Eae32 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Eae32 (Experimental allergic encephalomyelitis QTL 32) Rattus norvegicus

Symbol: Eae32
Name: Experimental allergic encephalomyelitis QTL 32
RGD ID: 4889891
Previously known as: Eae23a
Trait: nervous system integrity trait   (VT:0010566)    
Measurement Type: experimental autoimmune encephalomyelitis severity score   (CMO:0001419)    
LOD Score: 4.8
P Value: 2.0E-4
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21727,027,949 - 36,146,731RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01727,690,959 - 38,110,914RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01729,605,177 - 39,973,813RGDRnor5.0
RGSC_v3.41733,277,173 - 42,659,723RGDRGSC3.4
Cross Type: Not Available
Strains Crossed: Kini:DA,PVG-G10 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Btn1a1 is a candidate Gene for Eae32

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. New loci regulating rat myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis. Becanovic K, etal., J Immunol 2003 Jan 15;170(2):1062-9.
2. Fine-mapping resolves Eae23 into two QTLs and implicates ZEB1 as a candidate gene regulating experimental neuroinflammation in rat. Stridh P, etal., PLoS One. 2010 Sep 15;5(9):e12716.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2070Agtr1aangiotensin II receptor, type 1a173417344634226892Rat
621572Foxq1forkhead box Q1173291274432915377Rat
621495F13a1coagulation factor XIII A1 chain172781572327992494Rat
621586Nrn1neuritin 1172812996928138898Rat
628838Uqcrfs1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1173397790833982478Rat
628836Wrnip1WRN helicase interacting protein 1173162141031641659Rat
619961Exoc2exocyst complex component 2173350628933698246Rat
620302Slc22a23solute carrier family 22, member 23173054410630709790Rat
1303320Nqo2N-ribosyldihydronicotinamide:quinone reductase 2173090948230938725Rat
735108Serpinb6aserpin family B member 6A173087142830989703Rat
1306203Serpinb1aserpin family B member 1A173159069531599102Rat
1309936Ly86lymphocyte antigen 86172741580727499695Rat
1307572Bphlbiphenyl hydrolase like173080093930837277Rat
1307784Prpf4bpre-mRNA processing factor 4B172998534330020285Rat
1311008GmdsGDP-mannose 4, 6-dehydratase173209531532621975Rat
1310452Serpinb6bserine (or cysteine) peptidase inhibitor, clade B, member 6b173145509231475460Rat
1560658Serpinb1bserine (or cysteine) peptidase inhibitor, clade B, member 1b173132013531329151Rat
1311307Pxdc1PX domain containing 1173027599830304971Rat
1309416Fars2phenylalanyl-tRNA synthetase 2, mitochondrial172831921528746217Rat
1309427Tubb2btubulin, beta 2B class IIb173074773430750781Rat
1310246Cdkal1CDK5 regulatory subunit associated protein 1-like 1173471868034769614Rat
1310246Cdkal1CDK5 regulatory subunit associated protein 1-like 1173485223835271276Rat
1308725Serpinb9dserine (or cysteine) peptidase inhibitor, clade B, member 9d173128643431294091Rat
1307537Tex56ptestis expressed 56172992985529966578Rat
1309488Sox4SRY-box transcription factor 4173566780935672515Rat
1310224Eci3enoyl-Coenzyme A delta isomerase 3172992196229943864Rat
1308930Ppp1r3gprotein phosphatase 1, regulatory subunit 3G172887495628878288Rat
1307146Dusp22dual specificity phosphatase 22173378098033831540Rat
1310228Rpp40ribonuclease P/MRP subunit p40172894773028956790Rat
1310158Ripk1receptor interacting serine/threonine kinase 1173083963930871824Rat
1308050Irf4interferon regulatory factor 4173372180033742570Rat
1564786RGD1564786similar to OTTMUSP00000000636173106870231085174Rat
1565561Mboat1membrane bound O-acyltransferase domain containing 1173433141334445088Rat
1563300RGD1563300similar to 60S ribosomal protein L29 (P23)173572225135722729Rat
1561689Erp29-ps1endoplasmic reticulum protein 29, pseudogene 1172962366029628679Rat
1562844RGD1562844similar to serine (or cysteine) proteinase inhibitor, clade B, member 9173137819031386218Rat
1549745Cdylchromodomain Y-like172898200929204345Rat
1549730Serpinb9serpin family B member 9173142011831443237Rat
1561310RGD1561310similar to ribosomal protein L37173470562034705949Rat
1359427Eci2enoyl-CoA delta isomerase 2172985088429886781Rat
1585035Hus1bHUS1 checkpoint clamp component B173353411333534943Rat
1566214Fam217afamily with sequence similarity 217, member A172997502529981455Rat
1563458Fam50bfamily with sequence similarity 50, member B173017443130193627Rat
1564781Eno1-ps13enolase 1, pseudogene 13172802393328025229Rat
1563601RGD1563601similar to Tpi1 protein172710143127102823Rat
1561697Serpinb6eserine (or cysteine) peptidase inhibitor, clade B, member 6e173117798531187261Rat
1561600E2f3E2F transcription factor 3173460175634679139Rat
1565323RGD1565323similar to OTTMUSP00000000621173166171331678816Rat
1589955Psmg4proteasome assembly chaperone 4173071068230718035Rat
1588452Tubb2atubulin, beta 2A class IIa173079684230800713Rat
1589717Foxf2forkhead box F2173283573032842555Rat
1589718Foxc1forkhead box C1173263137932635361Rat
1589719Hmgb1-ps2high mobility group box 1, pseudogene 2173004087930042758Rat
1589720Rps7-ps16ribosomal protein S7, pseudogene 16172926770129268243Rat
2320008LOC100364958hypothetical LOC100364958173078574030791208Rat
6494757Mylk4myosin light chain kinase family, member 4173166902831747250Rat
6490193Rps9-ps1ribosomal protein S9, pseudogene 1173347005933470620Rat
6501716Ppp1r14b-ps1protein phosphatase 1, regulatory (inhibitor) subunit 14B, pseudogene173552639435527121Rat
6500583LOC100909970uncharacterized LOC100909970172717681727186106Rat
6497764LOC100910628uncharacterized LOC100910628172734624427350547Rat
6501250LOC100909866uncharacterized LOC100909866173556487135595211Rat
7496066LOC102548372uncharacterized LOC102548372173559614135666254Rat
7530502Nono-ps6non-POU domain containing, octamer-binding, pseudogene 6173439690534398376Rat
7653735LOC102550566uncharacterized LOC102550566172887776428888892Rat
7659104Gyg1-ps1glycogenin 1, pseudogene 1173396983933972043Rat
7546074LOC102548193uncharacterized LOC102548193173535019135355917Rat
7560629LOC102551220uncharacterized LOC102551220173074554230747619Rat
7582386LOC102555109uncharacterized LOC102555109173154067631544857Rat
7584662LOC102549751uncharacterized LOC102549751172730850727321615Rat
7707333Rps11-ps4ribosomal protein S11, pseudogene 4173355257233553085Rat
7723369LOC102554685uncharacterized LOC102554685173095400130970983Rat
7672286Lyrm4LYR motif containing 4172874644228861849Rat
9173217LOC103694077uncharacterized LOC103694077173322894933251259Rat
9327804Rps27a-ps20ribosomal protein S27a, pseudogene 20173171087731711529Rat
9393815LOC103694081uncharacterized LOC103694081173466044134663290Rat
11471267LOC108348556uncharacterized LOC108348556173393810033941366Rat
11429054LOC108348552uncharacterized LOC108348552173143107431436254Rat
11425070LOC108348554uncharacterized LOC108348554173164303231654258Rat
11408958LOC108348555uncharacterized LOC108348555173176936731775965Rat
11499165LOC108348548uncharacterized LOC108348548172732163427337157Rat
14398591Mir6319-1microRNA mir-6319-1173358671533586841Rat
41110843LOC120098004small nucleolar RNA SNORA17173312192033122044Rat
41166840LOC120097742uncharacterized LOC120097742173263615932644435Rat
41355240LOC120097779uncharacterized LOC120097779173284257832848184Rat
41325100LOC120097753uncharacterized LOC120097753173072935630731649Rat
41115616LOC120097899uncharacterized LOC120097899172724529327253746Rat
41209243LOC120097905uncharacterized LOC120097905173577622635777984Rat
41155498Atp5mf-ps4ATP synthase membrane subunit f, pseudogene 4173375613233764208Rat
41289478LOC120097796uncharacterized LOC120097796172734273527349500Rat
41372163Hdac1-ps16Histone deacetylase 1, pseudogene 16172884967128850978Rat
41292709LOC120097861uncharacterized LOC120097861172912686329136858Rat
41197145LOC120098016U2 spliceosomal RNA173443164734431825Rat
41228821LOC120097975small nucleolar RNA SNORA67173529920635299336Rat
41164048LOC120097838uncharacterized LOC120097838173358677133620238Rat
41274170LOC120097945uncharacterized LOC120097945173439871834401450Rat
41136285LOC120098022U2 spliceosomal RNA173158542531585513Rat
40949153LOC120097754uncharacterized LOC120097754173047881530539097Rat
41341903Phgdh-ps3phosphoglycerate dehydrogenase, pseudogene 3172749288027494388Rat
40976926LOC120097828uncharacterized LOC120097828172804854328051080Rat
41015448LOC120098052U1 spliceosomal RNA173529101235291164Rat
41001744LOC120097839uncharacterized LOC120097839173356528133567359Rat
41006362LOC120097731uncharacterized LOC120097731173520283535220004Rat
40988637LOC120098041U1 spliceosomal RNA172733777527337940Rat
41313473LOC120093069threonylcarbamoyladenosine tRNA methylthiotransferase-like173485223835271276Rat
41025517LOC120097993small nucleolar RNA SNORA17172956217729562309Rat
41223489LOC120097730uncharacterized LOC120097730172813469328137678Rat
41300457LOC120097733uncharacterized LOC120097733173512906335142313Rat
41034711LOC120097996small nucleolar RNA SNORA17172820150128201626Rat
41035220LOC120098017U2 spliceosomal RNA173282822332828285Rat
41226905LOC120098054U6 spliceosomal RNA173168715831687268Rat
41067460LOC120098014U2 spliceosomal RNA173474368234743788Rat
41022734LOC120097830uncharacterized LOC120097830172720362027213382Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10119D17Arb4198173422548134225727Ratregion
10119D17Arb4198173422548134225872Ratregion
10119D17Arb4198173422556634225727Ratregion
33882D17Mit2125173199078431990913Ratregion
36011D17Rat17168173583708535837242Ratregion
36225D17Rat15136173136839131368534Ratregion
36269D17Rat14141172743957027439721Ratregion
34827D17Rat12158172702794927028127Ratregion
35637D17Rat13160172783515427835317Ratregion
35697D17Rat16153173455084334551001Ratregion
38590D17Rat77217173319889733199113Ratregion
39346D17Rat67148172908699329087143Ratregion
43086D17Rat163136172944593829446060Ratregion
43088D17Rat162200173164329431643498Ratregion
43089D17Rat181170173189601031896169Ratregion
42415D17Rat178203173260893032609135Ratregion
42416D17Rat179200173596462835964824Ratregion
41652D17Rat155144173213163632131780Ratregion
45467D17Got51292173607302736073321Ratregion
60139D17Got114108173074524330745351Ratregion
45448D17Got34137172718958227189719Ratregion
45449D17Got42245172715841227158657Ratregion
45450D17Wox3100172738980227389946Ratregion
45453D17Got3894172863483728634931Ratregion
45454D17Got39152172914629929146451Ratregion
45455D17Got43124173146318331463308Ratregion
45457D17Got37111172926131229261423Ratregion
45458D17Got41137172792160027921737Ratregion
45459D17Got44234173178890631789137Ratregion
45461D17Got116152173282175632821908Ratregion
45462D17Got48288173513821835138503Ratregion
45463D17Got50212173574103435741246Ratregion
45464D17Got49203173614652836146731Ratregion
45465D17Got47175173568395135684123Ratregion
66514D17Mco2272172979905629799326Ratregion
66518D17Mco6206173423066934230882Ratregion
67276D17Arb9289173349259533492884Ratregion
1556753D17Chm55393173446144534461838Ratregion
1630424D17Wox26221173367748733677708Ratregion
1631751D17Wox34295173422727634227609Ratregion
1627009D17Mco9262173422703634227298Ratregion
1627582D17Got228139173265646032656599Ratregion
1640215D17Got233244172713682227137065Ratregion
1632516D17Got219103173053127830531381Ratregion
7192472Agtr1a691173417588634176577Ratregion
5035751STS-N25875140173263143532631575Ratregion
5036015PMC85656P1110173460170734601817Ratregion
5036175D13Cwr18268173253234032532608Ratregion
5036177D13Cwr27109173268646132686570Ratregion
5036569AU048462155173579643935796595Ratregion
5039068RH127494204173142023731420441Ratregion
5036775AU049163261173552974735530008Ratregion
5037113D6S1932180172998855629988736Ratregion
7206174Tubb2b188173074778030748776Ratregion
5028893RH142724227173602537836025605Ratregion
5031578AU047860140173074839430748534Ratregion
5026280RH131606190173378102033781210Ratregion
5026290RH131644196173511499835115194Ratregion
5029057RH143354103173397796733978070Ratregion
5034542BI274644193173137844431378637Ratregion
5026676RH133113198173283589332836091Ratregion
5034716BE100150153173159454331594696Ratregion
5029512AI555874216173602547336025689Ratregion
5026948RH134148181173398296633983150Ratregion
5029691BG376613181172986997229870153Ratregion
5029697AI05868790173136220631362296Ratregion
5029787BF387292150173248082732480977Ratregion
5029901BE097633152173558664135586792Ratregion
5027781RH94717277173417492734175204Ratregion
5025482RH128491211173155523931555450Ratregion
5028159D13Mit82117173553059335530710Ratregion
5025624RH129034150173104513531045281Ratregion
5053811RH142864244173137828431378528Ratregion
5053939RH142938225173000872030008945Ratregion
5054507RH143264234173291333132913565Ratregion
5050772RH134249151173030472030304871Ratregion
5054817RH143442138172876406828764206Ratregion
5054865RH143469204173255141732551621Ratregion
5051030RH134397197172988642329886620Ratregion
5045850RH131415193173041768730417881Ratregion
5041736RH129029193173174705231747245Ratregion
5046296RH131671199173027999230280191Ratregion
5046380RH131719214173353473833534952Ratregion
5044518RH130649183173417498034175163Ratregion
5047788RH132528199173159872731598926Ratregion
5049308RH133406187173162162031621807Ratregion
5047884RH132584213173129417931294392Ratregion
5049378RH133446220172887517828875399Ratregion
5048274RH132808193173391045233910647Ratregion
5042790RH129647196173322311233224009Ratregion
5040378RH128249184173367816333678347Ratregion
5039880RH127960220173398205133982271Ratregion
5040674RH128418199173433162134331820Ratregion
5043598RH130117196173094938930949583Ratregion
5043162RH129867190173098945830989648Ratregion
5074154RH137853242173566417035664412Ratregion
5074798RH138224234173054655730546791Ratregion
5079584RH141084183172994253329943712Ratregion
5079624RH141109186173075007630750574Ratregion
5079624RH141109186173080006930800523Ratregion
5079666RH141133212173145803331458245Ratregion
5070746RH134680199173083978130839980Ratregion
5080338RH141522213173084151730841730Ratregion
5070582RH134585188173567056135670749Ratregion
5073284RH137347189173070893830709127Ratregion
5071906RH135353216173075122430751440Ratregion
5063472BF398903155173284631632846471Ratregion
5068830AU046900191172709551227095703Ratregion
5069042AU046761143172749004627490191Ratregion
5069608AU046385252173607301336073262Ratregion
5065776BE109841156172886310628863262Ratregion
5066382AU048390195173001372030013915Ratregion
5064922BF399928153173080556530805718Ratregion
5066434AU048359283172912517529125458Ratregion
5061646BE105728164172887592028876084Ratregion
5084192AI012624200173145515731455357Ratregion
5087916Hfh1103173291421232914315Ratregion
5087920Hfh1l165173291454532914710Ratregion
5088112Sox4210173566962435669834Ratregion
5088945AU048862117172944597229446089Ratregion
5088134Tubb2195173080042430800619Ratregion
5088273AU048470194173169034531690537Ratregion
5089305AU049076253173450211434502369Ratregion
5083561BI276174205173142070531420910Ratregion
5088323AU048501173173045036430450537Ratregion
5088445AU048573236172996464129964877Ratregion
5087632PMC85656P2175173460110034601275Ratregion
5085349BQ210005208172814648828146696Ratregion
5082565BE119712166172887167528871841Ratregion
5080810RH141796194173079742830797622Ratregion
5083005BF390609164173080565930805823Ratregion
5086173BM386176176172707861527078791Ratregion
5086640BM387323189172731033927310528Ratregion
5503910UniSTS:256385641173417593634176577Ratregion
5507636Rnasep1342172895511928956732Ratregion
5505782UniSTS:493122831173353411233534943Ratregion
5505986UniSTS:49674591173566961235669703Ratregion
5501572RH79983202173567138435671586Ratregion
5501748MARC_10647-10648:1000474126:1491173567195835672449Ratregion
5502072MARC_26445-26446:1030655521:1133173074912330749576Ratregion
5502072MARC_26445-26446:1030655521:1133173079868530799569Ratregion
5505279Serpinb6c60173097800030978060Ratregion
Position Markers

Flank 1: (D17Rat12)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21727,027,949 - 27,028,127 (+)MAPPER
Rnor_6.01727,690,959 - 27,691,136NCBI
Rnor_5.01729,605,177 - 29,605,354UniSTS
RGSC_v3.41733,277,173 - 33,277,509RGD
RGSC_v3.41733,277,332 - 33,277,509UniSTS
RGSC_v3.11733,280,173 - 33,280,350RGD
Celera1726,659,615 - 26,659,792UniSTS
RH 3.4 Map17341.4UniSTS
RH 3.4 Map17341.4RGD
RH 2.0 Map17254.9RGD
SHRSP x BN Map1721.7999RGD
FHH x ACI Map1727.8099RGD
Peak: (D17Got45)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21740,200,266 - 40,200,450 (+)MAPPER
Rnor_6.01742,200,997 - 42,201,180NCBI
Rnor_5.01744,068,796 - 44,068,979UniSTS
RGSC_v3.41747,261,859 - 47,262,043RGD
RGSC_v3.41747,261,860 - 47,262,043UniSTS
RGSC_v3.11747,264,700 - 47,264,884RGD
Celera1739,837,565 - 39,837,748UniSTS
RH 2.0 Map17314.3RGD
Cytogenetic Map17p11UniSTS
Flank 2: (D17Got49)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21736,146,528 - 36,146,731 (+)MAPPER
Rnor_6.01738,110,712 - 38,110,914NCBI
Rnor_5.01739,973,611 - 39,973,813UniSTS
RGSC_v3.41742,659,520 - 42,659,722RGD
RGSC_v3.41742,659,521 - 42,659,723UniSTS
RGSC_v3.11742,662,361 - 42,662,563RGD
Celera1735,654,004 - 35,654,206UniSTS
RH 3.4 Map17417.4UniSTS
RH 3.4 Map17417.4RGD
RH 2.0 Map17305.1RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17435448727028127Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
4889891Eae32Experimental allergic encephalomyelitis QTL 324.80.0002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)172702794936146731Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
2313854Bp343Blood pressure QTL 3433.9life span trait (VT:0005372)age at time of death (CMO:0001193)173199078450909196Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general inducing agent: myelin oligodendrocyte glycoprotein aa1-125 4889889
qtl_general measurement method: 8-11 weeks old rats were induced with 20 microgram of MOG per rat, animals were monitored and weighed daily beginning from day 9-35 p.i. until sacrificed 31-38 days, for changes in weight and for clinical signs of paresis/paralysis which were scored on a scale from 0-5 4889889
qtl_general number of animals used: 772 10th generation of advanced intercross lines 4889889
qtl_general spans 21 Mb 4889889
qtl_general this region and Eae33 were determined as suggestive QTLs for maximum Eae score and incidence 629629