Pia27 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Pia27 (Pristane induced arthritis QTL 27) Rattus norvegicus

Symbol: Pia27
Name: Pristane induced arthritis QTL 27
RGD ID: 2302043
Previously known as: Rf1
Trait: blood immunoglobulin amount   (VT:0002460)    
Measurement Type: serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum   (CMO:0002111)    
LOD Score: 18.6
P Value: 0.001
Variance: Not Available
Inheritance Type: dominant
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21182,566,545 - 83,440,803RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01186,714,475 - 87,444,587RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01189,808,347 - 90,495,881RGDRnor5.0
RGSC_v3.41184,560,085 - 85,432,136RGDRGSC3.4
Cross Type: intercross
Strains Crossed: DA/ZtmRhd E3/ZtmRhd 



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition
pristane  (IDA)

Measurement Method

Vertebrate Trait

Rat Strain
DA/ZtmRhd  (IEA)
E3/ZtmRhd  (IEA)

References

References - curated
# Reference Title Reference Citation
1. The genetic control of rheumatoid factor production in a rat model of rheumatoid arthritis. Wernhoff P, etal., Arthritis Rheum. 2003 Dec;48(12):3584-96.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (D11Wox6)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21182,566,545 - 82,566,718 (+)MAPPER
Rnor_6.01186,714,475 - 86,714,647NCBI
Rnor_5.01189,808,347 - 89,808,519UniSTS
RGSC_v3.41184,560,085 - 84,560,257UniSTS
Celera1181,343,615 - 81,343,787UniSTS
Cytogenetic Map11q23UniSTS
Peak: (D11Wox5)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,440,555 - 83,440,803 (-)MAPPER
Rnor_6.01187,444,342 - 87,444,587NCBI
Rnor_5.01190,495,636 - 90,495,881UniSTS
RGSC_v3.41185,431,891 - 85,432,136UniSTS
Celera1182,209,127 - 82,209,372UniSTS
Cytogenetic Map11q23UniSTS
Flank 2: (D11Wox5)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,440,555 - 83,440,803 (-)MAPPER
Rnor_6.01187,444,342 - 87,444,587NCBI
Rnor_5.01190,495,636 - 90,495,881UniSTS
RGSC_v3.41185,431,891 - 85,432,136UniSTS
Celera1182,209,127 - 82,209,372UniSTS
Cytogenetic Map11q23UniSTS


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general this region has no association to rheumatoid arthritis 2302026
qtl_general measurement method: serum samples were collected on days 6, 14, 35, 49, 100, and desired levels were quantified by ELISA 2302026
qtl_general no linkage found for total levels of IgM or IgG 2302026
qtl_general inducing agent and dosage: pristane 150 microliter 2302026
qtl_general software used: Map Manager QTX software and R/qtl in R-Plus package 2302026