Ean6 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Ean6 (Experimental allergic neuritis QTL 6) Rattus norvegicus

Symbol: Ean6
Name: Experimental allergic neuritis QTL 6
RGD ID: 2306789
Trait: nervous system integrity trait   (VT:0010566)    
Measurement Type: experimental autoimmune neuritis severity score   (CMO:0001528)    
LOD Score: 4.9
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21219,610,870 - 24,139,202RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01222,650,702 - 27,190,240RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01224,662,983 - 29,163,190RGDRnor5.0
RGSC_v3.41220,932,559 - 25,367,251RGDRGSC3.4
Cross Type: Not Available
Strains Crossed: Kini:DA,PVG-G12 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Ncf1 is a candidate Gene for Ean6

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Advanced intercross line mapping suggests that ncf1 (ean6) regulates severity in an animal model of guillain-barre syndrome. Huberle A, etal., J Immunol. 2009 Apr 1;182(7):4432-8.
Related QTLs

Related QTL Description Reference
Pia4 maps to same region RGD:2306769
Eae5 maps to same region RGD:2306769


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
68425Cldn3claudin 3122170853821710010Rat
69430Stx1asyntaxin 1A122164197121670022Rat
619719Mdh2malate dehydrogenase 2122089426920907225Rat
61307Ncf1neutrophil cytosolic factor 1122248538222494647Rat
69284Sh2b2SH2B adaptor protein 2122042705720456845Rat
62019Clip2CAP-GLY domain containing linker protein 2122216304422227023Rat
62055Limk1LIM domain kinase 1122202669722060605Rat
69399VgfVGF nerve growth factor inducible121963731319645123Rat
620305Hip1huntingtin interacting protein 1122113331921267796Rat
628817Fzd9frizzled class receptor 9122142708421429398Rat
631346Trim50tripartite motif-containing 50122130078421317668Rat
620680Pom121POM121 transmembrane nucleoporin122127371321294299Rat
631339Plod3procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3121967638419686945Rat
68335Porcytochrome p450 oxidoreductase122095105820999198Rat
620618Cux1cut-like homeobox 1122010706220425868Rat
620856Gtf2ird1GTF2I repeat domain containing 1122225411322361052Rat
631397Lat2linker for activation of T cells family, member 2122210416322118294Rat
620400MlxiplMLX interacting protein-like122154296421577120Rat
621198Rfc2replication factor C subunit 2122212044922133576Rat
1304672Castor2cytosolic arginine sensor for mTORC1 subunit 2122257750422620182Rat
67394Elnelastin122196854422011929Rat
1304681Abhd11abhydrolase domain containing 11122168220621685331Rat
3249Serpine1serpin family E member 1121960127219611657Rat
620606Zp3zona pellucida glycoprotein 3122069054720697513Rat
62002Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma122074450020772828Rat
61306Hspb1heat shock protein family B (small) member 1122079401420795675Rat
1305845Styxl1serine/threonine/tyrosine interacting-like 1122090741020940232Rat
1305911Ap1s1adaptor related protein complex 1 subunit sigma 1121962526719635792Rat
1305370Ift22intraflagellar transport 22121975907219768859Rat
1307435Gtf2ird2GTF2I repeat domain containing 2122249836022551293Rat
1308231Rhbdd2rhomboid domain containing 2122104360521054305Rat
1310198Polr2jRNA polymerase II subunit J122054303820548590Rat
1310245Ccl24C-C motif chemokine ligand 24122110083521104832Rat
1308608Alkbh4alkB homolog 4, lysine demethylase122052403020529947Rat
1306970Ssc4dscavenger receptor cysteine rich family member with 4 domains122070293120723732Rat
1306668Fis1fission, mitochondrial 1121970855819723392Rat
1307558Rcc1lRCC1 like122254312522574042Rat
1309615Upk3buroplakin 3B122062949120638193Rat
1308926Fkbp6FKBP prolyl isomerase family member 6122131825121390350Rat
1310213Orai2ORAI calcium release-activated calcium modulator 2122050030820520428Rat
1310678Cldn15claudin 15121969816919708419Rat
1307932Cldn4claudin 4122175163821753436Rat
1309268Nsun5NOP2/Sun RNA methyltransferase 5122129363721299319Rat
1561903Tmem270transmembrane protein 270122179363121798723Rat
1563240Ervfrd-1endogenous retrovirus group FRD member 1, envelope122215121122158264Rat
1311474Tmem120atransmembrane protein 120A122094224320950908Rat
1359222Eif4heukaryotic translation initiation factor 4H122208315522099876Rat
727961Gtf2igeneral transcription factor II I122240093322476243Rat
1359442Lrwd1leucine-rich repeats and WD repeat domain containing 1122053007220543078Rat
1583828Rps13-ps4ribosomal protein S13, pseudogene 4122112530921125763Rat
1561790Dtx2deltex E3 ubiquitin ligase 2122064328920682908Rat
1583827Chmp5-ps3charged multivesicular body protein 5, pseudogene 3122214657622147671Rat
1561258Myl10myosin light chain 10121996917419982627Rat
1587769Vps37dVPS37D subunit of ESCRT-I122160921021614669Rat
1591401Col26a1collagen type XXVI alpha 1 chain121979269319938556Rat
1587868Srrm3serine/arginine repetitive matrix 3122080887820878557Rat
1589742Bud23BUD23, rRNA methyltransferase and ribosome maturation factor122162955121640758Rat
1587817Ccl26C-C motif chemokine ligand 26122110938421114336Rat
1588881Mettl27methyltransferase like 27122175754521766698Rat
1585479Abhd11-as1ABHD11 antisense RNA 1 (tail to tail)122168111821682106Rat
1565457Rasa4RAS p21 protein activator 4122055280520580177Rat
1585449Arpc5l-ps3actin related protein 2/3 complex, subunit 5-like, pseudogene 3122173477521735623Rat
1595783Dnajc30DnaJ heat shock protein family (Hsp40) member C30122162832321629389Rat
1597090Bcl7bBAF chromatin remodeling complex subunit BCL7B122149685621510202Rat
1597089Baz1bbromodomain adjacent to zinc finger domain, 1B122143198521489956Rat
1595708Prkrip1PRKR interacting protein 1122047080220491789Rat
1592588Mogat3monoacylglycerol O-acyltransferase 3121966870319669420Rat
1595038Tbl2transducin (beta)-like 2122151760021532114Rat
1598237Upk3bl1uroplakin 3B like 1122061035320616366Rat
2322870Znhit1zinc finger, HIT-type containing 1121968660619692880Rat
2323959Auts2activator of transcription and developmental regulator AUTS2122410418725194123Rat
4888576Mir702microRNA 702121968180919681915Rat
6488308Rpsa-ps7ribosomal protein SA, pseudogene 7122279671522803092Rat
6496734LOC100910802uncharacterized LOC100910802121974235519757486Rat
7489014Mir6322microRNA 6322122378000123780119Rat
7520086LOC102553484uncharacterized LOC102553484122196238721969793Rat
7587101LOC102553721uncharacterized LOC102553721122262846522635776Rat
7689818LOC102553558uncharacterized LOC102553558122213845522140424Rat
9311981LOC103691302uncharacterized LOC103691302122247302922487591Rat
9242288LOC103691506claudin-4-like122177606621776722Rat
11435442LOC108352438uncharacterized LOC108352438122366574023707081Rat
11405154LOC10835248440S ribosomal protein S14 pseudogene122206842522069114Rat
11499585LOC108352435uncharacterized LOC108352435122088043520891489Rat
41383089LOC120096124small Cajal body-specific RNA 20122163961521639747Rat
41148403LOC120096097U6 spliceosomal RNA122064436520644470Rat
41214653LOC120095913uncharacterized LOC120095913122062250520633507Rat
41344750Pnp-ps1purine nucleoside phosphorylase, pseudogene 1122389459123895813Rat
41397405LOC120095912uncharacterized LOC120095912122004641720053457Rat
41184641Rps11-ps6ribosomal protein S11, pseudogene 6122078737120791987Rat
41373117LOC120095927uncharacterized LOC120095927122341717523434982Rat
41401627Rps13-ps6ribosomal protein S13, pseudogene 6122171220021715310Rat
41198486LOC120095916uncharacterized LOC120095916122139043821401115Rat
41275322LOC120095917uncharacterized LOC120095917122127463921276764Rat
41166140Rps29-ps4ribosomal protein S29, pseudogene 4122379983923800137Rat
40951983LOC120095854uncharacterized LOC120095854122280502222815570Rat
40927760LOC120096095U6 spliceosomal RNA122072241820722523Rat
41001183LOC120095924uncharacterized LOC120095924122293268922945250Rat
40965707LOC120096096U6 spliceosomal RNA122276037022760469Rat
40992997LOC120095926uncharacterized LOC120095926122322144823319564Rat
41319237LOC120095855uncharacterized LOC120095855122285966222867915Rat
41255513LOC120095920uncharacterized LOC120095920122179357721800351Rat
41064979LOC1200960805S ribosomal RNA122147615321476268Rat
41306277LOC120095918uncharacterized LOC120095918122115005021151606Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10888D12Wox1092122089438020894469Ratregion
11051D12Mit2217121961087019611091Ratregion
11052D12Wox11196121961088619611090Ratregion
11053D12Wox12198121961088919611095Ratregion
34017D12Mit9142122184936621849508Ratregion
34417D12Mgh2163121983578919835952Ratregion
11449D12Wox14158122200342822003586Ratregion
11450D12Mgh12140122199658621996726Ratregion
11451D12Mgh13145122200341122003550Ratregion
36025D12Rat23154122413905724139202Ratregion
36344D12Mit10121122363264523632770Ratregion
37250D12Rat26201122269248122692658Ratregion
35479D12Rat8158122277945922779600Ratregion
37878D12Rat33221122114617721146418Ratregion
36538D12Rat7161121994867819948839Ratregion
35889D12Rat10155122367192823672083Ratregion
40702D12Rat69211121995043219950632Ratregion
39218D12Rat35200122291940222919596Ratregion
39236D12Rat51213122127306221273283Ratregion
41384D12Rat70154121964216619642312Ratregion
42965D12Rat92248122078029620780530Ratregion
42969D12Rat115215122408880524089002Ratregion
40986D12Rat72309122196559521965906Ratregion
44965D12Got40230121986903919869269Ratregion
44967D12Got41157121981117419811331Ratregion
44969D12Got102135122111996721120102Ratregion
44970D12Got45149122195186021952011Ratregion
44971D12Got46216122229720922297425Ratregion
44973D12Got103249122087451320874764Ratregion
44974D12Got48180122289624922896429Ratregion
44975D12Got49185122306034523060532Ratregion
44976D12Got47111122342739323427504Ratregion
44977D12Got50298122348574723486045Ratregion
44978D12Got51205122359346823593673Ratregion
44979D12Got55222122386746423867686Ratregion
60012D12Got105128121966594319666071Ratregion
60016D12Got43159122021785420218013Ratregion
629606D12Hmgc2262122199672021996983Ratregion
67290D8Arb9204122200342122003625Ratregion
67356D12Arb15202122195183521952039Ratregion
1629328D12Got217284122191328221913563Ratregion
1629647D12Got220119122088154520881664Ratregion
1637896D12Uia3216122315654923156765Ratregion
7192219Fzd9487122142886621429353Ratregion
7193095AA957504192122056484220565034Ratregion
5038976RH127441189122055290720553096Ratregion
5036352Hsp25216122079414120794468Ratregion
5039228RH127586215122173407821734293Ratregion
5039228RH127586215122173408021734293Ratregion
5037007AU049899204122300008223000286Ratregion
5035701WI-1509899122051691720517016Ratregion
7206190Eln141122201023522011026Ratregion
7206212Hspb1408122079427720795457Ratregion
5034249RH1419280122248151622481698Ratregion
5034337Ncf1165122249271622493032Ratregion
5034337Ncf1165122249271622493032Ratregion
5034339Fkbp6481122132920421329685Ratregion
5034402BE117132150122243066822430818Ratregion
5032014AU046360137122042936920429506Ratregion
5026638RH1329730122211792622118098Ratregion
5026664RH133068206122011796220118168Ratregion
5035126AI548127209122161164921611858Ratregion
5032495D5Ertd355e248122209962022099868Ratregion
5027307AI957187130122063042920630559Ratregion
5035208BM390639203122089592320896126Ratregion
5030109BE098443174122077106320771237Ratregion
5025010AU022494218122064331020643528Ratregion
5027595AI46224399122168170321681802Ratregion
5025306RH127813210122389445123894659Ratregion
5025422RH1282540122209948422099712Ratregion
5030615BE107127158122151999821520156Ratregion
5025546RH128738156122161450021614656Ratregion
5031165BE116737176122114569821145874Ratregion
5051537AU015798189122389437023894559Ratregion
5053831RH142876162121972227819722440Ratregion
5056941RH144669170122062949720629667Ratregion
5051835RH94685217122201132822011545Ratregion
5054195RH143085251122243266522432916Ratregion
5057524AW522797179121973677219736951Ratregion
5057906BI277291215122154368221543897Ratregion
5059566BE097301153122234935922349512Ratregion
5056693RH144525169122170964021709809Ratregion
5058056BF386509150122082571220825862Ratregion
5052777RH142267176121969243419692767Ratregion
5052815RH142289151122206042222060573Ratregion
5052877RH142325199121970860219708801Ratregion
5053073RH142438176122089429520894468Ratregion
5057674BE101305210122063109820631323Ratregion
5050030RH133822180122072445920724639Ratregion
5051014RH134388193122054331420544059Ratregion
5053021RH142408193122077129820771491Ratregion
5053113RH142461223122043796120438184Ratregion
5041840RH129089153122049162220491775Ratregion
5043946RH130322189122064332520643514Ratregion
5043946RH130322189122064332520643514Ratregion
5044092RH130405184122052007820520262Ratregion
5043588RH130111182122040972020409902Ratregion
5044998RH130924195122063324720633442Ratregion
5045390RH131150198122063030020630498Ratregion
5044252RH130496189122129430721294496Ratregion
5048884RH133161208122126428421264492Ratregion
5049222RH133356196122212064622120840Ratregion
5048172RH132750204121966882219669213Ratregion
5047170RH132174220122054270220543016Ratregion
5039492RH127736213122089444920894990Ratregion
5048412RH132889186122071847020718656Ratregion
5042866RH1296920121961138519611585Ratregion
5040162RH128125209122126731721267526Ratregion
7192204Fzd10179122142856621428745Ratregion
5040586RH128368216122118577921185995Ratregion
5042942RH129737159122079408320794242Ratregion
5075452RH138602130122247459322475256Ratregion
5075482RH138619128122162835221628480Ratregion
5072488RH136879157122175307421753231Ratregion
5076376RH139139184121976060319760787Ratregion
5076558RH139246236122173407821734314Ratregion
5076558RH139246236122173408021734314Ratregion
5076630RH139287223122084514020845363Ratregion
5075888RH138855217122249319322493410Ratregion
5075888RH138855217122249319322493410Ratregion
5077140RH139585207122042537620425583Ratregion
5076398RH139152186122221546122215647Ratregion
5077448RH139762188122170869021708878Ratregion
5077942RH140050185122412847924128664Ratregion
5078298RH140259199122227872422278923Ratregion
5079140RH140758133122168247121682858Ratregion
5070646RH134623186122164043221640618Ratregion
5073154RH137270199122077129120771490Ratregion
5071224RH134959188122130086021301048Ratregion
5073654RH137562247122222672922226976Ratregion
5071830RH135309202122117085121171053Ratregion
5071528RH135134220122251989022520110Ratregion
5072234RH136731142122103984321039985Ratregion
5071600RH135176180122048822720488407Ratregion
5067440AU047743166122031501620315182Ratregion
5067446AU047739171122265164822651813Ratregion
5067606AU047644180122342559823425778Ratregion
5067608AU047633193122342559823425791Ratregion
5068616AU047037210122116606721166275Ratregion
5070281RH94577178121961122919611407Ratregion
5069284AU046599190122208180822081993Ratregion
5062302BI288626185122213881522139000Ratregion
5063790AW535181183122231174822311931Ratregion
5063976BE120355168122040815620408325Ratregion
5065682BF41274694122028856420288658Ratregion
5064398BF411168226122033705820337284Ratregion
5062110BF397463207122165643321656907Ratregion
5063774AW535146159122151899021519149Ratregion
5065400AA95750490122056478220564872Ratregion
5064324AW529994209122154163221541841Ratregion
5065896AA964673117122126528921265406Ratregion
5061024BF389756218122081645220816670Ratregion
5061170BE099159165121976230319762468Ratregion
5066402AU048378133122165014821650283Ratregion
5066570AU048279137122335834823358485Ratregion
5086066AW529466165122142975021429915Ratregion
5086377BQ205524202122336094623361148Ratregion
5087114AI511394150122211828922118439Ratregion
5082979BF390551160122111409721114257Ratregion
5087446PMC180925P1753122095603620956789Ratregion
5083337BF417900202122076495320765155Ratregion
5088299AU048487168122079838820799310Ratregion
5088299AU048487168122079914220799310Ratregion
5090807AU049974208122017595020176158Ratregion
5088655AU048698165122220861222208776Ratregion
5088655AU048698165122220861222209459Ratregion
5088827AU048794232122116014721160379Ratregion
5089619AU049263194122408882824089022Ratregion
5090467AU049767193122326311323263306Ratregion
5090515AU049797289122365538623655675Ratregion
5081457Fzd9269122142861721428886Ratregion
5081461UniSTS:230793351122205904822059399Ratregion
5088143Baz1b121122148981621489937Ratregion
5082163BI280199151121963525119635402Ratregion
5082331BI274506161122197926321979424Ratregion
5082437BI274753205122247585722476062Ratregion
5088259AU048461162122287962622879788Ratregion
5085345BE100612165122257990922580081Ratregion
5081258RH142057192122052421920524411Ratregion
5081459UniSTS:230791255122142863121428886Ratregion
5086787BE107332214122051587620516090Ratregion
5085709BE101960176122081933920819515Ratregion
5085800BF388132200122148408021484280Ratregion
5086034BM383880189122345327223453461Ratregion
5502989D5Dcr13141122188159321881734Ratregion
5503867SSC3D06197122077254720772744Ratregion
5507648Eln698122198622321986921Ratregion
5503613Cldn3660122170891021709570Ratregion
5506270GDB:458569784122054586220545946Ratregion
5507319G48114154122206037922060533Ratregion
5499595Wbscr1215122209751722098178Ratregion
5499597Wbscr14147122154414321545203Ratregion
5499663MARC_6945-6946:992007577:2582122094952920950111Ratregion
5499899UniSTS:235344206121963543119635637Ratregion
5500713RH911941560122119362221195182Ratregion
5500875D5S5031483122138140521382889Ratregion
5502609RH12552482122389537023895452Ratregion
5502475RH125009259122387715623877415Ratregion
Position Markers

Flank 1: (D12Mit2)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21219,610,870 - 19,611,091 (+)MAPPER
Rnor_6.01222,650,702 - 22,650,918NCBI
Rnor_5.01224,662,983 - 24,663,199UniSTS
RGSC_v3.41220,932,560 - 20,932,776UniSTS
RGSC_v3.41220,932,559 - 20,932,776RGD
RGSC_v3.11220,922,171 - 20,922,388RGD
Celera1221,386,630 - 21,386,846UniSTS
RH 3.4 Map12280.3RGD
RH 3.4 Map12280.3UniSTS
RH 2.0 Map12205.1RGD
SHRSP x BN Map1222.7RGD
FHH x ACI Map129.01RGD
Cytogenetic Map12q11-q12UniSTS
Peak: (D12Got48)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21222,896,249 - 22,896,429 (+)MAPPER
Rnor_6.01225,915,078 - 25,915,257NCBI
Rnor_5.01227,920,502 - 27,920,681UniSTS
RGSC_v3.41224,078,927 - 24,079,106UniSTS
RGSC_v3.41224,078,926 - 24,079,106RGD
RGSC_v3.11223,942,143 - 23,942,322RGD
Celera1224,651,805 - 24,651,984UniSTS
RH 3.4 Map12356.1UniSTS
RH 3.4 Map12356.1RGD
RH 2.0 Map12254.5RGD
Flank 2: (D12Rat23)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21224,139,057 - 24,139,202 (+)MAPPER
Rnor_6.01227,190,096 - 27,190,240NCBI
Rnor_5.01229,163,046 - 29,163,190UniSTS
RGSC_v3.41225,367,106 - 25,367,251RGD
RGSC_v3.41225,367,107 - 25,367,251UniSTS
RGSC_v3.11225,230,197 - 25,230,561RGD
Celera1225,875,595 - 25,875,739UniSTS
SHRSP x BN Map1227.31UniSTS
SHRSP x BN Map1227.31RGD
FHH x ACI Map1211.22RGD
Cytogenetic Map12q12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12844949028302290Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)12931821632103380Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121107382524234895Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382528064557Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121363552330827399Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121363552335682913Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)121502518320794014Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121555082638478808Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)121587265332974238Rat
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)121961087024139202Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961088935682913Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121983578938193007Rat
631521Pia12Pristane induced arthritis QTL 128.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)122025941723672083Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
70169Eae13Experimental allergic encephalomyelitis QTL 130.032nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)122413920236638073Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_disease animals treated with agonist NADPH oxidase complex for Ncf1 gene showed dramatic reduction in disease score 2306769
qtl_general region responsible for the maximum disease score 2306769
qtl_general inducing agent: bPNM (bovine peripheral nerve myelin) 2306769
qtl_general number of animals used: 215 males and 235 females; 8-14 weeks old 2306769
qtl_general measurement method: rats were anesthetized by ether inhalation then bPNM (bovine peripheral nerve myelin) dissolved in PBS was injected at the base of the tail then scored: 0, normal; 1, less active; 2, limp tail; 3, absent righting; 4, gait ataxia; 5, mild paresis; 6, moderate paresis; 7, severe paraparesis; 8, tetraparesis; 9, moribund; 10, death; body weight was taken every second day 2306769