Aia25 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Aia25 (Adjuvant induced arthritis QTL 25) Rattus norvegicus

Symbol: Aia25
Name: Adjuvant induced arthritis QTL 25
RGD ID: 2317053
Trait: joint integrity trait   (VT:0010548)    
Measurement Type: right rear ankle joint diameter   (CMO:0002150)    
LOD Score: 2.69
P Value: Not Available
Variance: 7.9
Inheritance Type: dominant
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21750,909,196 - 60,781,426RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01753,475,276 - 63,675,975RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01751,171,794 - 65,440,692RGDRnor5.0
RGSC_v3.41759,104,944 - 71,569,891RGDRGSC3.4
Cross Type: intercross
Strains Crossed: F344/NCrl LEW/Crl 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
F344/NCrl  (IEA)
LEW/Crl  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Genetic dissection of granulomatous enterocolitis and arthritis in the intramural peptidoglycan-polysaccharide-treated rat model of IBD. Bleich A, etal., Inflamm Bowel Dis. 2009 Jun 12;15(12):1794-1802.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
619919Arid4bAT-rich interaction domain 4B175113841951262956Rat
2402CremcAMP responsive element modulator175423888954305989Rat
2343Chrm3cholinergic receptor, muscarinic 3176000513760467250Rat
620314Ryr2ryanodine receptor 2175838992558975641Rat
628708Zp4zona pellucida glycoprotein 4175900564959012202Rat
621559Kif5bkinesin family member 5B175148987351527508Rat
620969Map3k8mitogen-activated protein kinase kinase kinase 8175338290853403216Rat
621283Mtr5-methyltetrahydrofolate-homocysteine methyltransferase175821999858308560Rat
621272Lgals8galectin 8175802465258052764Rat
621831BambiBMP and activin membrane-bound inhibitor175412125154125816Rat
3831Zeb1zinc finger E-box binding homeobox 1175194894852116018Rat
628621Gjd4gap junction protein, delta 4175734987757352446Rat
1305533Tbcetubulin folding cofactor E175129014351336090Rat
1305652Mkxmohawk homeobox175507707355156877Rat
1306354Svilsupervillin175264850252844114Rat
1310017Arhgap12Rho GTPase activating protein 12175158881051702417Rat
1307214Zfp438zinc finger protein 438175242622152547472Rat
1308097Actn2actinin alpha 2175814333458210622Rat
1308905Rab18RAB18, member RAS oncogene family175494409954976093Rat
1305675Mpp7MAGUK p55 scaffold protein 7175543993955706810Rat
1310900Mtpapmitochondrial poly(A) polymerase175332073953341500Rat
1306933Odad2outer dynein arm docking complex subunit 2175521687755409872Rat
1310644Cul2cullin 2175416908654210197Rat
1306946B3galnt2beta-1,3-N-acetylgalactosaminyltransferase 2175133492151377469Rat
1359680Ggps1geranylgeranyl diphosphate synthase 1175126326251282471Rat
1564062RGD1564062similar to ribosomal protein L27a175350348853504080Rat
1562037Jcadjunctional cadherin 5 associated175308938253130996Rat
1565969Ccnycyclin Y175738500257512860Rat
1562407WacWW domain containing adaptor with coiled-coil175592268655984286Rat
1561038Hecw1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1175067123951084536Rat
1566097Anlnl1anillin, actin binding protein-like 1175798534057995824Rat
1564129RGD1564129similar to hypothetical protein 4930474N05175415157254154198Rat
1564769Heatr1HEAT repeat containing 1175805170058093895Rat
1560525Fzd8frizzled class receptor 8175731292457320551Rat
1303252Zmynd11zinc finger, MYND-type containing 11176054266960631913Rat
1586418LOC688682similar to small nuclear ribonucleoparticle-associated protein175637209656373049Rat
1586431Rpl11-ps8ribosomal protein L11, pseudogene 8175617739356231616Rat
1586445Hspa8-ps22heat shock protein family A (Hsp70) member 8, pseudogene 22175613329856135340Rat
1586464Ddx5-ps3DEAD-box helicase 5, pseudogene 3175606927856070533Rat
1560155Dip2cdisco-interacting protein 2 homolog C176064734661032467Rat
1589973Nsa2-ps11NSA2 ribosome biogenesis factor, pseudogene 11175962502059625946Rat
1559869Lyzl1lysozyme-like 1175353043753543877Rat
1560860RGD1560860similar to ankyrin repeat domain 26175480818454847675Rat
1589709Nsfl1c-ps1NSFL1 cofactor, pseudogene 1175705725957058451Rat
1589711Rps14-ps4ribosomal protein S14, pseudogene 4175490401954904610Rat
1589712Hdac1-ps12Histone deacetylase 1, pseudogene 12175441749454419436Rat
1585457LOC686142similar to Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS)175480056554808145Rat
1590169Rps24-ps12ribosomal protein S24, pseudogene 12175287186452872255Rat
1593823LOC685434similar to protease (prosome, macropain) 28 subunit, alpha175529762755298808Rat
2318347LOC100362339ribosomal protein S19-like175136500551365544Rat
2324280Epc1enhancer of polycomb homolog 1175450335854594444Rat
2323728Snurf-ps2SNRPN upstream open reading frame, pseudogene 2175637209656373049Rat
2323728Snurf-ps2SNRPN upstream open reading frame, pseudogene 2175637307656373364Rat
6501948LOC100909729uncharacterized LOC100909729175751315957514759Rat
6498435Mki67-ps1marker of proliferation Ki-67, pseudogene 1175441437454417694Rat
7504252Hspa8-ps1heat shock protein family A (Hsp70) member 8, pseudogene 1175243664152440580Rat
7664285LOC102554214uncharacterized LOC102554214175189404751899141Rat
7635257LOC102557539uncharacterized LOC102557539175313102853133757Rat
7610313LOC102548033uncharacterized LOC102548033175933309059337521Rat
7544805LOC102553208ral guanine nucleotide dissociation stimulator-like175478059154783184Rat
7673560LOC102556228uncharacterized LOC102556228175291527352931670Rat
7742134LOC102552678uncharacterized LOC102552678175399708854016410Rat
7699281LOC102555779uncharacterized LOC102555779175761637857621486Rat
7749403LOC102548683uncharacterized LOC102548683176052111760528513Rat
9098363LOC103694114DNA repair protein RAD51 homolog 1 pseudogene175669436556695323Rat
9147085Fam95cfamily with sequence similarity 95 member C175468104054721106Rat
9152346LOC103690071interaptin-like175762154257900975Rat
9300452LOC103694107NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 pseudogene175249942752499893Rat
9472036PotedPOTE ankyrin domain family member D175794212457975149Rat
11470481LOC108348621uncharacterized LOC108348621176070470960733102Rat
11359972LOC108348578uncharacterized LOC108348578175423139954239004Rat
11460862Rps27-ps6ribosomal protein S27, pseudogene 6175174895251750448Rat
11403554LOC10834857760S ribosomal protein L29 pseudogene175418631254187090Rat
11476018LOC108348576uncharacterized LOC108348576175324203953263943Rat
11509198LOC108348573uncharacterized LOC108348573175258293652589268Rat
11486823LOC108348574uncharacterized LOC108348574175236311952426181Rat
41111655LOC120097845uncharacterized LOC120097845175421639254220950Rat
41139904LOC120097995small nucleolar RNA SNORA17175621668056216814Rat
41206737LOC120097864uncharacterized LOC120097864175589535555896197Rat
41173335Smokl-ps4sperm motility kinase like, pseudogene 4175446767254475557Rat
41208140LOC120097797uncharacterized LOC120097797175191948151928919Rat
41149856LOC120098025U2 spliceosomal RNA175366651953666669Rat
41125104LOC120097928SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5-like175827429558278695Rat
41156892LOC120097906uncharacterized LOC120097906175913071959138035Rat
41289469LOC120097863ral guanine nucleotide dissociation stimulator-like175474578054748331Rat
41373608LOC120097886ral guanine nucleotide dissociation stimulator-like175466487154667458Rat
41106420LOC120097736uncharacterized LOC120097736175180036251841519Rat
41377181LOC120097915uncharacterized LOC120097915175824370458247835Rat
40949735LOC120097757uncharacterized LOC120097757175328659353305454Rat
40985311Trnaa-agc37transfer RNA alanine (anticodon AGC) 37175719764257197722Rat
40987786LOC120097980U1 spliceosomal RNA175320548053205580Rat
40965894LOC120097983small nucleolar RNA SNORA48175238417052384307Rat
41243501LOC120097813uncharacterized LOC120097813175933758259355633Rat
41313920LOC120097826uncharacterized LOC120097826175284918652856361Rat
41314205LOC120097729uncharacterized LOC120097729175208325452087110Rat
41319530LOC120097781ral guanine nucleotide dissociation stimulator-like175472078054728358Rat
41332867LOC120098026small nucleolar RNA U3175842230958422433Rat
41332883LOC120097865uncharacterized LOC120097865175370591453712134Rat
41054517Trnas-aga47transfer RNA serine (anticodon AGA) 47175819156958191644Rat
41151572LOC120098020U2 spliceosomal RNA175541452255414611Rat
41152666Ddx5-ps1DEAD-box helicase 5, pseudogene 1175524545455259642Rat
41267736Rps7-ps15ribosomal protein S7, pseudogene 15175832060758324029Rat
41058243LOC120097728translation initiation factor IF-2-like175211375852192794Rat
41314458LOC120097795uncharacterized LOC120097795175299128653030132Rat
41063315LOC120098009small Cajal body-specific RNA 20175582035855820490Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10348D17Mit4215176046341260463643Ratregion
10349D17Arb7221176046340560463642Ratregion
10350D17Wox12121176046350060463637Ratregion
10351D17Wox13134176046348360463633Ratregion
33790D17Mit3201175348176653481960Ratregion
33860D17Mit10231175523786855238103Ratregion
34120D17Mgh599175090909950909196Ratregion
34122D17Mgh8157175090909650909253Ratregion
34645D17Pas1339175278466452785007Ratregion
36107D17Rat29164175336728153367459Ratregion
36329D17Rat32126175583607655836425Ratregion
36329D17Rat32126175583630655836425Ratregion
37432D5Rat110206175261353452613731Ratregion
36996D17Rat31162175683672856836890Ratregion
37762D17Rat170170175949767959497857Ratregion
34821D17Rat56128175648264756482769Ratregion
35052D17Rat33126176011018860110323Ratregion
35062D17Rat30170175812456458124741Ratregion
35585D17Rat151166176078142660781592Ratregion
35791D17Rat57174175277856552778744Ratregion
40400D17Rat148143175803800658038147Ratregion
38464D17Rat79204175349882853499042Ratregion
38780D17Rat64135175558322555583355Ratregion
40114D17Rat122125176000088060000997Ratregion
40198D17Rat123168175876879458768965Ratregion
38798D17Rat150220175801245258012678Ratregion
42045D17Arb5127175869183558691962Ratregion
43090D17Rat164207175237150352371712Ratregion
42417D17Rat182233175345416153454384Ratregion
42418D17Rat68171175863292958633100Ratregion
43098D17Rat149133175816531158165446Ratregion
45478D17Got62214175125392151254135Ratregion
45480D17Got79108175881625858816366Ratregion
45481D17Got77108175854148258541590Ratregion
45482D17Got75218175996373459963952Ratregion
45484D17Got74195176001893760019130Ratregion
45485D17Wox9108175724672357246843Ratregion
60772D17Wox4162175813056958130741Ratregion
60141D17Got119132175145162351451757Ratregion
60143D17Got120128175323696653237094Ratregion
60150D17Got64146175153613751536283Ratregion
60151D17Got65143175177896751779110Ratregion
60152D17Got66179175403232454032503Ratregion
60153D17Got67225175409256754092794Ratregion
60154D17Got69196175473390454734092Ratregion
60156D17Got71144175793532457935468Ratregion
60156D17Got71144175793532457935468Ratregion
60157D17Got72269175648264756482916Ratregion
60158D17Got73269175623448356234752Ratregion
67814D17Uwm1164175233240852332682Ratregion
67814D17Uwm1164175233252852332682Ratregion
625794D17Got12598175442144154421539Ratregion
61300D17Mco3259175955501359555289Ratregion
66419D17Mco11155175233240852332679Ratregion
66419D17Mco11155175233253652332679Ratregion
1556757D17Chm26241175589768755897924Ratregion
1631948D17Got223143175108888851089031Ratregion
1635830D17Uwm3166175692621756926383Ratregion
7205844Ddx50175524549555246484Ratregion
5038724AA93023279175427528154275360Ratregion
5038726AW04837697175738158457381681Ratregion
5039010RH127461180175598408255984262Ratregion
5036699AU048913190175129509051296033Ratregion
5028629RH124435278175805806058058338Ratregion
7206236Fzd882175731770057317782Ratregion
5031650AU047604125175144638451446509Ratregion
5031690AU047474241175760185857602099Ratregion
5034482BF41563097176054527560545372Ratregion
5029510AI556320201175430366954303870Ratregion
5027119RH70526130175944187759442007Ratregion
5033159RH137808176175512602155126197Ratregion
502787519.MMHAP16FRG7.seq183175691302956913212Ratregion
5027983D19344101175127387151273972Ratregion
5028318D10S1559125175598164855981773Ratregion
5028318D10S1559125175598164855981773Ratregion
5030993BF405465207175277989052780097Ratregion
5028499AI503754101175434517154345273Ratregion
5028567C76891232175789663457896866Ratregion
5028567C76891232175789663457896866Ratregion
5055083RH143596165175834096158341126Ratregion
5053473RH142669139175189414751894488Ratregion
5053671RH142783108176064869960648807Ratregion
5055971RH144108157175595779755957954Ratregion
5056751RH144559173175536049955360672Ratregion
5056749RH144558195175127892151279116Ratregion
5056465RH144394240175751447757514718Ratregion
5056943RH144670151175254688152547032Ratregion
5058144BF386697210175118871951188929Ratregion
5050500RH134092186175415401354154198Ratregion
5050586RH134141164175821329858213462Ratregion
5051711RH94613101175430301654303116Ratregion
5044340RH130546152175176419351764345Ratregion
5044516RH130648180175308946253089642Ratregion
5045620RH131282217175265998152660198Ratregion
5045974RH131486217175897533058975547Ratregion
5048780RH133101187175544014855440335Ratregion
5047426RH132321190175521923955219429Ratregion
5045090RH130978203175332081753321022Ratregion
5049418RH133470193175264863652648829Ratregion
5042584RH129523210175503230855032525Ratregion
5039398RH127683215176063156860631783Ratregion
5039572RH127782200175497580154976001Ratregion
5040538RH128341206175738139057381596Ratregion
5041278RH128765196175152062751520825Ratregion
5074908RH138288129175521572455215853Ratregion
5075110RH138404133175189419351894528Ratregion
5074104RH137824139175496197054962109Ratregion
5075336RH138536164175430424154304405Ratregion
5074858RH138259162175114342451143586Ratregion
5076080RH138967152176064864860648800Ratregion
5077608RH139854183175127470051274883Ratregion
5078056RH140118183175152548751525670Ratregion
5078440RH140344154175127584951276003Ratregion
5073222RH137311180175738484357385023Ratregion
5074410RH138001136175128226651282402Ratregion
5066928AU048067296175536897755369274Ratregion
5067250AU047870271175394697153947242Ratregion
5067416AU047762134175558319555583329Ratregion
5068324AU047214148175373503953735187Ratregion
5068480AU047120129175322855153228680Ratregion
5069444AU046494216175473390254734105Ratregion
5064322BE114408171175497844954978620Ratregion
5061336BF396244194175126392051264114Ratregion
5061476BE111848159175731299857313157Ratregion
5086327BM386345154175505407455054228Ratregion
5082465BE119488188175497620654976394Ratregion
5087283AW531528186175817987458180060Ratregion
5089281AU049062188175979416959794357Ratregion
5081467AA998284185175127538451275571Ratregion
5081493AA998918192175133494851335140Ratregion
5081593BF420658123175359258753593619Ratregion
5090103AU049552248175876877858769026Ratregion
5081230RH142039166175731804557318211Ratregion
5084796AI102819212175152643651526648Ratregion
5084920AA800231130175148688551487015Ratregion
5083227BI275488109175427568654275795Ratregion
5081953BE118897184175195080151950985Ratregion
5083767AI598891105175416915254169257Ratregion
5503076Actn2121175817097158172160Ratregion
5507549G06312246176063161260631858Ratregion
5503821MARC_33810-33811:1053549243:1283175451715454517437Ratregion
5507699GDB:131819860175428260354282663Ratregion
5507709UniSTS:25682101176063174660631847Ratregion
5504718PMC84149P1396175439776454398162Ratregion
5504306D10S1311E916175265626052657176Ratregion
5504308D10S1340E111176063174660631857Ratregion
5504887ha30461560175742191857423478Ratregion
5504999Fzd8155175731681457316969Ratregion
5504472PMC21940P1246175897512058975366Ratregion
5507129UniSTS:224716174175430307754303251Ratregion
5507271fc41h02.x1817175992373059924675Ratregion
5507287fb54b04.x10176000564260006974Ratregion
5507287fb54b04.x10176000564260006996Ratregion
5500951MARC_9759-9760:996688576:1309175490413854904449Ratregion
5500741G26357217176062989760630114Ratregion
5500793stSG625620867175930361859304485Ratregion
5501436Snrpn358175637213156372489Ratregion
5502194MARC_8191-8192:996688382:1782175099631750997099Ratregion
5505530A005N471694175787883057880524Ratregion
Position Markers

Flank 1: (D17Rat151)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21760,781,426 - 60,781,592 (-)MAPPER
Rnor_6.01763,675,975 - 63,676,140NCBI
Rnor_5.01765,440,692 - 65,440,857UniSTS
RGSC_v3.41771,569,891 - 71,570,057RGD
RGSC_v3.41771,569,892 - 71,570,057UniSTS
RGSC_v3.11771,580,725 - 71,580,890RGD
RH 3.4 Map17587.2RGD
RH 3.4 Map17587.2UniSTS
RH 2.0 Map17499.9RGD
SHRSP x BN Map1732.6599RGD
Cytogenetic Map17q12.1UniSTS
Flank 2: (D17Mgh5)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21750,909,099 - 50,909,196 (+)MAPPER
Rnor_6.01753,475,180 - 53,475,276NCBI
Rnor_5.01751,171,698 - 51,171,794UniSTS
RGSC_v3.41759,104,847 - 59,104,944RGD
RGSC_v3.41759,104,848 - 59,104,944UniSTS
RGSC_v3.11759,107,688 - 59,107,785RGD
Celera1746,929,911 - 46,930,007UniSTS
RH 3.4 Map17532.99UniSTS
RH 3.4 Map17532.99RGD
RH 2.0 Map17455.1RGD
SHRSP x BN Map1730.3699RGD
FHH x ACI Map1736.6499RGD
Cytogenetic Map17q12.1UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
2313854Bp343Blood pressure QTL 3433.9life span trait (VT:0005372)age at time of death (CMO:0001193)173199078450909196Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
1358295Aocep1Aortic cell protein QTL 16.10.00000071thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174135465160463643Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)174207316069599340Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174207316069599340Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)175089090860781592Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)175089090860781592Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
2317053Aia25Adjuvant induced arthritis QTL 252.69joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)175090919660781426Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)175402992960463637Rat
70210Cm15Cardiac mass QTL 156.5heart right ventricle mass (VT:0007033)heart right ventricle wet weight (CMO:0000072)175724672370156904Rat
1600398Edcs5Endometrial carcinoma susceptibility QTL 52.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)175724672370852846Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)175724684382046127Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)175900564977910000Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)176078142686533673Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general number of animals used: 168 F2 females 2316974
qtl_general inducing agent: peptidoglycan-polysaccharide (PG-PS) polymers 2316974
qtl_general measurement method: animals were anesthetized, intestines exposed and 0.05 mL PG-PS suspension was injected; after 24 days these animals were exsanguinated and joint diameter of the right rear ankle measured on 17th day of the treatment 2316974
qtl_general software used: MapQTL software, Student's t-tests, median tests 2316974