Eau7 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Eau7 (Experimental allergic uveoretinitis QTL 7) Rattus norvegicus

Symbol: Eau7
Name: Experimental allergic uveoretinitis QTL 7
RGD ID: 2298480
Trait: uvea integrity trait   (VT:0010551)    
Measurement Type: experimental autoimmune uveitis score   (CMO:0001504)    
LOD Score: Not Available
P Value: 0.0049
Variance: Not Available
Inheritance Type: additive
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21027,957,626 - 34,490,668RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01035,669,573 - 36,185,929RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01035,428,387 - 35,954,931RGDRnor5.0
RGSC_v3.41035,713,561 - 36,254,741RGDRGSC3.4
Cross Type: intercross
Strains Crossed: F344/NHsd LEW/NHsd 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Csf1r is a candidate Gene for Eau7
Fabp6 is a candidate Gene for Eau7
Il3 is a candidate Gene for Eau7
Il4 is a candidate Gene for Eau7
Il5 is a candidate Gene for Eau7
Il9r is a candidate Gene for Eau7
Irf1 is a candidate Gene for Eau7
Slc22a5 is a candidate Gene for Eau7
Slc22a4 is a candidate Gene for Eau7
Il12b is a candidate Gene for Eau7
Mapk9 is a candidate Gene for Eau7
Scgb3a2 is a candidate Gene for Eau7

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
F344/NHsd  (IEA)
LEW/NHsd  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Common genetic determinants of uveitis shared with other autoimmune disorders. Mattapallil MJ, etal., J Immunol. 2008 May 15;180(10):6751-9.
Related QTLs

Related QTL Description Reference
Pia15 maps to same region RGD:2296064
Eae3 maps to same region RGD:2296064


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2054Adra1badrenoceptor alpha 1B102825502528373418Rat
708470Ifi47interferon gamma inducible protein 47103329761833305248Rat
628704Il12binterleukin 12B102888883228903802Rat
69229Rack1receptor for activated C kinase 1103316941533174896Rat
620097Mgat1alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase103356364233582718Rat
735025Or2y13olfactory receptor family 2 subfamily Y member 13103378883233789767Rat
621737Flt4Fms related receptor tyrosine kinase 4103391372533954770Rat
628847Mapk9mitogen-activated protein kinase 9103416966134211138Rat
620953Ebf1EBF transcription factor 1102909585829489142Rat
727901Scgb3a1secretoglobin, family 3A, member 1103396805933969366Rat
1303328Clint1clathrin interactor 1103029861830353185Rat
1303097Gfpt2glutamine-fructose-6-phosphate transaminase 2103411500534161329Rat
1307328Trim7tripartite motif-containing 7103320549133221482Rat
1305048Cyfip2cytoplasmic FMR1 interacting protein 2103062131830741113Rat
1305163Irgmimmunity-related GTPase M103323351333241594Rat
1306638Sgcdsarcoglycan, delta103134648032328364Rat
708425Havcr1hepatitis A virus cellular receptor 1103111866731151730Rat
1333284Or2y17-ps1olfactory receptor family 2 subfamily Y member 17, pseudogene 1103363807633639211Rat
1333402Or2y1golfactory receptor family 2 subfamily Y member 1G103359878833599723Rat
1333419Or2y15olfactory receptor family 2 subfamily Y member 15103370729133708226Rat
1333927Olr1400olfactory receptor 1400103381634533817280Rat
1311549Rasgef1cRasGEF domain family, member 1C103422748334293676Rat
1333100Or2y1holfactory receptor family 2 subfamily Y member 1H103360951133610446Rat
1310783Cnot6CCR4-NOT transcription complex, subunit 6103397878534031025Rat
1333571Or2y1colfactory receptor family 2 subfamily Y member 1C103371783133718760Rat
1332806Or2y11olfactory receptor family 2 subfamily Y member 11103384475833845693Rat
1309561Rnf145ring finger protein 145102900639129050788Rat
1310147Tbc1d9bTBC1 domain family member 9B103445993034497146Rat
1305233Havcr2hepatitis A virus cellular receptor 2103088248430914018Rat
1305891Pwwp2aPWWP domain containing 2A102815550928195255Rat
1311618ItkIL2-inducible T-cell kinase103075334430814685Rat
1309452Nipal4NIPA-like domain containing 4103058392630600640Rat
1333440Or2y1olfactory receptor family 2 subfamily Y member 1103374878133759730Rat
1308885Trim41tripartite motif-containing 41103317521333186472Rat
1332792Or2y1eolfactory receptor family 2 subfamily Y member 1E103362385933624794Rat
1310386Ublcp1ubiquitin-like domain containing CTD phosphatase 1102894569028961103Rat
1561384Ccnjlcyclin J-like102799568228053428Rat
1560464Fam98b-ps1family with sequence similarity 98, member B, pseudogene 1103333639133338220Rat
1334353Or2v1olfactory receptor family 2 subfamily V member 1103339989133404298Rat
1564516Timd4T-cell immunoglobulin and mucin domain containing 4103118575131221843Rat
1561041C1qtnf2C1q and TNF related 2102794194827958926Rat
1334152Or2y1dolfactory receptor family 2 subfamily Y member 1D103367649733677426Rat
1332722Or2y16olfactory receptor family 2 subfamily Y member 16103369047933691414Rat
1559575RGD1559575similar to novel protein103325214633276364Rat
1359513Thg1ltRNA-histidine guanylyltransferase 1-like103038792930396579Rat
1334139Or2y14olfactory receptor family 2 subfamily Y member 14103374889833772292Rat
1333858Or2y1iolfactory receptor family 2 subfamily Y member 1I103373719933738128Rat
1562041Rnf130ring finger protein 130103434283534456048Rat
1333024Or2v2bolfactory receptor family 2 subfamily V member 2B103337986333380810Rat
1333732Or2y12olfactory receptor family 2 subfamily Y member 12103380072033801655Rat
1359571Timd2T-cell immunoglobulin and mucin domain containing 2103106030831101262Rat
1333300Or2v2colfactory receptor family 2 subfamily V member 2C103331984433320791Rat
1586382Sox30SRY-box transcription factor 30103041749930446441Rat
1586044Or2v2olfactory receptor family 2 subfamily V member 2103335195433352895Rat
1359604Ttc1tetratricopeptide repeat domain 1102820232528227464Rat
1565523Lsm11LSM11, U7 small nuclear RNA associated103036784130385956Rat
1582887Wbp11-ps7WW domain binding protein 11, pseudogene 7103338302133384950Rat
1562355Atp6v1g1l1ATPase H+ transporting V1 subunit G1 like 1102866397428664273Rat
1560191Zfp62zinc finger protein 62103352261833539446Rat
1563555Garin3golgi associated RAB2B interactor family member 3103082987730833115Rat
1584011Wbp11-ps6WW domain binding protein 11, pseudogene 6103332301233325107Rat
1586325Dppa1developmental pluripotency associated 1103099804931017756Rat
1590287Btnl9butyrophilin-like 9103346605933489229Rat
1585017Adam19ADAM metallopeptidase domain 19103049136230583115Rat
1585207Surf6-ps2surfeit 6, pseudogene 2103117475631176633Rat
2592Fabp6fatty acid binding protein 6102806360328068276Rat
1589910Rps2-ps35ribosomal protein S2, pseudogene 35102814493228146035Rat
1589937Atp5if1-ps2ATP synthase inhibitory factor subunit 1, pseudogene 2102811183328112277Rat
1584858Gins4-ps1GINS complex subunit 4, pseudogene 1102893193928933904Rat
1590296Or2m13olfactory receptor family 2 subfamily M member 13103346033733461275Rat
1589570Or2t26olfactory receptor family 2 subfamily T member 26103344654033447493Rat
1586332Havcr1l2hepatitis A virus cellular receptor 1 like 2103096305830983169Rat
2318580Fndc9fibronectin type III domain containing 9103066443530668213Rat
2319448Hax1-ps2HCLS1 associated protein X-1, pseudogene 2103132788831329144Rat
2322743Hars2l1histidyl-tRNA synthetase 2 like 1103313993633141734Rat
2322151Eif3i-ps3eukaryotic translation initiation factor 3, subunit I, pseudogene 3103364790133648990Rat
2322885Rpl30-ps1ribosomal protein L30, pseudogene 1103312940633130617Rat
2322499Rpl31l2ribosomal protein L31-like 2103337529633375771Rat
2322651Wbp11-ps8WW domain binding protein 11, pseudogene 8103335512933358199Rat
2323463Havcr1l1hepatitis A virus cellular receptor 1 like 1103091986030941388Rat
2325403Mir336microRNA 336103418557934185674Rat
6494481Med7mediator complex subunit 7103084233030857873Rat
7522823LOC102557028uncharacterized LOC102557028103328644133303560Rat
7523136LOC102550019uncharacterized LOC102550019102882108428887949Rat
7561849LOC102555091nuclear envelope pore membrane protein POM 121-like103389166933895263Rat
7566942Kmt5a-ps2lysine methyltransferase 5A, pseudogene 2103108663031088837Rat
7714490LOC102549660uncharacterized LOC102549660102864248628659252Rat
7679467LOC102550742uncharacterized LOC102550742103014121030271461Rat
7729046LOC10255524360S ribosomal protein L29-like103409563134096185Rat
9339380LOC103693316activated RNA polymerase II transcriptional coactivator p15 pseudogene103047357630474470Rat
11471077Trnat-ugu1transfer RNA threonine (anticodon UGU) 1103322265233222724Rat
11369295LOC10835207560S ribosomal protein L34 pseudogene102810055028100901Rat
11364143Trnav-aac5transfer RNA valine (anticodon AAC) 5103322579033225862Rat
11412952LOC108352076uncharacterized LOC108352076102827573428366956Rat
11421503LOC10835221760S ribosomal protein L17 pseudogene103312479133125414Rat
11359066Cnot6l2CCR4-NOT transcription complex, subunit 6 like 2103401895434026932Rat
11427237Trnav-aac4transfer RNA valine (anticodon AAC) 4103319402233194094Rat
11427364Trnak-cuu16transfer RNA lysine (anticodon CUU) 16103320179133201863Rat
11396808LOC108352074uncharacterized LOC108352074102797451527983092Rat
11385134Trnal-aag3transfer RNA leucine (anticodon AAG) 3103322615833226239Rat
11388507Trnap-ugg5transfer RNA proline (anticodon UGG) 5103322542333225494Rat
11411642Trnaa-ugc2transfer RNA alanine (anticodon UGC) 2103320227233202343Rat
11519998Trnav-cac2transfer RNA valine (anticodon CAC) 2103318752533187597Rat
11485485LOC108352079uncharacterized LOC108352079102864501128668249Rat
11492721LOC108352081heterogeneous nuclear ribonucleoprotein A3 pseudogene103323587833236925Rat
14398588Mir340-1microRNA 340-1103439356834393665Rat
41112529LOC120095394small nucleolar RNA SNORD95103316993733170004Rat
41087638LOC120095089uncharacterized LOC120095089103420780234218525Rat
41381590LOC120095084uncharacterized LOC120095084103325431633263503Rat
41327896LOC120095506U6 spliceosomal RNA103320397733204083Rat
41362314Snord95small nucleolar RNA, C/D box 95103317198333172050Rat
41210406LOC120095353U6 spliceosomal RNA103096411730964223Rat
41329759LOC120095077uncharacterized LOC120095077102898597428988675Rat
41095314LOC120095081uncharacterized LOC120095081102908747829094518Rat
41331781LOC120095075uncharacterized LOC120095075102875381828755862Rat
41268997Snord96asmall nucleolar RNA, C/D box 96A103317109333171172Rat
41103944LOC120095085uncharacterized LOC120095085103347104833479197Rat
41159125Nop16-ps3NOP16 nucleolar protein, pseudogene 3102883471928835165Rat
41229905LOC120095080uncharacterized LOC120095080102915132529174781Rat
41271983LOC120095082uncharacterized LOC120095082103021597930229712Rat
41108829Trnap-agg70transfer RNA proline (anticodon AGG) 70102809977528099855Rat
41352852LOC120095086uncharacterized LOC120095086103355644633563549Rat
40971431LOC120095083uncharacterized LOC120095083103049211630495725Rat
41013984LOC120095079uncharacterized LOC120095079102937281729379810Rat
40984111LOC120095448small nucleolar RNA SNORA17103008879130088922Rat
40936152LOC120095088uncharacterized LOC120095088103411404234116357Rat
40988783Zfp622-ps1zinc finger protein 622, pseudogene 1103288404232885277Rat
41247591LOC120095500U6 spliceosomal RNA103048549930485605Rat
41337377LOC120095453small nucleolar RNA SNORA17103306016033060278Rat
41302965LOC120095078uncharacterized LOC120095078102905821329075530Rat
41235583LOC120095087uncharacterized LOC120095087103403766334063640Rat
41019890LOC120095318uncharacterized LOC120095318102868818128689960Rat
41073392LOC120095475U1 spliceosomal RNA103225253132252689Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
34359D10Mgh11138102929950429299638Ratregion
34677D10Mgh19100103063149230631600Ratregion
33565D10Mit9238103122402631224268Ratregion
35571D10Rat35147103167468831674835Ratregion
36067D10Rat38170103096480030964974Ratregion
37454D10Rat82192103222339032223584Ratregion
36496D10Rat37179103397392133974100Ratregion
36721D10Rat40184102898094628981111Ratregion
35040D10Rat39170102962646529626644Ratregion
38162D10Rat129211103389769133897901Ratregion
39102D10Rat71201102887565028875843Ratregion
42908D10Rat253135102930956729309696Ratregion
42910D10Rat250213103351360133513811Ratregion
41732D10Rat224148103252655932526706Ratregion
44714D10Got44135102906082629060961Ratregion
44715D10Wox26170102965946229659617Ratregion
44716D10Got50211103049313930493350Ratregion
44717D10Got45199102857817828578377Ratregion
44718D10Got47210103010782530108035Ratregion
44719D10Got51146103034131630341462Ratregion
44724D10Got53202103091925930919461Ratregion
44725D10Got48141102875455228754693Ratregion
44727D10Got52118103127302631273141Ratregion
44728D10Got54282103251301832513300Ratregion
625797D10Got46118102968858029688698Ratregion
625798D10Got49233103061251830612748Ratregion
61279D10Arb3109103449055934490668Ratregion
66463D10Mco53260102912499629125903Ratregion
1630911D10Got232169103396097933961148Ratregion
1640308D10Got411222103098037730980599Ratregion
7193065D5S412115102940835729408472Ratregion
5039240RH127592215103085761330857828Ratregion
5028729RH47813177103231460432314781Ratregion
5031814AU047063187103236595632366145Ratregion
5031848AU046953149103174866831748817Ratregion
5027032RH134471184103330504833305231Ratregion
5035378BM386620158102819045428190616Ratregion
5027171D5S412163102940835729408520Ratregion
5032687RH134927156102805326428053420Ratregion
5027419AW45644288103397950033979588Ratregion
5030399BI294827186102822553928225725Ratregion
5030521BF40365999103440103734401136Ratregion
5028125D11Mit175106102910210929102215Ratregion
5056355RH144330189103063906730639256Ratregion
5057878BF392858237103356897833569215Ratregion
5052496AI431060226103058280630583032Ratregion
5054657RH143350167103135020231350369Ratregion
5051076RH134426212103035263930352851Ratregion
5045158RH131017182103323368333233865Ratregion
5048722RH133067186103038792930388115Ratregion
5044876RH130854197103317530633175503Ratregion
5047522RH132376210102820243628202646Ratregion
5049438RH133481209102921066329210872Ratregion
5049476RH133503197102825505728255254Ratregion
5049486RH133509191103445570134455892Ratregion
5048294RH132820182103058444630584628Ratregion
5049790RH133683203103397901533979218Ratregion
5039634RH127818187102948796929488156Ratregion
5039850RH127943220103317317033174731Ratregion
5040216RH128156212103058282030583032Ratregion
5041398RH128834208102894576428945972Ratregion
5041504RH128894199103057776130577960Ratregion
5072324RH136783187103037081530371002Ratregion
5076464RH139190120102820243628202556Ratregion
5077818RH139977199103396891833969468Ratregion
5077446RH139761203102898680428988339Ratregion
5078328RH140277220103062144130621661Ratregion
5078646RH140465109103106054931060658Ratregion
5074456RH138027121103448520634485327Ratregion
5074774RH138211188103355648533556673Ratregion
5071896RH135347219103447778134478000Ratregion
5066684AU048212122103324339533243517Ratregion
5067268AU047858242102857291528573157Ratregion
5067772AU047545143102800581028005953Ratregion
5068262AU047252124103076138730761513Ratregion
5070378AI64203693103035280530352898Ratregion
5069786AU028693174103324493433245108Ratregion
5063658BE107925170102928305929283229Ratregion
5066192BF407519165102914999929150164Ratregion
5063016BF410193113103056838630568499Ratregion
5061540BF396659221103117458931174867Ratregion
5086973BM386911202102909551929095721Ratregion
5086056AW529436157103421278934212946Ratregion
5088961AU048871159102820901228209173Ratregion
5088961AU048871159102820901228209335Ratregion
5083389BF391033157102849724828497405Ratregion
5089667AU049292279103054695230547231Ratregion
5084748AI102757130103223501932235149Ratregion
5080794RH141785205103035204630352251Ratregion
5081068RH141946205103117465731174867Ratregion
5085523BQ203079154103113252931132683Ratregion
5089141AU048979275103340646633406739Ratregion
5081272RH142065204103402671034026914Ratregion
5504676PMC355839P4217102888864528888862Ratregion
5504674PMC355839P1734102889665628897391Ratregion
5505592UniSTS:485100936103380071933801655Ratregion
5506855G46608165103061257830612743Ratregion
5499517stSG6106050103025484130256125Ratregion
5500258D3S3187982102945838829459370Ratregion
5500073UniSTS:236559355102818039028180745Ratregion
5500953MARC_9845-9846:996688657:10103032612030326760Ratregion
5501295D11S2605145103300074833000893Ratregion
5502752SOX3098103042119530421293Ratregion
550279721STS02197103062132230621519Ratregion
Position Markers

Flank 1: (D10Mgh10)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01036,185,929 - 36,186,066NCBI
Rnor_5.01035,954,931 - 35,955,068UniSTS
RGSC_v3.41036,254,742 - 36,254,879UniSTS
RGSC_v3.41036,254,741 - 36,254,879RGD
RGSC_v3.11036,255,791 - 36,255,928RGD
Celera1034,362,292 - 34,362,429UniSTS
RH 3.4 Map10374.6UniSTS
RH 3.4 Map10374.6RGD
RH 2.0 Map10401.0RGD
SHRSP x BN Map1034.04RGD
FHH x ACI Map1033.0199RGD
Cytogenetic Map10q22UniSTS
Peak: (D10Mit9)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21031,224,026 - 31,224,268 (+)MAPPER
Rnor_6.01031,919,397 - 31,919,634NCBI
Rnor_5.01031,740,635 - 31,740,872UniSTS
RGSC_v3.41031,931,622 - 31,931,860RGD
RGSC_v3.41031,931,623 - 31,931,860UniSTS
RGSC_v3.11031,932,672 - 31,932,909RGD
Celera1030,668,756 - 30,668,993UniSTS
RH 3.4 Map10340.71UniSTS
RH 3.4 Map10340.71RGD
RH 2.0 Map10373.7RGD
Cytogenetic Map10 RGD
Flank 2: (D10Arb3)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21034,490,559 - 34,490,668 (+)MAPPER
Rnor_6.01035,669,465 - 35,669,573NCBI
Rnor_5.01035,428,279 - 35,428,387UniSTS
RGSC_v3.41035,713,452 - 35,713,561RGD
RGSC_v3.41035,713,453 - 35,713,561UniSTS
RGSC_v3.11035,714,501 - 35,714,610RGD
Celera1033,839,800 - 33,839,908UniSTS
Cytogenetic Map10q22UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101790711351786432Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102132980561345413Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
631531Iresp2Immunoglobin response QTL26.3blood immunoglobulin E amount (VT:0002492)serum total immunoglobulin E level (CMO:0001542)102291826836400810Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102652195761345413Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2298480Eau7Experimental allergic uveoretinitis QTL 70.0049uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)102795762634490668Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102887565052200160Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102929950464155584Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103449055945579777Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general allele: decreased susceptibility observed in animals homozygous for F allele and animals homozygous for L allele showed increased susceptibility 2296064
qtl_general inducing agent: 30 micrograms of peptide R16, major uveitogenic epitope of bovine IRBP 2296064
qtl_general number of animals used: 1287 2296064
qtl_general allele: LEW allele was responsible for higher incidence of disease 2296064
qtl_general measurement method: after 16-18 days of immunization, eyes were collected and evaluated histopathologically by scoring 0-4, average score of both the eyes taken 2296064