Stl20 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Stl20 (Serum triglyceride level QTL 20) Rattus norvegicus

Symbol: Stl20
Name: Serum triglyceride level QTL 20
RGD ID: 1582229
Previously known as: TG (dex, ln)
Trait: blood triglyceride amount   (VT:0002644)    
Measurement Type: serum triglyceride level   (CMO:0000360)    
LOD Score: 3.2
P Value: 0.0033
Variance: 14.0
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2848,630,131 - 49,147,989RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0852,644,745 - 53,117,620RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0851,241,951 - 51,710,641RGDRnor5.0
RGSC_v3.4851,577,566 - 52,065,790RGDRGSC3.4
RGSC_v3.1851,596,621 - 52,084,844RGD
Cross Type: intercross
Strains Crossed: PD/Cub BN/Cub 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
BN/Cub  (IEA)
PD/Cub  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Dynamic genetic architecture of metabolic syndrome attributes in the rat. Seda O, etal., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
727921Zbtb16zinc finger and BTB domain containing 1684898937649177011Rat
1304874Rexo2RNA exonuclease 284881190048823622Rat
1308017Rbm7RNA binding motif protein 784883189448838399Rat
1309606Nnmtnicotinamide N-methyltransferase84892866348947734Rat
1563941C8h11orf71similar to human chromosome 11 open reading frame 7184883855648838970Rat
1560781Nxpe4neurexophilin and PC-esterase domain family member 484850269748744101Rat
1566243Nxpe1neurexophilin and PC-esterase domain family, member 184874925048773762Rat
2323193Nxpe2neurexophilin and PC-esterase domain family, member 284866170848695555Rat
41362515LOC120094143uncharacterized LOC12009414384893598248941209Rat
41160523LOC120094141uncharacterized LOC12009414184869727848697867Rat
41199271LOC120094144uncharacterized LOC12009414484909029449092983Rat
41152571LOC120094140uncharacterized LOC12009414084872258448730793Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
36872D8Rat4311284863013148630243Ratregion
42467D1Rat40523884903006949030308Ratregion
44411D8Got7217784914781249147989Ratregion
1638505D8Got35517184879556248795733Ratregion
7206404mMaCIR130157784908896749090544Ratregion
5028881RH14268112984866181848661947Ratregion
5030889BF41118011684870872148708837Ratregion
5053897RH14291410184898977048989871Ratregion
5052589RH12573324984870623948706488Ratregion
5046344RH13169818184883939548839576Ratregion
5048390RH13287618884877347348773661Ratregion
5048510RH13294518184883264148832822Ratregion
5043658RH13015219484881204748812241Ratregion
5073936RH13772420884872850448728712Ratregion
5075778RH13879123784899193748992175Ratregion
5076334RH13911512784870736848707495Ratregion
5065732BF40631315984893907448939233Ratregion
5087090BE10699918584910192049102105Ratregion
5087325BQ19390319684892893148929127Ratregion
5089913AU04943813384868248348682616Ratregion
5089925AU04944518684894185548942041Ratregion
5082049BF40920014184875604148756182Ratregion
Position Markers

Flank 1: (D8Rat43)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2848,630,131 - 48,630,243 (+)MAPPER
Rnor_6.0852,644,745 - 52,644,856NCBI
Rnor_5.0851,241,951 - 51,242,062UniSTS
RGSC_v3.4851,577,566 - 51,577,678RGD
RGSC_v3.4851,577,567 - 51,577,678UniSTS
RGSC_v3.1851,596,621 - 51,596,732RGD
Celera848,191,252 - 48,191,363UniSTS
RH 3.4 Map8507.0UniSTS
RH 3.4 Map8507.0RGD
RH 2.0 Map8378.2RGD
SHRSP x BN Map836.87RGD
FHH x ACI Map843.6199RGD
Peak: (D8Rat43)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2848,630,131 - 48,630,243 (+)MAPPER
Rnor_6.0852,644,745 - 52,644,856NCBI
Rnor_5.0851,241,951 - 51,242,062UniSTS
RGSC_v3.4851,577,566 - 51,577,678RGD
RGSC_v3.4851,577,567 - 51,577,678UniSTS
RGSC_v3.1851,596,621 - 51,596,732RGD
Celera848,191,252 - 48,191,363UniSTS
RH 3.4 Map8507.0UniSTS
RH 3.4 Map8507.0RGD
RH 2.0 Map8378.2RGD
SHRSP x BN Map836.87RGD
FHH x ACI Map843.6199RGD
Flank 2: (D8Got72)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2849,147,812 - 49,147,989 (+)MAPPER
Rnor_6.0853,117,444 - 53,117,620NCBI
Rnor_5.0851,710,465 - 51,710,641UniSTS
RGSC_v3.4852,065,613 - 52,065,790RGD
RGSC_v3.4852,065,614 - 52,065,790UniSTS
RGSC_v3.1852,084,668 - 52,084,844RGD
Celera848,704,993 - 48,705,171UniSTS
RH 3.4 Map8535.2UniSTS
RH 3.4 Map8535.2RGD
RH 2.0 Map8394.8RGD
Cytogenetic Map8q23UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8470581049705810Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)8768895552688955Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)8873663553736635Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82266233067662330Rat
2303564Gluco43Glucose level QTL 433blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82613018771130187Rat
2303572Insul13Insulin level QTL 132blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)82613018771130187Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)82720571554998217Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)82824291253961020Rat
1300146Rf17Renal function QTL 172.9renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)82824291273242912Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
2302278Gluco36Glucose level QTL 364.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82950266550095447Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)82950266570386295Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
1331744Bp217Blood pressure QTL 2173.398arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815458482492Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83084815482460899Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83084815482460899Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83084815482460899Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83084815482460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83555193880551938Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84071306682925667Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84071306693965294Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)84186687675097878Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
631216Stl9Serum triglyceride level QTL 94.710.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)84186701070386132Rat
5684993Bmd84Bone mineral density QTL 844.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)84269268450095447Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088624Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)84653172299083736Rat
1582229Stl20Serum triglyceride level QTL 203.20.0033blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)84863013149147989Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general dexamethasone (DEX) was given in drinking water (0.026mg/ml) for 3 days and triglyceride level was assessed with Triglycerides Liquicolor 1580752
qtl_statistics_details specific pairs of variables were compared by one or two way ANOVA with post hoc Tukey's honest significance difference test; linkage analysis was done on logarithm-transformed values 1580752