Gluco19 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Gluco19 (Glucose level QTL 19) Rattus norvegicus

Symbol: Gluco19
Name: Glucose level QTL 19
RGD ID: 1582203
Previously known as: Glucose (sucrose diet, 0min)
Trait: blood glucose amount   (VT:0000188)    
Measurement Type: blood glucose level   (CMO:0000046)    
LOD Score: 3.3
P Value: 0.001
Variance: 15.0
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2992,491,589 - 100,929,786RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0999,041,068 - 107,878,528RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0998,715,385 - 107,462,796RGDRnor5.0
RGSC_v3.4991,131,330 - 99,799,902RGDRGSC3.4
RGSC_v3.1991,336,305 - 100,009,382RGD
Cross Type: intercross
Strains Crossed: PD/Cub BN/Cub 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
BN/Cub  (IEA)
PD/Cub  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Dynamic genetic architecture of metabolic syndrome attributes in the rat. Seda O, etal., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22.
Related QTLs

Related QTL Description Reference
Bw64 interacts with RGD:1580752


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
61853Gpc1glypican 199339623493424047Rat
3252Pampeptidylglycine alpha-amidating monooxygenase99799858198271966Rat
2073Agxtalanine--glyoxylate aminotransferase99367538493685337Rat
70984BokBCL2 family apoptosis regulator BOK99422349394234476Rat
620056Septin2septin 299401814194051386Rat
708431Slco6c1solute carrier organic anion transporter family, member 6c199750002897580776Rat
619979Hdac4histone deacetylase 499250346792750164Rat
727968Ndufa10NADH:ubiquinone oxidoreductase subunit A1099300703493041825Rat
620962Hdlbphigh density lipoprotein binding protein99394809994018040Rat
621845St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 499599415096084617Rat
69354Capn10calpain 1099349813293510494Rat
1304996Kif1akinesin family member 1A99356303393647412Rat
1307449Gin1gypsy retrotransposon integrase 199829359698315155Rat
1307976D2hgdhD-2-hydroxyglutarate dehydrogenase99435055594368384Rat
1309973Fam174afamily with sequence similarity 174, member A99574281595761083Rat
708465Otosotospiralin99321694893220614Rat
1308003Farp2FERM, ARH/RhoGEF and pleckstrin domain protein 299405365094162212Rat
727809Stk25serine/threonine kinase 2599416183494174095Rat
620278Slco6b1solute carrier organic anion transporter family member 6B199726665597347336Rat
1308624Neu4neuraminidase 499439692094402576Rat
1333294Or9s23bolfactory receptor family 9 subfamily S member 23B99311732893118299Rat
1302987Ano7anoctamin 799391752493945323Rat
1333345Or9s23olfactory receptor family 9 subfamily S member 2399313148393132454Rat
1333489Or9s15olfactory receptor family 9 subfamily S member 1599314957393150544Rat
1359388Slco6d1solute carrier organic anion transporter family, member 6d199758309397739994Rat
1333615Or9s27olfactory receptor family 9 subfamily S member 2799313663293146531Rat
1307908Ing5inhibitor of growth family, member 599432691994344220Rat
1311658Pdcd1programmed cell death 199441878694431945Rat
1310902Nudt12nudix hydrolase 1299874162798755039Rat
1308169Ppp1r7protein phosphatase 1, regulatory subunit 799388606893909991Rat
1309404Gpr35G protein-coupled receptor 3599352669193539302Rat
1309614Dtymkdeoxythymidylate kinase99431555294324386Rat
1309819Chchd2l3coiled-coil-helix-coiled-coil-helix domain containing protein 2-like 399450043994501110Rat
1309819Chchd2l3coiled-coil-helix-coiled-coil-helix domain containing protein 2-like 399450062994501122Rat
1309664Atg4bautophagy related 4B, cysteine peptidase99428241794314109Rat
1306146PaskPAS domain containing serine/threonine kinase99384427593886036Rat
1562440Mterf4mitochondrial transcription termination factor 499383416293838838Rat
1563692Mab21l4mab-21 like 499369045593701267Rat
1333070Or9s14olfactory receptor family 9 subfamily S member 1499317336093174328Rat
1564730RGD1564730similar to ribosomal protein L3699281561392816212Rat
1303048Slco4c1solute carrier organic anion transporter family, member 4C199718016297229135Rat
1560925Pdzph1PDZ and pleckstrin homology domains 199859122298717920Rat
1332746Or6b2olfactory receptor family 6 subfamily B member 299304847593049413Rat
1359473Thap4THAP domain containing 499424258194282312Rat
1333848Or9s13olfactory receptor family 9 subfamily S member 1399318459493194689Rat
1334141Or6b3olfactory receptor family 6 subfamily B member 399307003193070969Rat
1559955RGD1559955similar to 40S ribosomal protein S1799909327299093890Rat
1333485Or9s14bolfactory receptor family 9 subfamily S member 14B99316024893161207Rat
1562136Macirmacrophage immunometabolism regulator99842076098440818Rat
1334214Or6b2bolfactory receptor family 6 subfamily B member 2B99305674093057675Rat
1333005Olr1348-psolfactory receptor pseudogene 134899313324693133449Rat
1566079Sned1sushi, nidogen and EGF-like domains 199377408793834003Rat
1562727Aqp12aaquaporin 12A99355452793560011Rat
1593854Gal3st2galactose-3-O-sulfotransferase 299438245694387990Rat
1590765Ppip5k2diphosphoinositol pentakisphosphate kinase 299831528098394537Rat
1593789Noc3l-ps2NOC3-like DNA replication regulator, pseudogene 299461937094650913Rat
1589682Tpt1-ps6tumor protein, translationally-controlled 1 pseudogene 699787450697875077Rat
1585470Bmpr1a-ps1bone morphogenetic protein receptor type 1A, pseudogene 19100602229100605006Rat
1595220Dusp28dual specificity phosphatase 2899347249293474207Rat
1595229Ankmy1ankyrin repeat and MYND domain containing 199342366493476651Rat
1592616Ahcy-ps2adenosylhomocysteinase, pseudogene 299489069494892294Rat
1595210Rnpepl1arginyl aminopeptidase like 199347660093486331Rat
1590183Slco6c1l-ps1solute carrier organic anion transporter family member 6c1 like, pseudogene 199740938897461111Rat
1596701Cops9COP9 signalosome subunit 999320984393214774Rat
1592645Zfp207-ps1zinc finger protein 207, pseudogene 199471618294759721Rat
2324563LOC100362040Ac2-143-like99405057794092832Rat
6490130Set-ps2Set nuclear proto-oncogene, pseudogene 299452574394574248Rat
7656325LOC102549694protein NYNRIN-like99387646993885044Rat
7610058LOC102553020uncharacterized LOC10255302099722913997261503Rat
7727178LOC102552654uncharacterized LOC10255265499640731196442600Rat
7740505LOC102547414zinc finger protein 120-like99546270695463751Rat
7728853Crocc2ciliary rootlet coiled-coil, rootletin family member 299370878693769617Rat
9112007LOC103690574ubiquitin-associated domain-containing protein 1 pseudogene99384071293842719Rat
9384454LOC10369058740S ribosomal protein S25 pseudogene99565867595659046Rat
9685085Mir149microRNA 14999341438993414477Rat
11362438LOC108352035uncharacterized LOC10835203599893282698940487Rat
11405256LOC108351976uncharacterized LOC10835197699885796198904468Rat
11417562LOC108352034uncharacterized LOC10835203499421687394217837Rat
11410190LOC108351974uncharacterized LOC10835197499281772392865423Rat
11502495LOC108351978uncharacterized LOC10835197899844709698454842Rat
41281036LOC120094755uncharacterized LOC1200947559100320816100337741Rat
41176099LOC120094749uncharacterized LOC12009474999369094793696037Rat
41266143LOC1200949515S ribosomal RNA99415679494156912Rat
41395183LOC120094750uncharacterized LOC12009475099581984395825054Rat
41348918LOC120094939small nucleolar RNA SNORA1799542152095421616Rat
41128648Gapdh-ps40Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 4099735703597358357Rat
41293215LOC120094986U6 spliceosomal RNA99390673393906836Rat
41320137LOC120094925small nucleolar RNA SNORA1799712804597128175Rat
41133306LOC120094756uncharacterized LOC1200947569100416164100553687Rat
41202132LOC120094979U6 spliceosomal RNA99930440999304515Rat
41233501LOC120094751uncharacterized LOC12009475199591321895960037Rat
40996703LOC120094748uncharacterized LOC12009474899354109493549241Rat
40972669LOC120094890small nucleolar RNA SNORA4499260122092601359Rat
41012887Spcs3-ps1signal peptidase complex subunit 3, pseudogene 199303549493038160Rat
40954341LOC120094865U6 spliceosomal RNA99351284493512931Rat
40965981LOC120094809uncharacterized LOC12009480999398578693989762Rat
41023977Czib-ps1CXXC motif containing zinc binding protein, pseudogene 199657454496583661Rat
41245914LOC120094752uncharacterized LOC12009475299620883596229501Rat
41246614LOC120094950U1 spliceosomal RNA9100241673100241835Rat
41051343LOC120094586potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2-like99799691297998894Rat
41317148LOC120094747uncharacterized LOC12009474799342929193434280Rat
41302765LOC120094754uncharacterized LOC12009475499951165699522408Rat
41236287LOC120094926small nucleolar RNA SNORA1799894837498948498Rat
41069405LOC120094753uncharacterized LOC12009475399636047096409723Rat
41021246Trnap-agg31transfer RNA proline (anticodon AGG) 3199839748698397567Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
36027D9Rat31349100929646100929786Ratregion
37312D9Rat10010199465802494658115Ratregion
36803D9Rat5015099355248293552632Ratregion
38036D9Rat6420199249158992491790Ratregion
38902D9Rat8324599294927192949515Ratregion
41600D9Rat11017499541071195410867Ratregion
44657D9Got11617099279342392793590Ratregion
44658D9Got11916499352575193525915Ratregion
44659D9Got11522899340536993405597Ratregion
44660D9Got12018499581054095810719Ratregion
44661D9Got12129699413659594136891Ratregion
44662D9Got11818799511644195116628Ratregion
44663D9Got12221999439383294394051Ratregion
44665D9Got12518099787255897872738Ratregion
1639198D9Got24412299363833293638454Ratregion
1640795D9Got20724599573685795737102Ratregion
1634430D9Got2261559100570902100571233Ratregion
1634430D9Got2261559100571078100571233Ratregion
7193002D2995111199356583993565950Ratregion
5036999AU04987018999352574493525933Ratregion
5026076RH13081718799465053794650724Ratregion
5026076RH13081718799465053794650724Ratregion
720577201.MMHAP9FLA1.seq22099797785897978078Ratregion
5034211RH14178821299376929493769505Ratregion
5034462BE11865615099598895495989104Ratregion
5029073RH14341510499834717398347277Ratregion
5029361RH14450528499434534994345633Ratregion
5029539AI00907918199394820993948390Ratregion
5029567AI54812010399301412693014229Ratregion
5035152BQ19586320699369052093690726Ratregion
5029571BE09567018699339800993398195Ratregion
5035376AI17052615599819143698191591Ratregion
5027195AI6426979699383386793833963Ratregion
5029933BE10335718099348819993488379Ratregion
5032715RH13503319299347263793472829Ratregion
5030449BE10649917099599355395993723Ratregion
5027915RH11824416399844017498440337Ratregion
5025538RH12871119599384263393842828Ratregion
5030787BE12002617699440764894407824Ratregion
5025752RH12952619299434603494346226Ratregion
5028380AI43001016499351007393510237Ratregion
5051224RH13451119499383000893830202Ratregion
5051310U795238999827136398271452Ratregion
5053627RH14275810799434463494344741Ratregion
5056041RH14414911099812457498124684Ratregion
5056077RH14416910399806165498061757Ratregion
5056165RH14422129899799561797995915Ratregion
5059424AW53070118399391477893914961Ratregion
5059748BE10314215999399612293996281Ratregion
5058216BF38681317999398952393989702Ratregion
5058272BF38691219899416049994160697Ratregion
5052241D2995110499356582693565930Ratregion
5058434BE09606518599436722594367410Ratregion
5058496BI29054918799383028893830475Ratregion
5059144AI07142319899355975893559956Ratregion
5053425RH14264111199412733594127446Ratregion
5059368BG37774814599258654992586694Ratregion
5057726BE10142215799829372998293886Ratregion
5053617RH14275217599438899494389169Ratregion
5052603RH12588431199362775293628063Ratregion
5054081RH14301914699831437498314520Ratregion
5050854RH13429618699369103293691218Ratregion
5041032RH12862420999416200894162217Ratregion
5043574RH13010318299383365293833834Ratregion
5043992RH13034818999368453193685110Ratregion
5044172RH13045118099844053998440719Ratregion
5044812RH13081819299390972993909921Ratregion
5049322RH13341421399431383594314048Ratregion
5046806RH13196521599391689593917110Ratregion
5049458RH13349215899423428594234443Ratregion
5049686RH13362319199342381893424009Ratregion
5043110RH12983818099300711193007291Ratregion
5040668RH12841519199436756694367757Ratregion
5040972RH12858921499405093194051145Ratregion
5043826RH13025018799599019495990381Ratregion
5072754RH13703319399351022393510416Ratregion
5080610RH14167919099391053793910727Ratregion
5077280RH13966521399805955498059767Ratregion
5076440RH13917612099812220198122321Ratregion
5077948RH14005420999436686694367075Ratregion
5078150RH14017218999874240098742590Ratregion
5078838RH14058118499416808594168269Ratregion
5072980RH13716518999348587893486067Ratregion
5063458BI30183415599892649798926652Ratregion
5067402AU04777223399839658298396815Ratregion
5067510AU04770118499920269199202875Ratregion
5067570AU04766616099839932398399483Ratregion
5067580AU04766022399839933498399557Ratregion
5068422AU04715517099307358693073756Ratregion
5069202AU04665113299289451792894646Ratregion
5065406AA92414419599424265794242852Ratregion
5063822AW53536816799402190294022069Ratregion
5060608BE10407715599849273998492894Ratregion
5062170BE11287317799416209494162271Ratregion
5064112BE11406121499833979598340009Ratregion
5061076BG3794739299384443393844525Ratregion
5084398AI17670719499416134494161538Ratregion
5087088BE10699317099822665398226823Ratregion
5087313BM38950116899961419399614361Ratregion
5082961BF39049015699415662394156779Ratregion
5090571AU04983122399286189092862113Ratregion
5085161AW53258715899831720498317362Ratregion
5085647AI23079716699836648998366655Ratregion
5082657BE11994618299391380793913989Ratregion
5082977BF39053815399341786993418022Ratregion
5083329BF41786917199393921593939386Ratregion
5081631BF41427913199404859994049469Ratregion
5085824BF38816815999321699993217158Ratregion
5503160ZNF207-114499475869794758840Ratregion
5504332D17S1516E16899475900494759158Ratregion
5504855ha256484399586065595861498Ratregion
5506129UniSTS:4984317499342290593422979Ratregion
5500669RH1365902229100601827100602044Ratregion
5499705UniSTS:23417413199250753492507665Ratregion
5506096UniSTS:49834370999342246293423171Ratregion
Position Markers

Flank 1: (D9Rat64)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2992,491,589 - 92,491,790 (+)MAPPER
Rnor_6.0999,041,068 - 99,041,268NCBI
Rnor_5.0998,715,385 - 98,715,585UniSTS
RGSC_v3.4991,131,330 - 91,131,755RGD
RGSC_v3.4991,131,536 - 91,131,736UniSTS
RGSC_v3.1991,336,305 - 91,336,505RGD
Celera990,031,087 - 90,031,287UniSTS
RH 3.4 Map9786.3UniSTS
RH 3.4 Map9786.3RGD
RH 2.0 Map9949.6RGD
SHRSP x BN Map960.2299RGD
FHH x ACI Map963.26RGD
Peak: (D9Rat64)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2992,491,589 - 92,491,790 (+)MAPPER
Rnor_6.0999,041,068 - 99,041,268NCBI
Rnor_5.0998,715,385 - 98,715,585UniSTS
RGSC_v3.4991,131,330 - 91,131,755RGD
RGSC_v3.4991,131,536 - 91,131,736UniSTS
RGSC_v3.1991,336,305 - 91,336,505RGD
Celera990,031,087 - 90,031,287UniSTS
RH 3.4 Map9786.3UniSTS
RH 3.4 Map9786.3RGD
RH 2.0 Map9949.6RGD
SHRSP x BN Map960.2299RGD
FHH x ACI Map963.26RGD
Flank 2: (D9Rat3)
Rat AssemblyChrPosition (strand)Source
mRatBN7.29100,929,646 - 100,929,786 (-)MAPPER
Rnor_6.09107,878,387 - 107,878,528NCBI
Rnor_5.09107,462,655 - 107,462,796UniSTS
RGSC_v3.4999,799,760 - 99,799,902RGD
RGSC_v3.4999,799,761 - 99,799,902UniSTS
RGSC_v3.19100,009,240 - 100,009,382RGD
Celera998,358,237 - 98,358,378UniSTS
SHRSP x BN Map969.3899UniSTS
SHRSP x BN Map969.3899RGD
FHH x ACI Map977.9RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)977813894101597663Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)979271511102910209Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)992491589100929786Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general rats were on a high sucrose diet (HSD; 70% calories as sucrose) and OGTT was performed after over-night fasting at 0 minutes after the administration of glucose 1580752
qtl_statistics_details specific pairs of variables were compared by one or two way ANOVA with post hoc Tukey's honest significance difference test 1580752