Wbc4 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Wbc4 (White blood cell count QTL 4) Rattus norvegicus

Symbol: Wbc4
Name: White blood cell count QTL 4
RGD ID: 2317047
Trait: leukocyte quantity   (VT:0000217)    
Measurement Type: white blood cell count   (CMO:0000027)    
LOD Score: Not Available
P Value: 0.01
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.271 - 35,342,956RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.071 - 38,119,654RGD_MAPPER_PIPELINERnor6.0
Rnor_5.071 - 38,285,714RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.471 - 36,741,943RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: F344/NCrl LEW/Crl 



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
F344/NCrl  (IEA)
LEW/Crl  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Genetic dissection of granulomatous enterocolitis and arthritis in the intramural peptidoglycan-polysaccharide-treated rat model of IBD. Bleich A, etal., Inflamm Bowel Dis. 2009 Jun 12;15(12):1794-1802.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Peak: (D7Rat63)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2712,842,835 - 12,843,077 (-)MAPPER
Rnor_6.0715,619,534 - 15,619,775NCBI
Rnor_5.0715,785,594 - 15,785,835UniSTS
RGSC_v3.4714,454,589 - 14,454,830UniSTS
RGSC_v3.4714,029,056 - 14,029,318UniSTS
RGSC_v3.4714,454,482 - 14,454,831RGD
Celera711,732,360 - 11,732,587UniSTS
Celera710,529,808 - 10,530,070UniSTS
RGSC_v3.1714,454,589 - 14,454,830RGD
RH 3.4 Map766.8RGD
RH 3.4 Map766.8UniSTS
SHRSP x BN Map74.6RGD
SHRSP x BN Map74.6UniSTS
FHH x ACI Map72.2399RGD


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general number of animals used: 168 F2 females 2316974
qtl_general measurement method: animals were anesthetized, intestines exposed and 0.05 mL PG-PS suspension was injected; after 24 days these animals were exsanguinated and white blood cell count taken from cardiac blood samples 2316974
qtl_general software used: MapQTL software, Student's t-tests, median tests 2316974
qtl_general inducing agent: peptidoglycan-polysaccharide (PG-PS) polymers 2316974