bl1transmembrane protein 161B148399138583992860Rat
1585482Meis1Meis homeobox 1149315542693294373Rat
1589907Rpl38-ps2ribosomal protein L38, pseudogene 2149439999594400277Rat
1596197Vstm2aV-set and transmembrane domain containing 2A149066001290897561Rat
1596170Sec61gSec61 translocon subunit gamma149089976690906143Rat
1591079Rps2-ps39ribosomal protein S2, pseudogene 39149398860293989324Rat
1591975Sun3Sad1 and UNC84 domain containing 3148371013683748982Rat
1591976Hus1HUS1 checkpoint clamp component148368870283703466Rat
1597113Pgm1-ps1phosphoglucomutase 1, pseudogene 1148609106086093503Rat
2318182Apoo-ps3apolipoprotein O, pseudogene 3148248730382487888Rat
2320735Pom121l12POM121 transmembrane nucleoporin-like 12148910853589109604Rat
2320935Prmt1l1protein arginine methyltransferase 1 like 1148755116587552305Rat
2323208Hnrnpk-ps1heterogeneous nuclear ribonucleoprotein K, pseudogene 1149175662891758358Rat
2323556Rnf115-ps1ring finger protein 115, pseudogene 1148932518989326067Rat
2323677Rps27-ps8ribosomal protein S27, pseudogene 8149435080494399082Rat
2323894Glo1-ps2glyoxalase 1, pseudogene 2148903118089037851Rat
7502494LOC102553003uncharacterized LOC102553003148692803886948136Rat
7662247LOC102552528uncharacterized LOC102552528148577231185787440Rat
7628157LOC102549056uncharacterized LOC102549056149509482895099101Rat
7582242LOC102547136uncharacterized LOC102547136149518434595189240Rat
7606982LOC102551829uncharacterized LOC102551829149390812293910470Rat
7567433LOC102548772uncharacterized LOC102548772149500327895033943Rat
7704924LOC102547058uncharacterized LOC102547058149516702395169167Rat
7731769LOC102553529uncharacterized LOC102553529148848792688503110Rat
7743232LOC102552764uncharacterized LOC102552764148661986086627072Rat
7747850LOC102547925uncharacterized LOC102547925149465505494664167Rat
9301616LOC103693204uncharacterized LOC103693204149330204293310404Rat
9391524LOC103693208uncharacterized LOC103693208149466620894674847Rat
11455995Rps28-ps5ribosomal protein S28, pseudogene 5149493747794937817Rat
11466963LOC108352806uncharacterized LOC108352806149341156093421104Rat
11457748LOC108352794uncharacterized LOC108352794148272684082779159Rat
11364710Trnar-ucu6transfer RNA arginine (anticodon UCU) 6148713816287138247Rat
11437269LOC108352797uncharacterized LOC108352797148487819784931496Rat
11372689LOC108352800uncharacterized LOC108352800148755321287569267Rat
11400929Rps12l10ribosomal protein S12 like 10149501796395020005Rat
11402271LOC10835285860S ribosomal protein L35a pseudogene148385728083857747Rat
11509257LOC108352807uncharacterized LOC108352807149456056994568126Rat
41137280LOC120096688uncharacterized LOC120096688149500443595007530Rat
41202877LOC120096773U7 small nuclear RNA148268554882685609Rat
41168377LOC120096740U6 spliceosomal RNA148833653488336640Rat
41249970Trnap-agg79transfer RNA proline (anticodon AGG) 79149426147894261558Rat
41172352LOC120096681uncharacterized LOC120096681149413848594146076Rat
41280378LOC12009665960S ribosomal protein L36-like148337163683371941Rat
41173477LOC120096788small nucleolar RNA SNORA24148598480185984933Rat
41119964LOC120096820small nucleolar RNA SNORA17149538853095388662Rat
41149863LOC120096775U7 small nuclear RNA148268562382685685Rat
41096592LOC120096679uncharacterized LOC120096679149401636694022660Rat
41369426LOC120096673uncharacterized LOC120096673149145269291489124Rat
41347538LOC120096660uncharacterized LOC120096660148329955083312397Rat
41348836LOC120096676uncharacterized LOC120096676149189758991906807Rat
41196480LOC120096761U6 spliceosomal RNA149430763594307740Rat
41231038LOC120096684uncharacterized LOC120096684149433374194338506Rat
41164776Gapdh-ps48Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 48148389039283895380Rat
40977515LOC120096678uncharacterized LOC120096678149311603393147067Rat
41014016LOC120096689uncharacterized LOC120096689149505924895114522Rat
40926375LOC120096680uncharacterized LOC120096680149412774594137748Rat
41014043LOC120096821small nucleolar RNA SNORA17148731226387312390Rat
40958885Gapdh-ps46Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 46148908863989089742Rat
40984137LOC120096862U4 spliceosomal RNA149199894591999070Rat
40961538LOC120096666uncharacterized LOC120096666148636582486368551Rat
41008896Rpl9-ps27ribosomal protein L9, pseudogene 27148571020685718895Rat
41010079Actr1a-ps1actin related protein 1A, pseudogene 1149427561694280123Rat
41078953LOC120096539uncharacterized LOC120096539148453086384531858Rat
41028118LOC120096667uncharacterized LOC120096667148642547786445651Rat
41256134LOC120096664uncharacterized LOC120096664148603994486053196Rat
41054942LOC120096840small nucleolar RNA ACA64148732777187327909Rat
41222219Hnrnpc-ps1heterogeneous nuclear ribonucleoprotein C, pseudogene 1148307259183073569Rat
41062800LOC120096671uncharacterized LOC120096671149000679690019183Rat
41018088LOC120096677uncharacterized LOC120096677149235369992358109Rat
41041262LOC120096789small nucleolar RNA SNORA44148934494589345050Rat
41021963Gapdh-ps47Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 47148952183889522809Rat
41311414Carhsp1-ps1calcium regulated heat stable protein 1, pseudogene 1149074204590752015Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10773D14Mit10260148205747182057735Ratregion
33965D14Mit15193148361068083610873Ratregion
36307D14Rat21141149119526891195399Ratregion
37660D14Rat49153149174233591742498Ratregion
35897D14Rat22178149587680595876975Ratregion
38016D14Rat51193148346063583460830Ratregion
40406D14Rat109136149384310293843234Ratregion
40140D14Rat95173149502301895023211Ratregion
38806D14Rat67145148347125583471397Ratregion
39030D14Rat38200149255388692554092Ratregion
39310D14Rat34228149034862590348856Ratregion
42394D14Rat137219148439090184391119Ratregion
42395D14Rat138130149466695094667080Ratregion
42396D14Rat139213149347693093477141Ratregion
41138D14Rat94235148336806283368335Ratregion
45190D14Got66177148728538687285563Ratregion
45191D14Got63193148833061688331125Ratregion
45191D14Got63193148833093288331125Ratregion
45192D14Got67171148813325988133432Ratregion
45194D14Got6594148708200187082095Ratregion
45205D14Got87158148337426483374424Ratregion
45206D14Got62200148634847786348674Ratregion
45207D14Got64159148597384085974001Ratregion
60076D14Got79249149202972492029973Ratregion
60077D14Got81136149377560093775732Ratregion
60078D14Got83217149054282590543039Ratregion
60079D14Got84189149223454292234733Ratregion
60080D14Got85140149294484492944980Ratregion
60082D14Got88146149295700892957154Ratregion
625817D14Got82295149308583193086126Ratregion
62442D14Uia3195148625840386258598Ratregion
66465D14Mco15229148205748682057735Ratregion
66571D14Mco5233149373661493736865Ratregion
67232D14Arb19215148385762283857837Ratregion
67234D14Arb21148205751882057712Ratregion
1630365D14Got131255149263463392634888Ratregion
1632095D14Got123293149023375590234048Ratregion
1628905D14Got135197148790240087902601Ratregion
1638917D14Got165300148855449888554798Ratregion
1641382D14Got168121149306112293061245Ratregion
1640481D14Got167200148854820788548407Ratregion
1635036D14Got124180149265088392651062Ratregion
5035731RH12683111149483739894837509Ratregion
5035861PMC24996P1147149166654891666686Ratregion
7206628Slc1a4999149453010794531106Ratregion
5036414Mor247149563297895633448Ratregion
5036879AU049495260149515210595152365Ratregion
5036953AU049735132149384062393840757Ratregion
5036993AU049852179149146059291460772Ratregion
5037067WI-13176112149444866194448773Ratregion
5025954RH130337181148682814286828323Ratregion
5026080RH130833210148638199386382203Ratregion
5031456AU048263167149137618791376354Ratregion
5034307UniSTS:226084138149530773295307870Ratregion
5034307UniSTS:226084138149530773295307870Ratregion
5032223AF07684594148369233683692430Ratregion
5032301AI84338996148399336483993460Ratregion
5029977BI285876220148755106387551283Ratregion
5030003BF388547221149330094493301165Ratregion
5033099RH137594196148628742986287625Ratregion
5033241RH138107143149099693090997073Ratregion
5028097X78987161149134414391344304Ratregion
5054029RH142989190148637665786376847Ratregion
5056945RH144671177149430326094303437Ratregion
5054281RH143134170148637876486378934Ratregion
5054353RH143175142149160928291609424Ratregion
5058550BE102015170149461700394617173Ratregion
5056143RH144208264148700468887004952Ratregion
5052373X95591184149167065291670836Ratregion
5052373X95591184149167065291670836Ratregion
5059734AI55680394149139712391397217Ratregion
5059786BE097865172148682711986827291Ratregion
5057768BF386159162149445049294450654Ratregion
5057816BI277192152149163735791638071Ratregion
5053717RH142810299148662615386626452Ratregion
5052661RH142192186149117567991175865Ratregion
5054245RH143114194148329262683292820Ratregion
5054719RH143386135149429754394297678Ratregion
5050966RH134361202149563147695632931Ratregion
5043562RH130096181148368875383688934Ratregion
5046168RH131597210149503362395033833Ratregion
5041688RH129001209149149238491492593Ratregion
5045306RH131102219149456212294562342Ratregion
5047550RH132392192149488114894881340Ratregion
5046186RH131608198149161028091610478Ratregion
5047614RH132429196149167095691671152Ratregion
5046604RH131849188148382909283829280Ratregion
5049198RH133342208149429699994297207Ratregion
5049344RH133427196149545641295456608Ratregion
5049722RH133644210149163954391639753Ratregion
5047240RH132214186149066617590666361Ratregion
5042144RH129265180149483794794838127Ratregion
7192181Rab1217149444474394444960Ratregion
5040360RH128238206149456584694566052Ratregion
5075622RH138701192149068689190687083Ratregion
5076320RH139107161149429833494298495Ratregion
5076330RH139113136149443935794439493Ratregion
5074650RH138139188149541647195416659Ratregion
5080590RH141668200149483395094834151Ratregion
5077412RH139741186149134610991346295Ratregion
5075108RH138403155149066546290665617Ratregion
5077764RH139945206148317567283175878Ratregion
5077434RH139754208148634247686342684Ratregion
5079850RH141239215149487154194871757Ratregion
5080208RH141447189149530890995309097Ratregion
5073852RH137676134149068819190688325Ratregion
5073974RH137746165149441770994417874Ratregion
5074302RH137938234148339273983392973Ratregion
5067884AU047478207148298744082987753Ratregion
5068424AU047153165148936775089367910Ratregion
5068498AU047109170149418309094183260Ratregion
5069985RH94401188148638186886382056Ratregion
5068756AU046951104148774269987742803Ratregion
5069388AU046532179148903762389037797Ratregion
5070502D11Ertd676e198149530797695308174Ratregion
5062182BF397527239148353452383534762Ratregion
5061860AW533906189149482369794823887Ratregion
5063924BE120256156148696728386967439Ratregion
5063978BE120360111149563052395630634Ratregion
5060738BF389057152149319170593191857Ratregion
5062860BI295229211149160861891608829Ratregion
5062962BE113504205149160647491606679Ratregion
5061628BF396931193149120005091200243Ratregion
5061668BF40239897149546195295462049Ratregion
5086145AI454148180149545475395454933Ratregion
5087392BQ194767162149529951495299676Ratregion
5089775AU049356155149581048295810637Ratregion
5089355AU049107113148946652089466637Ratregion
5089993AU049486133148255679282556927Ratregion
5088003Meis1154149315576793155921Ratregion
5088361AU048523130149206136292061492Ratregion
5090077AU049536186149237642592376613Ratregion
5082493BE119538181148358277283582953Ratregion
5082545BE119677141149499720994997350Ratregion
5083275BI27591393149446060294460695Ratregion
5083355AA81843790149429898894299078Ratregion
5086562AA891734191148317410383174294Ratregion
5081701BF408245147148637994686380092Ratregion
5085920AA996669111149134451491344625Ratregion
5083889AA893195121148376810583768226Ratregion
5503688MEIS1_7825747149315527193156018Ratregion
5503803UniSTS:471314379148205871282060338Ratregion
5503890SRCR23H933148889815688899089Ratregion
5504276D2S1567E89149563151695632217Ratregion
5504664PMC343796P1133149329148893291621Ratregion
5504805Hrmt1l2212148755203187552243Ratregion
5506290AFM324xh5861148682304686823907Ratregion
5506819G46230234148349301283493246Ratregion
5507267fb79b101407148291618282917589Ratregion
5500067UniSTS:236520158148637010586370263Ratregion
5502770PELI1165149530890795309072Ratregion
5502770PELI1165149530890795309072Ratregion
Position Markers

Flank 1: (D14Mit10)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21482,057,471 - 82,057,735 (+)MAPPER
Rnor_6.01487,458,772 - 87,459,035NCBI
Rnor_5.01481,093,112 - 81,093,375UniSTS
RGSC_v3.41487,960,277 - 87,960,541RGD
RGSC_v3.41487,960,278 - 87,960,541UniSTS
RGSC_v3.11487,979,422 - 87,979,686RGD
Celera1481,131,893 - 81,132,138UniSTS
RH 3.4 Map14602.4UniSTS
RH 3.4 Map14602.4RGD
RH 2.0 Map14719.4RGD
Cytogenetic Map14q21UniSTS
Flank 2: (D14Rat22)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21495,876,805 - 95,876,975 (+)MAPPER
Rnor_6.014106,641,587 - 106,641,756NCBI
Rnor_5.014106,704,868 - 106,705,037UniSTS
RGSC_v3.414102,509,228 - 102,509,397UniSTS
RGSC_v3.414102,509,227 - 102,509,397RGD
RGSC_v3.114102,528,439 - 102,528,608RGD
Celera1494,880,114 - 94,880,283UniSTS
RH 3.4 Map14758.0RGD
RH 3.4 Map14758.0UniSTS
RH 2.0 Map14823.7RGD
SHRSP x BN Map1466.2099RGD
FHH x ACI Map1475.96RGD
Cytogenetic Map14q22UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147341532392554092Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147341532392554092Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)147995092195876975Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)148205747195876975Rat
1582201Sffal2Serum free fatty acids level QTL 240.0002blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)149255388695876975Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general number of animals used: 19 parental GK, 20 parental F344, 37 F1 and 206 F2 rats 4889918
qtl_general lineage: F1 animals from both the reciprocal crosses were taken; 2 seperate F2 intercrosses were generated one from grandmaternal GK and grandpaternal F344 other from grandmaternal F344 and grandpaternal GK 4889918
qtl_general measurement method: at 4 months of age rats were given a fat enriched diet after 90 days they were sacrificed and left tibia was scanned in a CT unit (Somatom Sensation 64, Siemens Ag, Erlangen, Germany) 4889918
qtl_general software used: images were scanned Analyze version 5.0 4889918
qtl_general this region (72-84 cM) is determined only in F2 males 4889918