Eae25 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Eae25 (Experimental allergic encephalomyelitis QTL 25) Rattus norvegicus

Symbol: Eae25
Name: Experimental allergic encephalomyelitis QTL 25
RGD ID: 2317586
Trait: nervous system integrity trait   (VT:0010566)    
Measurement Type: experimental autoimmune encephalomyelitis severity score   (CMO:0001419)    
LOD Score: 9.300000190734863
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,882,817 - 83,007,655RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0479,559,380 - 84,053,053RGD_MAPPER_PIPELINERnor6.0
Rnor_5.04144,235,277 - 148,715,224RGDRnor5.0
RGSC_v3.4478,039,509 - 82,266,081RGDRGSC3.4
Cross Type: Not Available
Strains Crossed: DA/ZtmKini PVG.1AV1/Kini 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Multiple loci comprising immune-related genes regulate experimental neuroinflammation. Marta M, etal., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13.
2. Data registered by Dr. Olsson Personal communication between Dr. Olsson and the RGD curators.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2814Hoxa4homeo box A448128967781291685Rat
3197Npyneuropeptide Y47888129478888495Rat
2451Cycscytochrome c, somatic47965189479653994Rat
620159Skap2src kinase associated phosphoprotein 248094883281100900Rat
708579Tax1bp1Tax1 binding protein 148182199181877906Rat
620609Hoxa5homeo box A548130234181306234Rat
708399Hibadh3-hydroxyisobutyrate dehydrogenase48164918081747244Rat
61815Npvfneuropeptide VF precursor47971252079716236Rat
1307730Nfe2l3NFE2 like bZIP transcription factor 348050675680534629Rat
727871Gsdmegasdermin E47925879979321129Rat
1310403Hnrnpa2b1heterogeneous nuclear ribonucleoprotein A2/B148053465980545297Rat
1310827TrilTLR4 interactor with leucine-rich repeats48292232782927172Rat
1310001Hoxa9homeobox A948132323581329344Rat
1305782Snx10sorting nexin 1048061264880677005Rat
1563788LOC500124similar to RIKEN cDNA 4921507P0747966337579688282Rat
1564605Hoxa11homeobox A1148134252781346189Rat
1566107Creb5cAMP responsive element binding protein 548239309182794320Rat
1549705Cbx3chromobox 348054545080559284Rat
1311833Pals2protein associated with LIN7 2, MAGUK p55 family member47917348879257542Rat
1587253Hoxa7homeobox A748131573081317629Rat
1563609Cpvlcarboxypeptidase, vitellogenic-like48298142183091730Rat
1561431Hoxa3homeobox A348126924381313218Rat
1562483Hoxa13homeo box A1348135895681361091Rat
1565415RGD1565415similar to ribosomal protein L27a47963353979634311Rat
1561341RGD1561341similar to Translocase of outer mitochondrial membrane 20 homolog48060334280603836Rat
1564419Hoxa11-asHOXA11 antisense RNA48134641681350190Rat
1564287Osbpl3oxysterol binding protein-like 347934658379523523Rat
1589007Jazf1JAZF zinc finger 148187950182183241Rat
1590236Hoxa6homeobox A648130491881313184Rat
1592878Cux1-ps1cut-like homeobox 1, pseudogene 148026982180271956Rat
1593814Aurka-ps3aurora kinase A, pseudogene 347981143179812875Rat
2314882Mir196bmicroRNA 196b48133048781330571Rat
2319193Rpl36a-ps13ribosomal protein L36A, pseudogene 1347985997579860338Rat
2319409Rpl30-ps9ribosomal protein L30, pseudogene 947957764879578130Rat
6491746LOC100911668homeobox protein Hox-A10-like48133159181341241Rat
7508808LOC102546824uncharacterized LOC10254682447999538680054736Rat
7624339LOC102546410uncharacterized LOC10254641047965417279689329Rat
7657543LOC102549423uncharacterized LOC10254942348041680780427041Rat
7570592LOC102550087uncharacterized LOC10255008748110093781144318Rat
7571074LOC102555694uncharacterized LOC10255569447903911779041508Rat
7620814LOC102546856uncharacterized LOC10254685648127531381293064Rat
7551122Srsf7-ps5serine and arginine rich splicing factor 7, pseudogene 548214009382142214Rat
7716070Hotairm1Hoxa transcript antisense RNA, myeloid-specific 148125879381262291Rat
9685082Mir148amicroRNA 148a48033376280333858Rat
10398773Hoxaas3Hoxa cluster antisense RNA 348130125481313958Rat
11414885Hoxa1homeobox A148125581481258504Rat
11420575LOC10835086060S ribosomal protein L31 pseudogene48119187681192258Rat
11401676LOC108350707uncharacterized LOC10835070747979076779795915Rat
11492396LOC108350711uncharacterized LOC10835071148215375582165281Rat
41113909Ndufb4-ps7NADH:ubiquinone oxidoreductase subunit B4, pseudogene 748147423881474752Rat
41173484Rpl21-ps7ribosomal protein L21, pseudogene 748117475881175534Rat
41093189LOC120102273uncharacterized LOC12010227348082463680828739Rat
41150076LOC120102279uncharacterized LOC12010227948170440281727173Rat
41099928LOC120102275uncharacterized LOC12010227548119303681208800Rat
41399556LOC120102270uncharacterized LOC12010227048047185780479206Rat
41162112LOC120102268uncharacterized LOC12010226847952343879529558Rat
41106900LOC120102272uncharacterized LOC12010227248063104480644379Rat
41294070Ckmt1-ps1creatine kinase, mitochondrial 1, pseudogene 148228467082319694Rat
41108658LOC120102517uncharacterized LOC12010251748089814280924068Rat
41083837LOC120102163uncharacterized LOC12010216348018866680191301Rat
40973112LOC120102280uncharacterized LOC12010228048225601382264460Rat
40974159LOC120102277uncharacterized LOC12010227748157824081580768Rat
40941309LOC120102276uncharacterized LOC12010227648128008781281256Rat
41074832LOC120102667small nucleolar RNA SNORA1748298003982980170Rat
41025668LOC120102271MICOS complex subunit MIC13-like48062378580625489Rat
41028316LOC120102281uncharacterized LOC12010228148232552182347057Rat
41052635LOC120102269uncharacterized LOC12010226948011040280114314Rat
41298329LOC120102516basic proline-rich protein-like47916687779179773Rat
41061164LOC120102676small nucleolar RNA SNORA1747962350279623632Rat
41226461LOC120102278uncharacterized LOC12010227848161340681619082Rat
41301986LOC120102651small nucleolar RNA SNORA4848229639982296539Rat
41305549LOC120102274uncharacterized LOC12010227448082881280830571Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
11009D4Wox2113847888281778882954Ratregion
11010D4Hri147888281778882945Ratregion
11012D4Wox2216247888598978886137Ratregion
11013D4Arb726447888586778886157Ratregion
11014D4Mit710347888589078886189Ratregion
11015D4Mit2412847888281578882945Ratregion
35190D4Rat22714347973494979735095Ratregion
36870D4Rat3316048100612481006281Ratregion
37646D4Rat10812248284404882844186Ratregion
37906D4Rat12720147934020379340408Ratregion
38656D4Rat12812247998687379987019Ratregion
39180D4Rat13820048244335582443549Ratregion
39530D4Rat21523048257601882576250Ratregion
42172D4Arb3513047888281578882964Ratregion
42705D4Rat26524248300743383007655Ratregion
42706D4Rat28923148300745983007658Ratregion
40932D4Rat16623647959552579595727Ratregion
43816D4Got6420648165562081655823Ratregion
43818D4Got6214447980177779801923Ratregion
43819D4Got6617748280301482803190Ratregion
60431D4Got15829648206668382066979Ratregion
60447D4Got6114748114230281142449Ratregion
66669D4Mco221847978869079788919Ratregion
1631514D4Got21118848044537780445563Ratregion
1626708D4Kini115648249035982490515Ratregion
1626710D4Kini217748188525381885430Ratregion
1628038D4Cebr511048070233280702442Ratregion
1629518DXGot14229948107104881071080Ratregion
1641131D4Got21219448150411081504306Ratregion
7193115Hoxa1320148136020281360403Ratregion
7193118Hoxa13118348135937081360553Ratregion
7192163Hoxa518248130192581302107Ratregion
7192164Hoxa729948131716781317466Ratregion
7192162Hoxa514848130192081302068Ratregion
7206304Hoxa18148125836781258448Ratregion
7206308Hoxa117448134599081346064Ratregion
7206310Hoxa27548126476081264835Ratregion
7206312Hoxa1381948135936481360183Ratregion
7206314Hoxa38948127267581272764Ratregion
7206316Hoxa47248129042981290501Ratregion
7206318Hoxa58548130424581304330Ratregion
7206320Hoxa66848130867781308745Ratregion
7206322Hoxa77748131743081317507Ratregion
7206338Hoxa96748132615581326222Ratregion
5035807PMC195978P134347965410579654448Ratregion
7206658Hoxa1384048135936181360201Ratregion
5036344Hoxa1320348135929181359494Ratregion
5036346Hoxa722348131581281316035Ratregion
5036947AU04971417948152358381523762Ratregion
5028697D7S277434148133247881332819Ratregion
5031458AU04825624047891206378912303Ratregion
5030187BF38954620148275459982754800Ratregion
5027693RH6563113948183924981839388Ratregion
5033047RH13739420447935038579350589Ratregion
5025338RH12793419748127833881278535Ratregion
5028067U2037119348134351681343709Ratregion
5028171D14Mit29047888589078886189Ratregion
5033553RH13924512248054505580545177Ratregion
5028273D6Mit240.111348014333980143452Ratregion
5028312RH12216129848282887782829175Ratregion
5028338SGC3178910048187741781877517Ratregion
5030899BE10800719848186513781865335Ratregion
5030921BE10814414047969576979695909Ratregion
5052037RH9480425547888616678886421Ratregion
5055027RH14356314648292291682923062Ratregion
5051200RH13449718548187748281877667Ratregion
5051759RH946429948125685581256954Ratregion
5059448AW53087516048002279080022950Ratregion
5057614BI2832829948031398480314083Ratregion
5058746BF38701915348203294482033097Ratregion
5056607RH14447617347968912179689294Ratregion
5057003Hoxa515148130266281302813Ratregion
5055437RH14380015548278973882789893Ratregion
5059726BF39426522448277615782776381Ratregion
5059768BI29194115248135664781356799Ratregion
5055651RH14392426448239418482394448Ratregion
5052385D14Mit29.111047888583378885943Ratregion
5050378RH13402218248292238082922562Ratregion
5051234RH13451619848095076880950966Ratregion
5041798RH12906518048187956181879741Ratregion
5045022RH13093820048239445782394657Ratregion
5048944RH13319618548279291182793096Ratregion
5047868RH13257520248126295981263161Ratregion
5049254RH13337420248128985581290057Ratregion
5049632RH13359221547917458779174802Ratregion
5039374RH12766921947925727779257496Ratregion
7192215Hoxa9140048132442981325829Ratregion
5042960RH12974721148094895980949169Ratregion
5074010RH13776713948279402782794166Ratregion
5075144RH13842413747925345379253590Ratregion
5071112RH13489319948292349582923694Ratregion
5073324RH13737015148158842081588571Ratregion
5071690RH13522818648131581281315998Ratregion
5071708RH13523820748134011381340320Ratregion
5066678AU04821517348235615282356325Ratregion
5070277RH9457410047888836178888460Ratregion
5069150AU04669128148100609381006376Ratregion
5069240AU04662813848188528181885420Ratregion
5065340AA96372018748053683380537020Ratregion
5065340AA96372018748053683380537020Ratregion
5062496BF39799613047942872479428854Ratregion
5063798AW53521017548131069081310865Ratregion
5062822AW52837318448054662180546806Ratregion
5061218BI29344316947938233879382507Ratregion
5064638BF39949016747967895079679117Ratregion
5064662BF39953525047925882579259075Ratregion
5087769D11Bir939648015197380152369Ratregion
5087930Hoxa215148126336981263520Ratregion
5087932UniSTS:14336617048126199481262164Ratregion
5087928UniSTS:14336021648125816781258383Ratregion
5089153AU04898610748065998480660026Ratregion
5084688AI17063010548129270381292808Ratregion
5082101BF40953915848279621482796372Ratregion
5084596AI17043313948094637480946513Ratregion
5082921BF39041715048185780181857955Ratregion
5086311BM38703420348172209181722294Ratregion
5083885AA89314120748133269081332897Ratregion
5507489ECD0549673748134570981346446Ratregion
5507674Hoxa10153748133299381334530Ratregion
5503746Hoxa956548132386381324428Ratregion
5506113UniSTS:4983868548134348681343571Ratregion
5506322UniSTS:47475131148134286381343174Ratregion
5506642ECD0064489648126362681264522Ratregion
5506632ECD0030890848133201581332923Ratregion
5507377REN10070423148134545181345682Ratregion
5499519stSG609304109348125449681255589Ratregion
5499521stSG609316103248126604681267080Ratregion
5499567AI3247018448126363581263719Ratregion
5499601MARC_1211-1212:991931105:121648053871780539093Ratregion
5499523stSG60934921948130201581302234Ratregion
5499525stSG609369125648132439781325653Ratregion
5499639MARC_6217-6218:992007117:123548130204981302284Ratregion
5500747UniSTS:5764934548130219581302539Ratregion
5503704UniSTS:46753645948127230681272765Ratregion
5503708UniSTS:46753733548130840681308741Ratregion
5501307ECD1314550748141629981416807Ratregion
5501311ECD1433250348127735781277860Ratregion
5501323ECD1607740348129079881291201Ratregion
5501796MARC_12745-12746:1030738152:139848126341781263815Ratregion
5506638ECD0041690248133298381333885Ratregion
5507333REN9980723248118258881182820Ratregion
5507335REN10030227248125700381257275Ratregion
5507337REN10033825548126457881264833Ratregion
5507339REN10033924048126481181265051Ratregion
5507341REN10036325148127014581270396Ratregion
5507343REN10037526748127279781273064Ratregion
5507345REN10043624948128548581285734Ratregion
5507347REN10044427748128749281287769Ratregion
5507349REN10046423448129163681291870Ratregion
5507351REN10050725248130109481301346Ratregion
5507353REN10051127548130193781302212Ratregion
5507355REN10051225848130219781302454Ratregion
5507357REN10052224748130431781304564Ratregion
5507359REN10056323548131340581313640Ratregion
5507361REN10058022548131742681317651Ratregion
5507363REN10053326148130667081306931Ratregion
5507365REN10061924748132595381326200Ratregion
5507367REN10062025648132618081326436Ratregion
5507369REN10065822748133519281335419Ratregion
5507371REN10064223348133133781331570Ratregion
5507373REN10065925448133540081335654Ratregion
5507375REN10070322648134524881345474Ratregion
5507379REN10077122748136033981360566Ratregion
5507381REN10070626048134588781346147Ratregion
5507383REN10098922548142445881424683Ratregion
5507385REN10142623548153620081536435Ratregion
Position Markers

Flank 1: (D4Wox21)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2478,882,817 - 78,882,954 (+)MAPPER
Rnor_6.0479,575,534 - 79,575,667NCBI
Rnor_6.0479,559,380 - 79,559,514NCBI
Rnor_5.04144,249,326 - 144,249,459UniSTS
Rnor_5.04144,235,277 - 144,235,411UniSTS
RGSC_v3.4478,039,509 - 78,039,646RGD
RGSC_v3.4478,039,510 - 78,039,646UniSTS
RGSC_v3.1478,315,639 - 78,315,776RGD
Celera473,796,672 - 73,796,816UniSTS
RH 3.4 Map4504.2UniSTS
RH 3.4 Map4504.2RGD
RH 2.0 Map4547.5RGD
Cytogenetic Map4q24UniSTS
Peak: (D4Got64)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2481,655,620 - 81,655,823 (+)MAPPER
Rnor_6.0482,610,808 - 82,611,010NCBI
Rnor_5.04147,277,172 - 147,277,374UniSTS
RGSC_v3.4480,856,738 - 80,856,941RGD
RGSC_v3.4480,856,739 - 80,856,941UniSTS
RGSC_v3.1481,141,361 - 81,141,563RGD
Celera476,538,213 - 76,538,415UniSTS
RH 3.4 Map4516.1UniSTS
RH 3.4 Map4516.1RGD
RH 2.0 Map4555.7RGD
Cytogenetic Map4q24UniSTS
Flank 2: (D4Rat265)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2483,007,433 - 83,007,655 (+)MAPPER
Rnor_6.0484,052,832 - 84,053,053NCBI
Rnor_5.04148,715,003 - 148,715,224UniSTS
RGSC_v3.4482,265,859 - 82,266,081RGD
RGSC_v3.4482,265,860 - 82,266,081UniSTS
RGSC_v3.1482,550,481 - 82,550,703RGD
Celera477,885,488 - 77,885,709UniSTS
SHRSP x BN Map441.93RGD
SHRSP x BN Map441.93UniSTS
Cytogenetic Map4q24UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42949419581006281Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43443048482490359Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)45664777678882945Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)45664777678882945Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)45664777678882945Rat
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)45664777678882945Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711443291360801Rat
634311Sach7Saccharin preference QTL 7taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)457114432102114432Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)45843213392991462Rat
631671Iddm11Insulin dependent diabetes mellitus QTL 113.60.0012blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)45863587778886137Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)460220938105220938Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)460220938105220938Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658103194791Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46293326987483707Rat
8552807Vie4Viral induced encephalitis QTL 47.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)46293350882490359Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in mean arterial blood pressure (CMO:0002035)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in systolic blood pressure (CMO:0000747)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in pulse pressure (CMO:0001882)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)46588210796130297Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)470808386115808386Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)470808386115808386Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)473630210118630210Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)473630210118630210Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
2317586Eae25Experimental allergic encephalomyelitis QTL 259.300000190734863nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)47888281783007655Rat
2317586Eae25Experimental allergic encephalomyelitis QTL 259.300000190734863nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)47888281783007655Rat
2317586Eae25Experimental allergic encephalomyelitis QTL 259.300000190734863nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)47888281783007655Rat
2317586Eae25Experimental allergic encephalomyelitis QTL 259.300000190734863nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)47888281783007655Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478885890102684881Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)481006124120102625Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general number of animals used: 794 G10 generation rats from the advanced intercross line 2317591
qtl_general software used: R/QTL 2317591
qtl_general inducing agent: myelin oligodendrocyte glycoprotein aa1-125 2317591
qtl_general this region is responsible for the severity and susceptibility of the disease and extends 80.9 Mb; also associated to weight loss 2317591
qtl_general measurement method: animals were killed 28-40 days after immunization and Eae scored on the scale of 0-4; when the disease was severe the rats were killed 2317591