Bmd53 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bmd53 (Bone mineral density QTL 53) Rattus norvegicus

Symbol: Bmd53
Name: Bone mineral density QTL 53
RGD ID: 2300184
Trait: lumbar vertebra mineral mass   (VT:0010511)    
Measurement Type: volumetric bone mineral density   (CMO:0001553)    
LOD Score: 5.4
P Value: 1.0E-4
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.07100,878,730 - 143,501,887RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4798,036,672 - 143,002,779RGDRGSC3.4
Cross Type: intercross
Strains Crossed: COP/OlaHsd DA/OlaHsd 



Disease Annotations     Click to see Annotation Detail View
osteoporosis  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Vertebrate Trait

Rat Strain
COP/OlaHsd  (IEA)
DA/OlaHsd  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Linkage screen for BMD phenotypes in male and female COP and DA rat strains. Koller DL, etal., J Bone Miner Res. 2008 Sep;23(9):1382-8.
2. Epistasis between QTLs for bone density variation in Copenhagen x dark agouti F2 rats. Koller DL, etal., Mamm Genome. 2009 Jan 20.
Related QTLs

Related QTL Description Reference
Bmd56 interacts with RGD:2303105


Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Peak: (D7Rat78)
Rat AssemblyChrPosition (strand)Source
Rnor_5.07123,378,628 - 123,378,833UniSTS
RGSC_v3.47120,536,569 - 120,536,775RGD
RGSC_v3.47120,536,570 - 120,536,775UniSTS
RGSC_v3.17120,570,799 - 120,571,005RGD
Celera7109,992,435 - 109,992,640UniSTS
RH 2.0 Map7678.9RGD
SHRSP x BN Map765.7799RGD
FHH x ACI Map753.35RGD
Cytogenetic Map7q34UniSTS


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general software package: R/qtl software 2300109
qtl_general measurement method: at 26 weeks of age vertebrae wwere removed and frozen at -20oC, later slices were cut from the vertebrae and measurements taken using the XCT Research SA Plus, software version 5.40 2300109
qtl_general number of animals used: 405 males and 423 females from F2 progeny 2300109
qtl_statistics_details LOD of 4.6 was observed in females 2300109