Bss48 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bss48 (Bone structure and strength QTL 48) Rattus norvegicus

Symbol: Bss48
Name: Bone structure and strength QTL 48
RGD ID: 2293703
Trait: lumbar vertebra size trait   (VT:0010518)    
Measurement Type: lumbar vertebra trabecular cross-sectional area   (CMO:0001692)    
LOD Score: 16.05
P Value: 1.0E-4
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.07100,878,730 - 143,501,887RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4798,036,672 - 143,002,779RGDRGSC3.4
Cross Type: intercross
Strains Crossed: COP/OlaHsd DA/OlaHsd 



Disease Annotations     Click to see Annotation Detail View
osteoporosis  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Vertebrate Trait

Rat Strain
COP/OlaHsd  (IEA)
DA/OlaHsd  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Genetic loci affecting bone structure and strength in inbred COP and DA rats. Sun Q, etal., Bone. 2008 Mar;42(3):547-53. Epub 2007 Nov 28.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Peak: (D7Rat78)
Rat AssemblyChrPosition (strand)Source
Rnor_5.07123,378,628 - 123,378,833UniSTS
RGSC_v3.47120,536,569 - 120,536,775RGD
RGSC_v3.47120,536,570 - 120,536,775UniSTS
RGSC_v3.17120,570,799 - 120,571,005RGD
Celera7109,992,435 - 109,992,640UniSTS
RH 2.0 Map7678.9RGD
SHRSP x BN Map765.7799RGD
FHH x ACI Map753.35RGD
Cytogenetic Map7q34UniSTS


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general number of animals used: 405 males and 423 females from F2 progeny 2293455
qtl_general measurement method: at 26 weeks of age lumbar 5 vertebrae was removed and frozen at -20oC, later slices were cut from lumbar spine and neural arch and measurements taken from pQCT images 2293455
qtl_general software package: MAPMAKER/EXP 2293455
qtl_general allele: DA alleles cause stronger skeletal structure and strength 2293455
qtl_statistics_details LOD of 9.79 was recorded for males and LOD of 7.59 for females 2293455