Ean2 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Ean2 (Experimental allergic neuritis QTL 2) Rattus norvegicus

Symbol: Ean2
Name: Experimental allergic neuritis QTL 2
RGD ID: 2306794
Trait: nervous system integrity trait   (VT:0010566)    
Measurement Type: IFNG-secreting splenocyte count   (CMO:0002122)    
LOD Score: 6.4
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2483,428,419 - 95,853,334RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0484,475,257 - 97,479,149RGD_MAPPER_PIPELINERnor6.0
Rnor_5.04149,135,946 - 162,264,045RGDRnor5.0
RGSC_v3.4482,700,691 - 96,313,512RGDRGSC3.4
Cross Type: intercross
Strains Crossed: Kini:DA,PVG-G12 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Advanced intercross line mapping suggests that ncf1 (ean6) regulates severity in an animal model of guillain-barre syndrome. Huberle A, etal., J Immunol. 2009 Apr 1;182(7):4432-8.
Related QTLs

Related QTL Description Reference
Cia3 maps to same region RGD:2306769


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
68332Pde1cphosphodiesterase 1C48530085885777948Rat
70547Crhr2corticotropin releasing hormone receptor 248422289784265924Rat
2141Aqp1aquaporin 148448251284494690Rat
2038Adcyap1r1ADCYAP receptor type I48459355884642700Rat
631345Abcg2ATP binding cassette subfamily G member 248767624187802757Rat
2688Ghrhrgrowth hormone releasing hormone receptor48449815984532847Rat
620960Hint1-ps1histidine triad nucleotide binding protein 1, pseudogene 149210099492101568Rat
628647Ppp1r17protein phosphatase 1, regulatory subunit 1748521359585230607Rat
1304876Ggctgamma-glutamyl cyclotransferase48412292184129327Rat
735071RSA-14-44RSA-14-44 protein49525165795253029Rat
3729Sncasynuclein alpha48969642089797240Rat
69251Hpgdshematopoietic prostaglandin D synthase49436842694397931Rat
68368Grid2glutamate ionotropic receptor delta type subunit 249241501993892472Rat
1307803Herc3HECT and RLD domain containing E3 ubiquitin protein ligase 348795220288042492Rat
1307592Lin28clin-28 homolog C (C. elegans)49541756695420497Rat
1306645Znrf2zinc and ring finger 248395040684032676Rat
708559Wipf3WAS/WASL interacting protein family, member 348355007583629929Rat
1311705Fkbp14FKBP prolyl isomerase 1448370553183721515Rat
1308501Ppm1kprotein phosphatase, Mg2+/Mn2+ dependent, 1K48761219887638993Rat
1309807Fam13afamily with sequence similarity 13, member A48805652188155782Rat
1312013Nt5c3a5'-nucleotidase, cytosolic IIIA48616164286204671Rat
1311080Ndnfneuron-derived neurotrophic factor49494474994987414Rat
1310809Lancl2LanC like glutathione S-transferase 248744182187483707Rat
1308655Lsm5LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated48595107385954289Rat
1549777Vom1r71vomeronasal 1 receptor 7148653684786538197Rat
1311589Prr15proline rich 1548343200283435582Rat
1306494Vopp1VOPP1 WW domain binding protein48736367887432747Rat
1307856Gars1glycyl-tRNA synthetase 148417159684212609Rat
1310317Kbtbd2kelch repeat and BTB domain containing 248602794786050266Rat
1309640Smarcad1SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1`49431144194379184Rat
1561131Itprid1ITPR interacting domain containing 148501526485172457Rat
1563940Plekha8pleckstrin homology domain containing A848372347083774081Rat
1564615Avl9AVL9 cell migration associated48596149386008347Rat
1560028Qrfprlpyroglutamylated RFamide peptide receptor like49467837094757034Rat
1565731Ccser1coiled-coil serine-rich protein 149015387391391441Rat
1563162Rps7-ps20ribosomal protein S7, pseudogene 2048759277387602036Rat
1549721Vom1r68vomeronasal 1 receptor 6848638056786381478Rat
1549722Vom1r69vomeronasal 1 receptor 6948639457186395479Rat
1560999Scrn1secernin 148363212583694225Rat
1359257Vom1r79vomeronasal 1 receptor 7948691076686912251Rat
1562269Nod1nucleotide-binding oligomerization domain containing 148406087184111668Rat
1549695Vom1r74vomeronasal 1 receptor 7448674378186744692Rat
1549696Vom1r86vomeronasal 1 receptor 8648719852587199433Rat
1549699Vom1r88vomeronasal 1 receptor 8848734693387347826Rat
1549700Mturnmaturin, neural progenitor differentiation regulator homolog48380752883828494Rat
1549704Vom1r78vomeronasal 1 receptor 7848687204986872966Rat
1549708Vom1r67vomeronasal 1 receptor 6748626771986268663Rat
1549709Vom1r72vomeronasal 1 receptor 7248662671886627617Rat
1549710Vom1r70vomeronasal 1 receptor 7048644777886449039Rat
1549714Vom1r76vomeronasal 1 receptor 7648678181586782714Rat
1549715Vom1r73vomeronasal 1 receptor 7348668476586685682Rat
1549744Vom1r66vomeronasal 1 receptor 6648628841586289326Rat
1549746Vom1r82vomeronasal 1 receptor 8248704874187049637Rat
1549747Vom1r80vomeronasal 1 receptor 8048695493286955833Rat
1359218Vom1r77vomeronasal 1 receptor 7748680140086802317Rat
1549731Vom1r83vomeronasal 1 receptor 8348711393687114844Rat
1549732Vom1r85vomeronasal 1 receptor 8548716095987161867Rat
1549753Vom1r84vomeronasal 1 receptor 8448713607487136982Rat
1549756Vom1r87vomeronasal 1 receptor 8748725550387256755Rat
1549757Fkbp9FKBP prolyl isomerase 948610625686156723Rat
1564699Hmgb1-ps19high-mobility group box 1, pseudogene 1949574279595743265Rat
1549765Vom1r81vomeronasal 1 receptor 8148697716786978099Rat
1560845Vom1r-ps73vomeronasal 1 receptor pseudogene 7348706579587066329Rat
1587188Eif4g1-ps3eukaryotic translation initiation factor 4 gamma 1, pseudogene 349559026595592593Rat
1587189Nono-ps10non-POU domain containing, octamer-binding, pseudogene 1049415739794158751Rat
1587190Vom1r-ps74vomeronasal 1 receptor pseudogene 7448723150487232398Rat
1559612Tigd2tigger transposable element derived 248841436688417458Rat
1565524PyurfPIGY upstream open reading frame48750185987505494Rat
1587248Mmrn1multimerin 148987540889950814Rat
1587249Ppid-ps16peptidylprolyl isomerase D, pseudogene 1648785508187856880Rat
1587250Tubg1-ps4tubulin, gamma 1, pseudogene 448695738286958820Rat
1584123Nap1l5nucleosome assembly protein 1-like 548802267088024988Rat
1585226Hnrnpa1-ps32heterogeneous nuclear ribonucleoprotein A1, pseudogene 3248621647386218622Rat
1582950Vom1r-ps71vomeronasal 1 receptor pseudogene 7148671349186714388Rat
1562793Neurod6neuronal differentiation 648484665984849905Rat
1565171Atoh1atonal bHLH transcription factor 149391206893914163Rat
1584130Vom1r-ps70vomeronasal 1 receptor pseudogene 7048634301886343928Rat
1561739Herc6HECT and RLD domain containing E3 ubiquitin protein ligase family member 648752447087566895Rat
1565690Gprin3GPRIN family member 348856370888657603Rat
1562590Mindy4MINDY lysine 48 deubiquitinase 448435866084469189Rat
1565107Rpsa-ps19ribosomal protein SA, pseudogene 1948586753285868460Rat
1591097Eno1-ps7enolase 1, pseudogene 748987254889873844Rat
1585214Vom1r65vomeronasal 1 receptor 6548623591286245705Rat
1587548Havcr1-ps1hepatitis A virus cellular receptor 1, pseudogene 149563296895633283Rat
1588732Tnip3TNFAIP3 interacting protein 349486725894908780Rat
1597087Inmtindolethylamine N-methyltransferase48431819784322493Rat
1596167Vom1r-ps72vomeronasal 1 receptor pseudogene 7248701153087012437Rat
1597453Hsp90aa1-ps1heat shock protein 90 alpha family class A member 1, pseudogene 148679106886796467Rat
1593482Acbd5-ps1acyl-CoA binding domain containing 5, pseudogene 148826755188268264Rat
1596849Vom1r-ps111vomeronasal 1 receptor pseudogene 11148730700087307908Rat
1588783Ptma-ps1prothymosin alpha, pseudogene 149406540194065784Rat
1588700Prdm5PR/SET domain 549507573695237921Rat
2316407Vom1r-ps69vomeronasal 1 receptor pseudogene 6948632957886330574Rat
2322105Senp6-ps1SUMO specific peptidase 6, pseudogene 148855134588555553Rat
2323070Selenot-ps1selenoprotein T, pseudogene 148639863886399185Rat
2321912Ppp6c-ps1protein phosphatase 6, catalytic subunit, pseuidogene 148997047089997261Rat
2325113LOC10035961360S ribosomal protein L12-like48414816584152462Rat
6487873Tubg1-ps2tubulin, gamma 1, pseudogene 248671611286717437Rat
6500991LOC100909941uncharacterized LOC10090994148387056083875187Rat
7509699LOC102551107uncharacterized LOC10255110748454311884560009Rat
7537419Tomm7-ps3translocase of outer mitochondrial membrane 7, pseudogene 348373880383743666Rat
7685582LOC102553885uncharacterized LOC10255388548369316083711573Rat
7724284LOC102550746uncharacterized LOC10255074648428875284310594Rat
7703180LOC102550675uncharacterized LOC10255067548415456384170509Rat
9351699LOC10369489440S ribosomal protein S6 pseudogene48681994286820686Rat
9386529Ywhaq-ps4tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta, pseudogene 449449111694491862Rat
9290612LOC10369214440S ribosomal protein S6 pseudogene48684360986845120Rat
9264819Tshr-ps1thyroid stimulating hormone receptor, pseudogene 149214265692143138Rat
11450417LOC108350840uncharacterized LOC10835084049087966590931441Rat
11451272LOC108350862uncharacterized LOC10835086248876271388780061Rat
11440908LOC108350839high mobility group protein B1-like49130690291309095Rat
11356528LOC108350861glyceraldehyde-3-phosphate dehydrogenase pseudogene48625213086253132Rat
11405111Vom1r75vomeronasal 1 receptor 7548675662486757556Rat
41323200LOC120102581U6 spliceosomal RNA49528482095284926Rat
41168976Trnat-agu9transfer RNA threonine (anticodon AGU) 948552640985526483Rat
41250383LOC120102287uncharacterized LOC12010228748794191487952110Rat
41381715LOC120102288uncharacterized LOC12010228848944218589475598Rat
41386173Trnal-aag20transfer RNA leucine (anticodon AAG) 2049503448895034569Rat
41328136LOC120102650small nucleolar RNA SNORA4849582653795826676Rat
41361057Rpl21-ps8ribosomal protein L21, pseudogene 849578372795784432Rat
41177763LOC120102688small nucleolar RNA SNORA1748581335885813483Rat
41392412LOC120102697small nucleolar RNA SNORA1748824063988240769Rat
41193354LOC120102493uncharacterized LOC12010249349329282193299590Rat
41345109Hsp90aa1-ps7heat shock protein 90 alpha family class A member 1, pseudogene 748663089386631975Rat
41396160LOC120102675small nucleolar RNA SNORA1748411420284114328Rat
41195085LOC120102492uncharacterized LOC12010249249081616490869483Rat
41269840Nudt1-ps1nudix hydrolase 1, pseudogene 149438167994382041Rat
41347976Eef1b2-ps1eukaryotic translation elongation factor 1 beta 2, pseudogene 148344887783449544Rat
41104383LOC120102494uncharacterized LOC12010249449389284393911169Rat
40926323LOC120102600U6 spliceosomal RNA49362423893624344Rat
40929032LOC120102616U7 small nuclear RNA49406112494061185Rat
40966591Apoo-ps4apolipoprotein O, pseudogene 448531798985318559Rat
40991721LOC120102726small nucleolar RNA SNORA1749499311894993219Rat
40994091Paics-ps3phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase, pseudogene 349164710291648078Rat
41243681LOC120102661small nucleolar RNA SNORA1748579175085791883Rat
41312835LOC120102520uncharacterized LOC12010252048894704088947688Rat
41079727Trnas-aga44transfer RNA serine (anticodon AGA) 4448548230785482381Rat
41255876LOC120102647small nucleolar RNA SNORA4849414489094145033Rat
41221465LOC120102615U7 small nuclear RNA49406097694061038Rat
41258840LOC120102567U6 spliceosomal RNA48784604487846150Rat
41297101LOC120102286uncharacterized LOC12010228648618482886206190Rat
41059287LOC120102620U7 small nuclear RNA49171696791717031Rat
41043092LOC120102284uncharacterized LOC12010228448480010684817508Rat
41044388LOC120102751U2 spliceosomal RNA49015113790151328Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
33905D4Mit1129549136052791360801Ratregion
36378D4Mgh3321248615232386152535Ratregion
35286D4Rat3715149330831593308457Ratregion
35409D4Rat3414948537942185379614Ratregion
36978D4Rat3813949585319395853334Ratregion
36544D4Rat7716549512805695128221Ratregion
35669D4Rat3516449136661091366774Ratregion
35721D4Rat7617848525374885253946Ratregion
38262D4Rat10321648342841983428649Ratregion
40586D4Rat23122648865668188656903Ratregion
40640D4Rat17124848821695788217207Ratregion
40020D4Rat17316049248951492489678Ratregion
39520D4Rat17023748423638084236623Ratregion
42306D4Rat26614348472868084728829Ratregion
42707D4Rat23023448753215187532391Ratregion
40856D4Rat17414249422276294222908Ratregion
41586D4Rat17213349466112194661248Ratregion
43820D4Got7527349261823292618505Ratregion
43821D4Got6520248345449583454697Ratregion
60803D4Wox432549144941691449741Ratregion
60448D4Got6328848367604183676329Ratregion
60449D4Got6723848590100185901239Ratregion
60451D4Got6919348725177587251968Ratregion
60452D4Got7028849319926293199550Ratregion
60454D4Got7227549078304890783319Ratregion
60455D4Got7320549401004894010253Ratregion
60456D4Got7416349299129992991462Ratregion
60457D4Got7615548756588187566036Ratregion
60458D4Got7727849336204893362326Ratregion
60461D4Got8016549512799195128156Ratregion
60462D4Got8117749472249694722672Ratregion
62509D4Uia732548828201988282339Ratregion
1630451D4Got2609548547841985478509Ratregion
1631098D4Got21314349321653693216679Ratregion
1628883D4Got29021849166258191662799Ratregion
1629824D4Got29122648431554284315744Ratregion
1641561D4Wox3529248362933483629626Ratregion
7205950Aqp138348449206484493114Ratregion
7206014Neurod611648484833684848452Ratregion
7205888px-35f113548912259089122725Ratregion
7206492UniSTS:546664158149391229393913874Ratregion
5038892RH12739321848382816583828383Ratregion
5039208RH12757419748449428284494479Ratregion
5037053WI-1159211748602797786028094Ratregion
5031376PMC153617P199448969698589697976Ratregion
5026176RH13120519048431826084318450Ratregion
5026374RH13196118448523038585230569Ratregion
5031706AU04742120848765572087655928Ratregion
5026580RH13275718648343478583434971Ratregion
5034586BF41650114849282631592826463Ratregion
5029419Snca13048977854189778671Ratregion
5032275AI84659012148464250384642624Ratregion
5029737BE10224719448343187683432070Ratregion
5027313D4448014148484724284847383Ratregion
5032911RH13693918148353560583535785Ratregion
5025016BB38566810249391401793914119Ratregion
5033101RH13760114548533083385330978Ratregion
5030593BF41017511248533457485334686Ratregion
5025656RH12915515048616200086162150Ratregion
5028456AI4285589848780216187802259Ratregion
5053517RH14269410148417768484177785Ratregion
5053647RH14276924548856376788564012Ratregion
5056613RH14447915648620088486201040Ratregion
5056987UniSTS:23402926748969673889697005Ratregion
5057462BF41870621848995016289950380Ratregion
5057550BE09553015348365145683651609Ratregion
5055187RH14365611048779599787796107Ratregion
5056527RH14443013248362422183624353Ratregion
5056669RH14451110449214266292142766Ratregion
5055251RH14369318448802469688024880Ratregion
5058296BF38698015448484735284847506Ratregion
5049816RH13369822048362719383627413Ratregion
5053353RH14259910849080102690801134Ratregion
5050038RH13382619148421088084212302Ratregion
5043958RH13032819048841698488417174Ratregion
5043440RH13002719248370556583705757Ratregion
5040978RH12859319548743248787432682Ratregion
5043566RH13009818048446704184467221Ratregion
5045546RH13124020548377371783773922Ratregion
5048714RH13306320149431222094312787Ratregion
5046574RH13183220548403221284032417Ratregion
5045118RH13099421548402750684027721Ratregion
5046104RH13156021048370696683707176Ratregion
5046612RH13185421848802107188021289Ratregion
5046648RH13187418048644365186443831Ratregion
5049502RH13351818048750385087504030Ratregion
5049550RH13354518049498159594981775Ratregion
7191236Neurod6101448484744184848455Ratregion
5043642RH13014318248763662987636811Ratregion
5043794RH13023118048780254087802720Ratregion
5041378RH12882318448616170686161890Ratregion
5074280RH13792518848744186787442054Ratregion
5075900RH13886213748411960484119741Ratregion
5076928RH13946018048802294688023126Ratregion
5075416RH13858114048798666787988172Ratregion
5077336RH13969818848387452283875268Ratregion
5077524RH13980519948422299984223198Ratregion
5079854RH14124118048918590389185985Ratregion
5077876RH14001118048752456887524748Ratregion
5077896RH14002221348363217583632388Ratregion
5078500RH14037924048421683384217073Ratregion
5078802RH14056019048381574683815936Ratregion
5071978RH13539421448445737284458689Ratregion
5071978RH13539421448445847584458689Ratregion
5074484RH13804316149389218293892343Ratregion
5066844AU04811727649409150994091763Ratregion
5068790AU0469298749114043091140517Ratregion
5060178BF40062924849431871694318964Ratregion
5062150BE10626616348446467484464837Ratregion
5063854BE12007216648423061284230778Ratregion
5060972BF40157915148531084085310991Ratregion
5063082BF39830717448748294987483123Ratregion
5066336PMC153617P210548969646189696566Ratregion
5066426AU04836324348994718789947430Ratregion
5066554AU04828813748870520588705342Ratregion
5086339AA87551321048402369984023909Ratregion
5087201AI22947118148411721684117397Ratregion
5087899Grid29649385576393855859Ratregion
5087897Grid212849385566493855792Ratregion
5089153AU04898610748434603084346065Ratregion
5089555AU04922517249376086793761041Ratregion
5088621AU04867824848368126283681511Ratregion
5089985AU04948124149078853490788775Ratregion
5087616PMC57740P124548484750584847750Ratregion
5085004AI22973319048412440084125952Ratregion
5088345AU04851314749526102095261167Ratregion
5088623AU04867919948349313983493340Ratregion
5082595BE11981315649017649890176650Ratregion
5084510AI40975519748804190288042100Ratregion
5086262BM38483521048420498784205197Ratregion
5083127BF39081515049375655593756705Ratregion
5081639BE11774115748371337383713530Ratregion
5086843AA81923221448602814086028352Ratregion
5503105CRHR213748422524784225787Ratregion
5504224RH7556324848679577886796026Ratregion
5504969Tshr11249214266292142774Ratregion
5505820UniSTS:495551105448638051986381573Ratregion
5505760UniSTS:492639105048638051986381569Ratregion
5507175UniSTS:22501117848769912887699306Ratregion
5502718NEUROD643748484735884847795Ratregion
Position Markers

Flank 1: (D4Rat103)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2483,428,419 - 83,428,649 (+)MAPPER
Rnor_6.0484,475,257 - 84,475,486NCBI
Rnor_5.04149,135,946 - 149,136,175UniSTS
RGSC_v3.4482,700,691 - 82,700,921RGD
RGSC_v3.4482,700,692 - 82,700,921UniSTS
RGSC_v3.1482,985,313 - 82,985,543RGD
Celera478,304,079 - 78,304,308UniSTS
SHRSP x BN Map441.93RGD
SHRSP x BN Map441.93UniSTS
Peak: (D4Rat231)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2488,656,681 - 88,656,903 (+)MAPPER
Rnor_6.0489,777,552 - 89,777,772NCBI
Rnor_5.04154,593,964 - 154,594,184UniSTS
RGSC_v3.4488,462,327 - 88,462,549RGD
RGSC_v3.4488,462,328 - 88,462,549UniSTS
RGSC_v3.1488,706,752 - 88,706,974RGD
SHRSP x BN Map443.1UniSTS
SHRSP x BN Map443.1RGD
FHH x ACI Map454.64RGD
Flank 2: (D4Rat38)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2495,853,193 - 95,853,334 (+)MAPPER
Rnor_6.0497,479,009 - 97,479,149NCBI
Rnor_5.04162,263,905 - 162,264,045UniSTS
RGSC_v3.4496,313,186 - 96,313,326UniSTS
RGSC_v3.4496,313,180 - 96,313,512RGD
RGSC_v3.1496,557,667 - 96,557,807RGD
Celera490,553,749 - 90,553,889UniSTS
RH 3.4 Map4603.0RGD
RH 3.4 Map4603.0UniSTS
SHRSP x BN Map448.75UniSTS
SHRSP x BN Map448.75RGD
FHH x ACI Map459.12RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711443291360801Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)45843213392991462Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)460220938105220938Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)460220938105220938Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658103194791Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46293326987483707Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in mean arterial blood pressure (CMO:0002035)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in systolic blood pressure (CMO:0000747)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in pulse pressure (CMO:0001882)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)46588210796130297Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)470808386115808386Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)470808386115808386Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)473630210118630210Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)473630210118630210Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478885890102684881Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)481006124120102625Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
2306794Ean2Experimental allergic neuritis QTL 26.4nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)48342841995853334Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)484728680129854654Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)485253748150276390Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486730991131730991Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487327165132327165Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487327165132327165Rat
2317587Eae26Experimental allergic encephalomyelitis QTL 26nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)488656681103194984Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_disease animals treated with agonist NADPH oxidase complex for Ncf1 gene showed dramatic reduction in disease score 2306769
qtl_general measurement method: rats were anesthetized by ether inhalation then bPNM (bovine peripheral nerve myelin) dissolved in PBS was injected at the base of the tail then scored: 0, normal; 1, less active; 2, limp tail; 3, absent righting; 4, gait ataxia; 5, mild paresis; 6, moderate paresis; 7, severe paraparesis; 8, tetraparesis; 9, moribund; 10, death; body weight was taken every second day 2306769
qtl_general number of animals used: 215 males and 235 females; 8-14 weeks old 2306769
qtl_general region responsible for strongly regulating IFN-gamma secretion by T cell activity 2306769
qtl_general inducing agent: bPNM (bovine peripheral nerve myelin) 2306769