Eae23 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Eae23 (Experimental allergic encephalomyelitis QTL 23) Rattus norvegicus

Symbol: Eae23
Name: Experimental allergic encephalomyelitis QTL 23
RGD ID: 2298495
Previously known as: Eae18a
Trait: nervous system integrity trait   (VT:0010566)    
Measurement Type: experimental autoimmune encephalomyelitis duration   (CMO:0001424)    
LOD Score: 16.93
P Value: Not Available
Variance: Not Available
Inheritance Type: additive
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21055,273,696 - 60,677,262RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01057,180,653 - 63,976,874RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01056,926,196 - 64,030,303RGDRnor5.0
RGSC_v3.41057,438,568 - 63,167,167RGDRGSC3.4
Cross Type: intercross
Strains Crossed: Kini:DA,PVG-G10 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Aipl1 is a candidate Gene for Eae23
Tekt1 is a candidate Gene for Eae23
Slc13a5 is a candidate Gene for Eae23
Pitpnm3 is a candidate Gene for Eae23
Med31 is a candidate Gene for Eae23

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Definition of a 1.06-Mb region linked to neuroinflammation in humans, rats and mice. Ockinger J, etal., Genetics. 2006 Jul;173(3):1539-45. Epub 2006 Apr 19.
Related QTLs

Related QTL Description Reference
Eae3 sub_region RGD:2293859
Eae18a sub_region RGD:2293859
Eae18 sub_region RGD:2293859


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2175Atp2a3ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3105758174257612758Rat
3350Pld2phospholipase D2105525632655274192Rat
619913Tekt1tektin 1105695216456980572Rat
70928Kif1ckinesin family member 1C105541441255444587Rat
70906Aipl1aryl hydrocarbon receptor-interacting protein-like 1105665569356664922Rat
2353Chrnecholinergic receptor nicotinic epsilon subunit105533121155339923Rat
2230C1qbpcomplement C1q binding protein105569995455704605Rat
62062Mybbp1aMYB binding protein 1a105705691357067263Rat
3240P2rx1purinergic receptor P2X 1105761858657633648Rat
621693Aspaaspartoacylase105789170457945267Rat
628841Trpv1transient receptor potential cation channel, subfamily V, member 1105785142857876513Rat
620392Ube2g1ubiquitin-conjugating enzyme E2G 1105722596357306748Rat
620256P2rx5purinergic receptor P2X 5105777773757789426Rat
621644Itgaeintegrin subunit alpha E105770481357764093Rat
620519Doc2bdouble C2 domain beta106062802960653267Rat
708476Slc25a11solute carrier family 25 member 11105535816355360278Rat
620443Myo1cmyosin 1C106049837460520752Rat
631374Slc13a5solute carrier family 13 member 5105686624956891189Rat
62000Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon106058466560622352Rat
620182Nup88nucleoporin 88105566790355692249Rat
727812Rtn4rl1reticulon 4 receptor-like 1106004324660116977Rat
1303335Ggt6gamma-glutamyl transferase 6105705202557054502Rat
2555Eno3enolase 3105537053155375921Rat
631369Serpinf1serpin family F member 1106025019860262593Rat
1304590Rap1gap2RAP1 GTPase activating protein 2105925527859472536Rat
62023Camkk1calcium/calmodulin-dependent protein kinase kinase 1105763733557660498Rat
621825Pfn1profilin 1105536526355367968Rat
1304728RGD1304728similar to 4933427D14Rik protein105678386956832668Rat
735094Srrserine racemase105976956359786688Rat
2405CrkCRK proto-oncogene, adaptor protein106053046960556703Rat
1307239Dhx33DEAH-box helicase 33105570810255724618Rat
1307527Hic1HIC ZBTB transcriptional repressor 1106001452060019475Rat
1305819Slc43a2solute carrier family 43 member 2106037546260420838Rat
620331Pafah1b1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1105953304259591808Rat
1305473Spag7sperm associated antigen 7105537724955383404Rat
1307691RilpRab interacting lysosomal protein106035527660358434Rat
1306656Inca1inhibitor of CDK, cyclin A1 interacting protein 1105540198255414364Rat
1307376Rpa1replication protein A1106014886960199999Rat
1307369Smyd4SET and MYND domain containing 4106020006760246387Rat
1306692Serpinf2serpin family F member 2106027240060280506Rat
1307222Cluhclustered mitochondria homolog105950958059531345Rat
1308683MntMAX network transcriptional repressor105969920859714848Rat
1333644Or1e23olfactory receptor family 1 subfamily E member 23105830532158315807Rat
1333892Or3a1olfactory receptor family 3 subfamily A member 1105914707559148022Rat
1332930Olr1520olfactory receptor 1520105923700359237938Rat
1332844Or1e28olfactory receptor family 1 subfamily E member 28105846875258469690Rat
1332668Olr1489-psolfactory receptor pseudogene 1489105842187558422035Rat
1333378Or1e19b-ps1olfactory receptor family 1 subfamily E member 19, pseudogene 1105819600958196513Rat
1333517Or1e27olfactory receptor family 1 subfamily E member 27105840634458407282Rat
1333146Or3a1folfactory receptor family 3 subfamily A member 1F105900005359001000Rat
1333296Or1e18b-ps1olfactory receptor family 1 subfamily E member 18, pseudogene 1105828917358290117Rat
1333088Or1e26bolfactory receptor family 1 subfamily E member 26B105834934858350286Rat
1333178Or1e35bolfactory receptor family 1 subfamily E member 35B105879721258798150Rat
1333585Or1e33olfactory receptor family 1 subfamily E member 33105861421758615152Rat
1333590Or1e16dolfactory receptor family 1 subfamily E member 16D105803624258037186Rat
1334004Olr1477-psolfactory receptor pseudogene 1477105836843958369360Rat
1334237Or3a1eolfactory receptor family 3 subfamily A member 1E105902335359024300Rat
1333952Olr1481olfactory receptor 1481105823788658238830Rat
1332685Or1a1olfactory receptor family 1 subfamily A member 1105905894159059879Rat
1311296Camta2calmodulin binding transcription activator 2105538345055401838Rat
1333627Or1e30-ps1olfactory receptor family 1 subfamily E member 30, pseudogene 1105853934058539976Rat
1332828Or1e26-ps1olfactory receptor family 1 subfamily E member 26, pseudogene 1105839491058395850Rat
1311464Fbxo39F-box protein 39105692969956934911Rat
1359186Olr1469olfactory receptor Olr1469105802506658026010Rat
1333915Or3a10-ps1olfactory receptor family 3 subfamily A member 10, pseudogene 1105895524458956190Rat
1333612Or1e27bolfactory receptor family 1 subfamily E member 27B105843438958435327Rat
1333616Or1e29-ps1olfactory receptor family 1 subfamily E member 29, pseudogene 1105857792158578858Rat
1332851Or1e20bolfactory receptor family 1 subfamily E member 20B105815180858152746Rat
1332756Or1e22olfactory receptor family 1 subfamily E member 22105817700158177939Rat
1332757Or1e31olfactory receptor family 1 subfamily E member 30105854602058546952Rat
1309457Med31mediator complex subunit 31105683694456840326Rat
1308466Ctnscystinosin, lysosomal cystine transporter105780155157817213Rat
1310602Ankrd40-ps2ankyrin repeat domain 40, pseudogene 2105591658255917772Rat
1306957Sgsm2small G protein signaling modulator 2105971818059759822Rat
1305972Rnf167ring finger protein 167105536060355364927Rat
1310963Nlrp1aNLR family, pyrin domain containing 1A105577856055833639Rat
1332804Or1p1eolfactory receptor family 1 subfamily P member 1E105909353159094502Rat
1308200Pitpnm3PITPNM family member 3105667469756766552Rat
1308139Ncbp3nuclear cap binding subunit 3105766571657695432Rat
708568Rabep1rabaptin, RAB GTPase binding effector protein 1105556615655667595Rat
1308747PimregPICALM interacting mitotic regulator105666960356674540Rat
1309330Scarf1scavenger receptor class F, member 1106035921360371516Rat
1310239Gp1baglycoprotein Ib platelet subunit alpha105535293855355804Rat
1308004Shpksedoheptulokinase105781755157841981Rat
1305467Prpf8pre-mRNA processing factor 8106033149460354606Rat
1309231Emc6ER membrane protein complex subunit 6105779407257795671Rat
1308212Wscd1WSC domain containing 1105638585856426442Rat
1332858Or1e20-ps1olfactory receptor family 1 subfamily E member 20, pseudogene 1105822292158223861Rat
1308868Txndc17thioredoxin domain containing 17105683274956835721Rat
1308924Tax1bp3Tax1 binding protein 3105779578557800363Rat
1308492RpainRPA interacting protein105569241055699910Rat
1309598Ankfy1ankyrin repeat and FYVE domain containing 1105731224657383964Rat
1333252Or1y1-ps1olfactory receptor family 1 subfamily Y member 1, pseudogene 1105879054558791005Rat
1333253Or1e1eolfactory receptor family 1 subfamily E member 1E105875443258755367Rat
1333058Or1r1olfactory receptor family 1 subfamily R member 1105889035758891301Rat
1334158Or3a1g-ps1olfactory receptor family 3 subfamily A member 1G, pseudogene 1105898225058983189Rat
1562694Dph1diphthamide biosynthesis 1106002808160039764Rat
1561884Spns3sphingolipid transporter 3105711424757169056Rat
1334253Olr1505olfactory receptor 1505105883756858838503Rat
1334012Olr1473-psolfactory receptor pseudogene 1473105810135358102121Rat
1334181Or1e32olfactory receptor family 1 subfamily E member 32105858327058584208Rat
1333989Or1e1olfactory receptor family 1 subfamily E member 1105797551957976463Rat
1549701Olr1493olfactory receptor gene Olr1493105849570958496647Rat
1359124Cyb5d2cytochrome b5 domain containing 2105739426857413336Rat
1359130Inpp5kinositol polyphosphate-5-phosphatase K106047426260495813Rat
1333845Or1d2olfactory receptor family 1 subfamily D member 2105921294759213882Rat
1333474Olr1484-psolfactory receptor pseudogene 1484105830532158305401Rat
1334013Olr1500olfactory receptor 1500105871395058714888Rat
1334190Or1e18olfactory receptor family 1 subfamily E member 18105800925258010196Rat
1334195Or3a4olfactory receptor family 3 subfamily A member 4105896724458968179Rat
1311334Wdr81WD repeat domain 81106028196960295374Rat
1333854Or1e25olfactory receptor family 1 subfamily E member 25105844633258447270Rat
1334436Or1a1bolfactory receptor family 1 subfamily A member 1B105907023959071183Rat
1334083Or1e21olfactory receptor family 1 subfamily E member 21105806991058070845Rat
1332981Olr1471olfactory receptor 1471105805734558058286Rat
1334228Or1e1colfactory receptor family 1 subfamily E member 1C105798641757987370Rat
1333482Or1p1olfactory receptor family 1 subfamily P member 1105913079659131767Rat
1311189Zzef1zinc finger ZZ-type and EF-hand domain containing 1105741326557550888Rat
1333012Or1e16olfactory receptor family 1 subfamily E member 16105827403958274983Rat
1333017Or1e21bolfactory receptor family 1 subfamily E member 21B105821468758215622Rat
1332960Olr1518-psolfactory receptor pseudogene 1518105918753959188242Rat
1563134RGD1563134similar to 60S ribosomal protein L29 (P23)105921793159218554Rat
1564837Mis12MIS12 kinetochore complex component105573959055747915Rat
1359135Mink1misshapen-like kinase 1105527829355330782Rat
1585988Xaf1XIAP associated factor 1105691728456929791Rat
1562276Ccdc92bcoiled-coil domain containing 92B105947979859501482Rat
1564623Ovca2OVCA2 serine hydrolase domain containing106002604860029211Rat
1565378Spata22spermatogenesis associated 22105794527257963081Rat
1564531Trpv3transient receptor potential cation channel, subfamily V, member 3105788354657915865Rat
1562631Tlcd2TLC domain containing 2106031057760314263Rat
1592971Or1e35olfactory receptor family 1 subfamily E member 35105877702858777966Rat
1585960Smtnl2smoothelin-like 2105700832257029505Rat
1565881Zfp3zinc finger protein 3105547842455486686Rat
61885Pitpnaphosphatidylinositol transfer protein, alpha106043071260473564Rat
1587037Rpl37-ps4ribosomal protein L37, pseudogene 4106020905660209726Rat
1593294Nlrp1bNLR family, pyrin domain containing 1B105583838155904374Rat
1593297LOC691995hypothetical protein LOC691995105575561155757162Rat
1593299ScimpSLP adaptor and CSK interacting membrane protein105550759355528288Rat
1593301Rpl36al-ps2ribosomal protein L36A, pseudogene 2105534345755343858Rat
1596210Or1e1dolfactory receptor family 1 subfamily E member 1D105886204858862983Rat
1596224Olr1468-ps1olfactory receptor 1468, pseudogene 1105865364758654541Rat
1595918Smg6SMG6 nonsense mediated mRNA decay factor105978625860014395Rat
1596207LOC687896hypothetical protein LOC687896105887515558876105Rat
1593242Mettl16methyltransferase 16, N6-methyladenosine105964091559697291Rat
1597577LOC687707hypothetical protein LOC687707105533206755333199Rat
1596276Haspinhistone H3 associated protein kinase105774773157750532Rat
1596222Or1e34olfactory receptor family 1 subfamily E member 34105866765758668595Rat
1598228Ubap2l-ps1ubiquitin-associated protein 2-like, pseudogene 1105899013158993082Rat
2303312Spns2SPNS lysolipid transporter 2, sphingosine-1-phosphate105706734857105969Rat
2322150Tsr1TSR1, ribosome maturation factor105976042059771868Rat
2323127Ly6e-ps2lymphocyte antigen 6 family member E, pseudogene 2105828770758288311Rat
2323480Ly6e-ps1lymphocyte antigen 6 family member E, pseudogene 1105801110558011735Rat
2325376Mir212microRNA 212106002340360023513Rat
2325572Mir132microRNA 132106002369660023796Rat
2325597Mir22microRNA 22106030703960307133Rat
6486589LOC100912483uncharacterized LOC100912483105684045156843674Rat
6496100Derl2derlin 2105572776455739462Rat
7489039Mir6326microRNA 6326106030678660306896Rat
7614296LOC102547395uncharacterized LOC102547395105633737456348553Rat
7650893LOC102547851uncharacterized LOC102547851105655855556622104Rat
7622441LOC102549294uncharacterized LOC102549294106065320560724367Rat
7616496Gpx4-ps2glutathione peroxidase 4, pseudogene 2106046700960467698Rat
7553451Rpl17-ps5ribosomal protein L17, pseudogene 5105729452957295230Rat
7676861LOC102548703probable serine/threonine-protein kinase drkD-like105690698356930190Rat
7699687Rps27-ps2ribosomal protein S27, pseudogene 2105743998557440286Rat
7701476LOC102547579uncharacterized LOC102547579105635448856384414Rat
9229044LOC103693362uncharacterized LOC103693362105800050358011699Rat
11405522LOC108352102chromobox protein homolog 3 pseudogene105575111555753851Rat
11486590LOC108352105uncharacterized LOC108352105105777415057777690Rat
41353991Trnat-agu17transfer RNA threonine (anticodon AGU) 17106059909960599173Rat
41204127LOC120095140uncharacterized LOC120095140106030255660304679Rat
41277263LOC120095135uncharacterized LOC120095135105643903856459676Rat
41251551LOC120095447small nucleolar RNA SNORA17105591912355919254Rat
41287325Trnas-aga18transfer RNA serine (anticodon AGA) 18105557552155575593Rat
41173355LOC120095446small nucleolar RNA SNORA17105648235456482485Rat
41328231LOC120095131uncharacterized LOC120095131105531054655317163Rat
41388596LOC120095488U2 spliceosomal RNA105963677259636857Rat
41260746LOC120095138ATP synthase subunit e, mitochondrial-like105950223859503061Rat
41330291LOC120095139uncharacterized LOC120095139106030483860309723Rat
41366645LOC120095262ATP synthase subunit g, mitochondrial-like106009245860098807Rat
41344211LOC120095437small nucleolar RNA SNORA48105746106957461206Rat
41216276LOC120095492small nucleolar RNA U3105541149055411704Rat
41196343LOC120095136uncharacterized LOC120095136105703459157041689Rat
41219691LOC120095137uncharacterized LOC120095137105719644457204660Rat
41219772LOC120095328olfactory receptor 1500-like105852657358527511Rat
41229016LOC120095327uncharacterized LOC120095327105645983556462713Rat
41293142LOC120095134uncharacterized LOC120095134105575808655765950Rat
41130072LOC120095133uncharacterized LOC120095133105554279555563841Rat
41163241LOC120095365U6 spliceosomal RNA105959581859595922Rat
41230289LOC120095497U6 spliceosomal RNA105870256458702670Rat
41351485LOC120095350U6 spliceosomal RNA106064619460646294Rat
41131756Trnap-ggg6transfer RNA proline (anticodon GGG) 6105751059057510670Rat
41352437LOC120095418U1 spliceosomal RNA105749985457500017Rat
41404273LOC120095264uncharacterized LOC120095264106007849360085842Rat
40946213LOC120095361U6 spliceosomal RNA105542206955422172Rat
40974852LOC120095377U6 spliceosomal RNA105915107859151136Rat
40999475C2h3orf33-ps1similar to human chromosome 3 open reading frame 33, pseudogene 1105633477556336418Rat
40938096LOC120095132uncharacterized LOC120095132105545827555464324Rat
40962770LOC120095370U6 spliceosomal RNA105979642959796515Rat
41008485LOC120095485U2 spliceosomal RNA106056179960561883Rat
40996527LOC120095462small nucleolar RNA SNORD91 family105976825759768349Rat
41255405LOC120095461small nucleolar RNA SNORD91 family105976896759769057Rat
41336825LOC120095261uncharacterized LOC120095261106002264760025404Rat
41020944Rpl21-ps20ribosomal protein L21, pseudogene 20105530267255303857Rat
41021825LOC120095263uncharacterized LOC120095263105974294159752455Rat
41241343Fbxo5-ps1F-box protein 5, pseudogene 1106018104060182414Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
37720D10Rat80149105937813559378278Ratregion
39588D1Rat297247105645849456458731Ratregion
39762D10Rat160205105678659656786787Ratregion
41254D10Rat159172106067708660677262Ratregion
42923D10Rat241238105770518957705411Ratregion
42370D10Rat238142106022231060222446Ratregion
41092D10Rat158200105587313655873336Ratregion
1303357D10Got165141105554920155549342Ratregion
1303359D10Got166234105844562058445852Ratregion
66490D10Mco60259105709616957096392Ratregion
1630720D10Got240204105665179656652002Ratregion
1630732D10Got227178105973294559733123Ratregion
1631253D10Wox42181105527369655273877Ratregion
1632328D10Got235147105667916656679313Ratregion
1632419D10Got233148105693451156934659Ratregion
1578974D10Chm62200105792586457926093Ratregion
1627580D10M11Mit22387105633937956339466Ratregion
1641292D10Got414200105632532056325520Ratregion
1641402D10Got412234105948803159488265Ratregion
1640581D10Got409178105718296457183138Ratregion
1635815D10M11Nds199105973300459733103Ratregion
1637892D10Got236138105786391957864057Ratregion
1638078D10Got210231105801050258010733Ratregion
1638078D10Got210231105828865758288866Ratregion
1634094D10Got247251105598916055989413Ratregion
7206026Olfr399549105896739758967946Ratregion
5035921PMC310661P1249106062116360621412Ratregion
5036155D11Bhm873105971991359719986Ratregion
7206548UniSTS:5470341463105535784955359312Ratregion
5036797AU049236272106013382360134097Ratregion
5031290PMC126639P1176105785541057855586Ratregion
5034227RH141847216105750747757507693Ratregion
5026324RH131773184105566736555667549Ratregion
5028993RH143106121105976962859769749Ratregion
5026792RH133546197105537544055375876Ratregion
5027066D17S2042211105730835657308567Ratregion
5032743RH135138206105544377455443980Ratregion
5027427AI84833292105667501756675109Ratregion
5033009RH137267198106001280960013007Ratregion
5028109Z19599172106062168760621859Ratregion
5028139D11Mit364112105685863456858746Ratregion
5025712RH129368201105953102559531226Ratregion
5033779RH140090216105567141655671632Ratregion
5033817RH140231218106049647760496695Ratregion
5056387RH144349143106058847060588613Ratregion
5051963RH94760173106062167460621847Ratregion
5057442BG375498129106065120560651334Ratregion
5055567RH143875101105969344159693542Ratregion
5058832BF387133166106013474460134910Ratregion
5058186BF386775150105976686259767012Ratregion
5049928RH133762210105566800055668811Ratregion
5050394RH134031215105537728255377495Ratregion
5049888RH133740203105665573456655937Ratregion
5050768RH134247180105953417859534358Ratregion
5051503AV32860897105536477955364876Ratregion
5050980RH134369194105776381957764013Ratregion
5044932RH130886201105953483559535036Ratregion
5045926RH131458193105763270157632894Ratregion
5041842RH129090204106002809660028300Ratregion
5044656RH130729185106027251960272704Ratregion
5047556RH1323950106030942160309629Ratregion
5049154RH133316189105738368257383871Ratregion
5046672RH131888188105566525655665444Ratregion
5046826RH131977210106036408660364296Ratregion
5048070RH132691186105540201555402201Ratregion
5046964RH132056197105572785455728051Ratregion
5049674RH133616208106000541160005619Ratregion
5049684RH133622219105667411256674331Ratregion
5047120RH132145184106011657160116755Ratregion
5039910RH127978218106025037260250833Ratregion
5048512RH132946191106014701860147209Ratregion
5039426RH127699219106055546360555682Ratregion
5042070RH129221169105569995755700126Ratregion
5042964RH129750210106055642860556638Ratregion
5039902RH127973205105787614557876350Ratregion
5042544RH129498187105570003755700224Ratregion
5040828RH128507188106052038060520568Ratregion
5040930RH128565211106062167460621885Ratregion
5039982RH128020217105570016155700560Ratregion
5042734RH129614206106052051560520721Ratregion
5043086RH129824183106062207860622261Ratregion
5041502RH128893187105667487656675063Ratregion
5074394RH137992211105574877255748983Ratregion
5076146RH139006161105570688155707042Ratregion
5075038RH138363186105927476259274948Ratregion
5077088RH139553190106042008560420807Ratregion
5077318RH139687198105787958257879780Ratregion
5077322RH139690183106041659060416773Ratregion
5076254RH139069175105567285055673025Ratregion
5079992RH141320196105968674859686944Ratregion
5080064RH141362216105570595855706174Ratregion
5073042RH137201205105780158257801787Ratregion
5073518RH137482181105670885856709039Ratregion
5073578RH137517120105535776955357889Ratregion
5073704RH137590191105548635155486542Ratregion
5073826RH137661126105950123359501359Ratregion
5070684RH134645220105784173657841956Ratregion
5072868RH137101195106047315660473351Ratregion
5070910RH134776197106062169960621896Ratregion
5070942RH134795181106002518360025364Ratregion
5073410RH137420206105683704056837246Ratregion
5072012RH135414184105660359956603783Ratregion
5071636RH135197218105574687555747093Ratregion
5071834RH135311195105721091057211105Ratregion
5063418BE107661156105746098157461137Ratregion
5069973RH94394118106055328560553403Ratregion
5066356PMC16295P1262105787615657876418Ratregion
5087414CRK319106054141360541732Ratregion
5089625AU049266133105634772556347858Ratregion
5081941BF415384135105925628659256421Ratregion
5087761D11Bhm1485105987373359873818Ratregion
5082273BE119095161106047575160475912Ratregion
5082357BE119243182105968626559686447Ratregion
5080746RH141758181106015275460152935Ratregion
5090233AU049629282105602237856022660Ratregion
5081422AI511473218106049555760495775Ratregion
5083631BE100929150106001926660019416Ratregion
5503140PRPF883106035148060352626Ratregion
5503176ksks290457105972682359727280Ratregion
5503252UniSTS:237527210105774834357748553Ratregion
5505212Serpinf2240106027750460277866Ratregion
5499541G54872248106001554160015789Ratregion
5499685G73120149105683891456839336Ratregion
5500079UniSTS:236635168105953016859530336Ratregion
5500081UniSTS:236639252105971375459714006Ratregion
5500220AI42767998105705457857054676Ratregion
5502953Sgsm2621105972302959723650Ratregion
5500621RH136313187105706696457067151Ratregion
5500651RH136477195105536461555364810Ratregion
5500887G09516148105532024555320393Ratregion
5502391RH124699145106001451860014663Ratregion
Position Markers

Flank 1: (D10Wox42)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21055,273,696 - 55,273,877 (+)MAPPER
Rnor_6.01057,180,653 - 57,180,833NCBI
Rnor_5.01056,926,196 - 56,926,376UniSTS
RGSC_v3.41057,438,568 - 57,438,748UniSTS
Celera1054,419,372 - 54,419,552UniSTS
Cytogenetic Map10q23.3-q24UniSTS
Peak: (D10Rat238)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21060,222,310 - 60,222,446 (+)MAPPER
Rnor_6.01062,213,865 - 62,214,000NCBI
Rnor_5.01061,926,964 - 61,927,099UniSTS
RGSC_v3.41062,685,555 - 62,685,691RGD
RGSC_v3.41062,685,556 - 62,685,691UniSTS
RGSC_v3.11062,699,178 - 62,699,314RGD
Celera1059,251,945 - 59,252,078UniSTS
SHRSP x BN Map1046.5699UniSTS
SHRSP x BN Map1046.5699RGD
FHH x ACI Map1050.56RGD
Cytogenetic Map10q24UniSTS
Flank 2: (D10Rat159)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21060,677,086 - 60,677,262 (+)MAPPER
Rnor_6.01063,976,699 - 63,976,874NCBI
Rnor_5.01064,030,128 - 64,030,303UniSTS
RGSC_v3.41063,166,991 - 63,167,167RGD
RGSC_v3.41063,166,992 - 63,167,167UniSTS
RGSC_v3.11063,180,614 - 63,180,790RGD
Celera1059,701,970 - 59,702,145UniSTS
SHRSP x BN Map1046.5699RGD
SHRSP x BN Map1046.5699UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102132980561345413Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102652195761345413Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102929950464155584Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103539226764155584Rat
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)103756507982565079Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)103756507982565079Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104133325886333258Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104194452678307017Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14232313287323132Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104232313287323132Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)104287676679813922Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104444169989441699Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104444169989441699Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104444169989441699Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104502965095600334Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104736947092369470Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)104944455181709989Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104944455181709989Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105112110096121100Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1051770177107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)105177294096772940Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105177461295600334Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105178628291669536Rat
1578762Toxo1Toxoplasma gondii resistance QTL 1brain integrity trait (VT:0010579)percentage of study population displaying Toxoplasma gondii brain cysts at a point in time (CMO:0002028)105220003059378278Rat
1354585Eae18aExperimental allergic encephalomyelitis QTL 18a7.50.0004nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)105379738558445852Rat
2306787Ean3Experimental allergic neuritis QTL 33.1nervous system integrity trait (VT:0010566)body weight loss (CMO:0001399)105379738566979128Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105480929299809292Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)105527369660677262Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1057134272102134272Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1057134272102134272Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1057134272102134272Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1059209888104209888Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general inducing agent: myelin oligodendrocyte glycoprotein aa1-125 2293859
qtl_general measurement method: after induction, animals were monitored and weighed daily beginning on day 7 p.i. until sacrificed 31-38 days, for changes in weight and for clinical signs of paresis/paralysis which were scored on a scale from 0-5 2293859
qtl_general number of animals used: 794 2293859
qtl_general software used: GNU R 2.0.1 with R/qtl package version 0.98-57 2293859
qtl_general allele: DA allele responsible for the additive effect of the disease 2293859
qtl_map QTL spans 1.06Mb and incorporates 13 candidate genes 2293859