Bp333 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp333 (Blood pressure QTL 333) Rattus norvegicus

Symbol: Bp333
Name: Blood pressure QTL 333
RGD ID: 2303180
Previously known as: S x SHR QTL Region 1; BP QTL 1
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: diastolic blood pressure   (CMO:0000005)    
mean arterial blood pressure   (CMO:0000009)    
systolic blood pressure   (CMO:0000004)    
LOD Score: Not Available
P Value: 0.001
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2956,627,713 - 78,595,166RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0961,730,923 - 82,890,620RGD_MAPPER_PIPELINERnor_6.0
Rnor_5.0961,414,200 - 82,659,881RGDRnor_5.0
RGSC_v3.4953,933,135 - 76,456,066RGDRGSC_v3.4
Cross Type: intercross
Strains Crossed: SS.SHR-(D9Wox16-D9Mco85)/Mco 



Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Refined mapping of blood pressure quantitative trait loci using congenic strains developed from two genetically hypertensive rat models. Kumarasamy S, etal., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.
2. Blood pressure and proteinuria effects of multiple quantitative trait loci on rat chromosome 9 that differentiate the spontaneously hypertensive rat from the Dahl salt-sensitive rat. Toland EJ, etal., J Hypertens. 2008 Nov;26(11):2134-41.
Related QTLs

Related QTL Description Reference
Bp108 maps to same region RGD:2302803
Bp332 maps to same region RGD:2302803
Bp284 maps to same region RGD:2302803
Bp34 maps to same region RGD:2302803
Bp356 sub_region RGD:6903249
Cm28 maps to same region RGD:2302803


Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (D9Mco76)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2956,627,713 - 56,627,933 (+)MAPPER
Rnor_6.0961,730,923 - 61,731,138NCBI
Rnor_5.0961,414,200 - 61,414,415UniSTS
RGSC_v3.4953,933,135 - 53,933,350UniSTS
Celera954,109,188 - 54,109,403UniSTS
Cytogenetic Map9q31UniSTS
Peak: (D9Got111)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2990,719,946 - 90,720,113 (+)MAPPER
Rnor_6.0997,276,144 - 97,276,310NCBI
Rnor_5.0996,967,774 - 96,967,940UniSTS
RGSC_v3.4989,249,726 - 89,249,893RGD
RGSC_v3.4989,249,727 - 89,249,893UniSTS
Celera988,267,055 - 88,267,221UniSTS
RGSC_v3.1989,454,495 - 89,454,662RGD
RH 2.0 Map9927.4RGD
Cytogenetic Map9q35UniSTS
Flank 2: (D9Mco85)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2978,594,966 - 78,595,166 (+)MAPPER
Rnor_6.0982,890,421 - 82,890,620NCBI
Rnor_5.0982,659,682 - 82,659,881UniSTS
RGSC_v3.4976,455,867 - 76,456,066UniSTS
Celera976,131,308 - 76,131,507UniSTS
Cytogenetic Map9 RGD


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general measurement method: animals were on 0.3% NaCl diet, at 40-42 of age they were on 2% NaCl diet; systolic blood pressure was measured by tail-cuff method on days 24-28 of high salt regimen 2302803
qtl_general LOD of 3.57 was observed at D9Uia6 for urinary protein excretion 2302803
qtl_general number of animals used: 20 2302803