GWAS1060224_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1060224_H (adrenomedullin measurement QTL GWAS1060224 (human)) Homo sapiens

Symbol: GWAS1060224_H
Name: adrenomedullin measurement QTL GWAS1060224 (human)
RGD ID: 407411248
Trait: kidney adrenomedullin amount   (VT:0010754)    
Measurement Type: kidney adrenomedullin level   (CMO:0002916)    
LOD Score: Not Available
P Value: 1.0E-13
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh383186,735,641 - 186,735,642RGD_MAPPER_PIPELINEGRCh38
GRCh373186,453,430 - 186,453,439RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1060224_HHumankidney adrenomedullin level  IAGPrs138610068405850206 GWAS_CATALOGPMID:29875488

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1060224_HHumankidney adrenomedullin amount  IAGPrs138610068405850206 GWAS_CATALOGPMID:29875488

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1060224_HHumanadrenomedullin measurement  IAGPrs138610068405850206 GWAS_CATALOGPMID:29875488
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1603713KNG1kininogen 13186717359186744410Human

Position Markers

Peak: (rs138610068)
Human AssemblyChrPosition (strand)Source
GRCh383186,735,641 - 186,735,642RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407399385GWAS1048361_Hkininogen-1 measurement QTL GWAS1048361 (human)6e-59kininogen-1 measurement3186735641186735642Human
407411248GWAS1060224_Hadrenomedullin measurement QTL GWAS1060224 (human)1e-13kidney adrenomedullin amount (VT:0010754)kidney adrenomedullin level (CMO:0002916)3186735641186735642Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1048361_H GCST90137890 Kininogen-1 levels 1,852 African American or Afro-Caribbean individuals ? NR 6E-59 58.222 rs138610068 1.46 kininogen-1 measurement (EFO:0008198)
 PMID:34814699
GWAS1060224_H GCST90240213 Adrenomedullin levels (ADM.14115.34.3) 3,301 European ancestry individuals G 0.12 1E-13 13 rs138610068 0.28 adrenomedullin measurement (EFO:0010909)
 PMID:29875488
Database Acc Id Source(s)
GWAS Catalog GCST90240213 GWAS Catalog

RGD Curation Notes
Note Type Note Reference