Aia14 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Aia14 (Adjuvant induced arthritis QTL 14) Rattus norvegicus

Symbol: Aia14
Name: Adjuvant induced arthritis QTL 14
RGD ID: 2317041
Trait: joint integrity trait   (VT:0010548)    
Measurement Type: left rear ankle joint diameter   (CMO:0002149)    
LOD Score: 3.29
P Value: Not Available
Variance: 8.6
Inheritance Type: additive
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0271,495,404 - 116,495,404RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0291,248,901 - 136,248,901RGDRnor5.0
Cross Type: intercross
Strains Crossed: F344/NCrl LEW/Crl 



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
F344/NCrl  (IEA)
LEW/Crl  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Genetic dissection of granulomatous enterocolitis and arthritis in the intramural peptidoglycan-polysaccharide-treated rat model of IBD. Bleich A, etal., Inflamm Bowel Dis. 2009 Jun 12;15(12):1794-1802.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Peak: (D2Rat26)
Rat AssemblyChrPosition (strand)Source
Rnor_6.0293,995,316 - 93,995,492NCBI
Rnor_5.02113,748,813 - 113,748,989UniSTS
Celera287,379,853 - 87,380,029UniSTS
RH 3.4 Map2572.0RGD
RH 3.4 Map2572.0UniSTS
RH 2.0 Map2480.8RGD
SHRSP x BN Map236.5198RGD
FHH x ACI Map243.1499RGD


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general measurement method: animals were anesthetized, intestines exposed and 0.05 mL PG-PS suspension was injected; after 24 days these animals were exsanguinated and joint diameter of the left rear ankle measured on 24th day of the treatment 2316974
qtl_general software used: MapQTL software, Student's t-tests, median tests 2316974
qtl_general inducing agent: peptidoglycan-polysaccharide (PG-PS) polymers 2316974
qtl_general number of animals used: 168 F2 females 2316974