Rf54 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Rf54 (Renal function QTL 54) Rattus norvegicus

Symbol: Rf54
Name: Renal function QTL 54
RGD ID: 1581505
Trait: kidney physiology trait   (VT:0002136)    
Measurement Type: kidney 20-HETE level   (CMO:0001854)    
LOD Score: Not Available
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25128,033,842 - 133,011,550RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.05133,313,668 - 138,454,239RGD_MAPPER_PIPELINERnor6.0
Rnor_5.05137,107,818 - 142,265,366RGDRnor5.0
RGSC_v3.45134,871,897 - 139,996,194RGDRGSC3.4
RGSC_v3.15134,877,128 - 140,001,420RGD
Cross Type: Not Available
Strains Crossed: SS.LEW-(D5Rat130-D5Rat31)/JrMcwi SS.LEW-(D5Rat130-D5Rat108)/JrMcwi 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Cyp4a2 is a candidate Gene for Rf54
Cyp4a1 is a candidate Gene for Rf54
Cyp4a8 is a candidate Gene for Rf54
Cyp4a3 is a candidate Gene for Rf54

Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
kidney 20-HETE level  IDA 1578407 RGD 

Experimental Condition
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
controlled sodium content diet  IDA 1578407 RGD 

Measurement Method
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
high-performance liquid chromatography  IDA 1578407 RGD 

Rat Strain
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
SS.LEW-(D5Rat130-D5Rat108)/JrMcwi  IEA 1578407 RGD 
SS.LEW-(D5Rat130-D5Rat31)/JrMcwi  IEA 1578407 RGD 

Vertebrate Trait
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
kidney physiology trait  IDA 1578407 RGD 

Disease Annotations     Click to see Annotation Detail View

Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Characterization of blood pressure and renal function in chromosome 5 congenic strains of Dahl S rats. Roman RJ, etal., Am J Physiol Renal Physiol. 2006 Jan 5;.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1586386Trabd2bTraB domain containing 2B5127941198128158946Rat
41015876LOC120102951uncharacterized LOC1201029515128269299128297520Rat
1304642Foxd2forkhead box D25128427986128430709Rat
11398866LOC108351105uncharacterized LOC1083511055128430904128442177Rat
621727Foxe3forkhead box E35128444912128446494Rat
1310116Cmpk1cytidine/uridine monophosphate kinase 15128480301128507830Rat
1304972StilSTIL, centriolar assembly protein5128520837128573732Rat
1306748Tal1TAL bHLH transcription factor 1, erythroid differentiation factor5128586776128600976Rat
41126986LOC120102952uncharacterized LOC1201029525128612314128619258Rat
620952Pdzk1ip1PDZK1 interacting protein 15128618050128623131Rat
41400278Trnap-agg66transfer RNA proline (anticodon AGG) 665128635289128635369Rat
628719Cyp4x1cytochrome P450, family 4, subfamily x, polypeptide 15128651681128683338Rat
628846Cyp4a8cytochrome P450, family 4, subfamily a, polypeptide 85128702130128733476Rat
40981232Mcts1-ps1MCTS1, re-initiation and release factor, pseudogene 15128728574128729067Rat
1562603Cyp4a8-ps1cytochrome P450, family 4, subfamily a, polypeptide 8, pseudogene 15128827304128852403Rat
41096017Pkm-ps4pyruvate kinase M1/2, pseudogene 45128906060128907436Rat
41170167H3f3cl1H3 histone, family 3C like 15128921288128921701Rat
2479Cyp4a2cytochrome P450, family 4, subfamily a, polypeptide 25128922355128934188Rat
41339692Cyp4a2-ps1cytochrome P450, family 4, subfamily a, polypeptide 2, pseudogene 15128967020128975566Rat
41245892Pkm-ps5pyruvate kinase M1/2, pseudogene 55128992798128994173Rat
41174391H3f3l2H3.3 histone like 25129008176129008589Rat
41366809Cyp4a2l1cytochrome P450, family 4, subfamily a, polypeptide 2 like 15129010501129021087Rat
40980620Cyp4a2-ps2cytochrome P450, family 4, subfamily a, polypeptide 2, pseudogene 25129053886129062415Rat
1584917Pkm-ps13pyruvate kinase M1/2, pseudogene 135129079590129081630Rat
631356Cyp4a3cytochrome P450, family 4, subfamily a, polypeptide 35129097571129115488Rat
68945Cyp4a1cytochrome P450, family 4, subfamily a, polypeptide 15129123323129137464Rat
2480Cyp4b1cytochrome P450, family 4, subfamily b, polypeptide 15129139019129176860Rat
1584916Fdps-ps2farnesyl diphosphate synthase, pseudogene 25129169497129172588Rat
1310351Efcab14EF-hand calcium binding domain 145129218139129258628Rat
1585134Tex38testis expressed 385129260652129265086Rat
41351766LOC120102955uncharacterized LOC1201029555129263054129265721Rat
1305417Atpaf1ATP synthase mitochondrial F1 complex assembly factor 15129265789129292463Rat
1307821Mob3cMOB kinase activator 3C5129306255129315264Rat
1559603Mknk1MAPK interacting serine/threonine kinase 15129318128129357641Rat
1584061Kncnkinocilin5129363464129366907Rat
41051438Tmem275transmembrane protein 2755129376602129377135Rat
1308265Dmbx1diencephalon/mesencephalon homeobox 15129394221129403040Rat
61808Faahfatty acid amide hydrolase5129479774129499018Rat
1559652Nsun4NOP2/Sun RNA methyltransferase 45129511224129532498Rat
1305987Uqcrhubiquinol-cytochrome c reductase hinge protein5129545978129554173Rat
1311221Lrrc41leucine rich repeat containing 415129554547129575450Rat
1310600Rad54lRAD54 like5129575431129605100Rat
1566001Lurap1leucine rich adaptor protein 15129618926129628651Rat
1359396Pomgnt1protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)5129634274129644150Rat
1303308Tspan1tetraspanin 15129646139129659383Rat
6491750P3r3urfPIK3R3 upstream open reading frame5129656654129673140Rat
11457244Trnap-agg7transfer RNA proline (anticodon AGG) 75129690563129690637Rat
41345979LOC120103122uncharacterized LOC1201031225129690639129700956Rat
621042Pik3r3phosphoinositide-3-kinase regulatory subunit 35129700925129772591Rat
1304573Mast2microtubule associated serine/threonine kinase 25129776293129915502Rat
41291644LOC120103379U6 spliceosomal RNA5129832346129832452Rat
41075354LOC120103199U6 spliceosomal RNA5129952187129952290Rat
41245337Rpl7a-ps20ribosomal protein L7a, pseudogene 205129956798129962912Rat
1306299Ippintracisternal A particle-promoted polypeptide5129962528130001237Rat
1561569Tmem69transmembrane protein 695130004888130008466Rat
1359562Gpbp1l1GC-rich promoter binding protein 1-like 15130009768130050636Rat
1598211Ccdc17coiled-coil domain containing 175130051158130056676Rat
1359609Naspnuclear autoantigenic sperm protein5130057363130083003Rat
68346Akr1a1aldo-keto reductase family 1 member A15130092945130130277Rat
41326116LOC120103189U6 spliceosomal RNA5130107105130107211Rat
620039Prdx1peroxiredoxin 15130147258130162856Rat
1310806Mmachcmetabolism of cobalamin associated C5130166056130172735Rat
1564486Ccdc163coiled-coil domain containing 1635130172014130178934Rat
619984Tesk2testis associated actin remodelling kinase 25130178715130270594Rat
1582959Rps26l4ribosomal protein S26 like 45130239204130239590Rat
1309094Toe1target of EGR1, exonuclease5130270484130274050Rat
620045MutyhmutY DNA glycosylase5130274034130286149Rat
1310014Hpdl4-hydroxyphenylpyruvate dioxygenase-like5130286627130288233Rat
2320713Rps20-ps2ribosomal protein S20, pseudogene 25130298198130298740Rat
7649714LOC102550980uncharacterized LOC1025509805130311847130319039Rat
41199780LOC120103232U6 spliceosomal RNA5130338326130338430Rat
1310741Zswim5zinc finger, SWIM-type containing 55130346733130463791Rat
40952488Rpl18-ps4ribosomal protein L18, pseudogene 45130421387130428225Rat
3946Uroduroporphyrinogen decarboxylase5130464695130468783Rat
1309823Hectd3HECT domain E3 ubiquitin protein ligase 35130469840130479802Rat
7638959LOC10255530740S ribosomal protein S12-like5130485611130486622Rat
620821Eif2b3eukaryotic translation initiation factor 2B subunit gamma5130492167130558692Rat
1309039Ptch2patched 25130571956130592506Rat
2320529Btbd19BTB domain containing 195130596966130605403Rat
1565942Dynlt4dynein light chain Tctex-type 45130605437130607224Rat
62039Plk3polo-like kinase 35130607142130612317Rat
1596200Best4bestrophin 45130622194130629045Rat
61910Rps8ribosomal protein S85130630362130632932Rat
41105011Snord38bsmall nucleolar RNA, C/D box 38B5130630642130630711Rat
41246695Snord38asmall nucleolar RNA, C/D box 38A5130631069130631136Rat
41375413Snord46small nucleolar RNA, C/D box 465130632015130632118Rat
41205584Snord55small nucleolar RNA, C/D box 555130632614130632692Rat
620239Kif2ckinesin family member 2C5130637347130662680Rat
41216010Trnaa-agc53transfer RNA alanine (anticodon AGC) 535130664760130664832Rat
41391363LOC120103376U5 spliceosomal RNA5130667018130667133Rat
41150489LOC120103377U5 spliceosomal RNA5130673379130673494Rat
41012747LOC120103378U5 spliceosomal RNA5130680654130680769Rat
1563714Armh1armadillo-like helical domain containing 15130680955130722062Rat
1307066Tmem53transmembrane protein 535130721780130737692Rat
1598210Rnf220ring finger protein 2205130739173130961386Rat
1596047Rps13-ps2ribosomal protein S13, pseudogene 25130966577130967555Rat
1595859Eri3ERI1 exoribonuclease family member 35131016146131143347Rat
1311295Dmap1DNA methyltransferase 1-associated protein 15131143726131151760Rat
41244502Isca1-ps3iron-sulfur cluster assembly 1, pseudogene 35131198540131199066Rat
7691700LOC102553953uncharacterized LOC1025539535131201325131203990Rat
9186911Klf18lKruppel-like factor 18 like5131226565131228325Rat
41326971Isca1-ps2iron-sulfur cluster assembly 1, pseudogene 25131247516131248341Rat
1307711Klf17KLF transcription factor 175131293068131315878Rat
621243Slc6a9solute carrier family 6 member 95131374562131408733Rat
1562911Ccdc24coiled-coil domain containing 245131398766131412395Rat
41390291LOC120102957uncharacterized LOC1201029575131411481131417615Rat
1305358B4galt2beta-1,4-galactosyltransferase 25131412541131422573Rat
1308303Atp6v0bATPase H+ transporting V0 subunit B5131423384131424900Rat
40962025LOC120102958uncharacterized LOC1201029585131424452131427443Rat
1304634Dph2diphthamide biosynthesis 25131428434131431394Rat
620071Ipo13importin 135131433770131454044Rat
621427Artnartemin5131458596131470193Rat
68414St3gal3ST3 beta-galactoside alpha-2,3-sialyltransferase 35131470348131670794Rat
40986348LOC120102962uncharacterized LOC1201029625131488037131489093Rat
41129363LOC120102961uncharacterized LOC1201029615131488481131492415Rat
7747039LOC102553361uncharacterized LOC1025533615131535622131540841Rat
41119943LOC120102959uncharacterized LOC1201029595131567330131572307Rat
41337843LOC120102960uncharacterized LOC1201029605131587421131591432Rat
1306378Kdm4alysine demethylase 4A5131672754131719534Rat
3453Ptprfprotein tyrosine phosphatase, receptor type, F5131741959131824000Rat
7559302LOC102553423uncharacterized LOC1025534235131809376131814053Rat
1561416Hyihydroxypyruvate isomerase5131894575131897709Rat
1308616Szt2SZT2 subunit of KICSTOR complex5131897250131943953Rat
1305552Med8mediator complex subunit 85131948632131949516Rat
1587151Elovl1ELOVL fatty acid elongase 15131961478131965961Rat
620477Cdc20cell division cycle 205131966203131970406Rat
9354806LOC103692460uncharacterized LOC1036924605131970623131974793Rat
1311069MplMPL proto-oncogene, thrombopoietin receptor5131973895131987472Rat
41271559LOC120103206U6 spliceosomal RNA5131979522131979625Rat
7625538LOC102554074uncharacterized LOC1025540745131986391131999442Rat
621642Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 15132000013132019658Rat
1587100Tmem258l2transmembrane protein 258 like 25132041753132042174Rat
1587085Rps5-ps1ribosomal protein S5, pseudogene 15132042844132043482Rat
1305347C5h1orf210similar to human chromosome 1 open reading frame 2105132048755132051913Rat
1311937Tmem125transmembrane protein 1255132063162132064566Rat
1585948Cfap57cilia and flagella associated protein 575132074404132148102Rat
41196424LOC12010296360S ribosomal protein L21-like5132123799132128190Rat
1305762Ebna1bp2EBNA1 binding protein 25132148164132152730Rat
11479750LOC108351020uncharacterized LOC1083510205132160198132164045Rat
1333931Or13p10olfactory receptor family 13 subfamily P member 105132186704132187651Rat
1332845Or13p9olfactory receptor family 13 subfamily P member 95132203917132204855Rat
1333749Or13p4olfactory receptor family 13 subfamily P member 45132216822132217769Rat
1333843Or13p3olfactory receptor family 13 subfamily P member 35132236461132237399Rat
1584354Or13p8bolfactory receptor family 13 subfamily P member 8B5132250763132255279Rat
1333211Or13p5olfactory receptor family 13 subfamily P member 55132261753132265386Rat
1333268Or10ak14bolfactory receptor family 10 subfamily AK member 14B5132271846132272793Rat
41245460LOC120093079olfactory receptor 2A12-like5132293815132294801Rat
1334007Or10ak14olfactory receptor family 10 subfamily AK member 145132312678132313619Rat
1584753Olfr1330-ps1olfactory receptor 1330, pseudogene 15132326454132327460Rat
1583684Or10ak11olfactory receptor family 10 subfamily AK member 115132345164132346165Rat
1333331Or10ak7bolfactory receptor family 5 subfamily AK member 7B5132373994132374941Rat
1332921Or10ak7folfactory receptor family 10 subfamily AK member 7F5132407421132408368Rat
1334318Or10ak13olfactory receptor family 10 subfamily AK member 135132435679132436626Rat
2318892Rpl36-ps11ribosomal protein L36, pseudogene5132457835132458216Rat
1333113Or10ak7eolfactory receptor family 10 subfamily AK member 7E5132462578132463525Rat
1332893Or10ak7olfactory receptor family 10 subfamily AK member 75132489097132490044Rat
1598117Mrs2-ps1magnesium transporter MRS2, pseudogene 15132496554132497918Rat
1334300Or10ak7d-ps1olfactory receptor family 10 subfamily AK member 7D, pseudogene 15132504419132505360Rat
1334256Or10ak7c-ps1olfactory receptor family 10 subfamily AK member 7C, pseudogene 15132519279132520219Rat
41360569Trnas-aga19transfer RNA serine (anticodon AGA) 195132530789132530871Rat
1333490Or10ak7g-ps1olfactory receptor family 10 subfamily AK member 7G, pseudogene 15132547785132548722Rat
1310787Lao1L-amino acid oxidase 15132573698132583591Rat
41378098LOC120103309small nucleolar RNA SNORA175132591434132591567Rat
6496493Ubb-ps1ubiquitin B, pseudogene 15132604603132605052Rat
11451090LOC108351140NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 pseudogene5132695795132696187Rat
11512073LOC108351021uncharacterized LOC1083510215132706788132717161Rat
3704Slc2a1solute carrier family 2 member 15132717196132745416Rat
1308150Zfp691zinc finger protein 6915132780259132784954Rat
41031036LOC120102964uncharacterized LOC1201029645132783310132785888Rat
1309996Ermaperythroblast membrane associated protein (Scianna blood group)5132788847132803030Rat
1311232Svbpsmall vasohibin binding protein5132808021132813735Rat
1563015Tmem269transmembrane protein 2695132817324132836360Rat
1564804C5h1orf50similar to human chromosome 1 open reading frame 505132837135132841744Rat
628823P3h1prolyl 3-hydroxylase 15132841868132856664Rat
1305000Cldn19claudin 195132862939132870364Rat
61843Ybx1Y box binding protein 15132882137132898885Rat
1564921Ppihpeptidylprolyl isomerase H5132906324132924341Rat
1305604Ccdc30coiled-coil domain containing 305132926767133019635Rat
41262339Trnaa-agc98transfer RNA alanine (anticodon AGC) 985132993684132993764Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10453D5Mcw15128924597128924722Ratregion
10453D5Mcw15129098900129099033Ratregion
10454D5Wox121185128924607128924723Ratregion
10454D5Wox121185129098910129099034Ratregion
34581D5Mgh272445129132447129132675Ratregion
34583D5Rjr11905129132428129132602Ratregion
11303D5Wox111285132743341132743469Ratregion
11304D5Arb72325132744136132744368Ratregion
33680D5Mit132025131345754131345958Ratregion
33731D5Mit141895131378081131378254Ratregion
36187D5Rat301605128499722128499884Ratregion
36677D5Rat311745133011384133011550Ratregion
36711D5Rat321645132686313132686472Ratregion
35060D5Rat291705129406121129406289Ratregion
39606D5Rat1642205128477950128478162Ratregion
38338D5Rat1081995128033842128034027Ratregion
38828D5Rat902085132691196132691399Ratregion
39352D5Rat872355132649285132649528Ratregion
42756D5Rat2612015129410089129410272Ratregion
42757D5Rat2352015129441624129441817Ratregion
41288D5Rat1661675130881210130881381Ratregion
41388D5Rat1671285131581900131582032Ratregion
41448D5Rat1681755131837785131837966Ratregion
41630D5Rat1991275129390389129390500Ratregion
41686D5Rat2012165129712378129712586Ratregion
41704D5Rat2002085129140953129141153Ratregion
43962D5Got501305128398386128398516Ratregion
43964D5Got572115128486224128486435Ratregion
43967D5Got552385129379994129380224Ratregion
43968D5Got591785131352850131353030Ratregion
43969D5Got583185132081000132081312Ratregion
43970D5Got612795132914427132914706Ratregion
43971D5Got561905131284754131284944Ratregion
60490D5Got512275128579225128579453Ratregion
60491D5Got521805130517403130517585Ratregion
69509D5Uwm592005131830143131830331Ratregion
69561D5Uwm352385128627218128627457Ratregion
69569D5Uwm381805132207401132207589Ratregion
66424D5Mco73125129320195129320521Ratregion
1631411D5Wox405131965869131966040Ratregion
1628544D5Wox285131392020131392174Ratregion
1633333D5Wox292225131372552131372774Ratregion
5038628AA414954805129772164129772244Ratregion
5038630AW8220002515130479423130479674Ratregion
7206600Foxd29435128428216128429159Ratregion
7206602Foxe33905128445627128446017Ratregion
7206636Slc2a105132743856132745113Ratregion
5039030RH1274722185129575169129575387Ratregion
5026074RH1308091925131741998131742190Ratregion
5026228RH1314061865131423416131423602Ratregion
5028895RH1427312335130721158130721391Ratregion
5034552BE1194261795131409081131409260Ratregion
5026786RH1335232035128158643128158846Ratregion
5032263AI8511621325132813332132813460Ratregion
5026956RH1341761865131896955131897227Ratregion
5029627BE1017482055130462668130462873Ratregion
5029633BF3864182095131121135131121346Ratregion
5029811BE1028271775131693813131693990Ratregion
5027591BB151133925131965773131965865Ratregion
5030111BE1104471705129614175129614346Ratregion
5032951RH1370781845132152339132152659Ratregion
5030255BE1115832155132497971132498186Ratregion
5030329BE1058591895130927292130927478Ratregion
5033083RH1375291285132837190132837318Ratregion
502793936.MMHAP9FRD12.seq1745129625990129626164Ratregion
5030815BE1203221845131139870131140055Ratregion
5033563RH1392821225129771669129771791Ratregion
5025654RH1291462005129137262129137462Ratregion
5025658RH1291631925130607151130607343Ratregion
5051993RH947772215132711415132711636Ratregion
5054871RH1434731775131405819131405996Ratregion
5054881RH1434782675132061987132062254Ratregion
5056241RH1442651245129700290129700414Ratregion
5056275RH1442841355130052194130052329Ratregion
5058854BF3871872065131813851131814057Ratregion
5058906BF3872161695131971506131971675Ratregion
5055691RH1439471345131897304131897438Ratregion
5058472BE0962161695132870208132870377Ratregion
5054093RH1430261155132843041132843156Ratregion
5050472RH1340762175132748041132748258Ratregion
5052927RH1423541605132837594132837754Ratregion
5051096RH1344372195130000581130000800Ratregion
5043428RH1300201805130478299130478479Ratregion
5041284RH1287681505130270351130270501Ratregion
5044026RH1303672165129314837129315053Ratregion
5046088RH1315512025128217728128218623Ratregion
5044374RH1305661955129772352129772547Ratregion
5044428RH1305972105129290909129291119Ratregion
5046172RH1316001805128923713128923893Ratregion
5046172RH1316001805129010601129010781Ratregion
5046172RH1316001805129098021129098201Ratregion
5047628RH1324372205129513373129513593Ratregion
5046814RH1319701825129480995129481177Ratregion
5048362RH1328601955130004946130005141Ratregion
5042526RH1294881655128600753128600918Ratregion
5049612RH1335812025129480048129480250Ratregion
5039486RH1277331855132051511132051696Ratregion
5040600RH1283761825130056344130056526Ratregion
5043224RH1299032055129293297129293502Ratregion
7192216Slc2a1765132740566132741330Ratregion
5040302RH1282051805131142912131143092Ratregion
5043010RH1297771835129546053129546236Ratregion
5075004RH1383431525132912194132912346Ratregion
5074068RH1378001215131696381131696502Ratregion
5075586RH1386791255129647117129647242Ratregion
5075856RH1388362065130210479130210685Ratregion
5072280RH1367581835130720595130720778Ratregion
5076180RH1390261315129999661129999792Ratregion
5076214RH1390451845131742936131743120Ratregion
5076688RH1393211545131470364131470518Ratregion
5078126RH1401581855129999771129999954Ratregion
5079828RH1412261805131433780131434048Ratregion
5080070RH1413651865129776379129776565Ratregion
5078314RH1402692035128515849128516052Ratregion
5072984RH1371672205130286628130286848Ratregion
5080424RH1415711895128932273128932462Ratregion
5080424RH1415711895129019159129019348Ratregion
5080424RH1415711895129113516129113665Ratregion
5080526RH1416301705130285035130286093Ratregion
5072970RH1371591515129139100129139251Ratregion
5073012RH1371832505128573362128573612Ratregion
5071786RH1352832095129774636129774845Ratregion
5073336RH1373771855132000011132000196Ratregion
5071374RH1350451815128702633128702814Ratregion
5071688RH1352272175130465465130465682Ratregion
5063384BF3988351605130463311130463471Ratregion
5064962BE1087731785129547404129547582Ratregion
5066760AU0481672155129866293129866508Ratregion
5066878AU0480972245131081556131081780Ratregion
5067068AU0479841295128425977128426108Ratregion
5068370AU0471871485130352168130352316Ratregion
5070490Prdx1705130154646130156228Ratregion
5070490Prdx1705130156177130156228Ratregion
5065200BE1211451905130827004130827194Ratregion
5060370AW5318461725130057396130057570Ratregion
5062666BF4037241075130477886130477993Ratregion
5063684BE1079671735129619479129619652Ratregion
5063866BE1201091515129218313129218464Ratregion
5066046BI3041561875130288704130288891Ratregion
5062958BI3010141535129339283129339435Ratregion
5064566BE1081241845132061064132061248Ratregion
5063232BF4105401635131666124131666287Ratregion
5064904BF4052631345130479505130479639Ratregion
5061642BF3969601835132890613132890796Ratregion
5086247AA9570481845130270585130270769Ratregion
5086295BQ2054791905131671841131672031Ratregion
5082497BF4161251045129533011129533115Ratregion
5088098Slc2a11925132744921132745113Ratregion
5089795AU0493682485132207978132208226Ratregion
5087887Glyt12065131408382131408588Ratregion
5089063AU0489332005130620272130620472Ratregion
5089441AU0491581925130216523130216715Ratregion
5089549AU0492212225130432062130433042Ratregion
5083833AA8930112345128702186128702420Ratregion
5088601AU0486671975130620275130620472Ratregion
5088733AU0487472995131352840131353141Ratregion
5089697AU0493092335129454661129454896Ratregion
5084038AA9434401925131399543131399735Ratregion
5084426AI1695731005131586261131586361Ratregion
5085044AI2376341385128337806128337942Ratregion
5081018RH1419171805131408476131408656Ratregion
5085896AW5358801615128562572128562733Ratregion
5080788RH1417822045130166555130166759Ratregion
5080824RH1418041805130637485130637665Ratregion
5082959BF3904891705129223605129223775Ratregion
5081250RH1420521935129509694129509887Ratregion
5084856AI2359971135129610874129610987Ratregion
5084942AA9633881545131965784131965938Ratregion
5083313BF4176501155130427355130427470Ratregion
5081537BE1172641815128592686128592867Ratregion
5503256UniSTS:23755610885130645951130647039Ratregion
5505042Mpl8625131985255131986117Ratregion
5505438Lepre13985132856190132856588Ratregion
5505686UniSTS:4893139545132254325132255279Ratregion
5505921UniSTS:496549945131966929131967934Ratregion
5506177UniSTS:498727675132005377132005444Ratregion
5507013fj50d02.y12385131745458131745796Ratregion
5507059UniSTS:2242831045131423456131423560Ratregion
5507169UniSTS:2249081775131743133131743310Ratregion
5499675MARC_7377-7378:992008389:13855129639150129639535Ratregion
5500599RH1361501995130058470130059440Ratregion
5501816MARC_13905-13906:1007570719:16495130471126130471775Ratregion
5505812UniSTS:49540514285131693710131695138Ratregion
5502172MARC_7381-7382:996687840:1985129484171129485414Ratregion
5502174MARC_7369-7370:996687826:16505131416164131416814Ratregion
5501980MARC_21798-21799:1025034200:11015130267477130267793Ratregion
5501998MARC_23422-23423:1025023955:36175130586175130586792Ratregion
Position Markers

Flank 1: (D5Rat108)
Rat AssemblyChrPosition (strand)Source
mRatBN7.25128,033,842 - 128,034,027 (+)MAPPER
Rnor_6.05133,313,668 - 133,313,852NCBI
Rnor_5.05137,107,818 - 137,108,002UniSTS
RGSC_v3.45134,871,897 - 134,872,385RGD
RGSC_v3.45134,871,902 - 134,872,086UniSTS
RGSC_v3.15134,877,128 - 134,877,312RGD
Celera5126,688,474 - 126,688,658UniSTS
RH 3.4 Map5828.8UniSTS
RH 3.4 Map5828.8RGD
RH 2.0 Map5776.9RGD
SHRSP x BN Map566.0999RGD
Cytogenetic Map5q35UniSTS
Flank 2: (D5Rat31)
Rat AssemblyChrPosition (strand)Source
mRatBN7.25133,011,384 - 133,011,550 (+)MAPPER
Rnor_6.05138,454,074 - 138,454,239NCBI
Rnor_5.05142,265,201 - 142,265,366UniSTS
RGSC_v3.45139,996,029 - 139,996,194UniSTS
RGSC_v3.45139,996,028 - 139,996,194RGD
RGSC_v3.15140,001,255 - 140,001,420RGD
Celera5131,535,894 - 131,536,059UniSTS
RH 3.4 Map5868.1RGD
RH 3.4 Map5868.1UniSTS
RH 2.0 Map5860.3RGD
SHRSP x BN Map570.6499RGD
FHH x ACI Map570.92RGD
Cytogenetic Map5q36UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584132602129132602Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)590067849128034027Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)590067849128034027Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)597570330136479578Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
1582230Bw78Body weight QTL 783.20.0016epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)5119085612128034027Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5120740824143608494Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5120740824151018848Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5124160767133749643Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5125392826139989768Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5128033842133011550Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5129132428143070159Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_disease chromosome 5 QTL region from Lewis rat associated with increased renal production of 20-hydroxyeicosatetraenoic acid (20-HETE), improved pressure-natriuresis, reduced development of salt-induced hypertension 1578407
qtl_map QTL flanking region defined by comparative mapping of congenic strains; p-values reported to be less than 0.05 for renal production of 20-HETE, renal CYP4A protein level, mean arterial pressure, renal perfusion pressure 1578407