Ean1 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Ean1 (Experimental allergic neuritis QTL 1) Rattus norvegicus

Symbol: Ean1
Name: Experimental allergic neuritis QTL 1
RGD ID: 2306790
Trait: nervous system integrity trait   (VT:0010566)    
Measurement Type: experimental autoimmune neuritis severity score   (CMO:0001528)    
LOD Score: Not Available
P Value: 0.05
Variance: Not Available
Position No map positions available.
Cross Type: intercross
Strains Crossed: LEW.1AV1 

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Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Measurement Method

Vertebrate Trait

Rat Strain


References - curated
# Reference Title Reference Citation
1. MHC and non-MHC gene regulation of disease susceptibility and disease course in experimental inflammatory peripheral neuropathy. de Graaf KL, etal., J Neuroimmunol. 2004 Oct;155(1-2):73-84.


Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch

Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general number of animals used: 41 males 14-20 weeks old 2306736
qtl_general inducing agent: bPNM (bovine peripheral nerve myelin) or P2 58-81 2306736
qtl_general measurement method: rats were anesthetized with methoxyflurane then 2mg bPNM (bovine peripheral nerve myelin) in saline or P2 58-81 in saline was injected at the base of the tail then scored: grade 1, tail weakness or paralysis; grade 2, gait ataxia hind leg paraparesis; grade 3, hind leg paralysis; grade 4, complete paralysis 2306736
qtl_general software used: ANOVA 2306736
qtl_general MHC class II genes are major susceptibility genes 2306736