Bss88 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Bss88 (Bone structure and strength QTL 88) Rattus norvegicus

Symbol: Bss88
Name: Bone structure and strength QTL 88
RGD ID: 4889933
Trait: tibia size trait   (VT:0100001)    
Measurement Type: tibia total bone volume   (CMO:0001724)    
LOD Score: 3.8
P Value: Not Available
Variance: Not Available
Position No map positions available.
Cross Type: Not Available
Strains Crossed: GK/KyoSwe F344/DuCrlSwe 

Disease Annotations     Click to see Annotation Detail View
osteoporosis  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Measurement Method

Vertebrate Trait

Rat Strain
F344/DuCrlSwe  (IEA)
GK/KyoSwe  (IEA)


References - curated
# Reference Title Reference Citation
1. Genetic loci for bone architecture determined by three-dimensional CT in crosses with the diabetic GK rat. Lagerholm S, etal., Bone. 2010 Dec;47(6):1039-47. Epub 2010 Aug 10.


Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (D6Mgh11)
Rat AssemblyChrPosition (strand)Source
RH 3.4 Map6288.5UniSTS
RH 3.4 Map6288.5RGD
RH 2.0 Map6454.4RGD
Cytogenetic Map6 RGD
Flank 2: (D3Mit19)
Rat AssemblyChrPosition (strand)Source
RGSC_v3.1698,838,518 - 98,838,852RGD

Additional Information

RGD Curation Notes
Note Type Note Reference
null number of animals used: 19 parental GK, 20 parental F344, 37 F1 and 206 F2 rats 4889918
null lineage: F1 animals from both the reciprocal crosses were taken; 2 seperate F2 intercrosses were generated one from grandmaternal GK and grandpaternal F344 other from grandmaternal F344 and grandpaternal GK 4889918
null measurement method: at 4 months of age rats were given a fat enriched diet after 90 days they were sacrificed and left tibia was scanned in a CT unit (Somatom Sensation 64, Siemens Ag, Erlangen, Germany) 4889918
null software used: images were scanned Analyze version 5.0 4889918
null this region (31-50 cM) is determined only in F2 males 4889918